It is only in the last hundred years or so that crop monoculture has become predominant in industrialized agriculture for field and plantation crops. The reasons were for simplicity of planting, harvesting and other operations, which could all be mechanized, and for uniform quality of the crop product. However, monoculture produced severe disadvantages, such as vulnerability to diseases, pests and weeds, and yield instability, which necessitated, for example, the large-scale use of pesticides, fertilizers and growth regulators. To avoid or reduce some of the problems of monoculture, we need to introduce and manage diversity in better ways. At the highest level, species monoculture is difficult to change, at least in the short term. At the variety level, diversification is easy to manage, in the form of variety mixtures within the field. The idea of purposely blending different varieties of wheat is more than 50 years old and was first proposed and tested to reduce the impact of stem and leaf rust. More recently, this concept has also been expanded to look whether blends improved grain yield and/or grain quality. This article reviews the current knowledge about the mechanisms that account for disease reduction and yield increase in a variety of mixtures. It discusses the various determinants in the adoption of a variety of mixtures and the prospects for and challenges in using a variety of mixtures as a functional diversification strategy. Key words: Disease reduction, diversity, sustainable agriculture, wheat variety mixtures, yield stability. INTRODUCTION Wheat variety blends are seed mixtures of two or more pure varieties. Cultivar mixtures refer to mixtures of cultivated varieties growing simultaneously on the same parcel of land with no attempt to breed for phenotypic uniformity (Mundt, 2002). Wolfe (1985) defined cultivar mixtures as mixtures of cultivars that vary for many characters including disease resistance, but have sufficient similarity to be grown together. Compared to the modern monoculture model, blending wheat varieties is a different approach. Each wheat variety has susceptibilities that can cause fluctuations in yield. For example, some varieties are highly disease resistant but may respond poorly to drought or a variety that is fairly cold-hardy may succumb to certain insect pests. In any environment where stresses occur unpredictably, combining pure varieties that have complementary strengths can help stabilize yields (Cowger, 2007). Variety and species mixtures are not only being used extensively in small-scale subsistence agriculture worldwide but also in large-scale systems. Cultivar blends have been used extensively in small grain production in several European countries (Wolfe, 2001). Currently, 6 to 15% of the wheat production area in the states of Washington, Oregon, and Kansas is planted to blends every year (NASS, 2007). Approximately 17% of the 644 000 ha of soft white common winter wheat seeded in Washington in 1999 consisted of mixtures (WASS, 1999). Part of the mixture production is for animal feed; however, cereal cultivar mixtures in Switzerland, Poland and the US are used for bread and beer production. Most interesting is the fact that the highest quality coffee of Colombia is almost all produced in cultivar mixtures to protect the coffee from the coffee rust disease. These mixtures are perennial and have been successful since 1982 on a large scale (Wolfe, 2001). Superiority of cultivar
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