For centuries, Turkic peoples have lived in close interaction, which contributed to the formation of similar cultural traditions, languages and customs. This has made them a unique and distinctive historical and cultural area on the map of Eurasia. The study of the interpenetration of cultural codes of the CIS countries of the Central Asian region becomes particularly relevant, as it allows us to identify the main trends and patterns of interference of interacting cultures.The novelty of the study lies in the methodological approach to the analysis of cultural codes of nations, according to which the interference of cultural codes is considered here as an instrument of cultural interpenetration, which reveals the specific relationship between cultural codes and national identity, as well as identifies the reasons for the universalization of cultural codes of border cultures.The purpose of this paper is to explore precisely those features of cross-border cultural interaction that fall under the description of cultural interference in its original sense, which implies spontaneous, uncontrolled cultural interpenetration resulting in the strengthening of some characteristics and weakening of others, in the absence of a dominant culture and deliberate influence on the qualitative characteristics of each of the interacting cultures. This publication offers an analysis of the spontaneity and uncontrollability of civilizational transformations of border cultures, acting as a natural process of interference of cultural codes. The research material is the cultural practices of the CIS countries of the Central Asian region.The main study measures used are conceptual and phenomenological analysis, axiological and analytical research techniques, method of classification analysis, etc.The study of the CIS countries of Central Asia revealed a number of coinciding elements of culture of these countries, indicating the presence of their common national cultural and civilizational identity, which stem not only from the cultural roots common to these peoples, but also a consequence of cultural interference and integration in the process of centuries of coexistence in the neighboring territories.