Customizable Forms Research Articles

Advancing Bioactive Material for Mandibular Bone Regeneration: Transformation of Fibrous Mat into 3D Matrix Cotton for Enhanced Shape Retention and Rapid Hemostasis.

Transformation of a fibrous mat into a three-dimensional (3D) scaffold opens up abundant innovative prospects in biomedical research, particularly for studying both soft as well as hard tissues. Electrospun nanofibers, which mimic the extracellular matrix have attracted significant attention in various studies. This research focuses on rapidly converting a fibrous mat made of polycaprolactone (PCL)/pluronic F-127 (PF-127) with different percentages of monetite calcium phosphate (MCP) into desirable 3D matrix cotton using a unique gas foaming technology. These matrix cottons possess biomimetic properties and have oriented porous structures. Using this innovative technique, various shapes of 3D matrix cotton, such as squares, hollow tubes, and other customizable forms, were successfully produced. Importantly, these 3D matrix cottons showed a consistent distribution of monetite particles with total porosity ranging from 90% to 98%. The structure of the 3D matrix cotton, its water/blood absorption capacity, the potential for causing non-hemolysis, and rapid hemostatic properties were thoroughly investigated. Additionally, periodontal cells were cultured on the 3D matrix cotton to assess their viability and morphology, revealing promising results. Furthermore, a coculture study involving NIH-3T3 and MG-63 cells on the 3D matrix cotton showed spheroidal formation within 24 h. Notably, in vitro assessments indicated that the matrix cotton containing 15% monetite (PCL-MMC15%) exhibited superior absorbent capabilities, excellent cell viability, and rapid hemostatic characteristics. Subsequently, the effectiveness of PCL-MMC15% in promoting mandibular bone regeneration was evaluated through an in vivo study on rabbits using a mandibular injury model. The results demonstrated that PCL-MMC15% facilitated the resolution of defects in the mandibular region by initiating new bone formation. Therefore, the presented 3D matrix cotton (PCL-MMC15%) shows significant promise for applications in both mandibular bone regeneration and hemostasis.

Electronic occurrence variance reporting system: A reliable multi-platform system for the low-income settings

BackgroundReducing waste, improving quality, boosting treatment efficacy, and providing safe patient-centered health care are the top priorities for most healthcare organizations. A reliable incident reporting system is a method that can help decision-makers stay aware of any incidents that violate patient safety guidelines, examine the probable causes, and come up with new policies that can prevent future patient safety violations. MethodsIn this study, we present our newly developed electronic Occurrence Variance Reporting system (eOVR), made specifically for low-income countries with a cost as low as 5 USD/month, along with the steps required for the reporting and the potential benefits to the whole healthcare system. This system was developed using a third-party application, AppSheet, which provides already established customizable forms that would help any hospital to develop its reporting system without the need for programming experts or the expensive infrastructure needed for it. ResultsOur system is composed of three main stages that allow the participating members to report, taking a decision, and evaluating the need for further actions. We implemented a mixture of electronic tools designed to fulfill the purpose of reporting incidents and facilitating the analysis of the system gaps, especially in times of crisis using an incident report that can be generated automatically and immediately using this system. ConclusionTo the best of our knowledge, this is the first electronic model of OVR developed to be used in individual hospitals in low-income countries without the need for expensive infrastructure or hiring a professional programmer. This model could save time and offer more flexibility and versatility to both the incident reporter and the decision-makers. Lastly, offering a low-cost solution, as low as 5 USD/month, would encourage the hospitals to participate in incident reporting, as well as enhance the digitalization process in low-income countries.

The Efficacy of Using a Browser‐Based Evidence Management System for Anatomical Donation Program Administration

Anatomical donation programs require extensive and detailed record keeping to properly manage each donor's sensitive personal and medical information, cadaver storage and usage histories, communications with potential donors and their families, and information concerning arrangements for remains once the donation term has ended. The aim of this presentation is to describe the adaptation and use of the SAFE© (Shared Archive For Evidence) browser-based evidence management system by Tracker Products, LLC for an anatomical donation program. SAFE© provides customizable forms and reports, stores all information related to current and future donors, allows user-specific access to donor information from anywhere, and provides quality assurance tools for more accurate donor management. Prior to use of the SAFE© system, the WMed Body Donation program relied on multiple spreadsheets, online databases, local storage, and “fill-in-the-blank” forms for donation management. SAFE©’s form and report building tools allow for customization of the database to accommodate gathering, storing, and generating quick reports on a variety of information types.Thespecific protocol is as follows. A case is created in SAFE© when an individual contacts the program expressing interest in donation. This case can be updated once registration is complete and when the individual enters the donation program to reflect each stage of the donation process. Personal history, medical records and imaging, prosections, cadaver condition, and more can all be tracked and managed in a single location. A benefit of using a browser-based system, like SAFE©, is the ability to access donor information from anywhere as opposed to relying on virtual private network (VPN) connections to secure institutional networks. The free mobile application is especially useful as it allows anatomy laboratory staff to quickly access information regarding a donor's medical history and prosections completed on a donor. This secure access to information allows for structures of interest to be found quickly and for a connection between anatomical structure and clinical significance to occur as students are engaging in lab. The SAFE© system allows for more accurate donation and lab management through discrepancy reports, system and case audits, and barcode scanning tracking capabilities. These features ensure donations are used appropriately and are accounted for at all times, even when donated materials may be stored in different locations or institutions. Overall, the use of a single browser-based system has significantly improved donor use and management within the WMed Body Donation Program. Utilization of this program has also positively impacted anatomical education at WMed. Storing information about prosections, structures of interest, and the medical history of each donor in one secure program allows laboratory staff to prepare and conduct labs efficiently. Having quick secure access to donor medical histories allows students to consider a donor's anatomy not simply scientifically but also clinically. Thus, students can connect clinical knowledge learned in the classroom with structures of the body to which it pertains.

Integration of a Zero-footprint Cloud-based Picture Archiving and Communication System with Customizable Forms for Radiology Research and Education

The purpose of this study was to integrate web-based forms with a zero-footprint cloud-based Picture Archiving and Communication Systems (PACS) to create a tool of potential benefit to radiology research and education. Web-based forms were created with a front-end and back-end architecture utilizing common programming languages including Vue.js, Node.js and MongoDB, and integrated into an existing zero-footprint cloud-based PACS. The web-based forms application can be accessed in any modern internet browser on desktop or mobile devices and allows the creation of customizable forms consisting of a variety of questions types. Each form can be linked to an individual DICOM examination or a collection of DICOM examinations. Several uses are demonstrated through a series of case studies, including implementation of a research platform for multi-reader multi-case (MRMC) studies and other imaging research, and creation of an online Objective Structure Clinical Examination (OSCE) and an educational case file.

Chemically Active, Porous 3D-Printed Thermoplastic Composites.

Metal-organic frameworks (MOFs) exhibit exceptional properties and are widely investigated because of their structural and functional versatility relevant to catalysis, separations, and sensing applications. However, their commercial or large-scale application is often limited by their powder forms which make integration into devices challenging. Here, we report the production of MOF-thermoplastic polymer composites in well-defined and customizable forms and with complex internal structural features accessed via a standard three-dimensional (3D) printer. MOFs (zeolitic imidazolate framework; ZIF-8) were incorporated homogeneously into both poly(lactic acid) (PLA) and thermoplastic polyurethane (TPU) matrices at high loadings (up to 50% by mass), extruded into filaments, and utilized for on-demand access to 3D structures by fused deposition modeling. Printed, rigid PLA/MOF composites display a large surface area (SAavg = 531 m2 g-1) and hierarchical pore features, whereas flexible TPU/MOF composites achieve a high surface area (SAavg = 706 m2 g-1) by employing a simple method developed to expose obstructed micropores postprinting. Critically, embedded particles in the plastic matrices retain their ability to participate in chemical interactions characteristic of the parent framework. The fabrication strategies were extended to other MOFs and illustrate the potential of 3D printing to create unique porous and high surface area chemically active structures.

Shape‐Customizable Macro‐/Microporous Carbon Monoliths for Structure‐to‐Functionality CO2 Adsorption and Novel Electrical Regeneration

AbstractPotential of porous carbons for practical applications is often limited by their intrinsic fragility and poor processability. Here, a facile approach to fabricate hierarchically macro‐/microporous carbon monolith (CM) with high strength and integrated structure is developed, which offers great possibilities for structure‐to‐functionality applications. Through a fiber‐reinforced sol–gel process and an ambient pressure drying approach, aerogel‐like CMs can be designed and fabricated in customizable forms. In particular, a novel scroll‐type carbon monolith (S‐CM) is constructed, which can mimic a roll‐to‐roll tube reactor and thus avoid the packing problems arising from the granules or powders of conventional activated carbons. The resulting CM exhibits a high CO2 adsorption capacity of 15.9 mmol g−1 at 25 bar and a breakthrough capacity of 1 mmol g−1 at 1 bar. Moreover, owing to the integrated structure and good electrical conductivity, the scroll‐type S‐CM can be easily regenerated by employing a low‐energy electrothermal desorption technique. The specialized design of the CMs should fulfill industrial directives and may provide an access route to more efficient porous carbons for structure‐oriented and process‐intensified applications.

XMPP Based Applications under Low Bandwidth and High Latency Conditions

This paper discusses use of Extensible Messaging and Presence Protocol (XMPP) based applications under Low Bandwidth and High Latency conditions. Such conditions usually occur during communication between air-to-air or air-to-distant sea platforms. Considering the type of subject conditions XMPP applications discussed in this paper is mostly applicable to military and defense industry. In terms of XMPP applications IM, chat, message broadcasting, Customizable Forms (CF), archiving and database functionalities can be considered. Conditions of Low Bandwidth and High Latency require existing XMPP and data exchange mechanism to be revised or simplified. Otherwise XMPP communication is delayed or gets interrupted and the purpose of XMPP application is not properly met. This study discusses the use of compression algorithms to tackle this problem. Although quantitative facts are provided and referenced this paper is based on empirical approach and includes qualitative results.