Plasmoid instability usually accounts for the onset of fast reconnection events observed in astrophysical plasmas. However, the measured reconnection rate from observations can be one order of magnitude higher than that derived from magnetohydrodynamic (MHD) simulations. In this study, we present the results of magnetic reconnection in the partially ionized low solar atmosphere based on 2.5D MHD simulations. The whole reconnection process covers two different fast reconnection phases. In the first phase, the slow Sweet–Parker reconnection transits to the plasmoid-mediated reconnection, and the reconnection rate reaches about 0.02. In the second phase, a faster explosive reconnection appears, with the reconnection rate reaching above 0.06. At the same time, a sharp decrease in plasma temperature and density at the principle X-point is observed, which is associated with the strong radiative cooling, the ejection of hot plasma from the local reconnection region, or the motion of the principle X-point from a hot and dense region to a cool and less dense region along the narrow current sheet. This causes gas pressure depletion and increases magnetic diffusion at the main X-point, resulting in the local Petschek-like reconnection and a violent and rapid increase in the reconnection rate. This study for the first time reveals a common phenomenon where the plasmoid-dominated reconnection transits to an explosive faster reconnection with a rate approaching the order of 0.1 in partially ionized plasma in the MHD scale.