ABSTRACT Flooding in remote regions presents significant challenges due to data scarcity, complicating impact assessment and mitigation efforts. This research delineates an integrated methodology for quantifying flood impacts in such contexts. By leveraging machine-learning algorithms, Sentinel-1 synthetic aperture radar (SAR) imagery was combined with digital elevation model data and river proximity metrics to predict and accurately demarcate flood extents. Geographic information systems overlay techniques were then employed for spatial analysis of the floods’ impacts on population and infrastructural assets. The methodology was applied in a case study in Ngabang District, Indonesia, demonstrating its utility. Analysis using decision tree, random forest (RF), and gradient boosting machine models provided critical insights into flood prediction factors. The RF model was chosen as the best, successfully identified flood-prone regions, achieving an accuracy of 0.94 and a Kappa of 0.87 on the testing data, demonstrating its robustness. The flood map showed significant impacts, affecting 373.81 hectares, 10,706 people, 1,500 buildings, and 15 km of roads. This study highlights the importance of proximity, elevation, SAR imagery, and iterative model improvements in flood prediction, offering valuable insights for flood management and mitigation efforts in data-scarce regions.