Decrease In Mean Temperature Research Articles

Mortality risk and burden of aortic aneurysm and dissection attributable to low temperatures: A nationwide case-crossover analysis in Brazil, a predominantly tropical country

BackgroundLow temperatures are adverse contributors to cardiovascular diseases, but the associations between short-term exposure to cold and the risk of death from aortic dissection and aneurysm remain unclear, particularly in tropical regions. ObjectiveThis study was conducted based on 123,951 records of deaths caused by aortic dissection and aneurysms extracted from the national Mortality Information System in Brazil between 2000 and 2019. MethodsRelative risks and 95 % confidence intervals (CI) for the aortic-related deaths associated with low ambient temperatures were estimated using the conditional logistic model combined with the distributed lag nonlinear model. Subgroup analyses were performed by age group, sex, race, education level, and residential region. Furthermore, this study calculated the number and fraction of aortic-related deaths attributed to temperatures below the temperature threshold to quantify the cold-related mortality burden of aortic diseases. ResultsDuring the study period, aortic-related deaths and mortality rates in Brazil exhibited a steady increase, rising from 4419 (2.66/100,000) in 2000 to 8152 (3.88/100,000) in 2019. Under the identified temperature threshold (26 °C), per 1 °C decrease in daily mean temperature was associated with a 4.77 % (95 % CI: 4.35, 5.19) increase in mortality risk of aortic-related diseases over lag 0–3 days. Females, individuals aged 50 years or older, Asian and Black race, and northern residents were more susceptible to low temperatures. Low temperatures were responsible for 19.10 % (95 % CI: 17.71, 20.45) of aortic-related deaths in Brazil. ConclusionThis study highlights that low temperatures were associated with an increased risk of aortic-related deaths, with a remarkable burden even in this predominantly tropical country.

Detrimental effects of scene manipulations on temperature-based time since death estimation

In forensic casework, time since death (TSD) estimations may play a crucial role to establish chains of events as well as for alibi assessment in homicide cases. Classical TSD estimation relies on reasonably stable ambient temperatures and a correct documentation of ambient and rectal temperatures. This constancy is in some cases disturbed by post-discovery alterations of the crime scene, e.g. opening a window. In order to develop a better understanding of this alteration-based detrimental impact on TSD estimation as well as to identify feasible recommendations for casework, the present pilot study examined ambient temperature effects of different window opening scenarios regarding various time intervals (5 to 360 min) in a furnished 10 m2 apartment during winter. In this context, in addition to the ambient temperature and thus the cooling rate of the room, re-approximation to initial room temperature, potential influences on a nomogram-based time since death estimation using a fictitious case, and the impact of the measurement height above the ground were investigated. Our data indicate a significant reduction of the mean temperature decrease rate after 15 min regardless of the remaining opening time and a correlation with the size of the respective opening surfaces. Re-approximation to initial room temperatures was observed with up to three times longer than the initial opening time. There was no evidence of a substantial advantage of temperature measurements above the level of the corpse (> 0.1 m). The limitations of the study and its applicability for forensic casework are critically reviewed.

Precipitation seasonality determines the potential distribution of Hyaena hyaena in Saudi Arabia: Towards conservation planning

Hyaena hyaena is a carnivorous mammal that inhabits a broad variety of habitat types and ecological niches, H. hyaena spread in the Arabian Peninsula excluding Rub Al Khali and the desert of Nafud. In Saudi Arabia, it can be found commonly in the western mountains and the open land near agricultural areas such as valleys and lava fields (Harat). However, the H. hyaena is considered to be globally “Near Threatened” (NC) according to (IUCN) Red List as a consequence of a drop in carrion as a result of a reduction in the population of big predators and their prey, eradication practices, and fragmentation and loss of their habitat. The current study seeks to evaluate the distribution of H. hyaena in Saudi Arabia in relation to a number of environmental parameters, as well as assess the possible appropriateness of different habitats for it under climate change scenarios, and provide significant insights for future conservation strategies. The species distribution models (SDMs) tools were employed to map and monitor the distribution of H. hyaena, and then provide a prediction of species distribution patterns. Multicollinearity analysis of the total 19 bioclimatic variables and topographic roughness index resulted in seven uncorrelated variables with VIF < 5, which had been used in the ensemble modeling. The result of our study showed that the decrease in seasonal precipitation will lead to a decrease in the probability of the presence of H. hyaena in Saudi Arabia and The probability of finding H. hyaena in Saudi Arabia decreases as the driest quarter and wettest quarter mean temperature decreases.

The Role of Southeast Asian Island Topography on Indo‐Pacific Climate and Silicate Weathering

AbstractThe geography of the Southeast Asian Islands (SEAI) has changed over the last 15 million years, as a result of tectonic processes contributing to both increased land area and high topography. The presence of the additional land area has been postulated to enhance convective rainfall, facilitating both increased silicate weathering and the development of the modern‐day Walker circulation. Using an Earth System Model in conjunction with a climate‐silicate weathering model, we argue instead for a significant role of SEAI topography for both effects. SEAI topography increases orographic rainfall over land, through intercepting moist Asian‐Australian monsoon winds and enhancing land‐sea breezes. Large‐scale atmospheric uplift over the SEAI region increases by ∼14% as a consequence of increased rainfall over the SEAI and enhancement through dynamical ocean‐atmosphere feedback. The atmospheric zonal overturning circulation over the Indo‐Pacific increases modestly arising from dynamical ocean‐atmosphere feedback, more strongly over the tropical Indian Ocean. On the other hand, the effect of the SEAI topography on global silicate weathering is substantial, resulting in a ∼109 ppm reduction in equilibrium pCO2 and decrease in global mean temperature by ∼1.7ºC. The chemical weathering increase comes from both enhanced physical erosion rates and increased rainfall due to the presence of SEAI topography. The lowering of pCO2 by SEAI topography also enhances the Indo‐Pacific atmospheric zonal overturning circulation. Our results support a significant role for the progressive emergence of SEAI topography in global cooling over the last several million years.

Evaluating thermal response when elderly people using local cooling devices: Correlation among overall and local thermal sensation with skin temperature

The thermal comfort of elderly people in warm indoor environments is important because of their higher risk of heat stress. The use of local cooling devices may help alleviate heat stress. In this study, 26 elderly participants were recruited for climate chamber experiments in neutral (26 °C, 40 % relative humidity (RH)), slightly warm (29 °C, 40 % RH; 28 °C, 60 % RH), and warm (33 °C, 40 % RH; 32 °C, 50 % RH) environments. Three local cooling devices were tested: a table fan, evaporative cooling device, and air-cooled jacket. This study found, in different warm environments, the use of local cooling devices by the elderly results in an mean skin temperature decrease of no more than 0.5 °C. The thermal sensation in the head and torso has the most significant impact on overall thermal sensation. The mean skin temperature (MST) remains an effective physiological indicator for estimating overall thermal sensation after using local cooling devices. The skin temperature in the head, limbs, and extremities plays a substantial role in predicting overall thermal sensation. The thermosensory mean skin temperature (TMST) proposed based on the skin temperature of these parts can more accurately predict overall thermal sensation than MST. This study provides a reference for the development of future local cooling devices. This study has implications for guiding the selection of devices for nursing homes or residential environments for the elderly, and it can be utilized to formulate recommendations for improving device design.

Low ambient temperature exposure increases the risk of ischemic stroke by promoting platelet activation

BackgroundAccumulating epidemiological evidence suggests the association between low ambient temperature exposure and the risk of ischemic stroke, but the underlying mechanisms remain unclear. ObjectiveGiven the crucial role of platelet activation and thrombosis in ischemic stroke, this study aims to investigate the effect of ambient temperature on platelet activation through multi-center clinical data in Tianjin as well as animal experiments. MethodsFrom 2018 to 2020, nearly 3000 ischemic stroke patients from three stroke centers in Tianjin were included in the analysis, among them the ADP induced platelet aggregation rate was available. Meteorological data from the same period had also been collected. After controlling for confounding factors, the generalized additive mixed model (GAMM) was used to evaluate the correlation between environmental temperature and platelet aggregation rate. In further animal experiments, platelet function assessments were conducted on mice from the cold exposure group and the normal temperature group, including platelet aggregation, spreading, and clot retraction. Additionally, tail bleeding and mesentery thrombosis were also tested to monitor hemostasis and thrombosis in vivo. ResultA nonlinear “S” shaped relationship between outdoor temperature and platelet aggregation was found. Each 1 °C decrease of mean temperature was associated with an increase of 7.77 % (95 % CI: 2.06 % - 13.48 %) in platelet aggregation. The ambient temperature is not related to other platelet parameters. Subgroup analysis found that males, people aged ≥65 years, and hypertensive individuals are more susceptible to temperature changes. Furthermore, animal experiments demonstrated that the increased CIRBP levels and subsequent activation of p-AKT/p-ERK may be one of the reasons for cold exposure induced platelets activation. ConclusionBoth clinical data and basic research support that low ambient temperature exposure has the potential to increase platelet activation. These results provide a basis for understanding the potential mechanism of temperature variations on the pathogenesis of cerebrovascular diseases.

Effects of masks on physiological and thermal responses of college students during outdoor activities

In the post COVID-19 era, people have adjusted to coexistence with viruses and air pollution, and masks have become basic personal protective equipment. However, we know little about the physiological and thermal feedback when wearing masks and performing outdoor activities varying in intensity. We combined mask types (no mask, surgical, N95, and cloth) and activity intensities (light, moderate, and vigorous) to investigate personal physiological and thermal responses in outdoor environments. We had four principal findings: 1) perioral temperature (Talocal) was the highest under cloth masks and perioral relative humidity (RHlocal) was the highest under cloth or N95 masks during moderate and vigorous intensity activities; 2) “breathing resistance” scores were the highest at all stages when wearing masks; 3) wearing masks had a positive effect on the decrease of mean skin temperature (MST), and this effect was the greatest for surgical masks; and 4) during exercise, thermal sensation vote (TSV) was mainly influenced by Talocal and RHlocal in the dead space under masks. TSV was primarily affected by RHlocal and ΔAH under surgical and cloth masks, while TSV was primarily influenced by Tg under N95 masks. Our findings provide basic information supporting mask selections linked to activity intensity in outdoor settings.

Recovery with a fan-cooling jacket after exposure to high solar radiation during exercise in hot outdoor environments.

The study aimed to investigate the effect of body cooling with a fan-cooling jacket on body temperature responses during recovery after exercise when exposed to high solar radiation in a hot outdoor environment. Nine males cycled using ergometer until their rectal temperature increased to 38.50 °C in hot outdoor environments, followed by body cooling recovery in warm indoor environments. Subjects repeatedly performed the cycling exercise protocol, which consisted of one set of 5 min at a load of 1.5 watt/kg body weight and 15 min at a load of 2.0 watt/kg body weight at 60 rpm. Body cooling recovery consisted of cold water ingestion (10°C: CON) or cold water ingestion + wearing a fan-cooling jacket (FAN) until the rectal temperature decreased to 37.75°C. The time for the rectal temperature to reach 38.5°C did not differ between the two trials. The rate of decrease in rectal temperature at recovery tended to be higher in FAN trial than in CON trial (P = 0.082). The rate of decrease in tympanic temperature was higher in FAN trials than in CON trials (P = 0.002). The rate of decrease in mean skin temperature at the first 20 min of recovery was higher in FAN than in CON trial (P = 0.013). Body cooling recovery with a fan-cooling jacket in addition to cold water ingestion may be effective in reducing elevated tympanic and skin temperatures after exercise in the heat under a clear sky, but may be difficult to decrease rectal temperature.

Experimental study on improvement effect of a cooling vest on thermal comfort of manufactory workers

This study aimed to examine the effect of a personal cooling vest on improving the thermal comfort of workers in a warm and hot indoor environment. The experiments were conducted under three temperatures: 27 °C, 29 °C, and 31 °C. Twenty subjects (10 males and 10 females) were recruited. They were required to perform three activities (i.e., sitting, light packing and heavy packing activity). Subjects experienced two scenarios: the one wearing the cooling vest (CV), and the other without the cooling vest (NCV). The skin temperature and peripheral oxygen saturation (SpO2) were measured. Subjects' thermal comfort and sensation votes were collected, and their responses to two cognitive tasks and working efficiency were also recorded. The use of CV reduced subjects' local and mean skin temperature effectively. Compared with the light packing activity, the decrease of local and mean skin temperature was smaller during heavy packing. With the use of CV, the SpO2 in the three activities and work efficiency in the two packing activities tended to increase. The result of subjective responses showed that their thermal sensation and comfort votes were also significantly improved by the use of CV. With the increase of activity level, the improving effect tended to decline, in which the decrement of thermal sensation vote became smaller in the heavy packing activity. The results of cognitive ability tests showed that the tasks’ completion time was not affected by the use of CV, while the error rate of the Stroop test decreased.

Assessing the sustainability of yellow anaconda (Eunectes notaeus) harvest.

Sustainable wildlife management is necessary to guarantee the viability of source populations; but it is rarely practiced in the tropics. The yellow anaconda (Eunectes notaeus) has long been harvested for its leather. Since 2002 its harvest has operated under a management program in northeastern Argentina, which relies on adaptive management practices, that limit the minimum body length permitted for harvesting, the number of active hunters and the length of hunting seasons. Here we investigated the effects of yellow anaconda harvest on its demography based on 2002-2019 data and show that exploitation levels are sustainable. The gradual reduction in annual hunting effort, due to a decrease in the number of hunters and hunting season duration, reduced the total number of anacondas harvested. Conversely, captures per unit effort increased across the study period. The body size of anacondas was not influenced by the harvesting, and more females than males were caught. We also found that a decrease in mean temperature positively influenced anaconda harvest and the capture of giant individuals. Because sustainable use is a powerful tool for conservation, and anacondas are widespread in South America, these discoveries are highly applicable to other species and regions.

Use of Landsat 8 and UAV Images to Assess Changes in Temperature and Evapotranspiration by Economic Trees following Foliar Spraying with Light-Reflecting Compounds

Pistachio is an important economic crop in arid and semi-arid regions of Iran. A major problem leading to a reduction in crop quality and reduced marketability is extreme air temperature in summer, which causes sunburn of pistachio leaves and fruit. A solution proposed to deal with the negative effects of high temperatures and increase water consumption efficiency in pistachio orchards is use of light-reflecting compounds. This study investigated the effect of foliar application of gypsum, sulfur, and NAX-95 (calcium-based suspension coating) to trees in a pistachio orchard (150 ha) in central Iran. The effect of these foliar products is assessed at plot scale, using control plots sprayed with calcium sulfate, based on temperature and evapotranspiration changes analyzed through remote sensing. Landsat 8 sensor images and RGB images collected by UAVs (spatial resolution of 30 m and 20 cm, respectively), on the same dates, before and after foliar spray application, were merged using the PCA method and bilinear interpolation re-sampling. Land surface temperature (LST) was then estimated using the split-window algorithm, and daily evapotranspiration using the surface energy balance algorithm for land (SEBAL) algorithm. A land use map was prepared and used to isolate pistachio trees in the field and assess weed cover, whose effect was not accounted. The results showed that temperature remained constant in the control plot between the spraying dates, indicating no environmental changes. In the main plots, gypsum had the greatest effect in reducing the temperature of pistachio trees. The plots with foliar spraying with gypsum displayed a mean tree temperature (47–48 °C) decrease of 3.3 °C in comparison with the control plots (&gt;49 °C), leading to an average decline in evapotranspiration of 0.18 mm/day. NAX-95 and sulfur reduced tree temperature by on average 1.3 °C and 0.6 °C, respectively. Thus, gypsum is the most suitable foliar-spraying compound to lower the temperature of pistachio trees, reduce the water requirement, and increase crop productivity.

Aboveground biomass of marshes in Northeast China: Spatial pattern and annual changes responding to climate change

Examining vegetation aboveground biomass (AGB) changes is important to understanding wetland carbon sequestration. Here, we combined the field-measured AGB data (458 samples) from 2009 to 2021, moderate resolution imaging spectroradiometer reflectance products, and climatic data to reveal the AGB variations of marshes in Northeast China by comparing various models driven by different indicators. The results indicated that random forest model driven by six vegetation indices, land surface temperature, and land surface water index achieved accurate marsh AGB estimation with R2 being 0.78 and relative error being 16.71%. The mean marsh AGB in Northeast China from 2000 to 2021 was 682.89 ± 31.69 g·m−2, which generally increased from north to south in space. Temporally, annual marsh AGB declined slowly at a rate of 3.45 g·m−2·year−1 during the past 21 years driven mainly by the decrease in summer mean temperature that was characterized by a significantly positive correlation between them. Nevertheless, we highlighted that the temporal changes of marsh AGB spatially varied in response to inconsistent climate change, thus place-based measures are required for sustainable management of marshes.

Temperature determines the shift of thermal neutral zone and influences thermogenic capacity in striped hamsters.

The thermoneutral zone (TNZ) reflects the adaptation of mammals to their natural habitat. However, it remains unclear how TNZ shifts in response to variations in ambient temperature. To test the hypothesis that ambient temperature plays a key role in determining TNZ variations between seasons, we measured metabolic rate, body temperature, and cytochrome c oxidase (COX) activity of several visceral organs in striped hamsters (Cricetulus barabensis) either acclimated to semi-natural conditions over a year, or subjected to a gradual decrease in mean temperature from 30 ± 1°C to -15 ± 1°C. The TNZ range in striped hamsters differed seasonally, with a wider TNZ and a lower lower-critical temperature in winter compared to summer. The hamsters showed a considerable leftward shift of lower-critical temperature from 30°C to 20°C after the ambient temperature of acclimation from 30°C down to -15°C, whereas the upper-critical temperature of TNZ remained fixed at 32.5°C. The resting metabolic rate in thermoneutral zone (RMRt), nonshivering thermogenesis (NST), and COX activity of brown adipose tissue, liver, skeletal muscle, brain, and kidneys, increased significantly in hamsters acclimated at lower ambient temperatures. Following acute exposure to 5°C and -15°C, hamsters acclimated to 32.5°C had significantly lower maximal NST and lower serum thyroid tri-iodothyronine (T3 ) levels compared to those kept at 23°C. These findings suggest that acclimation to the upper-critical temperature of TNZ impairs the hamsters' thermogenic capacity to cope with extreme cold temperature. Reduced ambient temperature was mainly responsible for the leftward shift of TNZ in striped hamsters, which reflects the adaptation to cold environments.

Effect of oxidizer dilution on thermophotovoltaic performance of premixed ammonia/hydrogen/air combustion in radial micro-combustor

Present research deals with the combustion characteristics, thermal performance, and emissions analyses of a radial micro-combustor for thermo-photovoltaic application. Simulations are carried out for premixed ammonia/hydrogen/air combustion with different inlet velocities and air dilution levels with N2. Influences of input parameters on the thermal performance of micro-combustor, the total energy conversion efficiency of the micro thermo-photovoltaic system, OH distribution, recirculation zone characteristics, flame blowout limits and NOx-N2O emissions are examined. The results imply that elevating inlet velocity in the studied range enhances the uniformity factor of temperature distribution in the fluid and solid domains. The maximum value of the total energy conversion efficiency was obtained to be 8.2 % corresponding to the 6.6 W of output electric power. On the other hand, the present results showed that a higher dilution level of air (up to 84 % N2 on volume basis) results in a significant increase in temperature distribution uniformity and consequently a decrease in mean temperature and total thermo-photovoltaic efficiency. Moreover, such increment in dilution level results in higher N2O emission at lower velocities and consequently a significant decrease in NOx emission level up to 58 %. Finally, reaction pathway analysis showed that the main NO production pathway remains unchanged in NH3 → NH2 → HNO → NO route with increasing inlet velocity and dilution level.

Modeling the climate sensitivity of Patagonian glaciers and their responses to climatic change during the global last glacial maximum

Investigation of the behavior of the former ice sheet over Patagonia aids better understanding of ice-climate interactions and has important implications for deciphering how modern glaciers will respond to rapid increase in global temperature. Here, we use a 1-km resolution ice sheet model to identify the climate sensitivity of Patagonian glaciers and examine their responses to climatic change during the global Last Glacial Maximum (gLGM). Our results demonstrate that the total glacier area increases by ∼78 × 103 km2 and the equilibrium-line altitude (ELA) lowers by ∼163 m for every 1 °C of cooling under modern precipitation regime. Keeping temperature unchanged, there is an increase of total glacier area by ∼21 × 103 km2 and a ΔELA by ∼64 m for every doubling in precipitation. According to the multimodel ensemble mean of 21 PMIP models, an overall colder and drier climate prevails over Patagonia during the gLGM, with a decrease of annual mean temperature and precipitation by ∼4.7 °C and 12%, respectively. Under the modeled gLGM climate, there is an extensive ice sheet (∼387 × 103 km2) almost completely covering the Patagonian Andes, which results largely from the cooling with positive contribution from sea-level fall. The Patagonian ice sheet is drained by ice streams at the western margins and fast-flowing outlet glaciers to the east, with a north-to-south ice divide mainly extending the southern Patagonian Andes. Additionally, the erosion potential induced by the ice sheet exhibits a very strong localization over the fjords and valleys, resembling the pattern of ice velocity. The modeled ice sheet extent and ice flow pattern during the gLGM match well with the latest empirical reconstructions (though with spatial discrepancies), whereas the total ice volume is underestimated. However, the modeled Patagonian ice sheet exhibits high sensitivity to climatic forcing and the values of ice sheet model parameters used.

Acute effects of ambient temperature on lung function of a panel of school children living in Dhaka, Bangladesh

IntroductionShort-term exposure to ambient temperature plays a significant role in human health. However, studies examining ambient temperature and lung function are scarce in locations with a tropical environment. To address this research gap, the current study investigated the effects of short-term ambient temperature on lung function in children and seasonal variation in this association in Dhaka, Bangladesh. MethodsThe study was conducted in three schools located in three cities inside and around Dhaka. Repeated lung function measurements were obtained from a panel of 315 school children (including 86 asthmatic children) aged 9–16 years in 2013. Linear mixed-effects models adjusted for potential confounders were used to examine the effect of ambient temperature on lung function. ResultsShort-term exposure to low ambient temperature was associated with a significant decrement in children's lung function. For each 1 °C decrease in daily mean temperature at cumulative lag of the current and previous day, lung function parameter values were −3.02% (95% CI, −1.69 to −4.35) for peak expiratory flow (PEF), and −1.48% (95% CI, −0.75 to −2.22) for forced expiratory volume within 1 s (FEV1). A significant seasonal variation was also observed in these associations, as the estimated adverse effects of decrease in daily mean temperature on lung function measures were primarily evident in winter. DiscussionThis study suggests that short-term ambient exposure to decrease in temperature adversely affect lung function. A significant seasonal modification in the association between temperature and lung function was also observed for these children living in an environment with a tropical climatic condition as the adverse effect of decrease in ambient temperature was primarily observed in winter than in summer.

Evaluation of efficacy and safety of subcutaneous acetaminophen in geriatrics and palliative care (APAPSUBQ)

IntroductionSubcutaneous infusion (SC) or hypodermoclysis is an old perfusion technique that is often used off-label although it has been shown to be effective. Acetaminophen (paracetamol) subcutaneous injection is performed in some centers despite the lack of conclusive evidence on its effectiveness. This study aims to evaluate the efficacy of subcutaneous infusion of Acetaminophen in the treatment of pain and fever in geriatrics and in palliative care and to determine its safety profile and possible side effects.Material and methodsThis experimental study was conducted between 2018 and 2019 on adult patients in palliative care or in geriatrics in several hospitals and nursing homes in Lebanon. Primary outcomes were change in temperature; change in pain score on the numerical rating scale (NS) or on the Algoplus scale after 60 min from the start of the infusion; and the appearance of local side effects at the infusion site. Changes in the various parameters at 30 min and 180 min were also evaluated as secondary outcomes.ResultsThirty-one patients were included in the study, with a total of 120 doses of acetaminophen. At 60 min, the mean decrease in pain on the NS was 5.35 points, while the mean decrease in temperature was 0.79 degrees Celsius. At 60 min, 75%, CI = [47.62-92.73] of the patients who received acetaminophen for pain and 66.67%, CI = [38.38-88.17] of those who received it for fever had clinically significant improvement. The overall effect of subcutaneous acetaminophen, defined as any clinically significant effect on pain or fever, was 70.97%, CI = [51.96-85.78]. The overall effect at 30 min and at 180 min was 23.33%, CI = [9.93-42.28] and 87.10%, CI = [70.17-96.37], respectively. The side effects reported 30 min after the injection and observed after at least one of the doses were: local edema in 16 patients (51.61%), induration in one patient (3.23%), local pain in one patient (3.23%) and local heat in one patient (3.23%). At 180 min, only 2 patients (6.45%) still had edema at the infusion site.ConclusionSubcutaneous administration of acetaminophen is effective and well tolerated in geriatric and palliative care patients. It is appropriate when no other route is available, especially for home-based care. Comparative studies are needed to allow the expansion of this practice.

Evolution of weather parameters and trend analysis over Junagadh, Gujarat

Climate change is one of the most important worldwide issues talked among the scientists and researchers. The temperature and rainfall trends are analyzed for meteorological data of Junagadh station in Gujarat. India over approximately last three decades stretching between years 1971 to 2013. The long–term change in temperature and rainfall has been assessed by linear trend analysis. The increasing trend in mean monthly maximum temperature (MMAX) and total mean rainfall (TMRF) is confirmed by Mann-Kendall trend test. It is evident from that monthly mean temperature have increased significantly for all the months except the months of April and October for which a very weak decrease in mean maximum temperature is observed. This implies that at Junagadh, the highest increase in temperature occurred in November (0.0210C) during 1980-2011 period. The annual mean of monthly maximum temperatures (MMAX) observed an increasing trend having an annual decreasing of 0.0040C year during 1980-2011. It is evident TMRF have increased for the months April, May August and September whereas it shows decreasing trend in January, Feb, March, June, July, October, November and December. This implies that at Junagadh, the highest increase in TMRF occurs in August and increased by (0.029 mm) during the last 1980-2011. The highest decrease in TMRF occurs in June and decreased by (2.153mm) during the same period. The annual mean of total monthly rainfall observed a decreasing trend having an decrease of 0.249 mm/year during the last 31 years.

Long-Term Impact of Continental and Maritime Airflow on Aerosol Environment and Rain Microstructure Near Land–Sea Boundary

The present study deals with the interplay of multiple atmospheric processes in changing the microphysical properties of precipitation during the pre-monsoon season (March–May) using the long-term experimental data of raindrop size distributions (DSDs) spanning over 15 years (2005–2019) obtained at an urban tropical location, Kolkata (22.57°N, 88.37°E), near the land–sea boundary. The changing pattern of air mass flows from the maritime and continental region, which contribute to the formation of precipitation processes, has been responsible for the varying characteristics of rain. Changes in raindrop sizes are related to aerosol properties, cloud features, temperature, and relative humidity that change mass-weighted mean drop diameter ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$D_{m}$ </tex-math></inline-formula> ) differently in low and high rain rate regimes. <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$D_{m}$ </tex-math></inline-formula> has shown an increasing trend over time for low rain rates (< 15 mm/h), but a decreasing trend for high rain rate regimes (≥15 mm/h). An increase (decrease) in mean temperature (relative humidity) below the atmospheric boundary layer (< 1.6 km) has enhanced the evaporation of small raindrops and altered rain microphysical features. Based on satellite observations, it has been found that the increasing aerosol optical depth (AOD) has been accompanied by an increase in cloud effective radius (CER), resulting in the anti-Twomey effect, which is due to the dominance of maritime influence over continental activities. Because of the predominant maritime activities, sea salt aerosols have a greater presence, causing an increase in CER, which consequently prevents raindrops from becoming large enough before they fall, thereby reducing <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$D_{m}$ </tex-math></inline-formula> at high rainfall rates.

Passive antipyretic therapy is not as effective as invasive hypothermia for maintaining normothermia after cardiac arrest.

Targeted temperature management is a class I indication in comatose patients after a cardiac arrest. While the literature has primarily focused on innovative methods to achieve target temperatures, pharmacologic therapy has received little attention. We sought to examine whether pharmacologic therapy using antipyretics is effective in maintaining normothermia in post cardiac arrest patients. Patients ≥18 years who were resuscitated after an in-hospital or out-of-hospital cardiac arrest and admitted at our institution from January 2012 to September 2015 were retrospectively included. Patients were divided into groups based on the method of temperature control that was utilized. The primary outcome was temperature control <38 °C during the first 48 h after the cardiac arrest. 671 patients were identified in Group 1 (no hypothermia), 647 in Group 2 (antipyretics), 44 in Group 3 (invasive hypothermia), and 51 in Group 4 (invasive hypothermia and antipyretics). Mean patient age was 59 (SD ±15.7) years with 40.6% being female. Using Group 1 as the control arm, 57.7% of patients maintained target temperature with antipyretics alone (p < 0.001), compared to 69.3% in the control group and 82.1% in the combined hypothermia groups 3&4 (p = 0.01). Patients receiving both invasive hypothermia and antipyretics (Group 4), had the greatest mean temperature decrease of 5.2 °C. Among patients undergoing targeted temperature management, relying solely on as needed use of antipyretics is not sufficient to maintain temperatures <38 °C. However, antipyretics could be used as an initial strategy if given regularly and/or in conjunction with more aggressive cooling techniques.