Current Set Of Studies Research Articles

The effect of emotional prosody and referent characteristics on novel noun learning

Abstract Prosody includes the pitch, timing and loudness in speech, which can convey meaning and emotion. This study examines whether prosodic categories affect novel noun learning and whether the referent characteristic influence learning. Previous research showed that emotional prosody interfered with adults’ noun learning (West et al., 2017), but it had no effect on children (West et al., 2022). However, these researchers varied their method across ages, including animacy and complexity of the referent, and it is unclear if the results extend beyond the three emotional prosodies tested. Participants in the current set of studies heard novel words presented in five prosodic categories (within-subject) in order to learn the label for either animate or inanimate objects (between-subject). Study 1 compared inanimate objects and aliens, with better noun learning performance for inanimate objects. Study 2 compared inanimate objects with the same objects with faces added, but there was no difference in noun learning by object type. Both studies showed differences in noun learning by the prosodic category, with warning less accurate than naming. These results demonstrate how extralinguistic factors like prosody, attention and referent complexity influence noun learning.

Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder.

Alcohol use disorder (AUD) is a chronic, relapsing disorder characterized by an escalation of drinking and the emergence of negative affective states over time. Within this framework, alcohol may be used in excessive amounts to alleviate withdrawal-related symptoms, such as hyperalgesia. Future effective therapeutics for AUD may need to exhibit the ability to reduce drinking as well as to alleviate co-morbid conditions such as pain, and to take mechanistic sex differences into consideration. Agmatine is an endogenous neuromodulator that has been previously implicated in the regulation of reward and pain processing. In the current set of studies, we examined the ability of agmatine to reduce escalated ethanol drinking in complementary models of AUD where adult male and female mice and rats were made dependent via chronic, intermittent ethanol vapor exposure (CIE). We also examined the ability of agmatine to modify thermal and mechanical sensitivity in alcohol-dependent male and female rats. Agmatine reduced alcohol drinking in a dose-dependent fashion, with somewhat greater selectivity in alcohol-dependent female mice (versus non-dependent female mice), but equivalent efficacy across male mice and both groups of male and female rats. In mice and female rats, this efficacy did not extend to sucrose drinking, indicating some selectivity for ethanol reinforcement. Female rats made dependent on alcohol demonstrated significant hyperalgesia symptoms, and agmatine produced dose-dependent antinociceptive effects across both sexes. While additional mechanistic studies into agmatine are necessary, these findings support the broad-based efficacy of agmatine to treat co-morbid excessive drinking and pain symptoms in the context of AUD.

Oy Vey, the Shtick: Exploring the Relationship between Audience Consumption of Jewish Television Characters and Attitudes toward Jewish Populations

The current set of studies adopts cultivation theory and mediated contact to explore the relationship between viewers’ consumption of Jewish television characters, endorsement of negative Jewish stereotypes (study 1; N = 150), anti-Semitism, and support for Jewish-related social issues (study 2; N = 584). Study 1 revealed a significant relationship between viewers’ consumption of Jewish television characters and Jewish stereotype endorsement. Study 2 showed a significant relationship between viewers’ consumption of Jewish television characters and anti-Semitic attitudes; however, consumption was also related to viewers’ favorable support for Jewish-related social issues. Findings indicate a complicated relationship and suggest that the consumption of Jewish television characters may intensify negative attitudes, including stereotype endorsement and anti-Semitism, but the ethnic and cultural identity contributes to confounding feelings toward social issues. We offer a discussion of the results regarding media cultivation, intergroup contact, and the Jewish community.

Testing locus coeruleus-norepinephrine accounts of working memory, attention control, and fluid intelligence.

The current set of studies examined the relationship among workingmemory capacity, attention control, fluid intelligence, and pupillary correlates of tonic arousal regulation and phasic responsiveness in a combined sample of more than 1,000 participants in two different age ranges (young adults and adolescents). Each study was designed to test predictions made by two recent theories regarding the role of the locus coeruleus-norepinephrine (LC-NE) system in determining individual differences in cognitive ability. The first theory, proposed by Unsworth and Robison (2017a), posits two important individual differences: the moment-to-moment regulation of tonic arousal, and the phasic responsiveness of the system to goal-relevant stimuli. The second theory, proposed by Tsukahara and Engle (2021a), argues that people with higher cognitive abilities have greater functional connectivity between the LC-NE system and cortical networks at rest. These two theories are not mutually exclusive, but they make different predictions. Overall, we found no evidence consistent with a resting-state theory. However, phasic responsiveness was consistently correlated with working memory capacity, attention control, and fluid intelligence, supporting a prediction made by Unsworth and Robison (2017a). Tonic arousal regulation was not correlated with working memory or fluid intelligence and was inconsistently correlated with attention control, which offers only partial support for Unsworth and Robison's (2017a) second prediction.

"The many faces of sorrow": An empirical exploration of the psychological plurality of sadness.

Sadness has typically been associated with failure, defeat and loss, but it has also been suggested that sadness facilitates positive and restructuring emotional changes. This suggests that sadness is a multi-faceted emotion. This supports the idea that there might in fact be different facets of sadness that can be distinguished psychologically and physiologically. In the current set of studies, we explored this hypothesis. In a first stage, participants were asked to select sad emotional faces and scene stimuli either characterized or not by a key suggested sadness-related characteristic: loneliness or melancholy or misery or bereavement or despair. In a second stage, another set of participants was presented with the selected emotional faces and scene stimuli. They were assessed for differences in emotional, physiological and facial-expressive responses. The results showed that sad faces involving melancholy, misery, bereavement and despair were experienced as conferring dissociable physiological characteristics. Critical findings, in a final exploratory design, in a third stage, showed that a new set of participants could match emotional scenes to emotional faces with the same sadness-related characteristic with close to perfect precision performance. These findings suggest that melancholy, misery, bereavement and despair can be distinguishable emotional states associated with sadness.

Chronic lipopolysaccharide impairs motivation when delivered to the ventricles, but not when delivered peripherally in male rats

Increased neuroinflammation relative to controls is observed in major depression. Moreover, depressive disorders are significantly elevated in conditions which increase neuroinflammation (e.g., brain injury, Parkinson's disease, Alzheimer's disease). To better understand the relationship between neuroinflammation and depression, additional research is needed. The current set of studies made use of the progressive ratio (PR) task in male rats, a stable measure of motivation which can be evaluated daily and thus is ideally suited for examining a potential role for chronic neuroinflammation in depressive-like behavior. Lipopolysaccharide (LPS) was used to induce an inflammatory response. Experiment 1 confirmed prior acute LPS administration experiments for sensitivity of the PR task, with a large effect at 2 mg/kg, a partial effect at 1 mg/kg, and no effect at 0.5 mg/kg. Experiment 2 evaluated a dose-response of continuous s.c. LPS infusion but found no significant elevation in brain cytokines after 14 days at any doses of 0.1, 0.5, 1, or 2 mg/kg/week. Experiment 3 assessed motivation during continuous s.c. infusion of a large 5 mg/kg/week LPS dose and found no significant impairments in motivation, but transient decreases in rates of lever pressing (i.e., only motoric deficits). Experiment 4 measured motivation during continuous ICV infusion of 10.5 μg/kg/week LPS and found significantly decreased motivation without changes to rates of lever pressing (i.e., only motivational deficits). Together these results suggest that the PR task is efficient for evaluating models of chronic inflammation, and that the adaptive response to chronic LPS exposure, even when delivered centrally, may necessitate alternative strategies for generating long-term neuroinflammation.

How do children overcome their pragmatic performance problems in the true belief task? The role of advanced pragmatics and higher-order theory of mind.

The true belief (TB) control condition of the classical location-change task asks children to ascribe a veridical belief to an agent to predict her action (analog to the false belief (FB) condition to test Theory of Mind (ToM) abilities). Studies that administered TB tasks to a broad age range of children yielded surprising findings of a U-shaped performance curve in this seemingly trivial task. Children before age four perform competently in the TB condition. Children who begin to solve the FB condition at age four, however, fail the TB condition and only from around age 10, children succeed again. New evidence suggests that the decline in performance around age four reflects pragmatic confusions caused by the triviality of the task rather than real competence deficits in ToM. Based on these results, it can be hypothesized that the recovery of performance at the end of the U-shaped curve reflects underlying developments in children's growing pragmatic awareness. The aim of the current set of studies, therefore, was to test whether the developmental change at the end of the U-shaped performance curve can be explained by changes in children's pragmatic understanding and by more general underlying developmental changes in recursive ToM or recursive thinking in general. Results from Study 1 (N = 81, 6-10 years) suggest that children's recursive ToM, but not their advanced pragmatic understanding or general recursive thinking abilities predict their TB performance. However, this relationship could not be replicated in Study 2 (N = 87, 6-10 years) and Study 3 (N = 64, 6-10 years) in which neither recursive ToM nor advanced pragmatic understanding or recursive thinking explained children's performance in the TB task. The studies therefore remain inconclusive regarding explanations for the end of the U-shaped performance curve. Future research needs to investigate potential pragmatic and general cognitive foundations of this developmental change more thoroughly.

An implicit leadership theory lens on leader humility and employee outcomes: Examining individual and organizational contingencies

An emerging leadership style centered on the moral practice of humility has recently garnered the attention of organizational researchers in the hospitality field. Taken in tandem with the prevailing empirical evidence supporting the various salutary effects of leader humility on employees' job attitudes and moral behaviors, the current set of studies offers an implicit theoretical perspective on leadership that underlines the importance of identifying both individual characteristics and organizational factors that can alter employees' assessments of humble leaders. We propose that employees' assessments of humble leaders' benevolence hinge on the employees' learning goal orientations and their perceptions of informational justice in the workplace. The results of two multi-wave field studies indicate perceptions of humble leaders' benevolence are significantly more favorable among employees who have strong learning goal orientations and high perceptions of informational justice. Employees' perceptions of leader benevolence are, in turn, positively associated with the employees’ affective commitment.

Repeat Closed-Head Injury in Male Rats Impairs Attention but Causes Heterogeneous Outcomes in Multiple Measures of Impulsivity and Glial Pathology.

Repetitive mild traumatic brain injury, or concussion, can lead to the development of long-term psychiatric impairments. However, modeling these deficits is challenging in animal models and necessitates sophisticated behavioral approaches. The current set of studies were designed to evaluate whether a rubberized versus metal impact tip would cause functional deficits, the number of injuries required to generate such deficits, and whether different psychiatric domains would be affected. Across two studies, male rats were trained in either the 5-choice serial reaction time task (5CSRT; Experiment 1) to assess attention and motor impulsivity or concurrently on the 5CSRT and the delay discounting task (Experiment 2) to also assess choice impulsivity. After behavior was stable, brain injuries were delivered with the Closed-head Injury Model of Engineered Rotational Acceleration (CHIMERA) either once per week or twice per week (Experiment 1) or just once per week (Experiment 2). Astrocyte and microglia pathology was also assayed in relevant regions of interest. CHIMERA injury caused attentional deficits across both experiments, but only increased motor impulsivity in Experiment 1. Surprisingly, choice impulsivity was actually reduced on the Delay Discounting Task after repeat injuries. However, subsequent analyses suggested potential visual issues which could alter interpretation of these and attentional data. Subtle changes in glial pathology immediately after the injury (Experiment 1) were attenuated after 4 weeks recovery (Experiment 2). Given the heterogenous findings between experiments, additional research is needed to determine the root causes of psychiatric disturbances which may arise as a results of repeated brain injuries.

Method development for the analysis of PBMC-mediated killing of K562 cells by bovine colostrum

BackgroundColostrum is the first milk that supplies newborns with immune supporting peptides. Due to its heterogeneous and variable characteristics, standardized assays for assessment of its biological activities are a challenge. The current set of studies were aimed to investigate the immune activity of bovine colostrum blends as well as develop a method to assess variability across different lots. MethodsImmune activity of a bovine colostrum blend was evaluated by their ability to enhance PBMC (peripheral blood mononuclear cell)-mediated killing of K562 cells. K562 cell killing was assessed by flow cytometry using DAPI. PBMCs derived from multiple healthy donors were initially investigated. Frozen PBMC aliquots from one of the highest responders were used for subsequent studies. Different doses and lots of product were assessed. Incubation time was also explored. ResultsBovine colostrum blend similarly reduced K562 cells number and these effects were often greater than the IL-2 positive control. Despite consistent efficacy at enhancing PBMCs-mediated K562 killing, the degree of the effect was significantly variable across different lots. These biological effects were largely dependent on the solubility of the product. ConclusionAssessment of PBMC-mediated killing of K562 cells by flow cytometry using DAPI can be a reliable method for measuring immune activity of bovine colostrum when the material is well-dissolved into solution and the same biological sample from a single donor is used.

Observer reactions to workplace mistreatment: It's a matter of perspective.

Workplace mistreatment regularly occurs in the presence of others (i.e., observers). The reactions of observers toward those involved in the mistreatment episode have wide-reaching implications. In the current set of studies, we draw on theories of perspective-taking to consider how this form of interpersonal sensemaking influences observer reactions toward those involved in a witnessed incident of workplace mistreatment. We find that observers' blame attributions and empathic concern for the individual whose perspective is taken explain the positive effects of perspective-taking on observer attitudes toward and performance evaluations of both the target and instigator of a witnessed incident of mistreatment. We also find that the effect of perspective-taking on observer reactions is stronger when the witnessed mistreatment is more severe. Finally, we find that although observer perspective-taking in the context of mistreatment can be encouraged, the effect seems to benefit instigators' performance evaluations rather than targets'. Implications for targets, instigators, and organizations are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Smartphone display size can influence perceptual judgments

Classic research in perception has suggested that visual context can impact how individuals perceive object characteristics like physical size. The current set of studies extends this work to an applied setting by examining whether smartphone display size can impact the perception of objects presented on smartphones. Participants viewed several target items, on two different sized virtual device displays based on actual consumer devices and were asked to make simple judgments of the size of presented objects. Results from both experiments confirm that display size impacts perceived size, such that larger displays cause users to significantly underestimate the size of objects moreso than smaller displays. This is the first study to confirm such an effect, and suggests that beyond aesthetics or cost, one’s personal choice of device might have additional performance consequences.

Small procedural differences matter: Conceptual and direct replication attempts of the communication-intervention effect on infants’ false-belief ascriptions

The current replication crisis in experimental psychology has called into question findings regarding infants’ early false-belief understanding. It is, however, debated whether non-replications might be due to procedural differences between replication attempts and original studies. The current set of studies aimed to shed light on this question by trying to replicate a violation-of-expectation study by Song, Onishi, Baillargeon and Fisher (2008). This task seemed especially important since it addresses not only the question whether or not infants hold false-belief assumptions but also whether they update these assumptions given informative (but not uninformative) verbal input. Studies 1a and 1b failed to replicate the original findings conceptually. Study 2 – which included 10-second-delays as did the original study – also failed to fully replicate the original pattern of results. More specifically, informative as well as uninformative statements elicited the communication-intervention effect. The fact that this effect appeared only when using the exact same procedure as the original study suggests that subtle features of a test procedure might influence infants’ performance in an implicit false belief task. However, the failure to fully replicate the original pattern of results emphasizes that even direct replications do not necessarily result in a successful replication.

Development and psychometric evaluation of the Caffeinated Alcoholic Beverages Motives Questionnaire.

Caffeinated alcoholic beverage (CAB) consumption is a risky drinking practice for young people. The purpose of the current set of studies was to develop and psychometrically evaluate a theory-based CAB motives measure to understand what drives CAB consumption and its ensuing consequences. Using 4 different samples, we pilot tested the items of the Caffeinated Alcohol Beverages Motives Questionnaire (CABMQ) and then evaluated its factor structure and its convergent, concurrent, and discriminant validity. Factor analyses supported a 5-factor structure. The coping and conformity subscales assessed negative reinforcement from internal and external sources, respectively. The social subscale assessed positive reinforcement derived from external sources, whereas the intoxication and energy enhancement subscales assessed positive reinforcement derived from internal sources. Differential relationships between the intoxication and energy enhancement subscales and existing motives measures provided compelling support for their individual distinctiveness. Greater endorsement of all subscales was related to experiencing more adverse alcohol-related consequences, whereas all subscales but the conformity subscale were related to greater CAB consumption. After controlling for general drinking motives, coping motives, energy enhancement motives, intoxication enhancement motives, and social motives were significantly correlated with CAB use, whereas only energy enhancement motives were significantly correlated with alcohol-related consequences. In sum, these results show that the CABMQ helps us understand CAB use and its consequences, with the energy enhancement subscale being particularly helpful. Future research should examine if energy enhancement motives explain why CABs pose more risk than drinking alcohol on its own. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Positive Solitude Scale: Theoretical Background, Development and Validation

The current set of studies was aimed at examining the theoretical basis, development process, and psychometric properties of a new scale for measuring positive solitude (PS). The theoretical idea behind the development of this construct was to develop a stand-alone scale for measuring the positive aspects of an individual's ability to volitionally choose to spend time by him/herself. Using five different samples, we examined the face validity, exploratory/confirmatory factor analysis results, construct validity, and test–retest reliability of the new scale. The results were replicated across five studies, demonstrating a single factor for the 9-item PS scale which had good convergent and divergent validity and acceptable test–retest reliability. Overall, this new short scale has excellent psychometric properties. This scale may serve as a tool for further examining the phenomenon of PS, a concept that is under-developed in the psychological literature. PS can also be perceived as an important personal asset, when other personal resources may be depleted. A better understanding of the PS phenomenon may thus enhance development of interventions aimed at improving this ability. PS may be especially important for older adults, who sometimes face challenges with engaging in varied social activities and need to cope with more time alone.

Hope and well-being in vulnerable contexts during the COVID-19 pandemic: does religious coping matter?

ABSTRACT To identify potential protective mechanisms that might buffer the effects of the COVID-19 pandemic on well-being, the current set of studies (N Study 1 = 1172, N Study 2 = 451) examined the roles of hope and religious coping (positive and negative) in promoting well-being during periods when stringent stay-at-home orders were implemented in Colombia and South Africa to control the spread of SARS-CoV-2. After controlling for relevant sociodemographic characteristics (Studies 1 and 2), subjective health complaints, and sleep quality (Study 2), hope was positively associated with well-being and the relation between hope and well-being was moderated by religious coping. Whilst well-being was highest when levels of hope were high (irrespective of positive or negative religious coping levels), when reported hope was low, well-being tended to be higher when positive religious coping was high (Study 1) and negative religious coping was low (Study 2). Implications of the findings for maintaining well-being during a public health crisis are discussed.

A Gay Male Leadership Advantage? How Agency Affects Evaluations of Gay and Straight Male Leaders

The current research contributes to the ongoing debate of the effects of demographic characteristics on leadership evaluations, focusing on sexual orientation. As attitudes toward sexual minorities have rapidly changed in recent years, a more thorough understanding of the workplace experiences of sexual minority employees has become essential. The current set of studies examines perceptions of gay male leaders as a function of their agency or communality, which are two traits important to effective leadership evaluations. The three experiments considered whether gay male leaders displaying agency led to a gay male leadership advantage, as predicted by expectancy violation theory. In Study 1, participants rated gay male leaders as more agentic and less communal than comparable heterosexual male leaders. Study 2 showed that agentic gay male leaders were evaluated more positively than agentic heterosexual male leaders. No differences emerged for evaluations of communal gay or heterosexual male leaders. Study 3 showed the same pattern of results as Study 2, using a different type of leader (i.e., a political leader). The results of these studies support the existence of a qualified gay male leadership advantage. Implications are discussed in terms of expectancy violation theory and leadership opportunities for sexual minorities.

Differential Effects of High- and Low-Arousal Positive Emotions on Help-Seeking for Depression.

The current set of pre-registered studies tested the effect of savoring a high-arousal (exciting) or low-arousal (calm) positive experience on help-seeking intentions among people with heightened depressive symptomatology. Across all three studies, participants with heightened depressive symptomatology who had not yet sought help were randomly assigned to complete a 6-minute writing task where they reflected on an exciting memory, a calm memory, or what they did today and yesterday. Savoring an exciting memory was associated with significantly greater arousal than savoring a calm memory and the control condition (Study 1; N=218). Both savoring conditions were associated with greater positive emotion than the control condition (Study 2; N=193). In Study 3 (N=1,238), savoring an exciting memory, when compared to the control condition, increased help-seeking intentions, whereas savoring a calm memory did not. The current studies support the use of high-arousal, rather than low-arousal, positive emotions to increase help-seeking intentions among people with depression.

Impact of quercetin on pharmacokinetics of quetiapine: insights from in-vivo studies in wistar rats

Quercetin (QCN) is commonly used in high doses as a dietary supplement for weight loss. Psychotic patients are at greater risk of developing obesity than the general population. The present study was designed to understand the impact of QCN on the exposure of quetiapine (QTE), an anti-psychotic drug with narrow therapeutic index and brain penetrating capability. The content of QTE in rat plasma was analyzed through liquid chromatography–tandem mass spectrometry. The results showed a significant (p < 0.05) increase in exposure of QTE (peroral dosed) in the animals pre-treated with QCN as compared to the control group. All the animals pre-treated with QCN, succumbed to death within 3–5 min of intravenous dosing of QTE (1 mg/kg). The studies in rat liver S9 fraction indicated that QCN could increase the metabolic stability of QTE by inhibiting the activity of CYP enzymes. The brain to plasma ratio of QTE increased upon QCN pre-treatment (2.6 vs 7.7), which could be attributed to P-glycoprotein inhibition at the blood–brain barrier by QCN. The current set of studies indicated that serious herb–drug interaction between QCN and QTE might occur when they are co-administered. Caution is advised for concomitant use of QCN rich dietary supplements with QTE.

Leader‐Member Exchange (LMX) and innovation: A test of competing hypotheses

In this paper, we address the relation between Leader‐Member Exchange (LMX; the quality of the relationship between leader and subordinate), employee creativity (the generation of novel and useful ideas), and employee innovation (the promotion and implementation of these ideas). In the current set of studies, we test the competing hypotheses that LMX will either have a direct effect on employee innovation, or an indirect effect through employee creativity. In a field study of leader–subordinate dyads (N = 118), we found that LMX had no direct effect on employee innovation, and that employee creativity fully mediated the relationship between LMX and innovation. In a follow‐up two‐wave field study of employees (N = 398), we found that the LMX dimension professional respect predicted innovation through creativity, while the other dimensions did not. The results of this work indicate that research on LMX and innovation requires a multidimensional perspective, and that it may be valuable to differentiate between creativity and innovation.