Deep Pressure Research Articles

A Compressive Armchair (OTO) to Perform Deep Pressure Therapy in Children With Autism Spectrum Disorder: User-Centered Design and Feasibility Study.

Deep pressure therapy (DPT) is widely used to reduce anxiety in children with autism spectrum disorder (ASD), but evidence of its efficacy is limited. This study aims to design a usable, nonstigmatizing compressive armchair that can be easily controlled, electronically, by the user. A user-centered approach was used to assess the usability of the device. Testing was carried out in a day hospital for children with ASD in France, with a convenience sample of children with severe forms of ASD and intellectual deficiency (N=39). The Witteman design guideline was used. The System Usability Scale and time of use were reported. The final product is a compressive armchair designed to be user centered, with 4 different cells that can be inflated to induce tailored pressure on the body. The pressure level is recorded electronically. Usability was between good and excellent. The device was used by 39 children, once or twice weekly, over a period of 31 months. Each session lasted between 3 and 20 minutes. The armchair takes up less space than a hug machine. Performing sessions with the chair is feasible. First clinical impressions show a decrease in anxiety, improved emotional regulation, and improved attention. DPT is widely used in occupational therapy and frequently requested by parents, but efficacy studies are too scarce to make evidence-based recommendations for its use. The results presented here support further controlled efficacy studies of DPT in the treatment of anxiety in children with ASD.

Weighted Vest Combined With Vibrotactile Stimulations Decrease the Sympathetic Activity: A Repeated Measures Study

ABSTRACTBackground and AimsMental and neurological disorders are a growing global concern, further intensified by the COVID‐19 pandemic. Stress management techniques, such as deep pressure therapy, have gained attention, with weighted vests commonly used for anxiety relief. However, there is limited scientific evidence supporting their efficacy. This study aimed to rigorously assess the effectiveness of a weighted vest incorporating vibrotactile stimulation in reducing anxiety by measuring physiological indicators—pulse rate and skin conductance (SC)—as well as subjective comfort ratings.MethodsA total of 30 final‐semester college students participated in the study. Participants wore a vibrotactile‐weighted vest, and both pulse rate and skin conductance (SC) were measured to gauge anxiety levels. Additionally, participants rated their comfort using a Comfort Rating Scale (CRS). Changes in pulse rate and SC were statistically analyzed, and effect sizes (Cohen's d) were calculated to assess the magnitude of the intervention's impact.ResultsThe weighted vest with vibrotactile stimulation resulted in a significant reduction in both pulse rate (dpulse = 0.23–0.62) and SC (dsc = 0.32–0.66), indicating a small to medium effect size in anxiety reduction. Subjective evaluations of the vest using the CRS revealed low scores on discomfort‐related items, with participants rating unfavorable statements between 1.5/10 and 4.6/10, suggesting overall comfort during use.ConclusionThis study provides compelling evidence that vibrotactile‐weighted vests effectively reduce anxiety, as indicated by both physiological measures and subjective comfort ratings. The findings support the potential of this intervention as a formal therapeutic tool for stress and anxiety reduction. Further research may explore long‐term effects and broader applications in clinical settings.

Deep Kinetic Energy Response to the Variability of the Kuroshio Extension

AbstractThe transfer of energy from the upper to deep oceans is a well‐known and challenging subject in physical oceanography. This research investigates the intricate relationship between surface and deep ocean currents. Utilizing nearly 2 years of observations from the Kuroshio Extension System Study (KESS), our study unveils the deep‐ocean kinetic energy response to the Kuroshio Extension (KE) variability. We introduce the Kuroshio Extension Jet Path Index (KEJPI), which identifies two distinct modes of the KE jet on an intra‐seasonal timescale. Our findings reveal a strong correlation (0.73) between KEJPI and the mean kinetic energy of deep‐ocean geostrophic circulation, suggesting that the KE jet's large amplitude meanders have a significant impact on deep‐ocean kinetic energy. Singular Value Decomposition (SVD) analysis further unveils a co‐evolving spatial pattern between upper and lower ocean kinetic energy. We investigate the dynamic vertical coupling (DVC) mechanism by examining the coherent variation among the sea surface height (SSH), 15°C isotherm (Z15), deep pressure anomaly, and abyssal flow. The KE jet migration can induce net divergence and convergence within the water column, which in turn generates deep‐ocean quasi‐geostrophic currents. These currents show a marked increase in kinetic energy, reaching levels three times higher than the background. This DVC‐driven kinetic energy can further cascade into near‐inertial and high‐frequency internal waves, contributing to abyssal mixing. Our study underscores the role of large current system instabilities in transferring energy to the deep ocean and facilitating deep mixing processes.

Exploring surface integrity: Experimental investigation into abrasive waterjet deep hole drilling on ss 316L for biomedical applications

Precision drilling of difficult-to-cut materials with exceptional surface integrity is a crucial factor in producing advanced manufactured components in industries like aviation, automotive, defense, electronic, and medical devices. More specifically, deep hole drilling enables precise customization of prostheses, improving patient comfort and functionality. Abrasive waterjet deep hole drilling has become a vital drilling technique in many industries due to its adaptability and effectiveness in drilling intricate shapes on hard-to-cut materials. The interplay between process parameters and surface finish underscores the need for systematic investigation to enhance drilling efficiency and quality. In this research, an attempt has been made to explore the influence of abrasive waterjet deep hole process parameters viz water pressure and standoff distance on the surface integrity of the drilled holes for biomedical applications. A surface roughness tester has been used to evaluate surface roughness at three distinctive places, namely the top, middle, and bottom of the drilled holes. The investigation showed that surface roughness at the top of the holes is less as compared to the middle and bottom of the holes. The average surface roughness along the depth of the drilled holes is greatly influenced by water pressure. Additionally, the morphology of the drilled holes has been studied using a scanning electron microscope (SEM). SEM images revealed that the top surface of the drilled holes is free from defects.

Relationship between sensory processing skills and motor skills in 12-month-old infants.

Identifying sensory processing problems of 12-month-old preterm and term children and defining their relationship with motor skills are essential for appropriate interventions and optimal sensory-motor development. This study aimed to determine sensory processing difficulties in 12-month-old babies and examine their relationship with motor skills. This cross-sectional study included 61 infants (28 preterm and 33 full-term, ages 12 months). The infants' sensory processing skills were evaluated using the Test of Sensory Functions in Infants (TSFI), and their gross and fine motor skills were assessed with the Peabody Developmental Motor Scales-2 (PDMS-2). Sensory processing difficulties were more common in preterm babies. Multiple linear regression models indicated a significant positive association between PDMS-2 gross/fine motor scores and TFSI total scores, reactivity to tactile deep pressure, and ocular-motor control in the total sample. Furthermore, there was a relationship between gross motor and adaptive motor function, and fine motor scores were found to be associated with visual-tactile integration sensory scores. Preterm babies are more likely than their full-term peers to have sensory processing problems around the age of one, which can affect their motor skills. The results support the relationship between children's sensory and motor processing skills. Practitioners such as occupational and physical therapists should be alert to this relationship in infants with sensory processing and motor problems. Taking this relationship into consideration when planning intervention programs can be a guide for an effective intervention.

Nurse understaffing associated with adverse outcomes for surgical admissions.

Nurses play a crucial role in maintaining the safety of surgical patients. Few nurse staffing studies have looked specifically at surgical patients to examine the impact of exposure to low staffing on patient outcomes. A longitudinal patient analysis was conducted in four organizations in England using routine data from 213 910 admissions to all surgical specialties. Patients' staffing exposures were modelled as counts of understaffed registered nurse and nurse assistant days in the first 5 inpatient days. Understaffing was identified when staffing per patient-day was below the mean for the ward. Cox models were used to examine mortality within 30 days of admission and readmission within 30 days of discharge. Generalized linear models were used to investigate duration of hospital stay and occurrence of hospital-acquired conditions. Increased exposure to registered nurse understaffing was associated with longer hospital stay and increased risk of deep vein thrombosis, pneumonia, and pressure ulcers. This was also true for nurse assistant understaffing, but the effect sizes tended to be smaller. In the Cox models, there were similarly increased hazards of death for registered nurse understaffing (HR 1.09, 95% c.i. 1.07 to 1.12) and nurse assistant understaffing (HR 1.10, 1.08 to 1.13), whereas the effect size of registered nurse understaffing for readmission (HR 1.02, 1.02 to 1.03) was greater than that seen with nurse assistants (HR 1.01, 1.01 to 1.02). Understaffing by both registered nurses and nursing assistants is associated with increased risks of a range of adverse events, and generally larger effects are seen with registered nurse understaffing.

Upper Bound Limit Analysis of Deep Tunnel Face Support Pressure with Nonlinear Failure Criterion under Pore Water Conditions

Based on the nonlinear failure criterion and modified tangential technique, the upper bound solutions of the critical supporting pressure on the deep tunnel face were obtained under pore water pressure conditions. The influence of parameters on the critical supporting pressure and collapse range was investigated according to the unlimited block failure mechanism. It was found that the upper bound solutions of the critical supporting pressure increase with the growth of the nonlinear coefficient and pore water pressure coefficient. The collapse range of the tunnel face scales out with the increase in the nonlinear coefficient and shrinks with an increasing pore water pressure coefficient. Moreover, with the increase in the nonlinear coefficient, the impact strength on critical supporting pressure and collapse range declines gradually. According to the calculated results, both the pore water pressure and nonlinear criterion factors have negative impacts on the stability of the tunnel face. Thus, more attention should be paid to these parameters to ensure face stability in deep tunnel construction.

Exploratory Study of Biomechanical Properties and Pain Sensitivity at Back-Shu Points.

Hypersensitive acupoints in specific body areas are associated with corresponding internal or visceral disorders. Back-shu points are clinically significant for the diagnosis of visceral organ disease, according to the biomechanical characteristics of the acupoints. In this study, we assessed the biomechanical characteristics and pain sensitivities of five back-shu points linked to five visceral organs in healthy participants. The study included 48 volunteer participants. A myotonometry was used to assess muscle tone and muscle stiffness at five back-shu points associated with visceral organs. Pressure was monitored using a microcontroller and a force sensor. Pain sensitivity was assessed in response to deep pressure pain produced by a constant force. Substantial differences in muscle tone and stiffness were observed at the five back-shu points; muscle tone was highest at BL15, whereas muscle tone and muscle stiffness were lowest at BL23. Moreover, pain sensitivity was significantly different among the acupoints; pain sensitivity was highest at BL23. There was a significant negative correlation between muscle tone and pain sensitivity. We found significant differences in muscle tone, muscle stiffness, and pain sensitivity among five back-shu points associated with visceral organs, which may be attributable to anatomical variations at each point. Our findings suggest that differences at back-shu points should be considered to ensure the accurate diagnosis of visceral disease.

Diagnosis of Pressure Ulcer Stage Using On-Device AI

Pressure ulcers are serious healthcare concerns, especially for the elderly with reduced mobility. Severe pressure ulcers are accompanied by pain, degrading patients’ quality of life. Thus, speedy and accurate detection and classification of pressure ulcers are vital for timely treatment. The conventional visual examination method requires professional expertise for diagnosing pressure ulcer severity but it is difficult for the lay carer in domiciliary settings. In this study, we present a mobile healthcare platform incorporated with a light-weight deep learning model to exactly detect pressure ulcer regions and classify pressure ulcers into six severities such as stage 1–4, deep tissue pressure injury, and unstageable. YOLOv8 models were trained and tested using 2800 annotated pressure ulcer images. Among the five tested YOLOv8 models, the YOLOv8m model exhibited promising detection performance with overall classification accuracy of 84.6% and a mAP@50 value of 90.8%. The mobile application (app) was also developed applying the trained YOLOv8m model. The mobile app returned the diagnostic result within a short time (≒3 s). Accordingly, the proposed on-device AI app can contribute to early diagnosis and systematic management of pressure ulcers.

Feasibility of Using Somatosensory Input on Pediatric Patient Anxiety & Experience in the Dental Clinic

Abstract Date Presented 03/23/24 Dental anxiety can lead to avoidance of dental care, causing deterioration of dental health in the long run. This study explores the use of somatosensory input (deep pressure and vibration) to reduce dental anxiety in a pediatric dental clinic. Primary Author and Speaker: Mahira Ali Additional Authors and Speakers: Virginia W. Chu Contributing Authors: Liara Vinson, Jayakumar Jayaraman, Carol Caudill

Comfort evaluation and physiological effects/autonomic nervous system response of inflatable deep pressure vest in reducing anxiety

BackgroundDeep pressure therapy treats anxiety by triggering physiological responses and promoting calmness. Moreover, measuring user comfort can improve product quality. ObjectiveTo investigate the physiological effects and subjective comfort level of inflatable deep pressure vests to enhance their calming effect. MethodsExperimental research was conducted with a one-group pretest-posttest design for physiological effects using pulse oximetry for peripheral pulse rate and a one-shot case study for three subscale parameters that help evaluate comfort (pressure, touch, and mobility) using the Numerical Rating Scale (NRS). Deep pressure intervention using the Inflatable Vest was performed for three sessions, each lasting 5 min. ResultsThis study was conducted with 46 participants (24 males, 22 females) aged 17–20 (19.52 ± 0.78). Although pulse rate consistently decreased in all sessions, session 1 showed a significant decrease (p = 0.014*, d = 0.379), whereas sessions 2 (p = 0.274, d = 0.163) and 3 (p = 0.597, d = 0.078) demonstrated non-significant decreases with small effect sizes. The pressure comfort subscale showed that 87.0 %, 4.3 %, and 8.7 % of the participants, and the touch comfort subscale test revealed that 82.6 %, 8.7 %, and 73.9 % of the participants rated it as comfortable, very comfortable, and less comfortable, respectively. The mobility subscale test showed that 73.9 % of the participants rated no limitation, 17.4 % rated somewhat limited, and only 8.7 % rated limitation. Decreased pulse rate and pressure comfort were significantly positively correlated (r = 0.282**, p < 0.01), whereas touch pressure and mobility were not (r = 0.160, p > 0.05; and r = 0.121, p > 0.05, respectively). Decreased pulse rate was also positively correlated with the overall score for the three aspects (r = 0.201*, p < 0.05) ConclusionsA comfortable inflatable deep pressure vest provides a physiologically calming effect for therapeutic modalities.

Probability analysis method for well kick under uncertain formation pressure conditions

Drilling safety and efficiency are greatly impacted by kick, a major problem that is hard to diagnose, assess, and predict due to the complexity and high uncertainty of the deep water drilling formation pressure system. This article forms a pre-drilling well kick probability prediction method by establishing a calculation model for wellbore ECD and using the numerical solution method of Monte Carlo simulation algorithm. The bottomhole pressure uncertainty range gradually increases with well depth, according to simulation calculations, and the probability of a well kick decreases with drilling fluid volume. Theoretically, safe well control in deepwater drilling can be guided by the well-established kick diagnosis and formation pressure assessment techniques.

The JWST weather report from the nearest brown dwarfs I: multiperiod JWST NIRSpec + MIRI monitoring of the benchmark binary brown dwarf WISE 1049AB

ABSTRACT We report results from 8 h of JWST/MIRI low resolution spectroscopic (LRS) monitoring directly followed by 7 h of JWST/NIRSpec prism spectroscopic monitoring of the benchmark binary brown dwarf WISE 1049AB, the closest, brightest brown dwarfs known. We find water, methane, and CO absorption features in both components, including the 3.3 μm methane absorption feature and a tentative detection of small grain ($\lt $ 1μm) silicate absorption at $\gt $8.5 μm in WISE 1049A. Both components vary significantly ($\gt 1~{{\rm per\ cent}}$), with WISE 1049B displaying larger variations than WISE 1049A. Using K-means clustering, we find three main transition points in wavelength for both components of the binary: (1) change in behaviour at $\sim$2.3 μm coincident with a CO absorption bandhead, (2) change in behaviour at 4.2 μm, close to the CO fundamental band at $\lambda \gt $ 4.4 µm, and (3) change in behaviour at 8.3–8.5 µm, potentially corresponding to silicate absorption. We interpret the light curves observed with both NIRSpec and MIRI as likely stemming from (1) a deep pressure level driving the double-peaked variability seen in WISE 1049B at wavelengths $\lt $2.3 and $\gt $8.5 µm, (2) an intermediate pressure level shaping the light-curve morphology between 2.3 and 4.2 µm, and (3) a higher altitude pressure level producing single-peaked and plateaued light-curve behaviour between 4.2 and 8.5 µm.

Scoping Review of Wounds in Hospitalized Adults with COVID-19 Over the First Three Years of the Pandemic.

To synthesize the literature on skin failure and pressure injuries among hospitalized patients with COVID-19. An electronic literature search using relevant keywords and controlled vocabulary was conducted in March 2023 on MEDLINE/PubMed, Embase, and CINAHL. Manual citation searches of included articles and grey literature, including the Wound, Ostomy, and Continence Nurses Society website were performed. Articles published in English between 2020 and April 2023 were considered. Articles were included if they reported on COVID-19 positive hospitalized adults with wounds that were not present upon admission. A total of 31 articles met these criteria. Covidence was used to extract the data and was reviewed by multiple team members. Of the 31 studies, 27 reported new onset skin lesions during hospitalization. Wounds were classified as pressure injuries, skin failure, livedo racemosea and/or, retiform purpura, and associated with microvascular thrombosisthrombotic vasculopathy. Most pressure injuries were associated with prone position and affected patients often had multiple comorbidities including hypertension, diabetes mellitus, end-stage renal disease, heart disease, and COPD. Four articles highlighted an increased risk of new onset wounds, and three emphasized the importance of distinguishing deep tissue pressure injuries from ischemic-related lesions in patients with COVID-19. The evidence suggests an increased risk of ischemic lesions and pressure injuries (PI) in patients with COVID-19 infection. This phenomenon may have inflated the numbers of PI during the pandemic and adversely affected nursing quality measures in acute care environments.

Sponge-incorporated VS Multilayer Padding Long Leg Cast to Prevent Pediatric Heel Pressure Injury: A Randomized Controlled Trial

Objective: To measure and compare the incidence of cast-related pressure injuries at the heel between sponge-incorporated long leg cast and multilayer padding cast following orthopedic lower extremity surgery. Materials and Methods: Patients aged 1 to 18 years who were scheduled for elective lower extremity soft tissue surgery were recruited. They were equally randomized into two groups: sponge padding cast (Group 1) and multilayer padding cast (Group 2). A multilayer padding cast, consisting of five layers of Webril®, was applied to the heel and bony prominence areas. At the 2nd and 4th weeks postoperatively, cast-related heel pressure injuries were evaluated using the 2016 National Pressure Ulcer Advisory Panel (NPUAP) staging system. Changes in alignment and other complications were also recorded. Results: 100 patients were recruited. At two weeks postoperatively, the incidence of cast-related heel pressure injuries in Group 1 was 4/46 cases (8.7%), with all cases being stage 1. In Group 2, there were 6/54 cases (11.1%), with 3 cases in stage 1 and 3 cases in deep tissue pressure injury (p=0.479). At four weeks postoperatively, Group 1 had 6/46 cases (13%), with 4/46 cases (8.7%) being stage 1 and 2/46 cases (4.3%) being deep tissue pressure injuries. Group 2 had 6/54 cases (11.1%) (p&gt;0.99), with all cases being stage 1. There was no statistical difference in loss of alignment. No serious complications, such as compartment syndrome or neurovascular injury, were found. Conclusion: The incidence of cast-related heel pressure injury was comparable between sponge padding cast and a multilayer cotton padding cast.

Gracilis muscle flap for reconstruction of extensive soft tissue damage to the palm.

The reconstruction of a large palmar soft tissue defect is a challenge to restore both aesthetics and functionality. Reconstruction with fascio-cutaneous and fascial flaps are the most widely used in the literature, few cases are reported using muscular free flap. We report our experience with the use of the free gracilis muscle flap for palmar soft tissue reconstruction in patients with complex hand traumas. We review nine cases of complex soft tissue reconstruction to the palm of the hand using the free gracilis muscle flap performed over a period of 20 years. Eight cases involved acute trauma with damage to underlying structures, necessitating multiple surgical procedures. With an average follow-up of 36 months, the free gracilis muscle flap reconstruction enabled patients to achieve good grip, with skin quality resistant to chronic mechanical stress. All patients recovered a protective sensation to deep pressure. The hand's aesthetic appearance was restored in all cases. Flap harvesting altered neither the function nor silhouette of the donor site. The optimal palmar reconstruction technique depends on patient characteristics, associated trauma, and defect size. In our opinion, the gracilis muscle flap technique is both straightforward and effective in restoring mechanical function of the hand, particularly when a large area of the palm has been impacted.

Managing deepsea oil spills through a systematic modeling approach

Offshore oil exploration and production in deepwater are associated with environmental risks to marine ecosystems. This research introduces DWOSM (Deep Water Oil Spill Model), a three-dimensional Lagrangian model, which is developed to simulate the transport and fate of oil spills resulting from subsea blowouts. DWOSM comprises three interconnected modules: DWOSM-DSD, which predicts the oil droplet size distribution from a blowout release; DWOSM-NearField, simulating plume dynamics and tracking oil droplets within the plume region; and DWOSM-FarField, modeling the evolution of dispersed oil beyond the near-field. Compared to other oil spill models, this integrated approach improves the transition between near and far fields using a near-field particle tracking algorithm. It also employs the thermodynamic models to enable the prediction of oil properties under varying deep water pressure and temperature. To gauge the reliability and efficacy of DWOSM, a hypothetical case situated within a North American context is employed for model testing. The DWOSM and its each module are juxtaposed with other established oil spill models. The outcomes indicate that DWOSM yields comparable results to these models by providing reasonable predictions of a deepwater blowout. The model's verification through case scenario testing and comparison underscores its potential as a decision tool for assessing and managing the potential environmental impacts of offshore petroleum activities.

PERSEPSI TERHADAP TINGKAT KECEMASAN IBU PRIMIGRAVIDA DALAM MENGHADAPI PERSALINAN DI PMB MELIANA

Anxiety is a normal condition that occurs in various circumstances, such as growth, new experiences (Heriani, 2016). Anxiety is a feeling of fear that has no clear cause and is not supported by the existing situation. Anxiety can be felt by everyone if they experience deep pressure and feelings that cause psychiatric problems and can develop over a long period of time. Anxiety disorders are one of the most common psychiatric disorders. According to the National Comority Study report, one in four people meet the diagnostic criteria for at least one anxiety disorder. Anxiety symptoms are different for each individual. Symptoms of anxiety can include restlessness, heart palpitations, tremors, and more. Pregnancy is a source of stress and anxiety, especially for mentally unstable pregnant women. In general, pregnant women experiencing pregnancy for the first time will feel happy and increasingly curious about their changes as well as the development of the fetus. But at the same time, pregnant women also feel worried. This type of research is analytical survey research with a cross-sectional approach where data relating to the independent variable and dependent variable are collected simultaneously or at the same time. This method was used by researchers to determine the perception of the level of anxiety of primigravida mothers in facing the birth process. Based on the results of age research on the perception and anxiety of primigravida pregnant women in the age group &lt;20 years, totaling 13 people, of which 5 people (38.5%) had a good perception of childbirth and 8 people (61.5%) had a bad perception. towards childbirth. Meanwhile, in the 20-35 year age group, there were 20 people, of whom 15 people (75.0%) had a good perception, and 5 people (25.0%) had a bad perception. According to the results of anxiety levels in people under 20 years old, 7 people (53.8%) felt mild anxiety, 2 people (15.4%) felt moderate anxiety, 3 people (23.1%) felt ) severe anxiety and 1 person (7.7%) panicked.

Dendritic epidermal T cell hydrogel induces the polarization of M2 macrophages to promote the healing of deep tissue pressure injury

Dendritic epidermal T cells (DETCs) have been shown to promote wound healing. However, the mechanisms involved need to be better understood. In the present study, we investigated the role and mechanism of DETCs in deep tissue pressure injury (DTPI). We established the DTPI model using C57BL/6 mice. Then, DTPI was evaluated and analyzed by histological staining, immunohistochemistry, real-time PCR, Western blotting, and flow cytometry in different treatment groups (DETCs, DETCs/gel, Matrigel, Saline, and Normal group). The results showed that insulin-like growth factor 1 and vascular endothelial growth factor-A expression increased after local DETCs and DETCs/gel implantation in DTPI on days 3 and 7. M1 (inducible nitric oxide synthas-marked) macrophages were predominant at 3 days after DTPI. At 7 days, M1 macrophages were decreased, and M2 (CD206-marked) macrophages were increased in the DETCs and DETCs/gel groups. In vitro, in the co-culture of DETCs and RAW264.7, CD206 expression was significantly increased in M2 macrophages. In addition, Interleukin-17A initially inhibited wound healing 1 day after injury. However, it promoted wound healing at 7, 14, and 21 days after treatment with DETCs and DETCs/gel, respectively. In conclusion, our data suggest that exogenous DETCs improve DTPI wound healing by regulating M1 to M2 macrophage polarization.

The role of atmospheric aerosols on severe convective precipitation in a Mediterranean coastal region

Liguria, located in the Northwest of Italy, is one of the Italian regions hit in the recent past by some of the most severe precipitation events among the ones observed in Italy. From a synoptic point of view, similar configurations characterize the extreme events that affected Liguria, i.e. the simultaneous presence of a deep pressure minimum west of the region and a strong high pressure over eastern Europe. Such conditions are favorable to the triggering of a quasi-stationary mesoscale V-shaped convective system over the Ligurian Sea. Furthermore, this kind of configuration is favorable to the formation and intrusion of wide plumes of aerosol, mainly mineral dust from the Sahara Desert and sea salt aerosols generated under high wind conditions in the Mediterranean basin. The present study aims at evaluating the impact that these aerosol plumes can have on meteorological fields during the triggering and evolution of the deep convective systems responsible for the Liguria flooding events. This study is carried out through numerical simulations performed with the WRF-Chem model, version 4.0. In particular, our main aim is to investigate the influence that the so-called direct (aerosol-radiation) and indirect (aerosol-cloud) interactions may have on mesoscale V-shape convective systems and on the associated rainfall events. In the simulations in which the direct aerosol effects are switched on, a consistent weakening signal is identified in the wind speed in all simulations; a major role seems to be played by the increase of downward longwave radiation in the presence of aerosol, that, by reducing the land-sea temperature gradient, causes the weakening of surface winds. More complex are the consequences of aerosol on the amount/intensity of the resulting precipitations. Unexpectedly, a reduced convergence is not necessarily associated with a weakening of precipitation and in half of the studied cases the interaction between aerosol, moisture and radiation increases the instability despite the reduced dynamical forcing due to the weakening of the convergence.