DDS Technology Research Articles

Design and implementation of a collaborative modeling architecture based on MDE (Multi-DDS Edge)

Abstract Virtual space is an integral part of the Metaverse. Typical virtual spaces are modeled step by step using artificial means. With the development needs of Metaverse modeling and simulation technology and the need for simulation fidelity and content richness in virtual space construction, efficient and correct modeling methods are required. It has become a bottleneck restricting the efficiency of virtual space modeling. This paper designs a multi-person collaborative virtual space modeling method, which improves the modeling efficiency, communication security, and interaction stability of the virtual space collaborative modeling method. Compared with existing collaborative modeling methods, this paper proposes a virtual space collaborative modeling method based on multi-edge DDS technology. By constructing MDE (multi-DDS edges) and MDE on user migration, collaborative construction in multiple virtual spaces is completed. Model data communication extends collaborative modeling technology from the virtual space creation stage to the virtual space simulation and deduction stage, and designs and verifies collaborative content, collaborative architecture, and collaborative communication. Experiments show that the architecture synergy efficiency is 145.6%, the architecture synergy efficiency is 212.5%, and the architecture synergy efficiency is 105.4%. As the number of people in collaborative modeling increases, the operational complexity and demonstration take a logarithmic form, meeting the needs of the future development of the metaverse.

The impact of, and expectations for, lipid nanoparticle technology: From cellular targeting to organelle targeting

The success of mRNA vaccines against COVID-19 has enhanced the potential of lipid nanoparticles (LNPs) as a system for the delivery of mRNA. In this review, we describe our progress using a lipid library to engineer ionizable lipids and promote LNP technology from the viewpoints of safety, controlled biodistribution, and mRNA vaccines. These advancements in LNP technology are applied to cancer immunology, and a potential nano-DDS is constructed to evaluate immune status that is associated with a cancer-immunity cycle that includes the sub-cycles in tumor microenvironments. We also discuss the importance of the delivery of antigens and adjuvants in enhancing the cancer-immunity cycle. Recent progress in NK cell targeting in cancer immunotherapy is also introduced. Finally, the impact of next-generation DDS technology is explained using the MITO-Porter membrane fusion-based delivery system for the organelle targeting of the mitochondria. We introduce a successful example of the MITO-Porter used in a cell therapeutic strategy to treat cardiomyopathy.

Current Status and Prospects of Vaccines based on DDS Technology

Current Status and Prospects of Vaccines based on DDS Technology

Development of Azimycin<sup>Ⓡ</sup> ophthalmic solution 1％ based on ophthalmic DDS technology “DuraSite<sup>Ⓡ</sup>”

アジマイシンⓇ点眼液1％は、アジスロマイシン水和物を有効成分とした日本で唯一のマクロライド系抗生物質点眼液である。アジスロマイシンは良好な組織移行性を示し、酸性pHで安定な特徴をもつ薬物である。また、アジマイシンⓇ点眼液1％の製剤技術には、ポリカルボフィル等を配合した眼科用Drug Delivery System技術のDuraSiteⓇが応用されている。ポリカルボフィルは増粘や粘膜接着性により、眼表面の薬物滞留性および眼内への薬物移行性を向上させることができる。薬物特性や製剤技術により他の抗菌点眼液と比較して､少ない点眼回数で眼感染症の治療が可能であり、患者さんのアドヒアランスの向上が期待できる。

Three-dimensional culture system utilizing DDS technology

Three-dimensional culture system utilizing DDS technology

Sensor Design Based on Wireless Measurement of Corrosion Monitoring of Reinforced Concrete Structure

Reinforced concrete structures are widely used in modern buildings such as buildings, bridges, and tunnels. However, the structural damage caused by reinforcement corrosion seriously affects the service life of the buildings. Because the corrosion of reinforcement in concrete is a very slow process, the continuous detection of reinforcement corrosion is very important. In view of the slow development of steel corrosion detection equipment in China, which cannot meet the application requirements of concrete structures in China, wireless monitoring technology has more advantages than traditional monitoring technology. In this paper, combined with wireless transmission technology, a concrete reinforcement corrosion detection system based on wireless sensor network is designed. Embedded sensors based on the principle of electromagnetic coupling are used to collect steel corrosion information. It is determined that the 16-bit ultralow power consumption microcontroller MSP430F149 is the main control chip, the AD9850 based on DDS technology is the signal generation chip, and the nRF905 is the detection circuit scheme of the wireless transceiver chip. The star network is determined by polling the entire network topology and MAC protocol. The embedded sensor is designed through simulation. This article discusses the principle of using embedded sensors to detect steel corrosion and determines the feasibility of its low-cost implementation. The embedded sensor and steel corrosion detection system were tested. The simulation method of the embedded sensor is verified through actual measurement. The test results show that the system network is normal and all parts work stably, which can meet the requirements of the project.

Design of signal conditioning circuit at the output end of signal source based on AD9954

The signal source based on DDS technology has the characteristics of high precision and high resolution, and is widely used in precision testing, instrumentation and other fields. However, interference signals such as high frequency harmonics and noise will inevitably appear in the output signal of the DDS chip, and even the sinusoidal signal generated by the DDS will be completely covered. This article takes ADI’s 14-bit high-precision DDS chip AD9954 as an example. I/V conversion and elliptic filter circuits are added to the output of the chip to obtain a pure sinusoidal signal. The rationality of the design is verified by multisim simulation software. This circuit provides strong support for the design and implementation of high-precision signal sources based on DDS.

Design of sweep frequency signal source in residual stress detection platform based on Zynq

The signal generator based on DDS technology has high frequency and resolution, and is widely used in many fields such as instrument technology, radar, satellite timing, remote control and telemetry, and is one of the important directions of current signal generator research. In order to achieve a cost-effective, high frequency resolution signal source to stimulate the sensors in the residual stress detection system, this paper selects the Zynq-7020 on-chip system to control the 14-bit direct digital frequency synthesis chip AD9954 to obtain a 40Hz~1MHz sinusoidal signal output. Finally, the performance and technical parameters of the system are tested experimentally. The output signal of the signal source is stable, the signal-to-noise ratio is high, and the frequency error is within 0.1%.

Research and practice of three-phase signal source design based on DDS technology

This paper analyzes the working principle and basic structure of DDS, combined with the design points of three-phase signal source based on DDS technology, including software development platform, hardware description language, sinusoidal signal, AM module, FM module, ASK modulation and demodulation, system assistant, system top, etc. The purpose is to improve the application value of DDS technology and the application effect of three-phase signal source.

OPINION]Evolution of exosome-based DDS technology

OPINION]Evolution of exosome-based DDS technology

The Design of High Precision Arbitrary Waveform Generator Based on DDS Technology and FPGA

Combining with the IP core advantage of FPGA, a signal generator which can generate arbitrary waveform is designed on the basis of direct digital synthesis technology in this paper. The INTEL company’s Cyclone IV series EP4CE6F17C8N is used as the control core and the front-end interface design is carried out by XMAL. The software control operation of the logical processing interface is realized through C#. The signal generator has the characteristics of single cycle waveform with 256 sampling points, clear spectrum analysis, higher purity and high precision. The arbitrary waveform displayed on oscilloscope is wonderful after filtering out high frequency signal by seven order butter worth filter.

Rapid vaccine development, only with the developed DDS technology

Rapid vaccine development, only with the developed DDS technology

Simulation and Design of a Waveform Generator Based on DDS Technology

Simulation and Design of a Waveform Generator Based on DDS Technology

Design of digital detection circuit for signal of helium optical pump magnetometer Summary

Magnetic field measurement technology is an important method to study physical phenomena related to magnetic field. Magnetic field measurement, especially weak magnetic field measurement, often plays a vital role and has important theoretical significance and engineering value for the research of high-performance magnetic field measurement instruments. The helium optical pump magnetometer is a high-precision magnetic measuring device that uses optical pumping and magnetic resonance to realize magnetic field measurement based on the principle of optical magnetic resonance. It has the advantages of low noise, wide measurement range, and low temperature working environment. It has significant advantages in the field of weak magnetic field measurement and can be widely used in scientific research, national defense construction, industrial production, daily life and other fields. The traditional detection circuit is based on a voltage-controlled oscillator as the core and an analog circuit-based detection system. The modulation signal is used for magnetic field detection. The detection speed is slow, and the modulated signal will superimpose an interfering magnetic field on the probe, affecting the measurement result. This paper designs a digital detection system with DDS technology as the core, which greatly improves the speed of detecting the magnetic field. A new swingswing frequency method is used to avoid the interference of the modulation coil, and a breakthrough in detection speed is achieved, reaching a sampling frequency of 20Hz. To meet the requirements of a system that requires continuous measurement at a faster rate.

The new state measurement standard of the unit of frequency deviation of frequency-modulated oscillations

The article is devoted to the review of the main results of research and development works performed during the improvement of the state primary measurement standard of the frequency deviation unit. The article analyzes the situation in the field of measuring the parameters of frequency-modulated oscillations in Ukraine that led to the need for improving the unit of frequency deviation created in 1996, namely the need to significantly enhance metrological characteristics and expand the functionality of the measurement standard.Тhe principle of building a modern measurement standard with advanced functionality, improved metrological characteristics was developed. Solutions used the modern hardware level for measuring parameters of oscillations with frequency modulation and expanding modulating frequencies and deviations.In the measurement standard, the role of the reference receiver is performed by the spectrum analyzer, which implements the method of measuring the deviation of the Bessel function “zeros” (NFB). The second method used in the measurement standard is a digital method known as the “electronic counting frequency meter” (ELC) method. One of the comprehensive decisions was the use of digital signal generators, which are based on DDS technology (direct digital synthesis) and its subsequent version – Trueform. The article presents the results of analysis of metrological capabilities of these generators in the FM mode, original methods of their research and new results obtained.During the improvement, the method of receiving the FM signal, based on the use of a spectrum analyzer and an option, analog-digital demodulator, was used and investigated. Automation of control and computational operations on the measurement standard on the basis of the Labview program was carried out.As a result, a reference complex was created, which according to its metrological characteristics and functional capabilities is able to calibrate not only the devices in the FM mode, but also a wide range of radio measuring instruments of both receiving and generating types.

Method Research and Realization of Noise FM Jamming Based on DDS Technology

Noise FM jamming which has wide jamming band and large noise power is widely used in processing backup jamming to radar, fuze and communication. The paper adopt DDS combines with characteristic of FPGA chip to generate noise FM jamming. The method has large improvement in precision, structure and speed, and has broad application and prospect.

Development of cancer immunotherapy based on nano DDS technology：11<sup>th</sup> Young Scientist Award, Japan Society of DDS

Development of cancer immunotherapy based on nano DDS technology：11<sup>th</sup> Young Scientist Award, Japan Society of DDS

DDS技術を活用した体内再生誘導治療

体内に存在する組織幹細胞の研究が進み、それを用いた再生医療の開発が期待されている。内在性幹細胞を利用することができれば低コストで安全な治療が可能になると考えられるが、その実現のためには再生能力を促進する技術が必要である。内在性幹細胞の分化・誘導因子を局所に供給するドラッグデリバリー技術の有効性が種々の研究によって明らかにされ、臨床応用がなされているものもある。こうした取り組みの現状を紹介する。

OPINION] アカデミア発DDS技術の実用化

OPINION] アカデミア発DDS技術の実用化

DDS technology of nano/micro particles and clinical application

DDS technology of nano/micro particles and clinical application