Current Alcohol Research Articles

"Behavioural and metabolic risk factors of cardiovascular diseases among post-menopausal women: A cross-sectional study in Itahari sub-metropolitan city of Nepal".

Cardiovascular diseases (CVDs) are main cause of mortality and morbidity among women globally. Menopause, aging and different factors in collaboration leads to increased risk for CVDs among postmenopausal women but study on risk factors of CVDs among postmenopausal women is limited in Nepal. Therefore, we aimed to assess prevalence of behavioural and metabolic risk factors of cardiovascular disease among post-menopausal women. Community based cross-sectional study was carried among 390 post-menopausal women of the Itahari sub-metropolitan city. Multistage simple random sampling technique was used to collect data. Modified semi structured questionnaire STEP I, STEP II and STEP III was used as data collection tool. SPSS version 11.5 used for data analysis. Chi-square test and logistic regressions were performed at 95% confidence interval to find predictors of raised blood pressure and overweight/obesity. The mean age of respondents was 63.37 years. The prevalence of current smokers, current alcohol use, less than 5 servings of fruits and vegetables per day, low level of physical activity, overweight/obesity and raised blood pressure was 9.2%, 18.2%, 86.4%, 52.3%, 56.2% and 44.4% respectively. On multivariate analysis strong predictors of overweight obesity were age ≤59 years (AOR: 3.21, CI 1.49-6.89), poor economic status (AOR: 1.764, CI: 1.120-2.779) and low physical activity (AOR: 2.132, CI: 1.350-3.370). Predictors of raised blood pressure were age ≥75 years (AOR: 2.04, CI: 1.01-4.11), unmarried and widow (AOR: 1.815, CI: 1.108-2.971), higher economic status (AOR: 1.752, CI: 1.119-2.740) and smoking (AOR: 4.109, CI: 1.737-9.718). Prevalence of behavioural and metabolic risk factors among postmenopausal women in Itahari sub-metropolitan city were alarmingly high. This calls for an early need of intervention and policies at local, provincial and institutional level to address risk factors of CVDs.

Convergence of Alcohol Consumption and Dietary Quality in US Adults Who Currently Drink Alcohol: An Analysis of Two Core Risk Factors of Liver Disease

Background/Objectives: Alcohol consumption and poor dietary habits are on the rise in the United States, posing significant challenges to public health due to their contribution to chronic diseases such as liver failure. While associations between alcohol consumption patterns and diet quality have been explored, the relationship between specific alcoholic beverage types and diet quality remains underexamined. This study aims to compare diet quality among consumers of different alcoholic beverage types. Methods: We conducted a cross-sectional analysis of 1917 current alcohol drinkers from the National Health and Nutrition Examination Survey (NHANES) who completed a 24 h dietary recall survey. Diet quality was assessed using the Healthy Eating Index (HEI), with higher scores indicating superior diet quality. Multivariable logistic regression models were employed to assess differences in HEI between consumers of various alcoholic beverage types, using wine-only drinkers as the reference group and controlling for demographic, socioeconomic, lifestyle, and metabolic syndrome variables. Results: Beer-only drinkers were more likely to have lower income, higher rates of cigarette smoking, and insufficient physical activity compared to other alcohol consumers. In the fully adjusted multivariable model, beer-only drinkers had an HEI score that was 3.12 points lower than wine-only drinkers. In contrast, liquor/cocktail-only and multiple-type drinkers had similar HEI scores to wine-only drinkers. Conclusions: Beer-only consumption is associated with poorer diet quality among alcohol drinkers. Targeted patient education and public health campaigns may be effective in addressing the combined impact of alcohol consumption and poor diet quality on chronic disease risk.

Prevalence of mental illness and associated factors among the elderly in Ogun East Senatorial District, Nigeria

Abstract Background: Mental health problems are common in the elderly; they often go unnoticed, ignored, untreated, or considered part of normal aging. About a quarter of the Nigerian population have mental health problems, out of which 3.26% are elderly. Aim: This study aimed to determine the prevalence, types, and factors associated with mental illnesses among the elderly. Materials and Methods: This was a community-based cross-sectional survey of the elderly. Four hundred and two elderly people were selected by a multistage sampling technique and were interviewed using semi-structured questionnaires. Data analysis was done using the IBM SPSS Statistics version 22.0. Descriptive statistics were summarized using proportion and presented in frequency tables. Bivariate analyses were done using the Chi-square test and logistic regression analyses. The level of significance was set at a 95% confidence interval with P < 0.05. Results: The prevalence of mental illness among the elderly respondents was 35.8%. Of all the mental illnesses, generalized anxiety disorder ranked the highest (15.4%), followed by current alcohol dependence (14.9%). The factors found to be associated with mental illness in the elderly included monogamous family type (odds ratio [OR] = 0.211, P = 0.034) and monthly income <50,000 Naira (OR = 85.108, P = 0.003). Conclusion: This study revealed that the prevalence of mental illness was high among the community-dwelling elderly respondents of Ogun East Senatorial District. The determinants of mental illness among the elderly were monthly income of <50,000 naira, while monogamous family type was found to be protective of mental illness in the elderly.

Poor sleep hygiene practice and associated factors among adults with epilepsy attending follow up care at Mettu Karl comprehensive specialized hospitals in Illu Ababora Zone and general hospital in Buno Bedele zone, Southwest Ethiopia’

BackgroundGlobally, sleep disorders are an important global public health problem. Poor sleep hygiene is at the core of chronic insomnia and other sleep disorders. Sleep hygiene practices are effective, practical, and affordable, and have no side effects other than other therapies benefiting patients with epilepsy. However, there is no research regarding sleep hygiene practice and its awareness among people with epilepsy in Ethiopia. This study aimed to assess sleep hygiene practice and its factors in patients with epilepsy.MethodsAn institutional-based cross-sectional study was conducted. The study included 424 participants selected through systematic random sampling. An interviewer-administered Sleep Hygiene Index (SHI) questionnaire was used to collect data.The collected data was analyzed using SPSS Version 25.0. Bi-variable and multi-variable analyses were conducted to identify factors related to poor sleep hygiene.ResultsThe frequency of poor sleep hygiene practice among people with epilepsy was 59.5%. Non-adherence to AED (AOR = 1.86, 95% CI: 1.13, 3.23), depression (AOR = 2.10, 95% CI: 1.42, 4.21), poor sleep quality (AOR = 5.7, 95% CI: 3.12, 10.01), anxiety (AOR = 2.71, 95% CI: 1.67, 4.82), and current alcohol drinkers (AOR = 1.74, 95% CI: 1.27, 3.13) were associated with poor sleep hygiene practice.Conclusion and recommendationThe perception of sleep hygiene practice among patients with epilepsy was poor. Non-adherence to AED, depression, poor sleep quality, anxiety, and current use of alcohol were associated with poor sleep hygiene practices. Therefore, regular screening, sleep issue management, and expanded mental health support are crucial. Training programs and awareness strategies to improve sleep hygiene are highly recommended. Professionals should incorporate sleep hygiene in epilepsy care.

Suicidal behaviour, depression and generalized anxiety and associated factors among female and male adolescents in Mozambique in 2022–23

BackgroundThe purpose of the study was to assess the prevalence and associated factors of major depressive disorder (MDD), generalized anxiety disorder (GAD), and past 12-month suicidal behaviour (PSB) among adolescents in Mozambique.MethodsData from 3,109 females (aged 15–19 years) and 1,439 males (aged 15–19 years) that participated in the 2022-23 Mozambique Demographic and health Survey were analysed. MDD was assessed with the PHQ-9 and GAD with the GAD-7.ResultsResults indicate that among girls the prevalence of PSB was 4.3% (attempt 1.0%, plan 1.9% and/or ideation 3.6%) and among boys 2.5% (attempt 0.3%, plan 0.7% and/or ideation 2.4%). Among girls and boys, the prevalence of MDD (≥ 8 scores) was 15.5% and 3.7%, respectively, and the prevalence of GAD (≥ 5 scores) was 25.0% and 10.3%, respectively. In adjusted logistic regression analysis, among girls, GAD was positively and solid fuel use was negatively associated with PSB, while among boys MDD and urban residence were positively associated with PSB. Among female adolescents, currently being pregnant and “big problem to get money for medical treatment” increased the odds of MDD. While among male adolescents, urban residence, having a genital sore or ulcer, has living children, and early sexual debut were positively associated with MDD. Urban residence, current alcohol use, and early sexual debut were positively associated with GAD in male adolescents, while poorer wealth status, being pregnant, and having a “big problem to get money for medical treatment” were positively associated with GAD in female adolescents.ConclusionAbout 3% of participants had PSB, among girls one in five had MDD or GAD and among boys more than 5% had MDD or GAD. Public health interventions can be guided by several associated factors that have been identified.

Couple-Focused Smartphone Intervention to Reduce Problem Drinking: Pilot Randomized Control Trial.

Alcohol use disorder is among the most pervasive substance use disorders in the United States, with a lifetime prevalence of 30%. Recommended treatment options include evidence-based behavioral interventions; smartphone-based interventions confer a number of benefits such as portability, continuous access, and stigma avoidance; and research suggests that interventions involving couples may outperform those for patients only. In this context, a behavioral intervention delivered to couples through smartphones may serve as an effective adjunct to alcohol use disorder treatment. This pilot study aimed to (1) evaluate the feasibility of comparing a patient-only (Addiction version of the Comprehensive Health Enhancement Support System; A-CHESS) versus a couple-focused (Partner version of the Comprehensive Health Enhancement Support System; Partner-CHESS) eHealth app for alcohol misuse delivered by smartphone, (2) assess perceptions about and use of the 2 apps, and (3) examine initial indications of differences in primary clinical outcomes between patient groups using the 2 apps. Broadly, these aims serve to assess the feasibility of the study protocol for a larger randomized controlled trial. A total of 33 romantic couples were randomized to 6 months of A-CHESS app use (active treatment control) or Partner-CHESS app use (experimental). Couples comprised a patient with current alcohol use disorder (25/33, 76% male) and a romantic partner (26/33, 79% female). Patients and partners in both arms completed outcome measure surveys at 0, 2, 4, and 6 months. Primary outcomes were patients' percentage of days with heavy drinking and percentage of days with any drinking, measured by timeline follow back. Secondary outcomes included app use and perceptions, and multiple psychosocial variables. At 6 months, 78% (14/18) of Partner-CHESS patients and 73% (11/15) of A-CHESS patients were still using the intervention. The apps were rated helpful on a 5-point scale (1=not at all helpful, 5=extremely helpful) by 89% (29/33) of both Partner-CHESS patients (mean 3.7, SD 1) and partners (mean 3.6, SD 0.9) and by 87% (13/15) of A-CHESS patients (mean 3.1, SD 0.9). At 6 months, Partner-CHESS patients had a nonsignificantly lower percentage of days with heavy drinking compared with A-CHESS patients (β=-17.4, 95% CI -36.1 to 1.4; P=.07; Hedges g=-0.53), while the percentage of drinking days was relatively equal between patient groups (β=-2.1, 95% CI -24.8 to 20.7; P=.85; Hedges g=-0.12). Initial results support the feasibility of evaluating patient-only and couple-focused, smartphone-based interventions for alcohol misuse. Results suggest that both interventions are perceived as helpful and indicate maintained engagement of most participants for 6 months. A future, fully powered trial is warranted to evaluate the relative effectiveness of both interventions. ClinicalTrials.gov NCT04059549; https://clinicaltrials.gov/ct2/show/NCT04059549.

Risk of Hepatocellular Carcinoma in Asian Patients with Primary Biliary Cholangitis: A Nationwide and Hospital Cohort Study

Background & AimsLarge-scale studies on the association between primary biliary cholangitis (PBC) and hepatocellular carcinoma (HCC) in Asians are scarce. This study aimed to evaluate the incidence of HCC and its risk factors in a nationwide cohort. MethodsThe data of 4,882 patients with PBC and 38,603 matched controls were extracted from the Korean National Health Insurance Service (2007–2020) and analyzed. The incidence of HCC and its risk factors in patients with PBC were assessed and compared with those in the matched controls. The results were validated in a multi-center hospital cohort of 862 patients with PBC, recruited from Asan Medical Center (n=815) and Yeouido St. Mary’s Hospital (n=47) in Korea. ResultsIn total,105 patients with PBC developed HCC over the median follow-up period of 5.42 years, yielding an incidence rate of 3.7/1,000 person-years (PYs), which was significantly higher than that in the controls (0.5/1,000 PYs; adjusted hazard ratio: 9.07; 95% confidence interval [CI]: 6.71–12.27). PBC, older age, male sex, diabetes, and smoking were identified as significant risk factors for HCC. Twenty-three of the 862 patients with PBC developed HCC in the multi-center hospital cohort, yielding an incidence of 4.0/1,000 PYs (95% CI: 2.4–5.7). Older age (subdistribution hazard ratio [SHR]: 1.05, 95% CI: 1.00–1.10), male sex (SHR: 3.00, 95% CI: 1.11–8.13), current alcohol consumption (SHR: 3.70, 95% CI: 1.08–12.59), and cirrhosis (SHR: 5.17, 95% CI: 2.07–12.93) were identified as risk factors in the hospital cohort. ConclusionPatients with PBC were at a significantly higher risk of developing HCC. Older age and male sex were consistent risk factors in both cohorts. Impact and implicationsNotable heterogeneity has been observed among different studies in terms of the incidence of hepatocellular carcinoma (HCC) in patients with primary biliary cholangitis (PBC). Large-scale studies on the association between PBC and HCC in Asians are scarce. In our nationwide cohort study, patients with PBC exhibited a significantly heightened risk of developing HCC and mortality than the age- and sex-matched controls. Individuals with PBC had a 9.1-fold higher risk of developing HCC than their matched counterparts, with an incidence rate of 3.7 per 1,000 person-years. Older age, male sex, smoking, and diabetes were identified as prominent risk factors for HCC in patients with PBC in the nationwide cohort. Older age, male sex, and alcohol consumption were identified as the factors significantly contributing to the elevated risk of HCC in patients with PBC in validation multicenter hospital cohort.

Lifestyle related health risk factors regarding non-communicable diseases among adults in Morang District

Introduction: Non-communicable diseases are the leading causes of disease burden worldwide. According to World Health Organization estimates, NCDs are responsible for 74% of all deaths globally, with around 77% of premature deaths from NCDs occurring in low- and middle-income countries. This study aims to assess the lifestyle related health risk factors of non-communicable diseases among adults in Nepal, in which two- third of annual deaths are attributable to non-communicable diseases. Methods: A cross sectional study was conducted among adults in Morang district, Nepal. Data collection involved the assessment of the risk factors of obesity, smoking, alcohol consumption, inadequate fruits and vegetable consumption, inadequate physical activity, are raising blood pressure. Ethnical approval was obtained. Results: Two hundred forty participants participated in the study, of which the most prevalent risk factor was obesity (58.3%). Out of total participants, 41.6% had consumed tobacco, 31.2% had consumed alcohol, 41.6% had consumed inadequate fruits and vegetables, 30.4% had inadequate physical activity, and 29.1% had raised blood pressure. Similarly, education is statistically associated with lifestyle risk factors. Male participants of age above 40 years were found to be statistically associated with current tobacco and alcohol consumption. Conclusion: Health related risk factors are causes of non-communicable disease. Most of the participants had two or more risk factors for non-communicable disease. Education is significantly associated with all the risk factors among the participants.

Prevalence and patterns of tobacco use among young adults in India - does perceived stress play a role?

Background: Tobacco use among young people is a public health concern. Perceived stress among young adults as a determinant for tobacco use has not been extensively explored previously in India. Methods: A cross-sectional study was conducted among young adults aged 18-30 years across India. Data was collected using a self-administered, web-based, online questionnaire, on sociodemographic characteristics, tobacco use and its pattern, and the levels of perceived stress using the Perceived Stress Scale (PSS-10). Results: The prevalence of tobacco use in our study sample was 25.7% and the mean age at initiation of tobacco use was 20.71 years. Though tobacco use was significantly associated with male gender [aOR=2.26 (1.16-4.38), p=0.01], current alcohol consumption [aOR=13.73 (6.72-28.04), p=0.00] and having known smokers among family and friends [aOR=3.13 (1.39-7.04), p=0.01], there was no association between levels of perceived stress and tobacco use. Cigarettes/beedis were the most commonly used tobacco product, 27.58% of respondents reported using tobacco products daily or for more than half the days of the week and 48.27% of respondents started using tobacco out of curiosity. Seventy percent of users used tobacco during specific events like social gatherings and vacations while 57.47% used tobacco while meeting specific colleagues/ friends. Conclusions: We found no association between perceived stress and tobacco use. However, current use of alcohol and having knowledge about smokers among family and friends significantly determined tobacco use among our study population. This necessitates more holistic approaches towards behaviour change efforts for tobacco control.

Exploring the associations of tobacco smoking and serum cotinine levels with selected inflammatory markers in adults with HIV in South Africa

This study examined the associations between tobacco smoking and serum cotinine levels, an objective biochemical measure of tobacco smoke exposure, with markers of inflammation, i.e., interferon-gamma (IFN-γ), interleukin 10 (IL-10), interleukin 2 (IL-2) and tumour necrosis factor-alpha (TNF-α) in people living with HIV (PLWH).These specific markers were selected because of their hypothesised associations with smoking, PLWH and their outcomes. In a random sample of ≥ 18-year-old PLWH receiving care at 17 public healthcare facilities across the Western Cape Province in South Africa, data collection included self-reported smoking history, and serum levels of cotinine and selected inflammatory markers. The inflammatory marker data were log transformed because of the skewedness of their distribution. Linear regression models (1) adjusted for age and gender, and (2) fully adjusted for age, gender, current alcohol use, body mass index and CD4 counts were used to examine the associations between smoking tobacco or serum cotinine and inflammatory markers. Level of significance was p < 0.05. Among 749 PLWH who were mainly women (79%), the mean age was 38.5 (8.9) years and similar when stratified by smoking status. Serum cotinine levels exhibited a striking discrepancy, with a median of 154 ng/mL among current smokers, in stark contrast to the consistent median values of 10 ng/mL observed among past and never smokers. In regression models adjusted for age and gender, current smoking and frequent smoking were associated with lower IL-2 but higher TNF-α. Log-cotinine exhibited associations with IFN-γ, IL-10, and TNF-α, while cotinine levels ≥ 10 ng/mL compared to < 10 ng/mL were associated with higher IFN-γ and TNF-α. In fully adjusted models, log-cotinine and cotinine levels ≥ 10 ng/mL displayed significant associations with higher IFN-γ and lower IL-2. This study underscores the importance of investigating the interplay between smoking tobacco or serum cotinine levels with pro-inflammatory cytokines in PLWH. It signals the need for comprehensive research to unravel the potential synergistic impacts of smoking tobacco and HIV infection on chronic inflammation and immune dysregulation, shedding light on critical avenues for intervention and management strategies.

Examining the relationship between social well-being levels of health personnel and their perception of gender roles: a university hospital example

ABSTRACT The purpose of this research is to examine the relationship between the social well-being of healthcare professionals and their perception of gender roles. The correlational screening model was used in the research. The study group consisted of 247 healthcare professionals working in a university hospital. As a data collection tool in the research, the Social Well-Being Scale-Healthcare Professionals Version, Gender Roles Attitude Scale, and Demographic Data Form were used. Unrelated Samples t-test, One-Way Analysis of Variance, Pearson Product Moment Correlation Coefficient, and Multiple Linear Regression Analysis techniques were used to analyze the data. It was determined that the social well-being average of healthcare workers was 121.43 ± 24.46 and the gender role average was 99.48 ± 9.70. It was observed that the average social well-being of healthcare professionals differed at a statistically significant level according to family structure, length of service in the current institution, alcohol use, gender roles, gender, and profession (p < .05). As a result of the research, it was determined that there is a positive relationship between social well-being and gender roles. It was determined that gender roles, gender, length of service in the current institution and alcohol use status significantly predict social well-being.

Exploring the Association of Smoking and Alcohol Consumption with Presence of and Severe Coronary Artery Calcification.

Despite the majority of studies have identified smoking as a risk factor for coronary artery calcification (CAC), some studies have not identified this relationship. Differences on results reached by studies on the association of alcohol consumption with CAC exist. Moreover, studies have almost exclusively investigated the association between smoking and alcohol consumption independently. Whether an interaction effect of alcohol on the association of smoking and CAC exists has hardly been investigated. The data of 2431 adult patients who visited Fuwai Hospital, Chinese Academy of Medical Sciences from September, 2001 to December, 2023 and had Agaston coronary artery calcification score (CACS) reported were utilized. Patients who (1) underwent percutaneous coronary intervention, coronary bypass graft and heart transplantation, or (2) were complicated by acute medical conditions, chronic kidney disease or malignant neoplasms were excluded. Data from 1528 patients were eventually analyzed. Logistic regression was employed to investigate the association of smoking and alcohol consumption with presence of CAC and severe CAC. Interaction effects of alcohol consumption history on the association of current smoking and both presence of and severe CAC were examined. Smoking history was significantly associated with presence of CAC and severe CAC. Current alcohol consumption was also significantly associated with presence of CAC and severe CAC. After adjusting for confounders, alcohol consumption history demonstrated an interaction effect on the association of current smoking with both presence of and severe CAC. Using non-alcohol consumers not smoking at the time of the study as reference, current smokers with an alcohol consumption history suffered from an increased risk of presence of CAC and severe CAC. Both smoking history and current alcohol consumption were associated with presence of and severe CAC. Alcohol consumption history demonstrated an interaction effect on the association of current smoking with both presence of and severe CAC.

Oral health and chronic kidney disease: Findings from a descriptive survey in Lagos, Nigeria.

Background: Chronic kidney disease (CKD) is a global public health problem, characterized by a progressive and irreversible decline in renal functions, and affecting up to 22.3% of Nigerians. Oral diseases are increasingly recognized to have a bidirectional relationship with CKD, contributing to systemic inflammation, infections, protein-energy wasting, and atherosclerotic complications. Given this interconnectedness, we aimed to explore the relationship between CKD and oral conditions among LASUTH patients to better understand and address these co-occurring health issues. Methods: This descriptive observational study was conducted in the nephrology unit of LASUTH. Patients aged &gt;20 years with a diagnosis of CKD were enlisted and a validated questionnaire with the modified WHO oral health status proforma was utilized to record clinical data: Estimated Glomerular Filtration Rate (EGFR), End-Stage Renal Disease (ESRD), Creatinine and Urinalysis from medical records and oral examination findings, Oral Hygiene Index-Simplified (OHI-S), Gingival Index (GI), Community Periodontal Index of Treatment needs (CPITN), oral malodour, and Oral lesions. Multivariate logistic regression analysis was conducted with adjustments for covariates like age, alcohol use, and BMI to determine the association between oral diseases and CKD. The significance level (p) was set at 0.05, with a confidence interval (CI) of 95%. Results: A total of 200 patients at different stages of CKD were included. The age range was 22–83 years. The majority were aged 31-60 years (mean age 55.22 ± 14.35 years); 69% were males; 7% were current smokers while 12% currently drank alcohol; 27% had eGFR&lt; 15 mL/min/1.73m2 (ESRD); 27% had Creatinine values &gt;1.3mg/dl; prevalence of Gingivitis was 72%; periodontitis was 14% (CPI score ≥3: Pocket depth of ≥4 mm); and poor OHI was 22%. The commonest oral lesions were white lesions 2%, candidiasis 4.5%, hyperpigmentation 22%, oral ulcers 5%, hemorrhagic lesions 12.5%, and Oral malodor 74.5%. Multiple logistic regression analysis revealed significantly increased odds of ESRD among uneducated respondents (OR 1.194; CI: 0.832-1.713); those &gt;60years (OR: 1.129; CI:0.436-2.923); current alcohol drinkers (OR:1.125; CI: 0.281-4.409); and smokers (OR:2.328; CI: 0.27-20.289). The odds of low stimulated saliva flow rate (OR: 1.181; CI:0.768-4.512), oral malodor (OR:1.093; CI: 0.763-1.565), and periodontal disease (OR: 1.242; CI: 0.698-2.209) were also significantly higher among those with ESRD. Conclusion: Individuals with CKD and ESRD may have a higher prevalence of oral diseases and conditions. There were significantly increased odds of ESRD among uneducated respondents, those over 60, current alcohol consumers, and smokers. Additionally, the odds of low stimulated saliva flow rate, oral malodor, and periodontal disease was also significantly higher among those with ESRD. This relationship may also be bidirectional, highlighting the need for appropriate oral self-care and regular dental-care utilization in patients with renal disease. The findings underscore the need for integrated healthcare approaches that consider both oral and renal health, providing a foundation for further research and targeted interventions.

Socio-ecological factors associated with e-cigarette susceptibility and current use among Thai adolescents

International research documents the popularity of youth e-cigarette use and factors associated with consumption. However, less research has examined the behaviour in jurisdictions where such products are illegal. This study therefore investigated social and demographic factors associated with the use of e-cigarettes among youth in Thailand, where such products are prohibited. An online cross-sectional survey was conducted among middle and high school students (n = 6,111) to capture individual, interpersonal, organizational, and social factors potentially related to the behaviour. Multinomial logistic regression was used to assess associations with e-cigarette susceptibility and use. The prevalence of e-cigarette susceptibility was 15.9%, with 9.7% reporting current use. Risk factors, including lower GPA, current smoking, current substance use, and peer vaping, were associated with susceptibility (vs. non-susceptibility) and use (vs. susceptibility). Parental vaping was linked solely to current use, while middle school attendance, current alcohol use, exposure to e-cigarette use in school and exposure to online marketing, were linked to susceptibility. Negative attitude towards e-cigarettes and regular exposure to anti-e-cigarette activities in school were protective factors against both. High-risk perceptions and regular parental supervision were protective factors for susceptibility. Despite bans, a significant proportion of Thai youth engage in e-cigarette use or are susceptible to it. Unique factors influence susceptibility and use, highlighting the need for strengthening laws and adjusting prevention efforts.

Associations of Regular Internet Usage with All-Cause and Cause-Specific Mortality: A Prospective Cohort Study

ObjectivesThe impact of internet usage on mortality is not widely known. This study intended to investigate the associations between regular internet usage and the risks of all-cause and cause-specific mortality, while also ascertaining potential factors that may modify these correlations. DesignA community-based prospective cohort study. Setting and ParticipantsThe study included 21,481 individuals [mean (SD) age, 64.1 (11.0) years] from the Health and Retirement Study, with data collected between 2006 and 2020. MethodsThe Cox proportional hazards regression model was used to evaluate the associations between regular internet usage and the risks of all-cause and cause-specific mortality, adjusting for demographic factors, lifestyle behaviors, and other potential confounding factors. Moreover, we explored the association between daily hours of internet usage and the risk of outcomes. ResultsRegular internet usage was significantly associated with a lower risk of all-cause mortality (hazard ratio, 0.78; 95% CI, 0.74-0.83) and cardiovascular mortality (hazard ratio, 0.72; 95% CI, 0.64-0.82). No significant interaction effects were observed for age, sex, regular exercise, or current alcohol consumption (all P interactions > .05). Additionally, estimations for daily hours of usage indicated a U-shaped relationship with all-cause mortality. Adults who used 2.1 to 4 hours per day had the lowest risk; however, not all estimations showed their significance on account of the limited sample size. Conclusions and ImplicationsRegular internet usage was associated with a lower risk of all-cause and cardiovascular mortality, which may prompt consideration of the beneficial impact of internet usage on lifespan.

Drinking refusal self-efficacy- a positive effect of attending de-addiction clinic -survey report of South Indian Union territory hospital.

Introduction: Alcoholism is the most common psychiatric disorder that causes impairment in physical health, mental health,and social functioning. “Alcohol dependence syndrome (ADS) is characterized by a state, psychic, and usually also physical,resulting from drinking alcohol. Self-efficacy is an individual’s belief in his/her innate ability to achieve goals. The prevalenceof current alcohol use in Pondicherry is 9.5% for males and 20 % in total. However, more than 40% of alcohol users drinkalcohol in a dependent pattern in Pondicherry. The current study aimed to assess the self-efficacy of clients to quit alcohol.Methodology: In this descriptive cross-sectional study 97 participants were selected by a convenient sampling technique atde addiction clinic, JIPMER, Puducherry. The tools used for the study include socio-demographic variables, modified versionof drinking refusal self-efficacy questionnaire, which consists of 19 questions to assess their belief about the ability to resistalcohol in the various situation on a six-point Likert scale ranged from 1( I am very sure I would drink) to 6 (I am sure I wouldnot drink)The primary objective was analysed using descriptive and inferential statistics and the secondary objectives were analysedusing the chi-square test and Pearson correlation.Results: The result showed that among 97 study participants, the majority of them could resist (58.8%) alcohol during theirde-addiction follow up visit.Conclusion: Our study concluded that patients who regularly attend de-addiction clinic could resist alcohol consumption.There is still a need for health education and counseling to quit Alcohol.

Decreased prevalence of alcohol use and related sociodemographic factors in an urban district of Shanghai, China: Evidence from three cross-sectional surveys (2010–2021)

BackgroundAlcohol use contributes considerably to the global impact of disease. However, limited research has been conducted recently to explore the changes in the prevalence of alcohol use, especially in urban Shanghai, China. ObjectivesTo estimate the prevalence changes of alcohol use and explore related sociodemographic factors among urban residents of Xuhui district, Shanghai, China. MethodsUsing a multistage probability proportionate-to-size sampling method, three waves of household investigations via a structured questionnaire were conducted in Xuhui district, Shanghai, China, between 2010 and 2021. Data were collected by face-to-face interviews among residents aged 15 or older who responded to the 2010, 2015, and 2021 Health Status and Health Service Utilization Survey. Age and sex standardized prevalence of alcohol use was calculated, and the linear trend was tested using logistic regression models. Multilevel mixed-effects logistic regression models with robust covariance matrix estimators were used to estimate related factors of alcohol use. ResultsA total of 24 552 participants aged 15–109 years were included. The standardized overall prevalence of current regular alcohol use statistically declined from 8.8 % in 2010 to 5.5 % in 2021. This decreasing trend was statistically significant, especially among men aged 30–59 and ≥ 75 years old. However, the prevalence of overall alcohol use, regardless of frequency, increased from 19.6 % in 2015 to 24.0 % in 2021. Multivariate regression analysis showed that men had a significantly higher likelihood of regular alcohol use than women. Also, age was positively related to regular alcohol use, while education level was negatively related to this behavior. ConclusionsAlcohol use was still common, although a significant decreasing trend in the prevalence of regular alcohol use was observed overall, in this study population. The findings call for strengthened health education and alcohol control in the context of the harmful effects of alcohol use at any level.

Determinants Associated with COVID-19 Vaccination among Korean Adults: Based on Andersen's Model.

COVID-19 vaccination is a critical public health measure to control the pandemic, but disparities in vaccination uptake remain a concern. This study investigates the determinants of COVID-19 vaccination among Korean adults using the Andersen model. Data from 231,784 participants in the community health survey were analyzed using chi-square testing and logistic regression. The risk of non-vaccination was higher among those aged 19-64 (95% CI: 1.52-1.74), males (95% CI: 1.11-1.24), the unemployed (95% CI: 2.21-2.47), unmarried individuals (95% CI: 1.12-1.24), those with unmet healthcare needs (95% CI: 1.41-1.67), recipients of national basic livelihood guarantees (95% CI: 1.45-1.73), those with lower subjective health (95% CI: 1.20-1.30), individuals with depression (95% CI: 1.28-1.44), current smokers (95% CI: 1.13-1.30), and those skipping breakfast (95% CI: 1.04-1.16). Conversely, the risk was lower for those with less than a high school education (95% CI: 0.72-0.81), individuals with psychological concerns about infection (0.87, 95% CI: 0.82-0.92) or public criticism (0.91, 95% CI: 0.86-0.97), individuals with chronic diseases (95% CI: 0.64-0.72), and current alcohol consumers (95% CI: 0.52-0.58). These findings underscore the need for targeted intervention strategies and support systems to promote vaccination in vulnerable populations. Further research should explore the long-term impact of these interventions on vaccination uptake.

Contextualizing linguistic acculturation and alcohol use among Hispanic college students in the social digital environment.

Linguistic acculturation is a predictor of alcohol use among Hispanic college students, but existing linguistic acculturation measures do not capture language use in the social digital context (e.g., social media). Guided by erosion theory and past empirical findings, this study operationalized two dimensions of social digital linguistic acculturation (SDLA) and examined the interactive effects of SDLA with immigration generation-a demographic proxy for acculturation-in relation to alcohol use intentions and behaviors. Online questionnaires were completed by 246 Hispanic college students in central Texas between the ages of 18 and 29 (Mage = 21.0, SD = 2.4; 82.1% female) who reported current alcohol use. Measures included two dimensions of SDLA (SDLA-English and SDLA-Spanish) with items developed for this study and supported by exploratory factor analysis, immigration generation as a demographic proxy for acculturation, and three alcohol outcomes (intentions to use alcohol, alcohol consumption, and binge drinking). We specified three regression models in which immigration generation moderated the pathways between SDLA-English and SDLA-Spanish and each alcohol outcome. Contrary to hypotheses, lower rather than higher SDLA-English was related to greater intentions to use alcohol, greater alcohol consumption, and more frequent binge drinking when immigration generation was higher rather than lower. More aligned with expectations, lower SDLA-Spanish was related to more frequent binge drinking when immigration generation was higher. The link between SDLA and alcohol engagement is nuanced. This study's findings may be partially explained by acculturative stress in the context of social digital engagement, warranting further exploration. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Alcohol consumption and smoking history at time of diagnosis, and risk of colorectal cancer recurrence and mortality: Results from the ColoCare Study.

Findings from studies investigating the impacts of alcohol use and smoking on colorectal cancer (CRC) outcomes are inconclusive. This study aimed to investigate associations between alcohol use and smoking status at the time of diagnosis on recurrence and overall mortality among patients with CRC. The present study included 2,216 stage I-IV patients with CRC from the longitudinal multi-center ColoCare study, with available data on recurrence and CRC-specific mortality. Cox proportional hazards models adjusted for age, sex, race, ethnicity, stage, tumor site, treatment, comorbidities, body mass index, and study site were fit, with imputations for missing data. We observed 235 recurrences and 308 CRC-specific deaths over an average of 3 years of follow-up. After adjusting for confounders, current alcohol consumption and ever smoking, relative to not current consumption and never smoking, respectively, were not statistically significantly associated with CRC recurrence (Alcohol - HR: 0.95. 95% CI: 0.71-1.29; Ever smoking - HR: 0.98, 95% CI: 0.75-1.29) or CRC-specific mortality (Alcohol - HR: 0.95. 95% CI: 0.74-1.22; Ever smoking - HR: 0.98, 95% CI: 0.77-1.24). No associations were observed between alcohol and smoking at diagnosis and clinical outcomes in this well-annotated longitudinal cohort. Our cohort study reports no significant associations; however, limiting alcohol use and avoiding smoking are health behaviors recommended for CRC survivors for prevention of other cancers and chronic conditions.