To foster innovation and entrepreneurship education, Zhanjiang University of Science and Technology aims to integrate it with professional education, discipline competitions, scientific and technological innovation, ideological and political education, as well as labor education. This integration will create a distinctive 'Five Innovation and Integration' model for talent development that enhances students' comprehensive abilities in innovation and entrepreneurship. This paper combines the concepts of ' the integration of specialty and innovation ' along with ' the integration of competition and innovation' through the establishment of a practical teaching base to facilitate the training of applied innovation and entrepreneurship talents[1]. The construction objectives of Zhanjiang University of Science and Technology-Xingyang Industry practical teaching base are introduced, along with its operational framework encompassing curriculum internship, graduation internship, and discipline competitions. Finally, this paper summarizes the achievements made in constructing the practical teaching base while aiming to provide a solid foundation for cultivating applied innovation and entrepreneurship talents at our institution.