This paper will focus on techniques used in patients monitoring in healthcare based on medical images. Lossless coding algorithm, watermark compression (add safety to data), GLCM, Huffman coding, LZW, DCT and soft compression techniques are used for efficient image compression. Lossless coding algorithms helps to reduce image size without losing the data. An image watermarking secret key (ROI) is used in this research to create a watermark that is unique to each picture. By comparing LZW compression with traditional approaches, it was observed that the LZW methodology has better performance than others.