Cukurova University Research Articles

Postpartum Depression Levels in Women After the Application of Assisted Reproduction Techniques and Their Affecting Factors

Objective: This study was carried out to determine postpartum depression levels and their affecting factors in women who became women after the application of assisted reproductive techniques. Methods: The study is descriptive and cross-sectional and was conducted with mothers (n=93) who had babies as a result of treatment at the infertility clinic of Cukurova University Hospital. Research data were collected using the “Personal Information Form” and “Edinburgh Postpartum Depression Scale (EPDS)”. In the analysis of the research data, descriptive statistics, independent samples t-test, Kruskall Wallis and Mann Whitney U test were employed. Results: The EPDS mean score of the women in the study was determined to be 18.22± 3.22 and 94.6% of them were at risk for postpartum depression. Statistically significant differences were found between the EPDS mean score of the mothers and the gender of the baby they want to have, experiencing anxiety, and sharing problems with their spouse (p0.05). Conclusion: It was determined that mothers who have a baby as a result of infertility treatment are at risk for postpartum depression. Although a healthy outcome of pregnancies obtained as a result of treatment is eagerly awaited by the mothers, it also poses a risk for postpartum infertile mothers.

Clinical experience with ceftazidime/avibactam for the treatment of extensively drug-resistant or pandrug-resistant Klebsiella pneumoniae in neonates and children.

Klebsiella pneumoniae is a significant cause of healthcare-associated infections, resulting in high morbidity and mortality rates due to limited treatment options. In this study, we aimed to evaluate the treatment outcomes and the safety of Ceftazidime-avibactam in infections caused by extensively drug-resistant or pandrug-resistant Klebsiella pneumoniae in pediatric patients. This study included pediatric patients who received ceftazidime-avibactam treatment due to extensively drug-resistant or pandrug-resistant Klebsiella pneumoniae infections, monitored in the pediatric intensive care, neonatal intensive care, and pediatric wards of Cukurova University Faculty of Medicine between 2022 and 2023. Patients' microbiological responses, clinical responses, medication side effects, and 30-day survival rates were evaluated. Eleven pediatric patients were included in the study, of whom nine were male (81.8%). The median age at the initiation of ceftazidime-avibactam treatment was 15months (range: 14days-183months). Sepsis was diagnosed in 9 patients (81.8%). Two premature infants (27 and 35weeks) were admitted to the neonatal ICU. Regarding the Klebsiella pneumoniae strains, 10 (91%) were extensively drug-resistant (XDR), and 1 (9%) was pandrug-resistant (PDR). Eight strains (72.7%) were carbapenem-resistant, and 9 (81.8%) were colistin-resistant. Microbiological response was noted in 8 patients (72.7%), clinical response was evident in 6 patients (54.5%). The 30-day survival rate was 54.5%, with six patients surviving. In our study, ceftazidime-avibactam has been identified as a significant treatment option for resistant Klebsiella pneumoniae infection in critically ill children and premature infants with sepsis and organ failure, and it has been found to be well tolerated.

Impact of Vermicompost and Different Plant Activators on Yield and Some Quality Parameters in Pumpkin (Cucurbita pepo L.)

In addition to being used as a snack, pumpkin seeds are an industrial product. It also has the potential to be used in the food, pharmaceutical, and cosmetic industries. Seed yield and quality are traits of economic importance. This study aims to determine the effect of vermicompost and different plant activators on the yield and some parameters of the pumpkin's quality. For this purpose, three plant activators [(ISR-2000 (I), Symbion-Vam (S), and Green-Miracle (G)] together with vermicompost (V) have been used. The experiment was conducted in the field of the Cukurova University Pozantı Agricultural Research and Application Center, Turkey. A total of 8 applications were made. Conventional fertilizer (CF) application was determined as the control group. The results showed that the applications increased the snack pumpkin's fruit, seed yield, and quality. The highest fruit and seed yield was obtained from CF (37.2 t ha-1, 101.42 g-1m2) application, followed by V+I (27.1 t ha -1, 80.09 g-1m2) application. Additionally, CF applications resulted in the highest fruit width (14.82 cm), length (23.31 cm), seed width (10.21 mm), and length (20.66 mm) of internal weight (74.33 %) measurements. Regarding mineral element and phenolic content, higher results were obtained when vermicompost and plant activators were combined. According to the study results, different doses of vermicompost may be recommended as an alternative to conventional fertilizer application in future studies.

Exploring the Impact of Cytogenetic Abnormalities on Treatment Responses and Survival Outcomes in Multiple Myeloma: A Single-Centre Experience of 13 Years of Follow-Up.

(1) Background: The introduction of novel therapies has led to a considerable evolution in the management of Multiple Myeloma, and chromosomal abnormalities predict the success of treatment. We aimed to characterize cytogenetic abnormalities for risk stratification in the patient population and to evaluate the predictive and prognostic value of the specified abnormalities in distinct treatment modalities. (2) Methods: This study included patients with Multiple Myeloma who applied to the Internal Medicine Clinic of the Cukurova University Faculty of Medicine. Between 2010 and 2023, 98 cases with cytogenetic abnormality data were identified. We analysed the effects of cytogenetic abnormalities on survival and response rates to first chemotherapies. (3) Results: P53 del was the most prevalent abnormality, and t(11;14) was the most common translocation. There was no significant difference in the mean survival and treatment response rates for specific cytogenetic abnormalities. When chemotherapies based on lenalidomide were initiated, patients' life-death statuses differed significantly from those of treatments without lenalidomide. Regardless of the type of chromosomal aberration, lenalidomide-based treatments independently enhanced average survival 14-fold, while there was no significant difference in overall survival among treatments. (4) Conclusions: In individuals with cytogenetic abnormalities, lenalidomide-based treatments should be started regardless of the chemotherapy to be used for the condition.

Factors Associated with Screen Addiction in Adults: A Prospective Study

Screen addiction is a common public health problem that causes significant harm to both individuals and society. This study’s primary purpose is to examine the factors associated with screen addiction and to propose a sustainable solution to screen addiction. This research was conducted on staff who work at Cukurova University. Phone addiction, internet addiction and physical activity level were evaluated with Smartphone Addiction Scale-Short Form (SAS-SF), Internet Addiction Scale (IAS), and International Physical Activity Survey Short Form (IPAQ-SF), consecutively. Craniovertebral angle was measured with a goniometer and shoulder protraction was measured with a tape measure. The study group consisted of 189 individuals (111 women and 78 men). The mean age was 44.15 ± 11.25 years (min: 23, max: 60). The addiction level was determined to be higher in the sedentary individuals. Phone and internet addiction is statistically higher in sedentary individuals than in individuals with sports habits (P

Investigation of Patient Safety Attitudes of Operating Room Staff

Operating rooms are one of the most chaotic work environments in a hospital. Patient-safety measures must be followed to obtain standardization in health care in the operating rooms. This study was conducted to investigate the patient safety attitudes of the staff working in operating rooms.
 The study was conducted using a descriptive and cross-sectional design with staff working in central operating rooms between February 2017 and October 2017 in Balcali Hospital of the Medical Faculty of Cukurova University, and in Adana Numune Training and Research Hospital. The population of the study consisted of healthcare staff working in the operating room units. Rather than selecting a sample from the population, reaching the whole population was aimed. 254 people who accepted to participate in the study, and who met the inclusion criteria, were included in the study. Staff information forms for collecting demographic data of the staff, and the Safety Attitudes Questionnaire (SAQ) for assessing patient safety attitudes of the staff, were used to collect the data. SPSS version 20 software was used to analyze the data. The results were interpreted using a 95 % confidence interval and a p < 0.05 significance level.
 The mean scores of the SAQ were as follows; the mean total SAQ scores were 49,58 ± 12,67, the scores for the teamwork climate dimension were 58,52±13,63, the scores for the job satisfaction dimension were 59,82±22,41, the scores for perceptions of management dimension were 44,35±22,99, the scores for safety climate dimension were 50,97±15,21, the scores for working conditions dimension were 51,35±25,01, and finally, the scores for stress recognition dimension were 36,83±16,14. 
 The results suggest that the patient safety attitudes of the staff working in the operating rooms were at an intermediate level. Providing necessary education and raising awareness are suggested to improve patient safety attitudes

Congenital Toxoplasmosis and Long-term Outcomes.

Congenital toxoplasmosis (CT) can have severe early and late sequelae in children. In this study, we aimed to evaluate the demographic, clinical, treatment characteristics of patients diagnosed with congenital Toxoplasma infection and to highlight the long-term complications of the patients. Patients with CT were included in this study who were followed between 2010 and 2022 in Cukurova University Medical Faculty Hospital. Demographic, clinical and treatment characteristics were searched retrospectively. In the diagnosis of maternal and CT, Toxoplasma IgM, IgG, IgG avidity, T. gondii polymerase chain reaction tests were used along with clinical and symptoms. Eighteen children (two twins) with CT and their mothers (n=16) were included in the study. Median age was 1 month. Ten (55.5%) of the children were male. CT diagnosis was made during pregnancy in 7 mothers (resulting in 8 babies) and postnatally in 9 mothers (resulting in 10 babies). The mothers of 5 (31.1%) babies with CT received spiramycin treatment during pregnancy. Three (60%) of 5 pregnant women who received spiramycin were diagnosed in the first trimester, 4 (80%) of the babies did not have any sequale and only 1 (20%) had microphthalmia. Ocular involvement was the most common presentation of the disease occured in 10 patients (55.5%), hydrocephalus and intracranial calcification developed in five patients (27.7%). Hearing loss developed in 2 (11.1%) patients. During the follow-up period, seizures developed in 3 patients (16.6%), microcephaly in 2 patients (11.1%), and neurodevolopmental retardation in 7 patients (38.8%), two of the patients had severe mental retardation. One (5.5%) patient with hydrocephalus died at 36 months of age due to complications after ventriculoperitoneal shunt application. In our study, we observed severe sequelae in vision, hearing, and neurodevelopmental aspects in children diagnosed with CT at birth and during follow-ups. Early diagnosis and treatment of infants, along with the detection of Toxoplasma infection during pregnancy, are essential in preventing severe sequelae that may arise due to CT.

Clinical characteristics of children with asthma exacerbations: a cross-sectional descriptive study

Aim In this cross-sectional descriptive study, we aimed to determine the clinical characteristics of children admitted to a tertiary hospital with asthma exacerbations in a city in southern Turkey where aeroallergens are common and to determine how these characteristics affect the severity of exacerbations. Methods Data from a cross-sectional analysis of children with asthma exacerbations who were followed up at the Cukurova University Medical Faculty Pediatric Emergency Department (ED) and Pediatric Allergy & Immunology inpatient clinic were retrospectively analyzed. The study included 106 children who were diagnosed with asthma and did not have any additional comorbidities. In a comparative analysis, the clinical characteristics and laboratory parameters of children with mild/moderate and severe exacerbations were examined. Results While 81.1% of the patients had mild/moderate exacerbation, 18.8% had severe exacerbation. Additional atopic disease, Alternaria positivity in the skin prick test, the frequency of exacerbations in the previous year, Streptococcus pneumoniae infection, and the rate of noncompliance with treatment were significantly higher in children with severe asthma exacerbations. PEF, FEV1, and FEV1/FVC values were considerably lower in patients with severe exacerbations. Conclusions Bacterial infections, presence of atopic disease, Alternaria exposure, low spirometric measures, number of exacerbations in the previous year, and low rate of treatment adherence may be relevant in predicting the severity of asthma exacerbations.

Response of cowpea (vigna unguiculata l.) to organic and chemical fertilizer applications on grain yield and yield components

Grain of cowpea are used for human diet and its grain contains high protein, minerals and vitamins. Cowpea was also used as hay, silage, green forage, grain fodder for feed livestocks. The experiment was conducted under irrigated conditions in the experimental area of Field Crop Deparment, Faculty of Agriculture, Cukurova University, Balcalı, Adana, Turkiye. The growing period covered throughout 2021 and 2022. The field experiment was organized in split plots based on randomized complete blocks design with three replication. Two registered cultivars (Karagöz ve Akkız) were used as a research material. In this experiment the main plots were cultivars and sub-plots were application of fertilizer. Treatments were: control (no fertilizer), solid leonardite, liquid leonardite, basal chemical dose + solid leonardite, basal chemical dose +liquid leonardite, basal chemical fertilizer + additional N fertilizer. Basal chemical dose was application of 40 kg N ha-1 and 100 kg N ha-1 P2O5 (Di ammonium phosphate or DAP) before sowing as recommended chemical fertilizer. Addition chemical dose was application of 80 kg N ha-1 (Ammonium sulfate) over the basal dose at the seedling stage. Rhizobia inoculant was not applied during the field experiment. Akkız seed yield was significantly higher in application of liquid leonardite fertilizer and the combination of basal chemical fertilizer + liquid leonardite fertilizer with 1656 and 1533 kg ha-1 respectively, compared to other treatments. The grain yield in the control plot was the lowest in both cultivars. As a result, applying liquid leonardite fertilizer into the soil before sowing can be useful for grain production in cowpea.

Fibular notch morphometry and its clinical importance on dry bones.

The aim of the present study was to determine the morphometric characteristics of the fibular notch (FN). This study was carried out with 76 dry adult tibial bone specimens (right 38, left 38) with unknown age and sex collected from the Department of Anatomy, Cukurova University, Adana. The mean width of the FN was 23.04 ± 2.02 mm; the mean depth of the FN 3.63 ± 0.83 mm; the mean height of the FN was 41.76 ± 4.01 mm. The mean anterior facet length and posterior facet length was found to be 10.44 ± 1.94 mm and 13.93 ±1.63 mm, respectively. The mean value of the angle between the anterior and posterior facets was found to be 140.56° ± 11.72. The mean value of the angle between the anterior surface of the tibia and the intertubercular line was 75.5° ± 5.47. No statistically significant differences were detected between the right and left sides for all measurements. It is considered that knowing the morphometric and anatomical characteristics of the fibular notch in detail will help radiologists evaluate the talocrural region. It is also considered that these data will guide surgeons and help determine the appropriate size for ankle reconstruction operations.

Egg quality characteristics of sussex chickens reared under the housing conditions of Cukurova University farm

This work was conducted to evaluate the egg quality characteristic of Sussex multi-purpose chickens reared under the housing conditions of the Cukurova University Farm. A total of 81 Sussex chickens from the Poultry and Research Unit of Cukurova University were used in this study. The external and internal egg-quality paraemeters were determined using 30 eggs on both the 28th and 33rd weeks of egg production cycle. The egg quality parameters measured were the Haugh unit, breaking strength, yolk color, shell thickness, egg weight, shape index, shell weight, albumen index, yolk index, and albumen pH. The egg weight, albumen index, yolk index and Haught unit were 57.89±3.99g, 9.44±2.07, 43.22±3.57 and 84.85±8.87 respectively. The shape index, shell thickness, shell weight, shell breaking strength and albumen pH were %75.32±2.11, 0.338±27.84mm, 5.903±0.645g, 3.825±1.065 kg/cm2 and 7.84±0.18 respectively. The yolk color, L, a, b and E values were 55.85±7.02, 13.91±3.33, 47.18±7.90 and 74.99±5.96 respectively. It was concluded that the external and internal egg-quality parameters of Sussex chickens reared under the housing conditions of the Cukurova University Farm were between the normal range.

Cholesteatoma Surgery With Three Different Methods: A Clinical Study For Recidivism Research

Introduction: The study aimed to determine the rates of recidivistic disease after primary surgery, localization of cholesteatoma, pathologic findings detected during the operation, and the additional surgical procedures performed in patients with chronic otitis media with cholesteatoma. Materials and Methods: Three hundred forty-five patients suspected of chronic otitis media with cholesteatoma searched their files and operation notes in Cukurova University Hospital between January 2010 and January 2020 retrospectively. Three surgical techniques were applied: Canal Wall Down (CWDM), Canal Wall Up (CWUM), and Radical (RM) mastoidectomy. Cholesteatoma localization, ossicular system status, condition of the facial canal, semicircular canal defects, tegmen defect, tympanoplasty, and whether hearing reconstruction is performed were investigated. In follow-up, revision surgeries were performed on 61 patients with suspicions of recidivistic disease. The revision surgery region was where cholesteatoma was detected, and the condition of the ossicles was investigated. Patients' demographic characteristics, follow-up time, the recidivism rate in surgical method, cholesteatoma localization in the first surgery, and cholesteatoma localization in revision surgery were compared. Results: 27.2% of 345 patients were CWUM, 23.5% were CWDM, and 49% were RM. Cholesteatoma localization was 60.9% of them in mastoid cavities, 59,4% of them in the attic and epitympanum, 56,2% of them in the middle ear, and 12,8% of them in only sinus tympani and facial recesses. Patients were followed for a mean of 36 months. In the follow-up period, revision mastoidectomy was performed for ten patients with recidivistic disease. Revision rates after CWUM were 62,3%, revision rates after CWDM were 9,8%, and revision rates after RM was 27,9%. Conclusions. The choice of surgical procedure is an essential parameter in forming a recidivistic disease. Especially in open technical surgeries (CWDM and RM), the risk of recidivistic disease is significantly lower than that of closed technical surgeries (CWUM). Keywords: Cholesteatoma, recidivistic disease, ossicle erosion, radical mastoidectomy

Healthy food choice education for undergraduate university students: a quasi-experimental design.

A healthy diet is necessary in every period of life to protect health and prevent diseases. The main purpose of nutrition education is to convey the importance of adequate-balanced nutrition and healthy food choice in maintaining health. This study was conducted to determine the food choice behaviors of the students who took (n=95) and did not take (n=145) the "Healthy Food Choice" course at Cukurova University. The "Healthy Food Choice" course was given as an elective in the fall semester of the 2021-2022 academic year. The data were collected between April and June 2022 through a demographic questionnaire, the healthy food choice test, and the perceived stress scale (PSS). Sensory appeal and health were found to be the most important determinants, while familiarity and ethical concern were the least important factors in the food choice of the students who took the course. In the control group, sensory appeal and price were the most important determinants, while ethical concern and weight control were the least important factors. Health, natural content, and weight control were more effective in food choices of the students who took the healthy food choice course compared to the controls (p<0.05). Also, PSS score was associated with the importance of the food price positively in the case group and negatively associated with natural content in the controls. Furthermore, the present study showed that BMI was positively associated with weight control and familiarity in the HFC group and negatively associated with natural content in the control group. Giving the HFC course to university students showed positive results in terms of food choice behaviors.

The effect of perioperative cardiac risk factors on postoperative outcomes in the elderly patients undergoing hip replacement surgery

Purpose: Cardiac risk factors are among the most important determinants of postoperative outcomes in elderly surgical patients. This study aimed to determine the effect of perioperative cardiac risk factors on postoperative adverse outcomes in elderly patients undergoing total hip replacement surgery.&#x0D; Materials and Methods: Patients aged 65 and older who underwent total hip replacement surgery at Cukurova University Hospital between 2014 and 2019 were analyzed retrospectively. The primary outcome measures were postoperative adverse outcomes and mortality rate.&#x0D; Results: Two hundred twenty-three patients with total hip replacement surgery within five years of experience in our hospital were screened. 34.5% had postoperative cardiac, pulmonary, cerebral, and infectious morbidity and systemic inflammatory response syndrome, and the in-hospital mortality rate was 2.2%. On multivariate analysis, perioperative risk factors associated with postoperative adverse outcomes included American Society of Anesthesiologists (ASA) II physical status (aOR 5.63, 95% CI 1.75-18.11), preoperative poor functional capacity (aOR 9.50, 95% CI 3.14-28.79), traumatic fracture (aOR 2.75, 95% CI 1.22-6.24), preoperative anemia (aOR 2.15, 95% CI 1.05-4.37), and prolonged surgery (aOR 1.02, 95% CI 1.01-1.02).&#x0D; Conclusion: A significant relationship was determined between preoperative poor functional capacity, pre-existing anemia, traumatic hip fracture, ASA II physical status, prolonged case duration and the risk of postoperative complications in elderly patients undergoing total hip replacement surgery.

Forensic age estimation with ankle MRI: Evaluating distal tibial and calcaneal epiphyseal fusion

Forensic authorities often request age estimation from forensic experts, particularly in cases related to sexual abuse, child pornography, illegal migration, marriage, etc. The most commonly used method in this regard is radiological methods. Because of the potential dangers of radiation exposure outside of clinical indications, new researches are focusing on non-ionizing and non-invasive technologies. This study aimed to demonstrate the applicability of age estimation in living individuals from ankle magnetic resonance images as a non-ionizing method, and to determine whether it is compatible with individuals' real ages and to establish a database. Ankle MRI images of patients aged between 7 and 26 years who applied to the Cukurova University Faculty of Medicine Balcali Hospital between January 2011 and December 2020 were retrospectively evaluated. A six-stage staging method proposed by Lu et al. was applied to the distal tibial and calcaneal epiphyseal ossification points by examining ankle MRI images of a total of 331 patients, 197 males and 134 females. In the study, images obtained from a sagittal section fast spin echo T1-weighted sequence, with a section thickness of 3–4 mm, were evaluated. As a result of the study, Stage 1 in both distal tibial and calcaneal epiphysis was observed only in patients under 18 years of age in both sex. In males, stage 2 in distal tibial epiphyseal ossification was observed under 18 years of age, except for one case, and stage 5 in both distal tibial and calcaneal epiphyseal ossification was observed in almost all cases over 18 years of age in males. According to the results of our study, magnetic resonance imaging was found to be a non-ionizing method that could be used in addition to other radiological methods aimed at determining the 18-year age limit in age estimation. Multicenter, comparative, and prospective studies conducted by experienced researchers are needed to enable the routine use of MRI in age estimation.

Investigation of Relationship between Playing the Piano Capability and the Second-to-Fourth Digit (2D:4D) Ratio

BACKGROUND&#x0D; In the field of piano playing, the suitability of physical characteristics of individuals, especially at the beginner level, is one of the first criteria considered important for educators. In many studies examining the physical fitness of individuals in sports fields, the importance of the relationship between physical fitness and ability has been revealed. In addition, there are studies examining the physical fitness for playing any instrument in the field of music. However, studies examining the physical characteristics of beginner piano players are very limited. Therefore, the purpose of our study was to investigate the relationship between the physical properties of the hand and the ability to play the piano. In addition, our study is the first to examine the relationship between the second digit and fourth digit ratio and the state of being successful in playing the piano. We also intended to contribute to the literature on this subject.&#x0D; METHODS&#x0D; Among the students who participated in the ballet and piano special talent exam held at Cukurova University State Conservatory in the 2013 and 2015 academic years, students who participated in the piano special talent exam were included in the study. In this exam, the suitability of the candidate to play the piano was evaluated in terms of musical and physical competence. In our study, the second digit and fourth digit length parameters, which include the physical characteristics of the hand, were evaluated. Length measurements were made with a digital display caliper. Students between the ages of 8 and 11 who participated in the piano talent exam were divided into two groups as those who were successful and those who were unsuccessful in the talent test.&#x0D; RESULTS&#x0D; The number of successful girls was 20 and the average length of the second digit 6.00±0.50 cm, mean fourth digit length; 5.90±0.40 cm, the number of unsuccessful girls was 17, the average of the second length; 5.98±0.48 cm, and the mean fourth digit length was 5.89±0.48 cm. The number of successful men was 15, and the mean length of the second digit; 6.55±0.36 cm, mean fourth digit length; 6.61±0.47 cm, the number of unsuccessful men was 17, the mean length of the second digit; 6.46±0.52 cm, mean fourth digit length; 6.52±0.55 cm were found.&#x0D; CONCLUSIONS&#x0D; There was no significant relationship between the piano playing ability and the second digit and fourth digit length ratios. We think that this is due to the evaluation of factors such as the level of development of the sensorimotor and neuromuscular system, the level of auditory proficiency, and coordination, not only with the anatomical suitability factors, in the scoring of the talent exam. Therefore, we can say that being successful in playing the piano does not depend only on digit lengths.

COVID-19 pandemic and burnout: factors associated with burnout levels among healthcare workers

Purpose: This study investigated the psychosocial and demographic factors influencing burnout levels among healthcare workers during the coronavirus disease 2019 (COVID-19) pandemic.&#x0D; Materials and Methods: A cross-sectional and descriptive study was performed on a total of 418 healthcare workers from Cukurova University Faculty of Medicine, Balcalı Hospital in Turkey. While the participants were selected randomly, a personal information form consisting of 33 open- and close-ended questions, Coronavirus Anxiety Scale, the Maslach Burnout Scale and the Beck Burnout were applied.&#x0D; Results: They were 418 healthcare workers aged 19-63 (mean= 35.51±9.38), 284 of whom were 61.8% female, 132 (31.7%) of whom were male, and 2 (0.5%) of whom refused to specify their gender. The study found that emotional exhaustion and depersonalization scores were significantly positively correlated with COVID-19 anxiety scores and Beck anxiety scores in healthcare workers, while personal accomplishment scores were significantly negatively correlated with these variables. The study also revealed that COVID-19 anxiety, Beck anxiety, being female, being young, being unmarried, having children, being diagnosed with COVID-19, having a chronic illness, and working more hours per week were all contributing factors to burnout. &#x0D; Conclusion: Both during and after the COVID-19 pandemic, it is very important to provide various forms of psychological support and make arrangements to address factors that can impact the burnout of healthcare professionals.

Yield and Nutrient Contents of Wheat, and Changes in Selected Soil Properties after 23 Years of Phosphorus Fertilizer Application

Effective nutrient and fertilizer management practices play a pivotal role in sustaining agriculture and mitigating the effects of climate change. These practices have a direct influence on soil fertility and crop productivity. This study investigated the long-term impacts of different phosphorus (P) fertilizer doses (0, 50, 100, and 200 kg P2O5 ha-1) on biomass yield and grain nutrient levels of wheat crops as well as on selected soil properties. The experiment was established in 1998 at the Research Center of Cukurova University in Adana, Southern Turkey. The wheat seeds were sown in October 2020 and harvested in May 2021. The experimental design was a randomized complete block, comprising 12 plots and replicated three times. Soil samples were collected at depths of 0-15 cm and 15-30 cm and subsequently analyzed for total carbon, organic carbon (OC), total nitrogen (TN), and the number of mycorrhizal spores. At harvest, wheat plant samples were collected for evaluating total dry biomass, grain yield and concentrations of potassium (K), zinc (Zn), total carbon (C), and total nitrogen (N) in the grain. The result showed that there was a linear increase in the total dry biomass of wheat, however, grain yield started to decline at P200. The wheat grain nutrient concentrations did not differ significantly across P doses, except for higher concentrations of Zn and K at P50 and higher values of grain C and N at P100. However, there was a linear decrease in Zn concentration as the applied P dose increased. The soil OC and soil TN at 0-5 cm were significantly changed relative to the control. The highest levels of soil OC and TN were observed at P100. The number of mycorrhizal spores did not significantly change with the P dose, but a decreasing trend was observed at higher doses. In conclusion, based on the observed parameters of wheat grain yield, total biomass production, grain nutrient concentrations, and soil OC storage, the application of 100 kg P2O5 ha-1 outperforms other P doses. However, the agronomic efficiencies, soil nutrient balance, and environmental effects of the applied P dose require more research.

Some Yield and Quality Properties of Endemic Origanum husnucan-baserii Grown in Different Ecological Conditions

Origanum husnucan-baserii is an endemic species naturally found in Ermenek district of Karaman and Antalya. This study was carried out to determine the agronomic and chemical components of the O. husnucan-baserii, which grows naturally in Ermenek (South of Turkey). The experiment was carried out in the garden of Ermenek Vocational School for 3 years in 2014, 2015 and 2016, and in the research areas of Field Crops Department of Cukurova University for 2 years in 2015 and 2016 (O. husnucan-baserii plant grown in Adana vegetation could not be harvested in the first trial year (2014), since flowering did not occur). O. husnucan-baseri grown in Ermenek, 3-year plant height is between 79.00-74.61 cm, average 74.61 cm, the number of branches between 29.07-27.14 units/plant, average 28.29 units/plant, fresh herbage weight between 731.5-233.7 g/plant, average 463.40 g/plant, dry herbage weight between 344.3-84.14 g/plant, average 193.31 g/plant, dry leaf weight between 163.60-34.30 g/plant, average 83.70 g/plant, essential oil ratio between 0.92-0.16 %, the average was determined as 0.63%. The main component of the essential oil, p-cymene, was obtained as 81.29% in the first year, 81.39% in the second year and 66.62% in the third year. The plant height of the plants grown in Adana is between 84.67-61.57 cm, the average is 73.12 cm, the number of branches is between 37.00-25.71 units/plant, the average is 31.36 units/plant, the fresh herbage weight is between 304.33-190.90 g/plant, the average is 247.62 g/plant, dry herbage weight between 113.66-80.43 g/plant, average 97.05 g/plant, dry leaf weight between 72.00-31.40 g/plant, average 51.70 g/plant and essential oil ratio between 1.26-0.98%, the average was determined as 1.12%. The rate of p-cimen, the main component of the essential oil, was determined as 69.52% in the first year and 76.38% in the second year. Some characteristics such as plant height, fresh and dry grass weights were higher in Ermenek than Adana results. In terms of essential oil content, plants cultivated in Adana had higher values. In this case, it would be more appropriate to choose a region according to the purpose of cultivation.

MP67-19 THE EFFECT OF CRIBRIFORM PATTERN ON ONCOLOGIC OUTCOMES IN SURGICAL MARGIN POSITIVE PATIENTS AFTER RADICAL PROSTATECTOMY

You have accessJournal of UrologyCME1 Apr 2023MP67-19 THE EFFECT OF CRIBRIFORM PATTERN ON ONCOLOGIC OUTCOMES IN SURGICAL MARGIN POSITIVE PATIENTS AFTER RADICAL PROSTATECTOMY Mutlu Deger, Mubariz Aydamirov, Nebil Akdogan, Ismail Onder Yilmaz, Seyda Erdogan, Yildirim Bayazit, and Volkan Izol Mutlu DegerMutlu Deger More articles by this author , Mubariz AydamirovMubariz Aydamirov More articles by this author , Nebil AkdoganNebil Akdogan More articles by this author , Ismail Onder YilmazIsmail Onder Yilmaz More articles by this author , Seyda ErdoganSeyda Erdogan More articles by this author , Yildirim BayazitYildirim Bayazit More articles by this author , and Volkan IzolVolkan Izol More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003330.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To investigate the relationship between cribriform pattern (CP) and biochemical recurrence-free (BCR) and metastasis-free survival in surgical margin (SM) positive patients after radical prostatectomy (RP). METHODS: The data of 421 patients who underwent RP surgery for prostate cancer (PC) between February 2011 and December 2019 in our clinic were retrospectively analyzed. Ninety-five patients with surgical margin positivity (SMP) were included in the study. Presence of CP in the primary tumor and additional SM parameters (localization, laterality, number, length, presence of CP in (+) SM, Gleason grade (GG)) were examined. Risk factors for BCR were investigated. The primary endpoint of the study was the effect of CP on BCR-free survival, and the secondary endpoint was the effect on metastasis-free survival. Declaration of Helsinki and additional approval was obtained from the Ethics Committee of Cukurova University, Medical Faculty, Adana, Turkey (number of meetings: 125; number of decisions: 81). RESULTS: CP was found in the primary tumor in 44 (46.3%) patients, and in both the primary tumor and (+) SM in 11 (11.6%) patients. In the follow-ups, 30 (31.6%) patients developed BCR and 8 (8.4%) patients developed metastasis. Post-RP Gleason score (GS), pathological tumor stage, and lymph node invasion (LNI) were statistically significantly associated with the presence of CP (p=0.001, p=0.001, and p=0.008, respectively). In multivariate Cox regression analysis, both the presence of CP in the primary tumor (HR=1.84, 95% CI=0.98-3.81; p=0.025) and the presence of CP in (+) SM (HR=1,4, 95 %CI=0.42-4.63; p=0.039) was found to increase BCR statistically significantly. The time to metastasis was statistically significantly shorter in patients with CP (101.3 months vs. 122.9 months; p=0.01). The time to BCR was similar in patients with CP in the primary tumor and those with CP in (+) SM (71.5±7.6 and 78.1±7.6, respectively; p=0.321). CONCLUSIONS: CP is associated with poor histopathological outcomes and is an independent histopathological predictor of BCR-free and metastasis-free survival in patients with SMP. Source of Funding: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e950 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mutlu Deger More articles by this author Mubariz Aydamirov More articles by this author Nebil Akdogan More articles by this author Ismail Onder Yilmaz More articles by this author Seyda Erdogan More articles by this author Yildirim Bayazit More articles by this author Volkan Izol More articles by this author Expand All Advertisement PDF downloadLoading ...