Dementia In Elderly Research Articles

Experiences of Family Caregivers in the Process Leading up to the Diagnosis of Elderly Dementia

Experiences of Family Caregivers in the Process Leading up to the Diagnosis of Elderly Dementia

Application of 18-item DEOS for Dementia Elderly People Living at Home and Its Reliability and Validity

Application of 18-item DEOS for Dementia Elderly People Living at Home and Its Reliability and Validity

File-up Stress, Family Hardiness and Mental Health Status in Family Caregivers Caring for Elderly Dementia 

File-up Stress, Family Hardiness and Mental Health Status in Family Caregivers Caring for Elderly Dementia 

Elderly Dementia Patient with Recurrent Respiratory Failure due to the Abuse of a Fentanyl Patch: A Case Report

Elderly Dementia Patient with Recurrent Respiratory Failure due to the Abuse of a Fentanyl Patch: A Case Report

Report of 14 cases of exogenous lipoid pneumonia in the elderly

Objective To investigate the clinical characteristics of exogenous lipoid and to explore the characteristics of the elderly with the disease. Methods 14 cases of elderly patients with exogenous lipoid in Beijing Hospital were analyzed. Results Among the 14 patients(7 male and 7 female), main symptoms included dyspnea(50.0%), cough(35.7%), and the common signs were crackles(28.6%)and wet rales(21.4%). For exogenous lipoid pneumonia, the most common causes of inhalation of lipoid substances included chronic constipation, nasal cavity diseases such as rhinitis(35.7%). Some of elderly dementia patients may wrong inhale lipoid substances(21.4%). X ray or CT features of exogenous lipoid showed a tumor-like mass or lesions(42.9%)and the exudative plaque(64.3%), both of which were easily misdiagnosed as tumor.All of the 14 cases(100%)were misdiagnosed as pneumonia or , and finally confirmed by pathological diagnosis.Among the 14 cases, 2 cases were diagnosed by cytopathology of bronchial alveolar lavage fluid or by transbronchial lung biopsy, 10 cases were diagnosed by invasive examination methods like lobe resection, and 2 cases were confirmed by autopsy.At present, there is still a lack of effective treatment methods for exogenous lipoid pneumonia. Conclusions Due to the basal disease(such as constipation)action, the elderly may easily have access to exogenous lipoid with atypical symptoms, might have more serious manifestations than younger adults, and may have X ray or CT imaging similar to lung cancer or pneumonia.So it is often misdiagnosed.If the patients cannot be timely diagnosed and the causes cannot be removed, it is likely to cause chronic interstitial fibrosis or death.Clinicians must increase the awareness of, and take into account the possibility of lipoid pneumonia, especially meeting the elderly patients with dry cough and dyspnea, rales or crackles and X-ray or CT tumor-like imaging as main manifestation resembling pulmonary inflammation or tumor without treatment futility after common antibiotic treatment. Key words: Lung disease, interstitial; Lipids

PRM46 - A Calculating Analysis Model on Disability Adjusted of Life Years Among Patients Suffering from Alzheimer's: Based on The Improvement of Multi-State Markov Model

Dementia, as well as high blood pressure, diabetes, and coronary heart disease, has become the four largest killers which threaten the elderly's health. As the population all over the world is aging fast, the number of elderly who suffer from dementia has been increasing speedily, thus causing a huge burden of disease to society, families and patients. At present, however, it is not that accurate to employ Disability Adjusted of Life Years (DALY) to calculate the disease burden of dementia because dementia is characterized by long disease course and multi stages and elder dementia sufferers of different health status have difference within cognitive competence and physical activity capacity. Therefore, multi-state Markov Model has been introduced in this paper to formulate an improved calculating analysis model on DALY among patients suffering from Alzheimer's. Firstly, set up weight coefficient of disease and calculate the matrix of transition probability for elderly dementia based on different Markov status. Then, formulate a certain number of conversion models within/between each stage based on different disease characteristics of different stages of elderly dementia. Finally, measure the improved the DALY of patients suffering from Alzheimer's during the whole lifespan by adding up the DALYs of dementia sufferers in all stages. This analysis model has taken the features of elderly dementia into consideration and can truly reflect the Years Lived with Disability of Alzheimer's patients.

A Comparison of Health Perception, Entrapment, Suicidal Ideation, and Care Burden of Main Caregivers of Elderly Dementia Patients According to Depression Status

With the rapid ageing of Korean society, the number of elderly dementia patients is on a sharp increase. Dementia cannot be cured; so, it has long-term effects not only on patients, but on their main caregivers, too. This descriptive comparative study seeks to analyze differences in the health perception, entrapment, suicidal ideation, and care burden of main caregivers of elderly dementia patients according to depression level and to identify the characteristics of elderly dementia patients. The study subjects are the main caregivers of dementia patients registered in dementia support centers under public health facilities in metropolitan areas. Sixty questionnaire copies were analyzed in this study. The results showed that the main caregivers’ depression status had significant correlations with their entrapment (r=.801), suicidal ideation(r=.495), care burden (.562), health perception(r=-.505), and elderly dementia patients’ hearing (p=.01). Given the study results, prevention and treatment of depression among main caregivers of elderly dementia patients may lower their entrapment, suicidal ideation, and care burden. In addition, since caregivers’ depression is related to elderly dementia patients’ hearing, it is necessary to take into account that relationship.

A Study on the Effect of Group Art Therapy Combined with Therapeutic Recreation on the Cognitive Function, Depression, and Interpersonal Relations of Elderly Dementia Patients

A Study on the Effect of Group Art Therapy Combined with Therapeutic Recreation on the Cognitive Function, Depression, and Interpersonal Relations of Elderly Dementia Patients

치매노인의 인지기능 향상을 위한 차문화치료 프로그램

This study is to constitute and develop tea-culture therapy program based on positive psychology, cognitive behavioral theory and past life reminiscence therapy. The program was developed to target the elderly with dementia 10 people admitted to the Geriatric Hospital located in P city. Tea-culture therapy was practiced once a week, 10 sessions of 60 minutes, which divided into 10 minutes for introduction, 40 minutes for intervention activities, and 10 minutes for sharing impression and wrap up. The quantitative effects of this program shows that the participants average pre-score of cognitive function scale was 16.2 (SD 2.66), whereas after-score was 17.9(SD 1.91). Namely, it shows 1. 7 score improvement and it was statistically significant(Z=-3.681, P=.004). According to qualitative analysis, the program shows that participants accepted the positiveness and negativeness of his life naturally, achieved ego integration and promoted happy feeling, through positive emotion experience, anger expression, and forgiveness program and tea-culture activity. Therefore, it confirmed that the tea-culture program developed on the basis of positive psychology and reminiscence therapy is effective for the enhancement of cognitive function of elderly dementia.

DECLINE IN GLUCOSE LEVELS PRECEDES DEMENTIA IN ELDERLY AFRICAN AMERICANS WITH DIABETES

DECLINE IN GLUCOSE LEVELS PRECEDES DEMENTIA IN ELDERLY AFRICAN AMERICANS WITH DIABETES

The effect of folk recreation program in improving symptoms: a study of Chinese elder dementia patients.

This study aimed to evaluate the effects of a folk recreation program on the symptoms of people with dementia. The program was tailored to the participants' interest and derived from their traditional culture background. A quasi-experimental study design was used. A total of 48 participants were assigned to an experimental or a control group. The experimental group received a 40 to 50-min folk recreation intervention, which is mainly about art, music and game, three times a week and for 16 weeks. The control group received routine care without special intervention. The Mini-mental State Examination (MMSE), Barthel Index (BI) and the Chinese version of the neuropsychiatric inventory (CNPI) were used to estimate the cognitive function, ability of daily living and behavioral and psychological symptoms with dementia at baseline and week 16. For the experimental group, the mean scores of MMSE and BI increased significantly from baseline to week 16 (p < 0.01) for cognitive function and activity of daily living, and the mean score of CNPI-symptom decreased significantly (p < 0.01) for behavioral and psychological symptoms. While, for the control group, the mean score of MMSE decreased significantly (p < 0.01), and the mean scores of BI and CNPI-symptom changed non-significantly. The folk recreation program has the potential to improve cognitive function, ability of daily living and behavioral and psychological symptoms of the elders with dementia. The folk leisure activities, which embed in the participants' cultural background, will motivate their positive feelings and memories, can delay the progression of disease and improve the symptoms. Copyright © 2016 John Wiley & Sons, Ltd.

Case Report: Marked Effect of Cilostazol on Delirium in a Dementia Patient with Deep White Matter Lesions: Potential Etiology- Targeted Pharmacotherapy for Delirium

Antipsychotics have been mainly used as pharmacotherapy for delirium. Their use is, however, only considered a symptom-targeted, but not an etiology-targeted therapy. Moreover, antipsychotics may also have some adverse effects in elderly patients. We report a case of an elderly dementia patient with deep white matter lesions whose delirium was markedly resolved with a platelet aggregation inhibitor, cilostazol. No antipsychotic drugs were used. To our knowledge, there have been no reports regarding the effect of cilostazol on delirium, despite not a few studies on cognitive function of Alzheimer disease and cerebrovascular disease. This case suggests that cilostazol is a potentially effective agent as an etiology-targeted therapy for delirium due to its possible increased regional cerebral blood flow.

Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study

BackgroundAntipsychotics are commonly used to manage behavioral and psychological symptoms of dementia. Concerns over their safety and efficacy in this role have resulted in antipsychotics typically being recommended for short-term usage only when used among dementia patients. However, there is little work examining the duration of antipsychotic treatment in the elderly dementia patient population.ObjectiveTo determine the persistence of use of antipsychotics in elderly dementia patients and the role of dose on therapy duration.MethodsA retrospective, population-based cohort study using administrative data, including dispensing records from a provincial public drug program, from Ontario, Canada between 2009 and 2012. Elderly dementia patients newly initiated onto antipsychotics were followed until drug discontinuation, death, 2-year follow-up, or end of study. Competing risk analysis was performed to determine time to discontinuation, stratified by categories of initial dose.ResultsAfter 2 years 49.1 % of the cohort (N = 22,927 of 46,695) had discontinued treatment. When stratified by dose, the high-dose group (51.1 % discontinued) discontinued more frequently than the medium- (48.7 % discontinued) and low- (47.5 % discontinued) dose groups (p < 0.0001).ConclusionApproximately half of elderly dementia patients treated with antipsychotics discontinue within 2 years, with those on higher doses more likely to discontinue. However, the number of patients remaining on therapy represents a serious public health concern.

Effect of Psychological Factors After Applying the Reminiscence Program With Media in Dementia Elderly

The aim of present study was to the clarify effect of depression and quality of life after applying the reminiscence program with film media in elderly dementia patients. The subjects was selected as patients to be diagnosed by dementia and over 65 years. The ego integrity resulted in reminiscence program through media tools had statistically significant difference between pre-and post program (p .05). The quality of life is also not statistically significant difference, but the total score of role physical, bodily pain and vitality item was a positive increase. In this study, the reminiscence program Received(October 19, 2015), Review request(October 20, 2015), Review Result(1st: November 18, 2015, 2nd: December 26, 2015) Accepted(January 04, 2016), Published(January 31, 2016) Dept. of Occupational Therapy, Semyoung University email: apolius@naver.com Dept. of Occupational Therapy, Woosong University email: 2000choeun@hanmail.net (Corresponding Author) Institute for health promotion, Wonkwang University email: otprime@wku.ac.kr Effect of Psychological Factors After Applying the Reminiscence Program With Media in Dementia Elderly Copyright c 2016 HSST 68 included with media tools can be confirmed to positively effect for depression and quality of life in elderly dementia patients. It was the opportunity to see the positive effects for dynamic film media tools like positive effects of earlier studies using a static media tools. Also, we thinks that the reminiscence program applied for healthy elderly was a meaningful chance due to having a positive result for cognitive disability subjects.

Effect of Dance Performing Arts Therapy Program on the Depression, Anxiety and Shoulder Movement Mobility of Elderly Dementia Patients

Effect of Dance Performing Arts Therapy Program on the Depression, Anxiety and Shoulder Movement Mobility of Elderly Dementia Patients

A clinical analysis of elderly dementia patients with physical comorbidities

To investigate the current status of elderly dementia patients with physical illnesses and identify optimal care strategies for this growing population. This retrospective study included elderly dementia patients who (i) received in-patient treatment for a physical comorbidity at the dementia ward of the Juntendo Tokyo Koto Geriatric Medical Center, and (ii) who were discharged from April 2009 to March 2011. The study population was 390 patients (144 males, 246 females), with a mean [±SD] age of 80.5 [±8.1] years. Two hundred thirteen of the patients had Alzheimer's disease; the remaining 177 had other types of dementia. The comorbidities necessitating admission were: malignant neoplasms (n=65), respiratory conditions (n=57), genitourinary conditions (n=50), trauma or fracture (n=41), and other (n=177). Among the 239 subjects who were hospitalized from their homes and who were discharged alive, 157 (65.7%) returned to their homes. The hospital stays of patients who were discharged were significantly shorter (P<0.000) and their N-ADL scores were significantly better at admission (P<0.013) and at discharge (P<0.000). The proportion of subjects who were capable of oral ingestion was significantly higher among the patients who were discharged to their homes (P<0.025). The subjects who lived in their homes alone at the time of hospitalization were significantly less likely to be discharged to their homes (P<0.018). Elderly dementia patients should ideally return home after hospitalization for comorbid illnesses. This was facilitated by minimizing their hospital stay. During in-patient treatment, efforts should be made to maintain their N-ADL levels and support their oral intake.

Study on Dementia Elderly Service Management Status in Local Community of Korea

Study on Dementia Elderly Service Management Status in Local Community of Korea

Functioning and disability analysis by using WHO Disability Assessment Schedule 2.0 in older adults Taiwanese patients with dementia

Background: To analyse the disability status of elderly Taiwanese dementia patients by using the World Health Organisation Disability Assessment Schedule 2.0 (WHODAS 2.0). Methods: We enrolled 12 126 disabled elderly (>65 years) patients with dementia during July 2012–January 2014 from the Taiwan Data Bank of Persons with Disability. Trained interviewers evaluated the standardised scores in the six WHODAS 2.0 domains. Student’s t test was used for comparing WHODAS 2.0 scores of male and female dementia patients with different age groups. Results: The study population comprised 12 126 patients; 7612 were women and 4514 were men. The WHODAS 2.0 scores showed that the dementia patients had global activity limitation and participation restriction in all domains. Dementia-induced disability was prominent in male patients in all of the domains of the WHODAS 2.0. The domains of life activities, getting along with people and cognition were more strongly affected than the other domains. However, women experienced more rapid functional decline than men did as they aged. Conclusion: The data analysed in this large-scale, population-based study revealed crucial information on dementia-induced disability in elderly patients on the basis of the WHODAS 2.0 framework.Implications for rehabilitationDementia patients have global functional disability in all domains of WHODAS 2.0 and multidisciplinary team is needed for rehabilitation programme intervention for these patients.When considering the rehabilitation resource and strategy, the domains of cognition, activities of daily living and life activities should be focussed.When dementia patients aged 65–75 years old, male patients got more restriction of function than female and more medical resource allocation for disabled male patients is recommended.With ageing, female dementia patients exhibited more rapid functional decline than male patients did and more budget about rehabilitation for maintain functional and dementia progression is crucial for female patients.

Investigation of low amyloid level toxicity effects on the function of hippocampal neurons

Abstract Alzheimer disease (AD) is responsible for the majority of elderly dementia cases. There are multiple mouse models of AD, however, none of them completely recapitulate human pathology. Moreover, it is even more difficult to imitate the onset of the disease in experimental models. In the current study we analyzed the influence of low amyloid level toxicity on the function of hippocampal neurons. Our assay is based on use of synthetic oligomeric amyloid beta peptides. These peptides were added to primary hippocampal cultures at a physiological nanomolar range to mimic early AD. Calcium imaging was used to evaluate the functionality of the assay. A low amyloid level toxicity assay could be useful for fundamental research as well as for testing newly developed AD drugs.

쪽방촌 노인의 인지기능과 치매 인식도에 대한 연구

쪽방촌 노인의 인지기능과 치매 인식도에 대한 연구