The H1 and ZEUS collaborations at the electron-proton collider HERA collected e ± p scattering data corresponding to an integrated luminosity of about 1 fb −1 . The data were taken at proton beam energies of 920, 820, 575 and 460 GeV and an electron beam energy of 27.5 GeV, with different electric charges and longitudinal polarisation of the electron beam. Using these data inclusive neutral and charged current deep inelastic cross sections were measured over six orders of magnitude in negative four-momentum-transfer squared, Q 2 , and Bjorken x . A combination of all inclusive cross sections, published by the H1 and ZEUS collaborations at HERA, was performed. Using these combined HERA data and the individual H1 and ZEUS data taken using the polarised electron beams, the proton structure functions F 2 , F γZ 2 , x F γZ 3 and F L were obtained, and scaling violations, electroweak unification, and polarisation effects in the charged current process were demonstrated. The combined cross sections were used as a sole input to QCD analyses at leading, next-to-leading and next-to-next-to-leading orders, providing a new set of parton distribution functions, denoted as HERAPDF2.0. An extension of the analysis by including HERA data on charm and jet production allowed a simultaneous determination of parton distributions and the strong coupling.