Utilizing the light gas gun system, impact tests on sandwich glass specimens with various structural configurations were performed at high-speed, medium-speed, and low-speed to evaluate the impact resistance of polyvinyl butyral (PVB) sandwich glass. An impact damage test method that incorporates stress data and three-dimensional fracture data was proposed in conjunction with the CT scan-3D reconstruction technique. The experimental findings demonstrated that as glass thickness grew, sandwich glass’ rigidity increased noticeably, and impact resistance of sandwich glass was significantly improved. On the other hand, under the action of elastic deformation energy absorption and horizontal cohesion of the PVB interlayer, the thicker interlayer could consume and disperse more impact energy, making the veins radially distributed and reducing the flying of debris. The conclusion that thin glass-thick interlayer could equivalently replace thick glass-thin interlayer to a certain extent was obtained. The study offers crucial technological backing for sandwich glass’s industrial applicability.