Sebacate Research Articles

Sustainable bio-based pressure sensitive adhesives from epoxidized soybean oil along with a novel long-chain dibasic acid obtained from sebacic acid and a cardanol-based epoxy resin

Bio-based and sustainable pressure sensitive adhesives (PSAs) were produced from epoxidized soybean oil (ESO) and a novel long-chain dibasic acid (PD) with a number average molecular weight (Mn) > 3.000 Da. PDs were obtained by reacting sebacic acid (SA) with a cardanol-based epoxy resin using unbalanced equivalent acid/epoxy ratios (R) of 1.23, 1.5 and 1.76 and through environmentally sound procedures without the use of catalysts or volatile solvents. Additionally, control PSAs were developed using ESO and SA. All PSAs exhibited glass transition temperature (Tg) values lower than −20 °C, suitable for room temperature applications, and met the Dahlquist criterion. Among the obtained PSAs, the formulation with the PD synthesized with R = 1.5 presented superior pressure-sensitive properties (tack forces of 2.4 N/cm2, shear strength of 430 min, and 180° peel strength of 4 N/cm) compared to those of measured commercial PSAs, under similar conditions. This study introduced an innovative approach to producing bio-based and environmentally friendly PSAs with high performance.

Tomato Root Exudates Infected by Meloidogyne incognita Impact the Colonization of Nematicidal Proteus vulgaris.

Root exudates play a pivotal role in shaping the microbial community in the rhizosphere and can impact the efficacy of bacteria in controlling nematode populations. This study identified Proteus vulgaris BX-1 as significantly effective in controlling Meloidogyne incognita. The infection of tomato plants with this nematode induced noticeable alterations in the composition of tomato root exudates and led to an increased colonization rate of strain BX-1. Further investigation into how strain BX-1 responded to changes in tomato root exudates revealed that specific metabolites, such as caffeic acid, coumarin, salicylic acid, sebacic acid, and butyric acid, strongly attracted strain BX-1. This attraction potentially contributed to its enhanced colonization and improved efficiency in controlling nematodes. Understanding the correlation between specific metabolites in root exudates and the response of antagonistic bacteria provides valuable insights for enhancing their effectiveness as biological control agents against plant-parasitic nematodes.

Synthesis and Characterization of Poly (Erythritol Sebacate)

AbstractErythritol is a sweetener polyol widely distributed in nature. Its industrial production is based on biotechnological fermentative processes using yeasts. It is used essentially in nutrition and pharmaceutical fields. However, due to its still high price, the use of erythritol is not widespread and is lower than that of other polyols. The use of erythritol for polymer synthesis remains largely unexplored by the scientific community. This work describes the synthesis and characterization of polyester, poly (erythritol sebacate) (PES), obtained by thermal polycondensation of erythritol and sebacic acid in a two steps approach. A prepolymerization step was realized at different temperatures (150 °C, 160 °C and 170 °C, respectively) followed by a cure step at 150 °C. It was found that using a higher temperature allows the same degree of polymerization (50%) to be achieved in a shorter period, but this leads to prepolymers with a more heterogeneous oligomeric composition. This is reflected in the final properties of the polymers after curing. Synthesis at 150 °C produced a polymer with superior mechanical performance (ultimate tensile strength: 0.5 MPa; Young’s modulus: 0.44 MPa: elongation at break: 123%) and higher chemical resistance to solvents than polymers synthesized at 160 °C and 170 °C. The glass transition temperature (Tg) is between − 20 and 0 °C for all polymers and density is 1.08 g/cm3. Based on these results, we believe that PES is a good elastomer with tunable properties and potential for selective absorption of molecules, such as ethanol, that could be useful for beverage industry and biotechnological applications. Graphical Abstract

Polyglycerol Sebacate/polycaprolactone/reduced graphene oxide composite scaffold for myocardial tissue engineering

The aim of this research was to fabricate and evaluate polyglycerol sebacate/polycaprolactone/reduced graphene oxide (PGS-PCL-RGO) composite scaffolds for myocardial tissue engineering. Polyglycerol sebacate polymer was synthesized using glycerol and sebacic acid prepolymers, confirmed by Fourier-transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). Six PGS-PCL-RGO composite scaffolds (S1-S6) with various weight ratios were prepared in chloroform (CF) and acetone (Ace) solvents at 8 CF:2Ace and 9 CF:1Ace volume ratios, using the electrospinning method at a rate of 1 ml/h and a voltage of 18 kV. The scaffolds' chemical composition and microstructure were characterized by FTIR, XRD, and scanning electron microscopy (SEM). Further investigations included tensile testing, contact angle testing, four-point probe testing for electrical conductivity, degradation testing, and cytotoxicity testing (MTT). The results showed that adding 2%wt RGO to the composite scaffold decreased fiber diameter and degradation rate, while increasing electrical conductivity and ductility. The 33%PGS-65%PCL-2%RGO (S3) composite scaffold exhibited the lowest degradation rate (23.87 % over 60 days) and the highest electrical conductivity (51E-3 S/m). Mechanical evaluations revealed an elastic modulus of 2.46 MPa and elongation of 62.43 %, aligning closely with the heart muscle's elastomeric properties. The contact angle test indicated that the scaffold was hydrophilic, with a water contact angle of 61 ± 2°. Additionally, the cell toxicity test confirmed that scaffolds containing RGO were non-toxic and supported good cell viability. In conclusion, the 33%PGS-65%PCL-2%RGO composite scaffold exhibits mechanical and structural properties similar to heart tissue, making it an ideal candidate for myocardial tissue engineering.

Kinetic Evaluation and Catalytic Efficiency of Sebacic Acid as a Novel Catalyst in Hydrogen Generation via NaBH4 Alcoholysis Reactions

Kinetic Evaluation and Catalytic Efficiency of Sebacic Acid as a Novel Catalyst in Hydrogen Generation via NaBH4 Alcoholysis Reactions

Synthesis and characterization of high thermal resistance acetal-containing heterocyclic polyamides

This study synthesized a heterocyclic acetal-containing monomer, 7a,14c-dihydronaphtho[2,1-b] naphtho [1′,2′:4,5] furo[3,2-d] furan (DHNF) with a melting point of 230 °C, through the acidic reaction of 2-naphthol and glyoxal. Two types of heterocyclic polyamides were produced via condensation polymerization of DHNF Diamine with terephthalic acid (aromatic diacid) and sebacic acid (aliphatic diacid), achieving melting points exceeding 400 °C. Spectroscopic methods, including Fourier-transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance spectroscopy (1HNMR), were used to identify the synthesized compounds. Thermal analysis, including Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC), demonstrated the thermal stability of the polyamides with acetal functional groups, showing a 10 % weight loss at 193.6 ℃ for PA-1 and 420 ℃ for PA-2, with crystallization temperatures of 155 °C and 180 °C for Types 1 and 2, respectively. The results indicate that the acetal functional group enhances polyamide solubility and processability. Viscometry revealed higher inherent viscosity for PA-2, attributed to its higher molecular weight.

Tribological performance of di-n-octyl sebacate synthesized with carboxylated nano-MoS2/sericite as catalyst

PurposeThis study aims to explore the synthesis and tribological performances of di-n-octyl sebacate (DOS) synthesized with spherical nano-MoS2/sericite (SMS) and carboxylated SMS (CSMS) as catalysts.Design/methodology/approachSMS and CSMS were used as esterification catalysts to synthesize DOS from sebacic acid and n-octanol. The two catalysts were in situ dispersed in the synthesized DOS after the reaction to form suspensions. The tribological performances of the two suspensions after 20 days of storage were studied.FindingsCSMS was more stably dispersed in DOS than SMS, and they reduced friction by 55.6% and 22.2% and wear by 51.3% and 56.5%, respectively. Such results were mainly caused by the COOH on CSMS, which was more conducive to improving the dispersion and friction reduction of CSMS than wear resistance. Another possible reason was the difference between the dispersion amounts of CSMS and SMS in DOS. The sericite of SMS was converted into SiO2 to enhance wear resistance, while that of CSMS only partially generated SiO2, and the rest still remained on the surface to reduce friction.Originality/valueThis work provides a more effective SMS catalytical way for DOS synthesis than the traditional inorganic acid catalytical method. SMS does not need to be separated after reaction and can be dispersed directly in DOS as a lubricant additive. Replacing SMS with CSMS can produce a more stable suspension and reduce friction significantly. This work combined the advantages of surface carboxylation modification and in situ catalytic dispersion and provided alternatives for the synthesis of DOS and the dispersion of MoS2-based lubricant additives.

Bio-based polyurethane triboelectric nanogenerator with superior low-temperature self-healing performance for unmanned surveillance

Damaged flexible triboelectric nanogenerators face difficulties in autonomous healing at low temperatures, limiting their application range. Impeded dynamic network reconstruction presents a challenge in developing materials for autonomous low-temperature healing. This study constructed a multi-dynamic network utilizing both strong and weak hydrogen and disulfide bonds to develop a biobased polyurethane elastomer (PBES-U, prepared from biobased monomers such as itaconic acid, sebacic acid, etc.), featuring a cross-linked network capable of cryogenic self-healing, superior toughness, and reprocessability. This elastomer extends to 1100 % of its original length, achieving 90 % self-healing efficiency at temperatures down to −10 °C due to the low glass transition temperature (Tg, −30 ℃) achieved by modulating the flexibility of chain segments. Consequently, a bio-based TENG (LS-TENG) was produced using this elastomer as a positive friction layer through a dynamic interfacial interlocking method. The results reveal that LS-TENG achieves a notable power density of 12.2 mW/m2, an output voltage reaching 160 V, and a 98 % output voltage recovery post-low-temperature self-healing. Furthermore, a non-contact LS-TENG-based monitoring system was developed with significant potential for applications in battlefield sensing, wildlife monitoring, and intelligent driving.

Twin-screw extrusion optimization and study of morphological, thermal, mechanical and fracture properties of sustainable Poly(lactic acid) (PLA) and Poly(butylene sebacate) (PBSe) blends

The pursuit of sustainability in material science forces the utilization of bio-based and/or biodegradable alternatives to fossil-based plastics. With growing attention in recent years, particularly in applications like packaging and agriculture, biodegradable and bio-based polymers offer potential solutions to mitigate environmental concerns associated with plastic disposal. In this context, Poly(butylene sebacate) (PBSe), a commercially available biobased and biodegradable aliphatic polyester derived from sebacic acid and 1,4-butandiol, presents a promising innovation due to its flexibility, availability in the market and compatibility with poly(lactic acid) (PLA). Up to day few works investigated the addition of PBSe to PLA, for this reason the present work focuses on comprehensively characterizing PLA/PBSe blends (with different PBSe amounts from 10 up to 40 wt%). The blends have been produced through extrusion compounding after a careful Design of Experiment for optimizing process parameters to efficiently improve mixing and energy consumption. Thermal, mechanical, and morphological properties were evaluated, combined with micromechanical analysis employing dilatometric tests. Additionally, an elasto-plastic fracture mechanics protocol was applied to quantify toughness and energy absorption capabilities, demonstrating the potential of PLA/PBSe blends in sustainable material applications. In this work also emerged the great capacity of PBSe in acting as toughener for PLA especially when is present in low amount.

Secondary Network Formation in Epoxidized Natural Rubber with Alternative Curatives.

Epoxidized natural rubber (ENR) offers a unique combination of strength, sustainability, and versatile structure, making it a good candidate for creating sacrificial and reformable bonds via secondary curatives. These curatives should be simple and compatible with other rubber ingredients and industrial mixing processes. Although many alternative curatives, including zinc chloride, zinc dimethacrylate (ZDMA), and sebacic acid (SA), have been proven to be successful, they have never been compared in the same compound. Moreover, the effectiveness of these alternative curatives on network formation, including their interactions with the other ingredients of a rubber compound, such as fillers, coupling agents, and traditional curatives, has not been fully studied yet. Based on the current study, these secondary curatives alone cannot provide a sufficient level of vulcanization. However, adding ZDMA or SA together with sulfur curatives allowed improving the tensile properties and showed microlevel self-healing behavior during cyclic loading. The addition of 10 phr (parts per hundred rubber) ZnCl2 created weak, short, and rigid bonds in ENR detectable by simple Payne measurements. However, that led to active interaction with all compounding ingredients and deterioration of the physical properties. Reducing the ZnCl2 load to 1 phr allowed full recovery of stress after the cyclic test and fair tensile strength of the compound.

Flame retarded lignin-based epoxy resin with excellent antibacterial and anti-corrosion properties modified by coordinated phospho-nitrogen flame retardant

In this paper, epoxidized lignin (HL) and sebacic acid (HSA) were used as the hard and soft segments, respectively, and a kind of reactive coordinated phosphorous-nitrogen flame retardants (DTZ) was designed and synthesized via Zn2+ coordination to fabricate a multifunctional non-bisphenol A lignin based epoxy (EP) composite. The swelling behavior and morphological analysis demonstrated that the crosslinking density of EP increased significantly after adding HL and DTZ. The existence of coordination sacrificial bond of DTZ dissipated more energy when it was subjected to external forces, thereby making 80HSA/14HL/6DTZ maintained a high tensile strength (10.65 MPa) while having little damage to the elongation at break (30.74 %). The limiting oxygen index (LOI) of 80HSA/14HL/6DTZ was significantly higher than that of 100HSA (22.3 %), reaching 36.6 %, and the vertical combustion test (UL-94) reached V-0 level. The morphology of carbon layer and residual carbon analysis showed that HL and DTZ had synergistic effect, and the flame retardancy mechanism of gas phase and condensed phase existed in the combustion process. Simultaneously, the addition of HL and DTZ also endowed the EP composite with excellent corrosion resistance and antibacterial properties.

Biodegradability of renewable isosorbide and sebacate-based copolyesters

The growing environmental concerns associated with the use of plastics highlight the need to mitigate carbon emissions and environmental pollution via biodegradable plastics development. Herein, biotechnologically accessible and renewable building blocks, namely 1,4-butanediol and sebacic acid, were copolymerized with carbohydrate-derived isosorbide to afford random poly(butylene-co-isosorbide sebacate) with variable isosorbide content. The thermal stabilities of these copolyesters and their biodegradabilities under (non)enzymatic hydrolysis, compost, soil, and marine conditions were examined as functions of isosorbide content. With the increasing isosorbide content, the glass transition temperature increased, whereas the crystallinity and melting temperature decreased. Isosorbide incorporation enhanced hydrolyzability under alkaline and enzymatic conditions, while demonstrating minimal impact under neutral and acidic conditions. The in-compost degradation rate increased with the increasing isosorbide content because of the concomitant decrease in melting temperature and crystallinity. In soil and marine environments, the copolyesters were degraded faster than poly(butylene sebacate). At 30 mol% isosorbide, the degradation extent reached 97.2 and 68.3 % after eight-week degradation in soil and 32-week degradation in a marine environment, respectively. This study is the first to report the biodegradability and degradation mechanisms of poly(butylene-co-isosorbide sebacate) and provides valuable insights into customizing the synthesis of biodegradable plastics to meet the degradation cycle requirements under various environmental conditions.

Optimization of synthesis parameters for polyamide 610: Strategic tailoring for superior latent heat performance

The study systematically optimizes the synthesis of polyamide 610 with the aim of improving latent heat and melting temperature to meet the demanding requirements of high-temperature heat storage applications using Response Surface Methodology (RSM). The results clarify the critical impact of reaction times, washing solvents, and molar ratios on these vital thermal characteristics. Samples exhibiting exceptional latent heat capacities at various mole ratios were further analyzed using Thermogravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FTIR), and X-ray Diffraction (XRD). The TGA assessments were instrumental in determining the thermal degradation behaviors of the materials. At the same time, The DSC analysis was used for the determination of thermal properties of the materials, FTIR provided detailed insights into their molecular structures, and XRD elucidated the crystalline structure of the materials. The findings reveal that a specific mole ratio is essential for achieving superior thermal properties, indicative of the polymer's resilience and structural stability. It was evident that samples with a balanced molar ratio (1:1) and specific reaction time (60 min) showed the best latent heat, surpassing 80 J g-1, and melting temperatures up to 210 °C. A notable aspect of this research is the use of Sebacic Acid instead of the conventional Sebacoyl Chloride for synthesizing polyamide 610. The choice of Sebacic Acid was made due to its lower toxicity and the fact that its byproducts are easier to remove than those from sebacoyl chloride, which produces hydrochloric acid as a byproduct. The presence of HCL can lead to side reactions and negatively impact the reaction process. By using Sebacic Acid, we reduce the risk of such contaminants, thereby enhancing the thermal stability and performance of polyamide 610. This greener approach not only aligns with sustainable practices but also has significant implications for the performance of the polymer. In addition, the integration of RSM with comprehensive characterization techniques has been pivotal in elucidating the critical influence of synthesis parameters on material properties. This enhanced understanding holds the potential for significant contributions to the development of advanced materials for latent heat storage applications, combining sustainability with high performance.

Arthrobotrys oligospora (Fungi: Orbiliales) and its liquid culture filtrate myco-constituents kill Haemonchus contortus infective larvae (Nematoda: trichostrongylidae)

ABSTRACT Arthrobotrys oligospora is a nematode-trapping fungus belonging to the family Orbiliaceae and one of the main antagonists of nematodes in soil, including plant and animal parasitic nematodes and free-living nematodes. This species develops three-dimensional adhesive nets in which nematodes are trapped, destroyed and consumed by the fungus. It also possesses other strategies to immobilise, kill and degrade nematodes, i.e. nematode-attractant substances, cuticle adhesion polymers and a number of nematocidal metabolites. The objective of this study was to assess the in vitro nematocidal activity of a strain of A. oligospora through its predatory activity and its liquid culture filtrates (LCF) against the ruminant parasite Haemonchus contortus (HcL3) and to investigate the presence of myco-compounds with potential nematocidal activity. Predatory activity (PA) was assessed in agar plates; 200 HcL3 were placed on agar plates with the fungus and a control group and incubated for 10 days. The LCF confrontation with nematodes was performed in microtiter plates. Two media, Czapek-Dox Broth (Cz-DB) and potato dextrose broth, were assessed. Three concentrations (25, 50 and 100 mg/mL) were assessed at 48 and 72 h (n = 4, per concentration). The experiment was performed in triplicate. The results showed 73.6 ± 2.7% PA and the highest mortality (83%) with the LCF in Cz-DB after 72 h. Gas chromatography–mass spectrometry (GC–MS) analysis revealed that the A. oligospora ethyl acetate phase was composed of 1,2-benzenedicarboxylic acid, bis (2-methylpropyl) ester, (M) 1,4-benzenedicarboxylic acid, bis (2-methylpropyl) ester and (M) decanedioic acid (2-ethylexyl) ester. These compounds could be responsible for nematocidal activity.

Utilization of modified epoxidized natural rubber and zinc oxide on properties of polylactic acid/epoxidized natural rubber blends: Mechanical properties, antibacterial efficiency and biodegradability

Polylactic acid (PLA) is a biopolymer with brittleness and no antibacterial efficiency, which can be solved by the combination with epoxidized natural rubber (ENR) due to polar-polar interaction and with modified zinc oxide nanoparticles (ZnO) regarding the releasing of zinc ions (Zn2+) and reactive oxygen species (ROS). To minimize self-interaction in each PLA and ENR molecular chain, ENR with different % epoxidation was modified (mENR) by grafting with sebacic acid (SA). The addition of mENR with 50 % mol to PLA significantly improved the properties of pure PLA in terms of mechanical and impact properties, toughness, and also provided disinfectant ability. Regarding antibacterial properties, the efficiency against Staphylococcus aureus and Escherichia coli was significantly improved by adding ZnO to the blends. Combination of mENR to PLA matrix during mixing operation increases improved ZnO dispersion and distribution in PLA/mENR blends. Thus, antibacterial efficiency had been enhanced using proper mENR:ZnO concentration ratios in the PLA matrix, relative to other modified ZnO types. Also, incorporation of mENR:ZnO enhanced impact strength and retarded biodegradability of the blends due to hydrophobicity of ENR in PLA matrix. The findings of the blends' properties suggest potential for new functional applications, especially in disinfectant sheet lamination products where strength and protection against bacterial growth together with proper degradation period are required.

Flexible and recyclable thermally conductive phase change composites with shape stability

AbstractForm‐stable and flexible highly thermally conductive phase change composites are crucial for thermal management. In this work, based on the associative exchangeable crosslinkers derived from the reaction of epoxidized soybean oil (ESO) and sebacic acid (SA), a kind of flexible and recyclable thermally conductive phase change composite with shape stability is prepared. The shape stabilization is achieved through the co‐cooperation of expanded graphite (EG) and the dynamic covalent crosslinking network. The thermal conductivity is enhanced by embedding with boron nitride (BN). When the mass fraction of BN is 25%, the thermal conductivity of the composite can reach 4.03 W/(m·K). The results indicate that the prepared PCMs composites have excellent flexibility and form stability, suggesting the potential application in the thermal management for electronic devices. The presence of dynamic exchangeable bonds makes the matrix degradable under mild conditions, enabling the recycling of valuable thermally conductive fillers, which proves to be highly sustainable. This work introduces a novel method for preparing flexible and recyclable thermally conductive phase change composites with shape stability vitrimer.

HEMP FIBER REINFORCED SUSTAINABLE “GREEN” COMPOSITE PRODUCTION WITH EPOXIDIZED SOYBEAN OIL

Due to the rising environmental concerns, industry branches are pushed to research and invest sustainable materials and technologies. In this context, this study aimed to combine a sustainable fiber and matrix material to produce green composite. For this purpose, epoxidized soybean oil and hemp fiber were utilized for composite production. Sebacic acid and maleic anhydride were used as hardeners. Histidine and glycerol were applied as accelerator and starter, respectively. Mechanical performance of the composites was evaluated by tensile and impact tests. Hemp fiber reinforcement resulted in improvement on tensile properties, up to 2.6 MPa tensile strength and 11.7 kJ/m2 impact strength. Thermal properties were determined by TGA and DSC analyses. The changes in molecular level after curing was traced with FTIR measurements and surface morphology was monitored with SEM imaging.

Epoxy Resins With Controllable "Thermally Conductive-Self-Healing" Synergies: a New Material to Meet the Needs of Flexible Electronic Devices.

With the popularization of 5G technology and artificial intelligence, thermally conductive epoxies with self-healing ability will be widely used in flexible electronic materials. Although many compounds containing both performances have been synthesized, there is little systematic theory to explain the coordination mechanism. In this paper, alkyl chains of different lengths were introduced to epoxies to discuss the thermally conductive, the self-healing performance, and the synergistic effect. A series of electronic-grade biphenyl epoxies (4,4'-bis(oxiran-2-ylmethoxy)-1,1'-biphenyl (1), 4,4'-bis(2-(oxiran-2-yl)ethoxy)-1,1'-biphenyl (2), 4,4'-bis(3-(oxiran-2-yl)propoxy)-1,1'-biphenyl (3), and 4,4'-bis(4-(oxiran-2-yl)butoxy)-1,1'-biphenyl (4) were synthesized and characterized. Furthermore, they were cured with decanedioic acid to produce polymers. Results showed that alkyl chains can both affect the two properties, and the epoxies suitable for specific application scenarios can be prepared by adjusting the length of alkyl chains. In terms of thermal conductivity, compound 1 was a most promising material. However, compound 4 was expected to be utilized in flexible electronic devices because of its acceptable thermal conductivity, self-healing ability, transparency, and flexibility.

Mapping the gut microecological multi-omics signatures to serum metabolome and their impact on cardiometabolic health in elderly adults

Mapping gut microecological features to serum metabolites (SMs) will help identify functional links between gut microbiome and cardiometabolic health. This study encompassed 836-1021 adults over 9.7 year in a cohort, assessing metabolic syndrome (MS), carotid atherosclerotic plaque (CAP), and other metadata triennially. We analyzed mid-term microbial metagenomics, targeted fecal and serum metabolomics, host genetics, and serum proteomics. Gut microbiota and metabolites (GMM) accounted for 15.1% overall variance in 168 SMs, with individual GMM factors explaining 5.65%-10.1%, host genetics 3.23%, and sociodemographic factors 5.95%. Specifically, GMM elucidated 5.5%-49.6% variance in the top 32 GMM-explained SMs. Each 20% increase in the 32 metabolite score(derived from the 32 SMs) correlated with 73% (95% confidence interval [CI]: 53%-95%) and 19% (95% CI: 11%-27%) increases in MS and CAP incidences, respectively. Among the 32 GMM-explained SMs, sebacic acid, indoleacetic acid, and eicosapentaenoic acid were linked to MS or CAP incidence. Serum proteomics revealed certain proteins, particularly the apolipoprotein family, mediated the relationship between GMM-SMs and cardiometabolic risks. This study reveals the significant influence of GMM on SM profiles and illustrates the intricate connections between GMM-explained SMs, serum proteins, and the incidence of MS and CAP, providing insights into the roles of gut dysbiosis in cardiometabolic health via regulating blood metabolites. This study was jointly supported by the National Natural Science Foundation of China, Key Research and Development Program of Guangzhou, 5010 Program for Clinical Research of Sun Yat-sen University, and the 'Pioneer' and 'Leading goose' R&D Program of Zhejiang.

Development and thermal property analysis of biobased binary composite heat storage materials

Natural aliphatic dibasic acids are a type of bio-based material that shows promising potential as green phase change thermal storage materials due to their favorable thermophysical properties. However, these materials have been found to have issues with subcooling, low thermal conductivity, and poor temperature matching. In this study, three aliphatic dibasic acids, namely adipic acid (AA), sebacic acid (SA), and azelaic acid (ZA), were selected for further investigation. Three biobased eutectic systems, AA-SA (melting point: 118.3 °C), ZA-SA (melting point: 96.2 °C), and AA-ZA (melting point: 98.4 °C), were then prepared based on the calculation of Schrader's equation and experimental screening. The eutectic systems were thoroughly characterized, revealing thermal conductivities ranging from 0.4 to 0.5 W·m−1·K−1, with all systems exhibiting a subcooling of around 20 °C. Based on the principle of optimal overall performance, the AA-SA system was selected for modification. By incorporating Expanded graphite (EG) as a highly thermally conductive additive and nucleating agent, the AA-SA/EG composite phase change material (CPCM) was successfully prepared. This modification effectively reduced the supercooling degree of the bio-based phase change materials (PCM) and significantly improved its thermal conductivity by a factor of four. The resulting AA-SA/EG CPCM demonstrated excellent temperature suitability and has the potential to contribute to the application of bio-based phase change materials in waste heat recovery and solar energy systems. This study provides valuable insights into the development and optimization of bio-based phase change materials, contributing to the sustainable utilization of renewable resources for thermal energy storage applications.