The transition between a tide-dominated estuary and a tide-dominated delta, which is observed in modern settings and repeatedly throughout the geologic record, is a critical process for understanding sea-level and environmental changes. This transition remains poorly documented, however, leaving a knowledge gap about the sedimentary and stratigraphic processes involved. To help bridge the gap, we reexamined the postglacial transgressive system beneath the modern Changjiang (Yangtze River) Delta, built by one of the world’s largest rivers, using new chirp data supplemented by correlation with previously documented boreholes. Our results revealed a previously undocumented tide-dominated estuary-to-delta transition around the Younger Dryas, with the pretransition evolution dominated by the retrogradation of the tide-dominated estuary, which fills most of the accommodation space in the lowstand incised valley. This transition occurred when the middle and seaward parts of the estuary reached the subaqueous modern Changjiang Delta area and underwent extensive tidal erosion. Overlying the tidal ravinement, a series of ridge-and-swale structures formed due to tidal/fluviotidal channelization on the mud-dominated heterolithic substrate, primarily consisting of delta-front sediments characterized by flat, stratified reflections (bedding) with shallowing-upward trends. Ridge orientation rotates clockwise from north to south, with intervening swales bifurcating from a common apex point, and these features are flanked by inclined and sigmoidal levee-like channel fills dominated by homogeneous mud (acoustically transparent material). We reinterpret these features as tide-dominated delta islands and distributary channels, rather than the previously interpreted erosional mud ridges in the seaward part of the estuary, as they align with patterns observed in classic tide-dominated deltas. These patterns also suggest a shift from delta-front to delta-plain environments coinciding with shoreline advance ca. 10 k.y. B.P., but this was preceded by the evolution of a backstepping delta. Our study highlights the interplay between sediment supply and sea-level fluctuations in controlling the large-scale stratigraphic and environmental evolution of tidal-dominated river mouth systems. In the transgressive, paleo-Changjiang mouth, this interplay drove the system to evolve through stages of retrogradational estuary, backstepping delta, and progradational delta, and each environment differs significantly from the pattern observed in the modern Changjiang Delta. This study provides important insights for evaluating the evolution and sequence-stratigraphic reconstruction of other tidal depositional systems.