Current Concepts Research Articles

Implementation of the Independent Curriculum in Building the Character Profile of Pancasila Students Based on Tri Hita Karana in Elementary Schools

One of the most important achievements of education is the development of Pancasila-based character and behavior that are able to make the name of the region and nation proud. Currently, education must be adapted to the current curriculum concept, namely the Merdeka curriculum, in order to produce students who are creative, imaginative, and characterful. Because Tri Hita Karana has a consistent goal of achieving happiness or harmony in life, it is very consistent with building a character profile of Pancasila students, which is one of the objectives of implementing the Independent Curriculum. Learning today is very close to technological changes; therefore, it is important to balance students in managing life harmony to build student character with the idea of Tri Hita Karana.

Implementation of the Independent Curriculum in Building the Character Profile of Pancasila Students Based on Tri Hita Karana in Elementary Schools

One of the most important achievements of education is the development of Pancasila-based character and behavior that are able to make the name of the region and nation proud. Currently, education must be adapted to the current curriculum concept, namely the Merdeka curriculum, in order to produce students who are creative, imaginative, and characterful. Because Tri Hita Karana has a consistent goal of achieving happiness or harmony in life, it is very consistent with building a character profile of Pancasila students, which is one of the objectives of implementing the Independent Curriculum. Learning today is very close to technological changes; therefore, it is important to balance students in managing life harmony to build student character with the idea of Tri Hita Karana.

Isolated volar dislocation of the distal radioulnar joint: Current concepts review and case report

Isolated volar distal radioulnar joint (DRUJ) dislocation is a rare condition with only a few cases reported in the literature. Its diagnosis is often overlooked in the acute phase, and there is no consensus in its management. We present the case of a 20-year-old male patient with an isolated volar radioulnar dislocation, together with a review of the literature. The aim is to present and summarize the acute management of this condition and propose a therapeutic algorithm.

Modeling quantum optical phenomena using transition currents

Spontaneous light emission is central to a vast range of physical systems and is a founding pillar for the theory of light–matter interactions. In the presence of complex photonic media, the description of spontaneous light emission usually requires advanced theoretical quantum optics tools such as macroscopic quantum electrodynamics, involving quantized electromagnetic fields. Although rigorous and comprehensive, the complexity of such models can obscure the intuitive understanding of many quantum-optical phenomena. Here, we review a method for calculating spontaneous emission and other quantum-optical processes without making explicit use of quantized electromagnetic fields. Instead, we introduce the concept of transition currents, comprising charges in matter that undergo transitions between initial and final quantum states. We show how predictions that usually demand advanced methods in quantum electrodynamics or quantum optics can be reproduced by feeding these transition currents as sources to the classical Maxwell equations. One then obtains the relevant quantum observables from the resulting classical field amplitudes, without washing out quantum optical effects. We show that this procedure allows for a straightforward description of quantum phenomena, even when going beyond the dipole approximation and single emitters. As illustrative examples, we calculate emission patterns and Purcell-enhanced emission rates in both bound-electron and free-electron systems. For the latter, we derive cathodoluminescence emission and energy-loss probabilities of free electrons interacting with nanostructured samples. In addition, we calculate quantum-beat phenomena in bound-electron systems and wave function-dependent optical coherence in free-electron systems. Remarkably, the transition-current formalism captures more complex phenomena, such as many-body interference effects and super-radiance of both bound- and free-electron systems, second-order processes such as two-photon emission, and quantum recoil corrections to free-electron radiation. We review a variety of light–matter interactions in fields ranging from electron microscopy to nanophotonics and quantum optics, for which the transition-current theoretical formalism facilitates practical simulations and a deeper understanding of novel applications.

Modeling quantum optical phenomena using transition currents

Spontaneous light emission is central to a vast range of physical systems and is a founding pillar for the theory of light–matter interactions. In the presence of complex photonic media, the description of spontaneous light emission usually requires advanced theoretical quantum optics tools such as macroscopic quantum electrodynamics, involving quantized electromagnetic fields. Although rigorous and comprehensive, the complexity of such models can obscure the intuitive understanding of many quantum-optical phenomena. Here, we review a method for calculating spontaneous emission and other quantum-optical processes without making explicit use of quantized electromagnetic fields. Instead, we introduce the concept of transition currents, comprising charges in matter that undergo transitions between initial and final quantum states. We show how predictions that usually demand advanced methods in quantum electrodynamics or quantum optics can be reproduced by feeding these transition currents as sources to the classical Maxwell equations. One then obtains the relevant quantum observables from the resulting classical field amplitudes, without washing out quantum optical effects. We show that this procedure allows for a straightforward description of quantum phenomena, even when going beyond the dipole approximation and single emitters. As illustrative examples, we calculate emission patterns and Purcell-enhanced emission rates in both bound-electron and free-electron systems. For the latter, we derive cathodoluminescence emission and energy-loss probabilities of free electrons interacting with nanostructured samples. In addition, we calculate quantum-beat phenomena in bound-electron systems and wave function-dependent optical coherence in free-electron systems. Remarkably, the transition-current formalism captures more complex phenomena, such as many-body interference effects and super-radiance of both bound- and free-electron systems, second-order processes such as two-photon emission, and quantum recoil corrections to free-electron radiation. We review a variety of light–matter interactions in fields ranging from electron microscopy to nanophotonics and quantum optics, for which the transition-current theoretical formalism facilitates practical simulations and a deeper understanding of novel applications.

An Ethics of Care Perspective on Care to Battlefield Casualties

ABSTRACT Soldiers hold special ethical obligations to prioritise care for those closest to them when dealing with combat casualties. This obligation draws on the unique, personal relationships already established, which soldiers have with their comrades. These relationships arguably overrule the need for impartiality barring only a significant difference in the severity of injuries. The bonds of fraternity deserve moral recognition that is not reflected in current conceptions of battlefield medical care. However, an ethics of care (or care ethics) approach does not reject care for enemies but suggests that extension to them occurs when there is no significant difference in severity to comrades first. It also calls on a different form of care called ethical caring, which as opposed to natural caring requires introspection on behalf of the caregiver. Ethics of care distinguishes treatment of the enemy from emotionally detached positions. Emotional detachment rejects the call to care and denies the development of a relationship, which is a foundational principle of care ethics.

An Ethics of Care Perspective on Care to Battlefield Casualties

ABSTRACT Soldiers hold special ethical obligations to prioritise care for those closest to them when dealing with combat casualties. This obligation draws on the unique, personal relationships already established, which soldiers have with their comrades. These relationships arguably overrule the need for impartiality barring only a significant difference in the severity of injuries. The bonds of fraternity deserve moral recognition that is not reflected in current conceptions of battlefield medical care. However, an ethics of care (or care ethics) approach does not reject care for enemies but suggests that extension to them occurs when there is no significant difference in severity to comrades first. It also calls on a different form of care called ethical caring, which as opposed to natural caring requires introspection on behalf of the caregiver. Ethics of care distinguishes treatment of the enemy from emotionally detached positions. Emotional detachment rejects the call to care and denies the development of a relationship, which is a foundational principle of care ethics.

Treating the injured: a privilege conferred by both patient and wider society.

Two discrete legal factors enable the surgeon to treat an injured patient the fully informed, autonomous consent of the adult patient with capacity via civil law; and the medical exception to the criminal law. This article discusses current concepts in consent in trauma; and also considers the perhaps less well known medical exception to the Offences against the Person Act 1861, which exempts surgeons from criminal liability as long as they provide 'proper medical treatment'.

The subcutaneous adipose transcriptome identifies a molecular signature of insulin resistance shared with visceral adipose.

The objective of this study was to identify the transcriptional landscape of insulin resistance (IR) in subcutaneous adipose tissue (SAT) in humans across the spectrum of obesity. We used SAT RNA sequencing in 220 individuals with metabolic phenotyping. We identified a 35-gene signature with high predictive accuracy for homeostatic model of IR that was expressed across a variety of non-immune cell populations. We observed primarily "protective" IR associations for adipocyte transcripts and "deleterious" associations for macrophage transcripts, as well as a high concordance between SAT and visceral adipose tissue (VAT). Multiple SAT genes exhibited dynamic expression 5 years after weight loss surgery and with insulin stimulation. Using available expression quantitative trait loci in SAT and/or VAT, we demonstrated similar genetic effect sizes of SAT and VAT on type 2 diabetes and BMI. SAT is conventionally viewed as a metabolic buffer for lipid deposition during positive energy balance, whereas VAT is viewed as a dominant contributor to and prime mediator of IR and cardiometabolic disease risk. Our results implicate a dynamic transcriptional architecture of IR that resides in both immune and non-immune populations in SAT and is shared with VAT, nuancing the current VAT-centric concept of IR in humans.

The Perizonium Ultrastructure, Divided Apical Pore Fields, Various Pore Occlusions and Visible Intermissio of Cymbella (Bacillariophyceae) with Descriptions of Four New Species.

The initial valves of two Cymbella species are observed under a scanning electron microscope, and the perizonium ultrastructure of Cymbella is revealed for the first time. The perizonium is composed of alternate nodes and internodes and lacks transverse perizonium bands. Four new species, Cymbella apiculatophora sp. nov., C. hunanensis sp. nov., C. juglandis sp. nov. and C. menyuanensis sp. nov., are described using light and scanning electron microscopy based on epilithon samples collected from rivers in Hunan and Qinghai Provinces, China. Cymbella menyuanensis is a typical Cymbella species that closely resembles species in the group around C. cymbiformis Agardh, the type species of the genus. Cymbella apiculatophora is similar to C. sinensis Metzeltin & Krammer, while Cymbella hunanensis is closer to the C. hustedtii Krasske group. The last species, C. juglandis, has a cymbelloid valve outline, an obscured intermissio, internal occlusions of the areolae, dorsally deflected distal raphe fissures and a divided apical pore field at each apex, and it does not appear to belong to any group. In addition, new observations on C. cf. excisiformis Krammer and C. hustedtii are reported. The current concept of the genus Cymbella does not represent a monophyletic group as shown by molecular phylogenetic analyses. However, these analyses are still at the preliminary stage and are not yet sufficient to support a complete revision of the genus. Thus, although extremely diverse ultrastructural features are observed in the six Cymbella species investigated in this paper, we prefer to keep them within Cymbella at this moment for the sake of nomenclatural stability.

Advances in Family Dignity Interventions in Hospice Care

The current concept, background, basic theory, method, and actual application effect of the family dignity intervention proposed are analyzed. The application of family dignity intervention in hospice care in China is studied in the hope that it can effectively promote effective application in the clinic and provide a reference for the clinic.

Advances in Family Dignity Interventions in Hospice Care

The current concept, background, basic theory, method, and actual application effect of the family dignity intervention proposed are analyzed. The application of family dignity intervention in hospice care in China is studied in the hope that it can effectively promote effective application in the clinic and provide a reference for the clinic.

Premature ovarian insufficiency: knowledge, attitudes, and quality of care offered by gynecologists.

Premature ovarian insufficiency (POI) affects up to 3% of the global female population, influencing metabolic, cardiovascular, and reproductive health. Medical expertise in diagnosis, effects, and treatment strategies, particularly for gynecologists, is crucial for ensuring improved healthcare for women. The objective of this study is to assess the state of medical knowledge regarding the diagnosis, treatment, and follow-up of POI among Brazilian gynecologists. A cross-sectional study was conducted using online questionnaires administered to 16,000 members of the Brazilian Federation of Gynecology and Obstetrics. In total, 460 questionnaires were received from gynecologists who had an average age of 44.49 ± 12.57 years and 19.37 ± 12.95 years of professional experience. Fifty-three percent of gynecologists diagnosed POI correctly, and 49% requested karyotype analysis, while fewer than 10% identified all POI etiologies. Over 90% of gynecologists understood the long-term consequences of POI for bone and cardiovascular health. Despite being a consequence of hypoestrogenism, hormone therapy was recommended only by 20% of doctors, with no more than 50% of them prescribing appropriate doses for young women. Regarding self-perception, 60% of gynecologists declared deficient knowledge regarding how to offer care and guidance to women, with hormone therapy being reported as the most important reason (47%). Current concepts and guidelines for POI are not adequately understood or applied in Brazilian clinical practice, leading to suboptimal care.

Towards nutrition with precision: unlocking biomarkers as dietary assessment tools.

Precision nutrition requires precise tools to monitor dietary habits. Yet current dietary assessment instruments are subjective, limiting our understanding of the causal relationships between diet and health. Biomarkers of food intake (BFIs) hold promise to increase the objectivity and accuracy of dietary assessment, enabling adjustment for compliance and misreporting. Here, we update current concepts and provide a comprehensive overview of BFIs measured in urine and blood. We rank BFIs based on a four-level utility scale to guide selection and identify combinations of BFIs that specifically reflect complex food intakes, making them applicable as dietary instruments. We discuss the main challenges in biomarker development and illustrate key solutions for the application of BFIs in human studies, highlighting different strategies for selecting and combining BFIs to support specific study designs. Finally, we present a roadmap for BFI development and implementation to leverage current knowledge and enable precision in nutrition research.

Current Concepts in the Epigenetic Regulation of Cardiac Fibrosis

Current Concepts in the Epigenetic Regulation of Cardiac Fibrosis

Effect of recycled polypropylene on migration of six processing aids in polypropylene film to milk

Mechanically recycled plastics used in food packaging are consistent with the current circular economy concept. In this study, the effects of recycled polypropylene (rPP) content on film properties and the migration of processing aids in the film to food simulant and milk were studied by self-made rPP films. The results showed that the rPP and processing aids increased the transparency of the films. However, the presence of tiny particles in the rPP film reduced its elongation at break. Furthermore, rPP and processing aids decreased the thermal stability of the film. At 70 °C for 2 h, the total migration order of the processing aids to food simulant and milk was 50 % ethanol (55.78–64.17 mg/kg) > whole milk (10.32–10.66 mg/kg) > low-fat milk (6.39–7.04 mg/kg) > skim milk (4.88–5.47 mg/kg). The migration of processing aids into milk in films containing 50 % and 100 % rPP was similar to that of virgin polypropylene (vPP) films, which indicates that rPP does not promote processing aid migration. Moreover the overall migration order of processing aids to 2 % (w/v) food ingredient aqueous solution was lecithin (3.05 mg/kg) > glyceryl trilaurate (2.68 mg/kg) > cholesterol (1.33 mg/kg) > NaCl (0.33 mg/kg) > casein (0.32 mg/kg) > lactose (0.29 mg/kg) > water (0.16 mg/kg). This confirmed that milk fat was the primary cause of processing aids migration from the film, and the kind of milk fat also had an effect on processing aids migration. Therefore, as long as the basic performance and food safety of packaging are met, a certain proportion of rPP can be added to vPP to achieve sustainable development of packaging.

A multiscale analysis of coralline algae Lithophylloideae (Corallinophycidae, Rhodophyta) shedding new light on understanding cryptic diversity

Cryptic diversity abounds in many biological species, posing challenges to our understanding of biological diversity, conservation and management. Taking the common coralline algae, the subfamily Lithophylloideae as an illustration, this study delved into the implications of cryptic diversity through global-level phylogenetic and geographical analysis based upon Lithophylloideae molecular data worldwide, as well as a multi-locus time-calibrated phylogeny to elucidate their possible evolutionary process. The multiscale analysis revealed the polyphyly in current concept of the genus Lithophyllum. Geographic isolation resulting from the Tethys terminal event (TTE) has led to two distinct distribution regions for this so-called cosmopolitan genus: one regionally distributed along European coasts/Mediterranean that should include the taxonomical Lithophyllum; others widely distributed, particularly among pan-tropic waters, suggesting at least five groups to be rediscovered within the subfamily Lithophylloideae. Meanwhile, the cryptic genus Titanoderma, lacking morphological identification features with Lithophyllum, exhibited differences in distribution and evolutionary patterns consistent with their ecological habits, thus supporting their separation. This study provided useful hints for cryptic diversity, which advocated an integrative thinking to investigating global cryptic diversity and exploring the broad linkages between phylogenetic relationships and evolutionary origin, biogeography, morphological and ecological traits to achieve a more comprehensive understanding of biodiversity.

Single bundle hamstrings autograft preparation techniques for anterior cruciate ligament reconstruction: current concepts.

Anterior cruciate ligament reconstruction (ACLR) is one of the most common orthopedic procedures, and huge variation exists in the surgical technique. Single bundle hamstrings autograft reconstruction is a common method and has good clinical outcomes. A criticism of the hamstrings autograft is a small graft diameter, often less than 8-mm, which has been associated with increased re-rupture rates. Several graft preparation techniques for single bundle hamstrings autograft exist. Perioperative decisions include the number of tendons utilized, number of graft strands, graft configuration, and femoral and tibial fixation methods. Awareness of the minimum tendon and graft length required to produce each graft variation is necessary to avoid common pitfalls. However, intraoperative graft modification is possible to maximize graft diameter, and obtain proper fixation. The objective of this current concepts review is to describe the indications, surgical anatomy, technique, intraoperative tips, clinical outcomes, and complications for single bundle hamstrings autograft preparation techniques in ACLR.

Design and modeling of the case of unmanned aerial vehicle, in the technical facility control system

This article presents the design and modeling of a case with a combat kit for an army unmanned aerial vehicle with an autonomous launch system. The scientific problem solved by the authors in this article is the design and modeling of a new medium-class combat vehicle, according to the current concept of modern design and produc-tion «Industry 4.0», which implies the creation of new dual-use equipment and technologies. The purpose of scien-tific research is the design and modeling of a case with a combat kit for an army unmanned aerial vehicle. The following methods of scientific research were used in the scientific article: theoretical and empirical. The authors associate the prospects of their research with the design and modeling of an innovative control system for a two-case army unmanned aerial vehicle with an autonomous launch system, which has mounts for installation on the chassis of a combat vehicle.

2023 State of the industry report on investment and development of space solar power

Space solar power is an old idea. From its initial suggestion in the 1940s to the first practical concept by Dr. Peter Glaser in 1968, it has been analyzed, studied, and refined many times. Multiple government institutions, including NASA, JAXA, ESA, and CAST have invested significant funds into developing direct space solar power research. In parallel to these direct studies, considerable investment has also flowed into enabling technologies that serve as the cornerstone of current space solar power development concepts, including space solar panels, space hardware manufacturing, low-cost launch, wireless power transfer, robotic assembly, and swarm monitoring/control. In the last few years, space solar power concepts and studies have received increased funding, including non-governmental funding showing a strong positive growth trend. Multiple reports in 2021 and 2022, including from this author, have found that while space solar power has been technically feasible for decades, falling launch and hardware costs have only recently made it economically viable as well. Despite these findings, translation from economic feasibility to economic reality will require additional high-value investment.Sourcing these new funds requires investment context. This technical paper will present a state of the industry report on space solar power, including the total and source distribution of historical investments. It further contextualizes the investments in space solar power with the scale of investment in key technologies and their current technology readiness levels. The methodologies developed for this report and the data sourced are intended to serve as a catalyst, alongside industry feedback, to create a template for ongoing reporting of this growing market sub-sector and ultimately drive the full deployment of this technology.