Degree Of Depressive Symptoms Research Articles

PREVIDA- IMPACT OF VORTIOXETINE ON MAJOR DEPRESSIVE DISORDER AND PERCEIVED COGNITIVE DYSFUNCTION: A MULTICENTER STUDY

Objective: To find out how common cognitive impairment is in people with major depressive disorder (MDD) and assess how well vortioxetine works for treating both cognitive dysfunction and depressive symptoms. Study Design: Multi-centred, Cross-sectional, prospective follow up design Place & Duration of Study: The research took place over the course of 12 weeks at 16 different psychiatric outpatient clinics throughout Pakistan, from September 2020 to November 2020. Method: The study included 498 individuals with serious depressive disorder diagnoses. The degree of depression symptoms and cognitive impairment was assessed. Psychiatrists gave trial participants vortioxetine after completing the Clinical Global Impression-Severity scale (CGI-S), the Patient Health Questionnaire-9 (PHQ-9), and the Perceived Deficits Questionnaire (PDQ). The variables were reassessed one week (+/- 3 days), one month (+/- 7 days), and three months (+/- 14 days) after the treatment began. Results: After completing a 12-week course of therapy with vortioxetine, mean PHQ 9 and PDQ scores of MDD individuals showed significant improvements. This indicates that vortioxetine is effective in reducing depression symptoms as well as cognitive impairments in MDD patients. A strong connection was seen between PHQ-9 and PDQ scores, indicating a direct relationship between cognitive impairment and depressed symptoms. Conclusions: The results of the research demonstrate how well vortioxetine works to treat cognitive impairments in MDD patients while also reducing depressed symptoms. These findings demonstrate the possibility of vortioxetine as a beneficial therapeutic option for those with MDD diagnoses who also have cognitive impairment. Additional investigation is required to validate these findings and assess their suitability for other demographics.

The trajectory of depressive symptoms over time and the presence of depressive symptoms at a single time point with the risk of dementia among US older adults: A national prospective cohort study.

This study aims to assess the association between trajectories of depressive symptoms and the risk of dementia, and to compare the predictive ability of trajectories using multiple data points with depressive symptoms at a single data point. We included 5306 older adults from the Health and Retirement Study. We assessed depressive symptoms using the Center for Epidemiology Depression Scale (CES-D), and identified its 8- year trajectories (2002-2010) using latent class trajectory modeling. We calculated hazard ratios (HR) using Cox proportional hazards models. The concordance index (C-index) was used to compare the discriminative power of the models. We identified two trajectories of depressive symptoms, characterized by maintaining low CES-D scores, and moderate starting scores that steadily increased throughout the follow-up period. During 40,199 person-years, compared to the low trajectory, the increasing trajectory of depressive symptoms was associated with a higher risk of dementia (HR = 1.35; 95% CI: 1.09-1.67) (C-index = 0.759). For every point increase in the degree of depressive symptoms (CES-D scores) in 2010, the risk of dementia increased by 7% (95% CI: 1.03-1.12) (C-index = 0.760). The presence of depressive symptoms (CES-D scores ≥3) in 2010 was not associated with an increased risk of dementia (HR = 1.18; 95% CI: 0.98-1.43) (C-index = 0.759). The C-index values of cox models showed similar discriminative power. The increasing trajectory of depressive symptoms at multiple data points and the degree of depressive symptoms at a single data point were associated with an increased risk of subsequent dementia among older adults.

Patient-reported outcomes provide evidence for increased depressive symptoms and increased mental impairment in giant cell arteritis.

The spectrum of giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) represents highly inflammatory rheumatic diseases. Patients mostly report severe physical impairment. Possible consequences for mental health have been scarcely studied. The aim of this study was to investigate psychological well-being in the context of GCA and PMR. Cross-sectional study with N = 100 patients with GCA and/or PMR (GCA-PMR). Patient-reported outcomes (PROs) were measured using the Short Form 36 Version 2 (SF-36v2) and visual analog scale (VAS) assessment. Moreover, the Patient Health Questionnaire 9 (PHQ-9) was used in 35 of 100 patients to detect depression. To compare PROs with physician assessment, VAS was also rated from physician perspective. To assess a possible association with inflammation itself, serological parameters of inflammation (C-reactive protein [CRP], erythrocyte sedimentation rate [ESR]) were included. In all scales of the SF-36v2 except General Health (GH) and in the physical and mental sum score (PCS, MCS), a significant impairment compared to the German reference collective was evident (MCS: d = 0.533, p < 0.001). In the PHQ-9 categorization, 14 of the 35 (40%) showed evidence of major depression disorder. VAS Patient correlated significantly with PHQ-9 and SF-36 in all categories, while VAS Physician showed only correlations to physical categories and not in the mental dimensions. Regarding inflammatory parameters, linear regression showed CRP to be a complementary significant positive predictor of mental health subscale score, independent of pain. PRO show a relevant impairment of mental health up to symptoms of major depression disorder. The degree of depressive symptoms is also distinctly associated with the serological inflammatory marker CRP.

Microbiota alteration of Chinese young male adults with high-status negative cognitive processing bias.

Evidence suggests that negative cognitive processing bias (NCPB) is a significant risk factor for depression. The microbiota-gut-brain axis has been proven to be a contributing factor to cognitive health and disease. However, the connection between microbiota and NCPB remains unknown. This study mainly sought to explore the key microbiota involved in NCPB and the possible pathways through which NCPB affects depressive symptoms. Data in our studies were collected from 735 Chinese young adults through a cross-sectional survey. Fecal samples were collected from 35 young adults with different levels of NCPB (18 individuals were recruited as the high-status NCPB group, and another 17 individuals were matched as the low-status NCPB group) and 60 with different degrees of depressive symptoms (27 individuals were recruited into the depressive symptom group, as D group, and 33 individuals were matched into the control group, as C group) and analyzed by the 16S ribosomal RNA sequencing technique. As a result, the level of NCPB correlated with the degree of depressive symptoms as well as anxiety symptoms and sleep quality (p < 0.01). The β-diversity of microbiota in young adults was proven to be significantly different between the high-status NCPB and the low-status NCPB groups. There were several significantly increased bacteria taxa, including Dorea, Christensenellaceae, Christe -senellaceae_R_7_group, Ruminococcaceae_NK4A214_group, Eggerthellaceae, Family-XIII, Family_XIII_AD3011_group, Faecalibaculum, and Oscillibacter. They were mainly involved in pathways including short-chain fatty acid (SCFA) metabolism. Among these variable bacteria taxa, Faecalibaculum was found associated with both NCPB and depressive symptoms. Furthermore, five pathways turned out to be significantly altered in both the high-status NCPB group and the depressive symptom group, including butanoate metabolism, glyoxylate and dicarboxylate metabolism, propanoate metabolism, phenylalanine, tyrosine, and tryptophan biosynthesis, valine, leucine, and isoleucine degradation. These pathways were related to SCFA metabolism. Fecal microbiota is altered in Chinese young male adults with high status NCPB and may be involved in the biochemical progress that influences depressive symptoms.

Adherence to Antiretroviral Treatment Among Adult HIV Patients in Addis Ababa, Ethiopia: A Facility-Based Cross-Sectional Study

Adherence to Antiretroviral Treatment (ART) has paramount significance to reduce HIV replication, warding off viral resistance, and decrease HIV – related morbidity and mortality. HIV patients have been challenged to attain the optimal level of adherence to ART owing to a variety of social, psychological, spiritual, and medical reasons.To examine factors associated with adherence among HIV patients taking antiretroviral treatment at five government hospitals in Addis Ababa, Ethiopia.A survey was conducted in ART clinics of five randomly selected hospitals in Addis Ababa from January 21, 2018 to February 25, 2018. Data collected using six standardized scales were entered and analyzed using SPSS version 20. Descriptive statistics was used to summarize socio-demographic information, estimate the prevalence of alcohol use, depression, and adherence to antiretroviral treatment. ANOVA and t tests were used to examine mean differences, and multiple regression was used to identify the contribution of the independent variables on the dependent variables at95% confidence Interval and a statistical significance p&lt; .001. Adult HIV patients consisting of 64% were fully adhered to ART, 52% reported current use of alcohol, and 55.6% reported having some degree of depressive symptoms. Alcohol use (𝛽= -.059), depressive symptoms (𝛽= -.022) and HIV disclosure stigma (𝛽= -.034) were associated with adherence. In conclusion, ART adherence was significantly associated with alcohol use, depressive symptoms and HIV disclosure stigma. Addressing psychosocial factors related to ART adherence would help Adult HIV patients to improve their level of adherence.

Level of depression and its associated factors among the frontline physicians of Bangladesh during the COVID-19 outbreak

The COVID-19 pandemic has exposed the frontline physicians to a greater risk of getting infected, tremendous workload, and drastic changes in their work environment, leading to an increased prevalence of depression among doctors from many countries, including Bangladesh. The aim of this study was to examine the association of various personal, professional and psychosocial factors with different degrees of depressive symptoms among the frontline doctors of Bangladesh working during the COVID-19 pandemic. An online, cross-sectional survey was conducted for that purpose and data were collected from 312 doctors working in Bangladeshi hospitals using a self-administered survey questionnaire inclusive of a validated tool (Patient Health Questionnaire-9). Among the participants, around half were of age 30-34 years (51.3%), 81.8% worked in public hospitals and 70.5% did not have any comorbidity. Regarding workplace conditions, 77% of the doctors reported a perceived shortage of healthcare providers at their workplace, while 95% reported a perceived shortage of equipment, most commonly N95 masks (49%), gowns (35%), eye-protective shields (35%). A total of 199 (63.8%) participants received formal training since the beginning of the pandemic. According to the response from PHQ-9 questionnaire, 17 (5%) participants reported having no depression, while 18 (6%), 18 (6%), 25 (8%), and 234 (75%) reported having mild, moderate, moderately severe, and severe depression. Findings from multiple logistic regression showed the odds of moderate-to-severe depression to be higher among physicians with comorbidities (OR:7.47, CI: 1.27-43.89, P: 0.026) and those who felt extremely worried from looking at negative news on social/mass media (aOR: 15.180, CI:1.98-116.683, P: 0.009). To preserve and promote the psychological well-being of Bangladeshi doctors, it is, therefore, crucial to take these identified sources and risk factors of depression under sincere consideration by the responsible authorities and appropriate measures should be designed to remove these sources of depression to better support the physicians of the country.

Sleep quality status, anxiety, and depression status of nurses in infectious disease department.

ObjectiveTo investigate the current status of sleep quality and influencing factors of clinical nurses in infectious disease hospitals, and to provide basis and reference for improving their sleep status and providing psychological support.MethodsUsing convenience sampling method, clinical nurses from a tertiary hospital for infectious diseases were selected as the survey subjects in September 2021. General information questionnaire, Pittsburgh Sleep Quality Questionnaire (PSQI), Generalized Anxiety Disorder Scale (GAD-7), Depression Screening Scale (PHQ-9) were used for questionnaire surveys, and multiple linear regression was used to analyze the impact of decreased sleep quality in clinical nurses factor.ResultsA total of 460 questionnaires were returned, of which 442 were valid, effective rate is 96.09%. The Pittsburgh sleep quality index (PSQI) score of 442 clinical nurses was 7.07 ± 2.14, of which 60 (13.57%) had sleep disorders; the Generalized Anxiety Disorder Scale (GAD-7) score was 4.77 ± 3.50, of which 182 (41.18%) had varying degrees of anxiety; The score of PHQ-9 was 5.95 ± 3.79, of which 187 (42.31%) had different degrees of depressive symptoms. The stepwise multiple linear regression analysis which involved PHQ-9 and GAD-7 scores showed that: both the PHQ-9 score and the GAD-7 score were positively correlated with the sleep quality score, and the PHQ-9 score increased every time 1 point, sleep quality score increased by 0.239 points; GAD-7 score increased by 1 point, sleep quality score increased by 0.150 points. The overall model test (F = 109.760, P < 0.001) regression model is meaningful.ConclusionDecreased sleep quality is common among clinical nurses in infectious disease hospitals, and the sleep status of nurses is positively correlated with anxiety and depression. Nursing managers pay attention to sleep quality of clinical nurses in infectious disease hospitals and carry out effective interventions to improve the sleep quality of nurses.

Characterizing the longitudinal course of symptoms and functioning in bipolar disorder.

The course of Bipolar Disorder (BD) is highly variable, with marked inter and intra-individual differences in symptoms and functioning. In this study, we identified illness trajectories across major clinical domains that could have etiological, prognostic, and therapeutic relevance. Using the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) study, we performed univariate and multivariate trajectory modeling of depressive symptoms, manic symptoms, and psychosocial functioning. Multinomial regression was performed to identify baseline variables associated with poor outcome trajectories. Depressive symptoms predominated, with most subjects being found in trajectories characterized by various degrees of depressive symptoms and 13% of subjects being classified in a poor outcome 'persistently depressed' trajectory. Most subjects experienced few manic symptoms, although approximately 10% of subjects followed a trajectory of persistently manic symptoms. Trajectory analysis of psychosocial functioning showed impairment in most of the sample, with little improvement during follow up. Multi-trajectory analyses highlighted significant impairment in subjects with persistently mixed and persistently depressed trajectories of illness. In general, poor outcome trajectories were marked by lower educational attainment, higher unemployment and disability, and a greater likelihood of adverse clinical features (rapid cycling and suicide attempts) and comorbid diagnoses (anxiety disorders, PTSD, and substance abuse/dependence disorders). Subjects with BD can be classified into several trajectories of clinically relevant domains that are prognostically relevant and show differing degrees of associations with a broad range of negative clinical risk factors. The highest level of psychosocial disability was found in subjects with chronic mixed and depressive symptoms, who show limited improvement despite guideline-based treatment.

Parental care and depressive symptoms among Chinese medical students: roles of empathy and gender

BackgroundMedical students in China who face the dual pressure of study and employment tend to experience subclinical depressive symptoms. Parental care plays an important direct and indirect role in the psychological development of medical students, and the extent and mechanism of this role urgently need to be studied and discussed.MethodsAfter simple random sampling and screening of valid questionnaires, data from a total of 924 people were used. The participants completed the parental bonding instrument, self-rating depression scale, Chinese version of the Jefferson empathy scale-medical student edition and self-rating anxiety scale to evaluate parental care, empathy, depressive symptoms and anxiety. The data were statistically processed using a descriptive analysis, correlation analysis and test of moderated mediation.ResultsMaternal care had a significant negative predictive effect on depressive symptoms among medical students. Strong maternal care can reduce the occurrence of depressive symptoms in medical students. Empathy played a positive mediating role such that both types of empathy could alleviate the effect of weak maternal care on the depressive symptoms of medical students. However, neither cognitive empathy nor affective empathy played a mediating role in the relationship between paternal care and depressive symptoms. Nevertheless, the relationship between maternal care and empathy was moderated by the medical students’ gender.ConclusionsThe effect of this relationship on female medical students deserves special attention. The results of this study provide a reference and basis for the adjustment of medical education. This study could also help in the design of effective psychological intervention measures to reduce the degree of depressive symptoms and enhance personal empathy.

Psychophysiological effects of rhythmic music combined with aerobic exercise in college students with minimal depressive symptoms

Mental health problems are common during the transition from adolescence to young adulthood. Previous studies reported that rhythmic music plus aerobic exercise can have a beneficial effect on emotional state. We examined whether the beneficial effect differed between aerobic exercise interventions with or without rhythmic music. A sample of 94 college students who either had no depressive symptoms (n ​= ​47) or minimal depressive symptoms (n ​= ​47) underwent 30-min interventions in a randomized and counterbalanced order: rest, rhythmic music, aerobic exercise and aerobic exercise plus rhythmic music. Response time and accuracy of selective attention to positive and negative images were recorded using the spatial cueing paradigm. Participants’ heart rate during all conditions and perceived exertion after each condition were measured to clarify physiological and perceptual responses, respectively. The results revealed that a multimodal intervention combining aerobic exercise and rhythmic music had a significant facilitatory effect on attentional bias to positive emotional cues in minimal depressive participants (t ​= ​−2.336, p ​= ​0.024), including less perceived exertion and higher heart rate after/during the intervention process. The single-modality intervention of aerobic exercise had significant positive effects for individuals with no depressive symptoms (t ​= ​−2.510, p ​= ​0.016). The multimodal intervention was more effective than the single-modality intervention for individuals with minimal depressive symptoms, but the single-modality aerobic exercise intervention was more effective for individuals with no depressive symptoms, providing new evidence for the specificity of the intervention effect for people with different degrees of depressive symptoms.

Severity of depressive symptomatology and socio-demographic characteristics of patients with alcoholism in the Republic of Dagestan depending on territorial patterns of residence

Introduction. Living in urban and rural areas can affect the risk of developing and the course of alcohol dependence and comorbid conditions. The aim of the work was to evaluate the degree of depressive symptoms and socio-demographic characteristics of patients with alcoholism in the Republic of Dagestan, depending on the territorial features of residence. Materials and methods. The study involved 104 patients aged 51.2±9.9 years (27 to 74 years), registered in the State Budgetary Institution «Republican narcological dispensary» of the Republic of Dagestan with a diagnosis of alcohol dependence. The patients were divided into 2 groups depending on the territorial features of their residence: 62 (59.6%) patients residing in urban areas and 42 (40.4%) residing in rural areas. In order to evaluate socio-demographic characteristics all patients were questioned. The degree of severity of depressive symptoms was assessed with the Beck scale. Results. Analysis of alcohol dependence characteristics revealed no differences between the groups (p&gt;0.05). The degree of depression was found to be more pronounced in patients living in rural areas than in those living in urban areas: mild depression was 7.3% and 29.0% (p&lt;0.05), moderate depression was 9.8% and 1.6% (p&lt;0.05), and severe depression was 39.0% and 25.8% (p&lt;0.05), respectively. The severity of depression correlated with the presence of work in patients (r=0.324; p&lt;0.001). Discussion. Alcohol consumption leads to a more severe manifestation of depression, contributing to physiological changes in the body. Conversely, depressed people are more prone to uncontrolled alcohol consumption, which in their subjective opinion alleviates psychosocial suffering. The connection between alcohol abuse and depressive symptoms is bidirectional, meaning that both of these disorders influence the development and course of the other and simultaneously exacerbate the risk of developing the other disorder. Conclusions. Alcohol-dependent individuals living in rural areas of the Republic of Dagestan are characterized by unemployment that correlates with anxiety-depressive symptoms, as well as a more severe degree of depression severity.

Hubungan Intensitas Penggunaan Media Sosial dengan Gejala Depresi pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen

ABSTRACT&#x0D; Background: Social media is an inseparable component of human life, included medical students. Social media usage has both positive and negative benefits. Several studies showed excessive use of social media can cause mental health problems, such us depression. This study aims to evaluated the correlation between the intensity of social media use and the degree of depressive symptoms in students of the Faculty of Medicine, University of HKBP Nommensen.&#x0D; Methods: Analytical observational study with cross-sectional design was conducted on 101 students of the Faculty of Medicine, University of HKBP Nommensen using questionnaires such us Social Networking Time Use Scale (SONTUS) to measure the intensity of social media use, and Beck Depression Inventory-II (BDI-II) to assess the degree of depressive symptoms. Data analysis were done by using the Spearman's rank correlation coefficient test.&#x0D; Results: This study showed that 38.6% respondents had low intensity, 41.6% medium intensity, and 19.8% respondents had high intensity of social media usage. There were 81.2% of respondent had no depression, 10.9% had mild depression, 5.9% moderate depression, and 2.0% severe depression. The Spearman test results showed that there is no correlation between the intensity of social media usage and the degree of depressive symptoms (p&#x0D; = 0.882) with a very weak correlation value (r = 0.015).&#x0D; Conclusion: There is no correlation between the intensity of social media use and the degree of depressive symptoms in the Faculty of Medicine, University of HKBP Nommensen students.&#x0D; Keywords: Social media, depression, medical students.

Depressive symptoms and suicidality by menopausal stages among middle-aged Korean women.

There has been increasing evidence of hormonal changes during reproductive events that lead to mood changes. However, studies on the severity of psychological problems according to the menopausal stage are limited. Thus, this study aimed to investigate the association between menopausal stages, depression and suicidality. A total of 45 177 women who underwent regular health check-ups between 2015 and 2018 at Kangbuk Samsung Hospital were included. Participants were stratified into four groups (pre-menopause, early transition, late transition and post-menopause) based on the Stages of Reproductive Aging Workshop Criteria. The Center for Epidemiological Studies-Depression scale (CESD) was used to evaluate depressive symptoms, and the degree of depressive symptoms was classified as moderate (CESD score 16-24) or severe (CESD score ⩾ 25). To measure suicide risk, we administered questionnaires related to suicidal ideation. Overall, the prevalence of CESD scores of 16-24 and ⩾ 25 was 7.6 and 2.8%, respectively. Menopausal stages were positively associated with depressive symptoms in a dose-dependent manner. Multivariable-adjusted prevalence ratios (PRs, 95% confidence intervals) for CESD scores of 16-24 comparing the stages of the early menopausal transition (MT), late MT and post-menopause to pre-menopause was 1.28 (1.16-1.42), 1.21 (1.05-1.38) and 1.58 (1.36-1.84), respectively. The multivariable-adjusted PRs for CESD scores ⩾ 25 comparing the stages of the early MT, late MT and post-menopause to pre-menopause were 1.31 (1.11-1.55), 1.39 (1.12-1.72), 1.86 (1.47-2.37), respectively. In addition, the multivariable-adjusted PRs for suicidal ideation comparing the early MT, late MT and post-menopause stages to the pre-menopause stage were 1.24 (1.12-1.38), 1.07 (0.93-1.24) and 1.46 (1.25-1.70) (p for trend <0.001), respectively. These findings indicate that the prevalence of depressive symptoms and suicidal ideation increases with advancing menopausal stage, even pre-menopause.

C-Reactive Protein Levels and Gadolinium-Enhancing Lesions Are Associated With the Degree of Depressive Symptoms in Newly Diagnosed Multiple Sclerosis.

Background: Inflammation is essential for the pathogenesis of multiple sclerosis (MS). While the immune system contribution to the development of neurological symptoms has been intensively studied, inflammatory biomarkers for mental symptoms such as depression are poorly understood in the context of MS. Here, we test if depression correlates with peripheral and central inflammation markers in MS patients as soon as the diagnosis is established.Methods: Forty-four patients were newly diagnosed with relapsing-remitting MS, primary progressive MS or clinically isolated syndrome. Age, gender, EDSS, C-reactive protein (CRP), albumin, white blood cells count in cerebrospinal fluid (CSF WBC), presence of gadolinium enhanced lesions (GE) on T1-weighted images and total number of typical MS lesion locations were included in linear regression models to predict Beck Depression Inventory (BDI) score and the depression dimension of the Symptoms Checklist 90-Revised (SCL90RD).Results: CRP elevation and GE predicted significantly BDI (CRP: p = 0.007; GE: p = 0.019) and SCL90RD (CRP: p = 0.004; GE: p = 0.049). The combination of both factors resulted in more pronounced depressive symptoms (p = 0.04). CSF WBC and EDSS as well as the other variables were not correlated with depressive symptoms.Conclusions: CRP elevation and GE are associated with depressive symptoms in newly diagnosed MS patients. These markers can be used to identify MS patients exhibiting a high risk for the development of depressive symptoms in early phases of the disease.

Locus of Control and Its Associations with Depressive Symptoms amongst People with Dementia

Introduction: Depression is common amongst people with dementia. This study examines whether locus of control (LoC), a perceived control construct influential in the coping process, is related to depressive symptoms in this population. Methods: In this prospective observational study, 257 community-dwelling older adults with a confirmed dementia diagnosis were included. At baseline, measures of depressive symptoms, LoC, cognition, independent functional ability, general health, dementia severity, and dementia disease insight were collected. At follow-up, measures of depressive symptoms and cognition were collected. Multiple linear regression using degree of depressive symptoms as measured with Montgomery-Asberg Depression Rating Scale as a dependent variable was applied to assess whether LoC was associated with depressive symptoms at baseline and follow-up while controlling for covariates. Results: LoC (p < 0.001), general health (p = 0.003), and insight (p = 0.010) were associated with severity of depressive symptoms at baseline, accounting for 28% of the variance. LoC (p = 0.025) and depressive symptoms (p < 0.001) at baseline were associated with severity of depressive symptoms at follow-up, accounting for 56.3% of the variance. Conclusion: LoC was significantly associated with severity of depressive symptoms in people with dementia at baseline and at follow-up. Attention to LoC may be valuable for our understanding of depression in people with dementia, and interventions targeting depression could benefit from including a focus on internalizing perceived control. However, these findings are novel, and more research is needed.

Effect of COVID-19 Quarantine on the Sleep Quality and the Depressive Symptom Levels of University Students in Jordan During the Spring of 2020.

Objectives: This study was designed to assess the effect of COVID-19 home quarantine and its lifestyle challenges on the sleep quality and mental health of a large sample of undergraduate University students in Jordan. It is the first study applied to the Jordanian population. The aim was to investigate how quarantine for several weeks changed the students' habits and affected their mental health.Methods: A cross-sectional study was conducted using a random representative sample of 6,157 undergraduate students (mean age 19.79 ± 1.67 years, males 28.7%) from the University of Jordan through voluntarily filling an online questionnaire. The Pittsburgh Sleep Quality Index (PSQI) and the Center for Epidemiologic Studies-Depression Scale (CES-D) were used to assess sleep quality and depressive symptoms, respectively.Results: The PSQI mean score for the study participants was 8.1 ± 3.6. The sleep quality of three-quarters of the participants was negatively affected by the extended quarantine. Nearly half of the participants reported poor sleep quality. The prevalence of poor sleep quality among participants was 76% (males: 71.5% and females: 77.8%). Similarly, the prevalence of the depressive symptoms was 71% (34% for moderate and 37% for high depressive symptoms), with females showing higher prevalence than males. The overall mean CES-D score for the group with low depressive symptoms is 9.3, for the moderate group is 19.8, while it is 34.3 for the high depressive symptoms group. More than half of the students (62.5%) reported that the quarantine had a negative effect on their mental health. Finally, females, smokers, and students with decreased income levels during the extended quarantine were the common exposures that are significantly associated with a higher risk of developing sleep disturbances and depressive symptoms.Conclusions: Mass and extended quarantine succeeded in controlling the spread of the COVID-19 virus; however, it comes with a high cost of potential psychological impacts. Most of the students reported that they suffer from sleeping disorders and had a degree of depressive symptoms. Officials should provide psychological support and clear guidance to help the general public to reduce these potential effects and overcome the quarantine period with minimum negative impacts.

Quality of life in isolated dystonia: non-motor manifestations matter

ObjectiveTo evaluate the relationship between health-related quality of life (HR-QoL) and both physical and psychiatric factors in a large, international, multicentre cohort of patients with isolated dystonia, the Dystonia Coalition.MethodsNatural...

Main and Moderating Influence of Five-Factor Model Traits on the Association between Intimate Partner Violence and Depressive Symptoms

ABSTRACT Intimate partner violence (IPV) is a common problem for young adult women and is associated with symptoms of depression. However, not all women who experience IPV exhibit depressive symptoms. Research suggests that one factor that influences women’s degree of depressive symptoms in the aftermath of IPV is personality, but different studies have emphasized different aspects of personality (e.g., affective vs. interpersonal). The Five-Factor Model of personality (FFM) provides a framework for integrating different models of personality traits, although research on FFM traits in the context of IPV has thus far been limited. In this study, we examine the main and moderating effects of FFM traits on the association between IPV and depressive symptoms in a sample of young adult women (N = 565) using a Bayesian approach to multiple regression. Results suggested strong effects of two of the five FFM traits: Neuroticism exacerbated and Extraversion buffered the effect of IPV on depressive symptoms. These findings contribute to our understanding of vulnerability and resilience to women’s mental health in the context of IPV and provide directions for future research and clinical intervention.

Direct Relationship Between Sleep Disorder and Depression Severity in Iranian Adolescents

Background: Sleep pattern is one of the most important issues which can affect mental development in adolescents. Objectives: This study was designed to asses sleep pattern and its relationship with depression in order to obtain information for planning interventional programs and health promotion in adolescents. Methods: This was a cross-sectional study conducted on high school students in Hamadan, Iran in 2019. Mean age of the students was 16.53 ± 0.69 years (Min - Max: 15 - 19), and 290 (50.3%) students were girls. Samples were selected by multiple cluster sampling method in which 576 students were enrolled in the study. Two standard, valid and reliable self-reported questionnaire was used for recording sleep pattern (PSQ) and depression (Beck). After data collection, SPSS was used for data analysis. All P values less than 0.05 were considered as significant. Results: Nearly 70% of the adolescents had problems in some subscales of sleep disorder included in mental quality of sleep, delay in falling asleep and daily dysfunction. Among them in 10% sleep duration was less than 5 hours and in 69% usual bedtime was after midnight (24 o’clock). Severe sleep problem in boys and students with fine educational status was more than others (P value &lt; 0.001) and there was a statically significant correlation between sleep disorder and depression score (Pearson correlation: r = 0.42; P &lt; 0.001) and in students with severe sleep disorder, 48.9% were severely depressed. Conclusions: Problems in mental quality of sleep was notable in Iranian adolescents, almost half of them had some degree of depression symptoms. Being boy and having severe problem in sleep pattern were predictors for depression. This information might be applied for well-being as well as physical and mental development interventional programs such as sleep health screening and adolescents and their parents’ educational programs in adolescents’ health promotion sector.

Frecuencia de depresión e incontinencia urinaria en pacientes de una institución de alta complejidad en Callao, Perú

Introducción: El objetivo fue explorar la frecuencia y asociación entre la presencia de síntomas depresivos con la existencia de síntomas sugestivos de incontinencia urinaria en un grupo de mujeres atendidas en un hospital público del Perú. Material y Métodos: Estudio transversal realizado en mujeres con Seguro Integral de Salud que acudieron al consultorio de ginecología del hospital público de alta complejidad Hospital Nacional Daniel Alcides Carrión durante noviembre y diciembre del 2018. Se calculó una muestra con Epidat versión 3.1 y se seleccionó a las participantes por conveniencia. Las principales variables de interés fueron incontinencia urinaria y depresión, ambas medidas mediante instrumentos de medición validados: ICIQ-SF y escala de autoevaluación para la depresión de Zung, respectivamente. Para explorar la asociación se usó exacta de Fisher y Kruskall-Wallis. Resultados: Se estudió a 186 mujeres con edades entre 40 y 60 años. Un total de 176 mujeres (94,6 %) se definieron como incontinentes y 183 con depresión (98,4 %). No se encontró asociación entre los síntomas depresivos con los síntomas sugestivos de incontinencia urinaria (p&gt;0,05), pero sí en el grado de síntomas depresivos con el puntaje de incontinencia (p=0,0001). Conclusiones: Una proporción considerable de mujeres padece de síntomas depresivos y de incontinencia urinaria. Por otra para, parece existir una posible asociación entre los puntajes de incontinencia urinaria y la severidad de los síntomas depresivos. Se requieren más estudios que exploren esta posible asociación para dilucidar el impacto potencial que la incontinencia urinaria posee sobre el estado anímico de las mujeres en Perú.