ABSTRACT A hippopotamus and other wildlife species survey were conducted in the Zambezi River between Kariba dam wall and Luangwa River confluence. The main objective of the survey was to establish hippopotamus and other wildlife species population distribution and densities along the Zambezi River. The boat survey method was used on both sides of the river in October 2022 for 262 km. Individual hippopotamus counted were 1769 on the Zambian side and 1424 on the Zimbabwean side. The Zimbabwean side recorded higher hippopotamus pods (138) than the Zambian side (123). Individual hippopotamus density was 26.60/km with a pod density of 0,45/km. There was a significant difference in hippo population between the five Zambezi River sections on the Zambian side ( x 2 = 2345, df = 4, p = 0.01) and Zimbabwean side ( x 2 = 538, df = 4, p = 0.01). The study established areas with high hippo and other wildlife species population distribution and densities, and the study helps to inform management of protected areas’ carrying capacities and management of Human Wildlife Conflicts. The study recommends more studies on hippopotamus migration, population demography, variation in home ranges and regular population surveys in both rivers and inland waterholes.