This study investigates the carbon dioxide (CO2) emissions generated by transportation and power generation in Duhok Governorate, Kurdistan Region of Iraq. The research highlights the alarming levels of CO2 emissions resulting from the region's 270,315 vehicles and 1,814 private electric power generators, which consume approximately 1,500,000 liters of gasoline and 650,000 liters of diesel daily. These activities contribute to a total daily CO2 emission of 1,741,188 kg, amounting to over 626,827,680 kg annually. The findings reveal the significant environmental and public health threats posed by these emissions, emphasizing the urgent need for targeted mitigation strategies. Comparisons with other urban regions such as Cairo, Tehran, New Delhi, Lagos, and Nairobi reveal a similar pattern of high vehicular and generator-induced CO2 emissions, underscoring the global nature of this environmental challenge. The study underscores the importance of addressing CO2 emissions through improved regulations, modernized infrastructure, and sustainable energy practices to protect both the environment and public health.