Current State Of Research Research Articles

Review on research and development of planetary penetrator

AbstractA planetary penetrator is a kind of machine that can use its special structure to independently penetrate an exoplanet and sample it for storage. It is a hot research topic in the world and has important development potential in the field of deep space exploration. Based on the analysis of relevant literature, this paper classifies and compares various representative planetary penetrator projectiles around the current research status. The development progress and key technologies of the planetary penetrator are analyzed, the current technical challenges are summarized, and the development trend of the planetary penetrator has prospected. The planetary probe has a broad application prospect, and its development will provide technical support for humans to establish extraterrestrial habitat, and play an important role in the field of deep space exploration. Currently, planetary penetrator research is still in its infancy, and the field is full of possibilities that need to be explored and improved.

Mapping trends and hotspots regarding the use of telenursing for elderly individuals with chronic diseases: A bibliometric analysis.

Telenursing is receiving extensive attention from scholars and medical staff. However, there are few studies on the knowledge structure of telenursing for elderly individuals with chronic diseases. This study aims to demonstrate current research status and development trend of telenursing for elderly individuals with chronic diseases through a visual analysis of CiteSpace, so as to provide a more comprehensive perspective for future researches. Literature about telenursing for elderly patients with chronic diseases from 2002 to 2022 was retrieved from the Web of Science Core Collection using CiteSpace 6.1.R3. A total of 375 records were obtained. Annual publication and citation frequency gradually increased over the investigated period, reaching a peak in 2022. Journal of Telemedicine and Telecare was the most prolific and the most cited journal. The United States was the most productive country, the University of Melbourne was the most productive institution, and the author CHEN C ranked the highest in the number of publications. The most popular keywords were "care," "telemedicine," "management," "older adult," "chronic disease," "health," and "heart failure," which had a high frequency and centrality. The keywords "telehealth," "randomized controlled trail," "chronic obstructive pulmonary disease," "implementation" and "time" showed the strongest citation burst. The keywords were clustered to form 10 labels. The article published in 2010 by Chaudhry SI was cited the most. The top 3 cited journals were all special journal of telemedicine. This study revealed current research status and development trend of telenursing for elderly individuals with chronic diseases. The bibliometric analysis of telenursing expands the knowledge field of telemedicine and provides new insights into the management of elderly patients with chronic diseases.

장애인 자가운전에 관한 체계적 문헌 고찰: 국내문헌을 중심으로

Objective: This study systematically analyzed and reviewed literature on self-driving for the disabled published in Korea over the past 10 years. Methods: We searched literature published between January 2014 and December 2023 in the Library of Congress, RISS, KISS, DBpia, and Google Scholar. The search terms “disabled” and “self-driving” were used, and a total of 469 documents were searched. Of these, 28 articles that met the selection criteria were analyzed. Results: Research published domestically on self-driving for the disabled was gradually decreasing. The most common type of published literature was academic journals. The first author who conducted literature research most often belonged to the Department of Occupational Therapy and the Department of Rehabilitation Science and Engineering, and the most common research area was the establishment of systems to promote and support self-driving for the disabled. The majority of research designs were experimental studies, but the overall level of research was confirmed to be low. Conclusion: Analyzing literature on self-driving for the disabled published domestically, we were able to understand the current status of research in our country. This study is significant as basic data that can be used as a reference when an advanced system that can support and guarantee self-driving for the disabled is introduced in Korea in the future.

The Current Research Status of ICU-Acquired Muscle Weakness

ICU-acquired weakness is the most common neuromuscular injury in critically ill patients and an important issue that affects their long-term quality of life. Although ICU-acquired weakness has received increasing attention in recent years, there is still no consensus on its pathophysiological mechanisms, and there are knowledge gaps in identifying high-risk patients and subsequent treatment. This article summarizes the research on ICU-acquired weakness in terms of pathophysiological mechanisms, diagnostic methods, and treatment through a literature review.

Progress and Prospect of Dscam Gene in Drosophila Immunity

The cell adhesion molecule (Dscam) gene in Down syndrome is an extraordinary example of diversity: by combining alternative splicing exons, thousands of subtypes can be generated from just one gene. So far, this diversity of the gene has only been found in insects and crustaceans, and the basic part of neural connections has been well characterized as Drosophila melanogaster. More than a decade ago, evidence from Drosophila melanogaster indicated that the Dscam gene is involved in insect immune defense. However, we are still far from fully understanding the functions of Dscam in parasites and pathogens, as well as its full correlation with the immune system. In this article, we first briefly introduce the immune mechanism of fruit flies and the current research status of Dscam. Finally, the future research prospects of Dscam are summarized and proposed, with the aim of providing a multi perspective perspective to further study the relationship between this gene and immune defense in detail.

Current Research Status of Primary Closure after Laparoscopic Biliary Exploration

Choledocholithiasis is a biliary system disorder that plagues people's health. With the use and development of minimally invasive techniques, laparoscopy, duodenoscopy, and choledochoscopy, the treatment of choledocholithiasis has become more demanding, and in recent years, several studies have shown that primary closure after laparoscopic biliary exploration demonstrates a therapeutic efficacy not inferior to the placement of a T-tube for drainage in the postoperative period. Summarizing the studies published in the last 5 years on primary closure after laparoscopic biliary exploration, the results show that in appropriate cases, primary closure after laparoscopic biliary exploration is safe and effective, and compared with T-tube drainage, it can reduce the length of hospital stay, the hospitalization cost, and improve the quality of life of patients.

Research status and hotspots on the mechanisms of liver X receptor in cancer progression: A bibliometric analysis.

The mechanism of liver X receptor in cancer has been gradually revealed in recent years. This study is committed to analyzing the current research status of the mechanism of liver × receptor in cancer progression by using bibliometric methods and to explore the development trend of liver × receptor related research in the future, in order to provide some reference for further exploration in this field. The Web of Science core collection database was used to carry out the original data retrieval. Excel software was used for data statistics. Vosviewer and CiteSpace software were used to analyze the publication situation, cooperation network, reference co-citation, keyword and term co-occurrence, term bursts, and cluster analysis, and draw visual maps. A total of 631 publications meeting the research criteria were included by December 2022, with an average of 32.5 citations per paper. The main research fields were molecular biology, oncology and cell biology, and the papers were mainly published in journals about molecular, biology and immunology. Cell is the journal with the highest citation. The United States is the most influential country, the University of California, Los Angeles is the main research institution, and Gustafsson, Jan-ake is the author with the highest output. In reference co-citation clustering, cluster#2 "cancer development" is the main cluster, and the period from 2014 to 2018 is an important stage of relevant theoretical progress. "Tumor microenvironment" with high burst and novelty became the most noteworthy term in term burst. Using bibliometric methods to reveal the current status of LXR and cancer mechanisms, and making predictions of possible future hotspots based on the analysis of the current situation, the translation of LXR anti-cancer research to clinical applications, the impact on the tumor microenvironment as a whole and more immune pathways, and the formation of a systematic cognition of the effects of more cancer cell lines and oncogenic signaling crosstalk, which is a possible direction for future research.

Visualization and Analysis of Mapping Knowledge Domains for Coal Functional Groups

ABSTRACT In this paper, a systematic review of the research on functional groups in coal is presented. In recent years, the research on functional groups in coal has been extended from the macroscopic level to the microscopic layer, and a large number of studies have shown that functional groups have significant effects on various properties of coal, such as gas adsorption and spontaneous combustion. To understand the current status and future trends of research on functional groups in coal, this study analyzed 3956 papers on this topic published in the Web of Science (WOS) core database from 2000 to 2022. The spatial and temporal distribution characteristics of publications, authors, countries, institutions, and major journals were visualized using VOSviewer and CiteSpace. Keyword co-occurrence and burst analysis are used to reveal the research status and hotspots in this field. The results show that the development of research on functional groups in coal goes through three stages: the fluctuating development period, the steady development period, and the results explosion period; China, USA, Australia, Japan, and India are the most active countries in the field of coal functional groups research, and China has a greater advantage in the number of publications and influence. A core group of institutions, mainly research universities, has been formed in this field, and Fuel, Energy and Fuels and Fuel Processing Technology are the main source journals for published results on coal functional groups. At present, the framework of basic theories and research methods is complete, and the study of functional groups for gas adsorption, the analysis of the evolution of functional groups in the process of coal thermodynamic behavior, and the characteristics of functional group categories and distribution in coal are the main knowledge framework basis for the study of functional groups in coal. The research on coal functional groups has been extended to the molecular level, and in the future, quantum chemistry, molecular simulation, and fine characterization research of functional groups will become the frontier of research in the field of coal functional groups.

Visual Analysis of Research Hotspots on Near Miss in the Nursing Field

Objective To analyze the current research status, hot spots and dynamic frontiers of literature related to near misses in nursing using visual knowledge mapping, in order to provide a reference for the future development of near misses in nursing. Methods The literature related to near misses in nursing was searched in the Web of Science core collection from its establishment to August 2022, and visualized and analyzed in terms of the number of articles, journals and keywords. Results A total of 289 papers were included, and the annual publication volume showed a trend of year-on-year growth, with the United States taking the first place in terms of publication volume and the initial formation of a core author team, and the hotspots of proximity research in the nursing field were mainly focused on patient safety, safety management, and identification reporting. Conclusion The research related to proximity errors in nursing started late, and the current research on proximity errors is not comprehensive enough. Since the occurrence of proximity errors can have adverse effects on patients, nursing staff and medical institutions, it is suggested that nursing managers should increase the importance of this issue, pay attention to the frontier development, and conduct in-depth related research.

A Review of Chloride Corrosion Resistance of Ultra-High-Performance Concret

Extending the service life of reinforced concrete structures can effectively reduce the economic, environmental, resource and energy costs throughout their life cycle. However, a large number of reinforced concrete structures often suffer from corrosion of reinforcing bars due to chloride ion erosion in various environments, which leads to deterioration of performance, the loss of functionality and even safety accidents. As a barrier between reinforcing steel and the external environment, protective layer concrete can effectively prevent chloride ions from contacting the surface of reinforcing steel, thus delaying the corrosion of reinforcing steel and improving the durability of reinforced concrete structures. Ultra-high-performance concrete has a dense microstructure due to its low water-to-cement ratio and elimination of coarse aggregates, which can greatly impede the transport of chloride ions within it, and thus it is expected to significantly improve the service life of reinforced concrete infrastructure. Based on this, this paper firstly summarizes the basic mechanism of chloride ion transport inside cementitious materials, including the movement mode and physicochemical binding mechanism of chloride ions inside the cementitious, and analyzes the current research status and improvement methods of the chloride ion penetration and chloride ion binding capacity of ultra-high-performance concrete.

A Review of Studies on the English Translation of Shanghanlun

This paper mainly uses the methods of big data and statistical analysis to explore the current research status of the English translation of Shanghanlun, finding that there are a total of 69 pieces of literatures related to the book in China in the past decade, including 41 researches on the translation strategies, 21 on the comparison of the translations, 3 on the translation history, 2 corpus-based researches on the translations and 2 researches on the dissemination of the translations. The first two types of researches are more popular, and the research contents are mostly have something in common. In addition, the translation objects that have been mainly studied are the translation of Luo Xiwen, the translation of Nigel Wiseman and the translation of Li Zhaoguo, only accounting for a small number of existing translations. By contrast, the three aspects of research on the translation history, corpus-based research and research on the dissemination of the translations need to be further studied.

Safety Risk Assessment Analysis of Bridge Construction Using Backpropagation Neural Network

The evaluation of construction safety risks has become a crucial task with the increasing development of bridge construction. This paper aims to provide an overview of the application of backpropagation neural networks in assessing safety risks during bridge construction. It introduces the situation, principles, methods, and advantages, as well as the current status and future development directions of backpropagation-related research.

STARA Awareness: Work Stressors in the Age of Industry 4.0

 STARA awareness characterizes employees' perception of the extent to which the use of emerging information technologies such as STARA (Smart Technology, Artificial Intelligence, Robotics, and Algorithms) in the workplace affects their personal career development in the context of the Fourth Industrial Revolution. On the basis of combing domestic and international literature, scholars systematically organize the concept of STARA awareness, measurement scales, and elaborate the current research status of antecedent and outcome studies as well as mediating and moderating mechanisms of STARA awareness. Finally, we further prospect the future research direction of STARA awareness. Future research should further explore the specific factors that influence the emergence of STARA awareness and expand the mediating mechanisms and outcome effects of STARA awareness.

Ischemic stroke pathophysiology: A bibliometric and visualization analysis from 1990 to 2022

BackgroundPathophysiology plays a significant role in the scientific study of ischemic stroke, and has attracted increasing interest from researchers in the field. However, a comprehensive bibliometric analysis is lacking in this field. The purpose of this study is to identify the current research status and hotspots of ischemic stroke pathophysiology from a bibliometric perspective. MethodsThe Web of Science Core Collection database was searched for articles published from 1990 to 2022. CiteSpace, VOSviewer, and R package “bibliometrix” software were used to analyze countries/regions, institutions, journals, authors, papers, and keywords to predict the latest trends in ischemic stroke pathophysiology research. ResultsThis analysis collected 7578 records of ischemic stroke pathophysiology. China and America emerged as the leading countries in this field, with Harvard University being the most active institution. Among journals and authors in this field, journal Stroke and author Gregory YH Lip published the most papers, while Nature Medicine was the journal with the highest citation per article. Keywords and co-citation clusters were closely related to “central nervous system”, “mechanisms”, “biochemistry & molecular biology” and “radiology, nuclear medicine & medical imaging”, while other related fields, such as peripheral organs damage induced by the central nervous system and rehabilitation after ischemic stroke, require further research efforts. ConclusionThis is the first bibliometric study that comprehensively mapped out the knowledge structure and development trends of ischemic stroke pathophysiology in recent 32 years, which may provide a reference for scholars to explore ischemic stroke pathophysiology.

Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies.

As the world population ages, there will be an increasing need for effective therapies for aging-associated neurodegenerative disorders, which remain untreatable. Dementia due to Alzheimer's disease (AD) is one of the leading neurological diseases in the aging population. Current therapeutic approaches to treat this disorder are solely symptomatic, making the need for new molecular entities acting on the causes of the disease extremely urgent. One of the potential solutions is to use compounds that are already in the market. The structures have known pharmacokinetics, pharmacodynamics, toxicity profiles, and patient data available in several countries. Several drugs have been used successfully to treat diseases different from their original purposes, such as autoimmunity and peripheral inflammation. Herein, we divulge the repurposing of drugs in the area of neurodegenerative diseases, focusing on the therapeutic potential of antineoplastics to treat dementia due to AD and dementia. We briefly touch upon the shared pathological mechanism between AD and cancer and drug repurposing strategies, with a focus on artificial intelligence. Next, we bring out the current status of research on the development of drugs, provide supporting evidence from retrospective, clinical, and preclinical studies on antineoplastic use, and bring in new areas, such as repurposing drugs for the prion-like spreading of pathologies in treating AD.

Review on high-value utilization of phosphogypsum: Utilization of calcium and oxygen resources present in phosphogypusm

The world's annual production of phosphogypsum (PG) is up to 200 million tons at present. It was found that 15 % of PG produced worldwide is recycled. Therefore, it is imperative to seek a new pathway to recycle PG. This work provides an overview of the state-of-the-art scheme for high-value utilization of PG. Compared with previously published works, this review focuses on the utilization of oxygen (O) and calcium (Ca) resources. The state-of-the-art technology of utilizing O in PG consists of lignite’s chemical looping gasification (CLG) with PG-based oxygen carrier. The state-of-the-art technology for utilizing Ca in PG is the low-temperature decomposition of PG for producing CaO and CaCO3 from the reductive decomposition of PG. The process and the reaction mechanism of state-of-the-art technology for application of O and Ca in PG are summarized. Based on current research status, it is suggested to apply two or more solid wastes in cement, bricks and other aspects of large-scale. When utilizing PG, the migration transformation of impurities in PG and their reaction mechanisms at the molecular level deserve to be focused on. The key to solving the problems caused by PG large consumption, high value-added utilization and the introduction of policies providing incentives to this end. This research provides guidance for new engineering techniques for PG to achieve high-value and efficient use of resources in the large-scale utilisation of PG.

Engineered exosomes in emerging cell-free therapy.

The discovery and use of exosomes ushered in a new era of cell-free therapy. Exosomes are a subgroup of extracellular vesicles that show great potential in disease treatment. Engineered exosomes. with their improved functions have attracted intense interests of their application in translational medicine research. However, the technology of engineering exosomes still faces many challenges which have been the great limitation for their clinical application. This review summarizes the current status of research on engineered exosomes and the difficulties encountered in recent years, with a view to providing new approaches and ideas for future exosome modification and new drug development.

The concept of "state fishes of India": Current status, knowledge gaps, and strategic plans for conservation and sustainable utilization.

The concept of "state fishes of India" highlights the importance and significance of the prioritized fish species distributed across various states within the country. This review article systematically documents the current status of state fishes from various perspectives, identifies the prevailing knowledge gaps, and also highlights the issues and strategic plans essential for the conservation and sustainable utilization of these valuable genetic resources. A total of 8357 publications were checked for the consolidated information on state fish species, and the appropriate items were selected under eight categories: biology, physiology and nutrition, aquaculture, habitat and environmental parameters, genetics and biotechnology, harvest and postharvest, fish health management, and others. The synthesized information was used to present the current status of research and development on state fish species. The knowledge gaps that are to be addressed are also depicted under the perspectives of fisheries management and conservation aquaculture. Based on the findings, strategic plans for the targeted conservation programmes are proposed and discussed under various in situ and ex situ conservation measures. Further, the departmental processes involved in the declaration, the importance of stakeholder involvement, namely, local communities and policymakers, in fostering effective conservation measures, and planning for utilization of these valuable fish genetic resources are also indicated.

Shared Decision-Making in Cardiovascular Risk Factor Management

The effect of shared decision-making (SDM) and the extent of its use in interventions to improve cardiovascular risk remain unclear. To assess the extent to which SDM is used in interventions aimed to enhance the management of cardiovascular risk factors and to explore the association of SDM with decisional outcomes, cardiovascular risk factors, and health behaviors. For this systematic review and meta-analysis, a literature search was conducted in the Medline, CINAHL, Embase, Cochrane, Web of Science, Scopus, and ClinicalTrials.gov databases for articles published from inception to June 24, 2022, without language restrictions. Randomized clinical trials (RCTs) comparing SDM-based interventions with standard of care for cardiovascular risk factor management were included. The systematic search resulted in 9365 references. Duplicates were removed, and 2 independent reviewers screened the trials (title, abstract, and full text) and extracted data. Data were pooled using a random-effects model. The review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guideline. Decisional outcomes, cardiovascular risk factor outcomes, and health behavioral outcomes. This review included 57 RCTs with 88 578 patients and 1341 clinicians. A total of 59 articles were included, as 2 RCTs were reported twice. Nearly half of the studies (29 [49.2%]) tested interventions that targeted both patients and clinicians, and an equal number (29 [49.2%]) exclusively focused on patients. More than half (32 [54.2%]) focused on diabetes management, and one-quarter focused on multiple cardiovascular risk factors (14 [23.7%]). Most studies (35 [59.3%]) assessed cardiovascular risk factors and health behaviors as well as decisional outcomes. The quality of studies reviewed was low to fair. The SDM intervention was associated with a decrease of 4.21 points (95% CI, -8.21 to -0.21) in Decisional Conflict Scale scores (9 trials; I2 = 85.6%) and a decrease of 0.20% (95% CI, -0.39% to -0.01%) in hemoglobin A1c (HbA1c) levels (18 trials; I2 = 84.2%). In this systematic review and meta-analysis of the current state of research on SDM interventions for cardiovascular risk management, there was a slight reduction in decisional conflict and an improvement in HbA1c levels with substantial heterogeneity. High-quality studies are needed to inform the use of SDM to improve cardiovascular risk management.

Review and Research on Medical Waste Recycling Network

The mass production of medical wastes has tested the safety of urban public health, and the recovery and disposal of medical wastes is imminent. Under various environmental backgrounds, such as the sudden increase in the number of medical wastes, the late start of the medical waste recycling industry in China, the low disposal rate, and the improper treatment of medical wastes affecting the environment and personal safety, medical wastes should be managed in a timely and standardized manner, and effective strategies should be put forward to minimize the environmental pollution caused by medical wastes. Therefore, in recent years, this paper studies the optimization of medical waste recycling network and summarizes the current research status of medical waste recycling network in academic circles.