PurposeWe report the chances of 14-year-old males becoming victims of firearm injury or death before age 25 in Philadelphia, Pennsylvania. MethodsUsing life table methods, we followed 4,501 Black males aged 14 years, and a comparison group of 1,751 White males, over 11 years. ResultsAmong 14-year-old Black males, the risk of a nonfatal firearm injury before age 25 was 10.1% (95% confidence interval, 9.2%–11.0%), the risk of death from firearms was 2.5% (1.7%–3.2%), and the combined risk was 12.5% (11.0%–14.1%). Among White males, the risk of nonfatal firearm injury was 0.8% (0.3%–1.2%), the risk of death was 0.3% (0.02%–0.5%), and the combined risk was 1.0% (0.5%–1.5%). DiscussionRisk estimates reveal the dire likelihood of firearm injury or death among Black adolescent males in Philadelphia. Immediate interventions are needed to de-escalate conflicts, provide supports, and address the upstream causes of violence like poverty and structural racism.