Window Of Opportunity Research Articles

INDONESIA'S FOREIGN POLICY CHANGE TOWARDS ROHINGYA ETHNIC ASYLUM SEEKERS IN 2015: A Foreign Policy Change Perspective

In 2015, Indonesia was shocked by the landing of a foreign ship containing Rohingya refugees in Aceh province. Not only Indonesia, Malaysia and Thailand also experienced the same incident. The refugees came to obtain temporary asylum due to the country's conflict, which threatened the survival of the Rohingya tribe in Myanmar. Indonesia's rejection gave rise to various reactions from within and outside the country. Responding to this, Indonesia finally accepted the existence of Rohingya refugees by also signing the Joint Statement Ministerial Meeting on Irregular Movement of People in Southeast Asia. These foreign policy changes will be examined further using the Foreign Policy Change theory to determine the factors influencing foreign policy-makers in deciding their foreign policy. This research will use explanatory-qualitative methods to analyze Indonesia's momentum in taking windows of opportunity toward the Joint Statement Ministerial Meeting on Irregular Movement of People in Southeast Asia.

City health development planning – experiences from the Hungarian members of the WHO European Healthy Cities Network

ABSTRACT This study showcases the City Health Development Planning (CHDP) methodology developed and implemented in Hungarian designated cities of the World Health Organization European Healthy Cities Network. This methodology is based on those principles that the WHO-EHCN recommends for CHDP works. The methodology consists of two phases: creating a City Health Profile (CHP) with specific components such as content analysis of the city’s strategic policy documents, semi-structured interviews with local political decision-makers, adopting a decentralized and participatory planning approach, and gathering available health-related data from the city. Then, the City Health Development Plan is created based on the statement of the CHP using the CHDP. The effectiveness of CHDP efforts, relies on three crucial factors: local politicians’ commitment, the operation of a local multisectoral steering committee, and annual action plans approved by the local government. Kingdon’s multiple streams theory suggests that issues are addressed when the streams of problems, policy, and politics align. The CHDP methodology described in this paper can effectively support the alignment of the three streams and open a window of opportunity to contribute to creating a healthy urban environment, as demonstrated by the experiences of the Hungarian designated cities of the WHO-EHCN.

Hypothalamic vasopressin sex differentiation is observed by embryonic day 15 in mice and is disrupted by the xenoestrogen bisphenol A

Arginine vasopressin (AVP) neurons of the hypothalamic paraventricular region (AVPPVN) mediate sex-biased social behaviors across most species, including mammals. In mice, neural sex differences are thought to be established during a critical window around birth ( embryonic (E) day 18 to postnatal (P) day 2) whereby circulating testosterone from the fetal testis is converted to estrogen in sex-dimorphic brain regions. Here, we found that AVPPVN neurons are sexually dimorphic by E15.5, prior to this critical window, and that gestational bisphenol A (BPA) exposure permanently masculinized female AVPPVN neuronal numbers, projections, and electrophysiological properties, causing them to display male-like phenotypes into adulthood. Moreover, we showed that nearly twice as many neurons that became AVP+ by P0 were born at E11 in males and BPA-exposed females compared to control females, suggesting that AVPPVN neuronal masculinization occurs between E11 and P0. We further narrowed this sensitive period to around the timing of neurogenesis by demonstrating that exogenous estrogen exposure from E14.5 to E15.5 masculinized female AVPPVN neuronal numbers, whereas a pan-estrogen receptor antagonist exposed from E13.5 to E15.5 blocked masculinization of males. Finally, we showed that restricting BPA exposure to E7.5-E15.5 caused adult females to display increased social dominance over control females, consistent with an acquisition of male-like behaviors. Our study reveals an E11.5 to E15.5 window of estrogen sensitivity impacting AVPPVN sex differentiation, which is impacted by prenatal BPA exposure.

Bioeconomics of juvenile seahorse (Hippocampus erectus) culture: Optimal harvest time

AbstractThe culture of seahorses Hippocampus erectus in captivity represents a window of opportunity for the diversification of the aquaculture activity in the ornamental industry. In this study, we have constructed a bioeconomic model to evaluate the optimal harvest time (OHT) over a culture period of 562 days. The bioeconomic model was integrated with three submodels: biological, technological, and economic. Three different mortality rates were used for different periods in culture, registering a higher survival in the period from 0 to 60 days with a rate of 53.4%. The sensitivity analysis showed that the mortality rate in this period was the parameter with the greatest influence on the benefits. The Von Bertalanffy growth model was indicated to describe the growth of H. erectus given its statistical significance using Theil's inequality coefficient, registering parameters of (L∞ = 141.62 mm) and (k = 0.0049 month‐1). The bioeconomic model determined the OHT in the 4th month of culture, the time when the maximum profit is recorded. It is concluded that the culture presents challenges to be addressed although the bioeconomic model allows for demonstrating the OHT.

A combined intervention strategy to increase linkage to and retention in substance use treatment for individuals accessing hospital-based services: study protocol

BackgroundIn 2020, New Mexico had the highest alcohol related death and the 11th highest drug overdose rate in the U.S. Towards the long-term goal of addressing this public health problem, we are implementing and evaluating an multi-level intervention designed to identify adults at risk of substance use disorder (SUD) and encourage linkage to and retention in treatment. The first level includes equipping the ED and medical inpatient units of a safety-net hospital with a method to screen individuals at risk of a SUD. The second level includes Seeking Safety (SS), a trauma-specific treatment for PTSD and SUD; and pharmacotherapy for SUD. Motivational Interviewing (MI) is used throughout both levels. Using the SPIRIT guidelines and checklist, this study protocol describes the multi-level intervention and the methodology we are using to assess feasibility and effectiveness.MethodsWe are using a Type 1 hybrid implementation design with a non-randomized approach (ISRCTN registration # ISRCTN33100750). We aim to enroll 110 adults (≧18) who screen positive for unhealthy use of alcohol, prescription medications (used nonmedically) and/or illicit drugs. Peer support workers are responsible for screening, using MI to increase engagement in screening and treatment and delivery of SS. Pharmacotherapy is provided by addiction clinical specialists. Treatment is provided post hospital discharge via telehealth to increase access to care. Participants are identified through (1) review of electronic health records for individuals with a chief or secondary complaint or mental health condition relating to alcohol and/or other drug use, (2) referrals from clinical staff and (3) screening in the ED and medical inpatient units. Feasibility is being measured through process data. Effectiveness will be determined by changes in two primary outcomes: (i) PTSD symptom severity; and (ii) substance use.DiscussionOur study will expand on research related to the implementation of treatment strategies for patients presenting at EDs and admitted to medical inpatients units wherein there is a significant window of opportunity to link patients with follow-up behavioral and clinical services for alcohol and/or drug misuse. The challenges associated with implementation and strategies that have been helpful to address these challenges will further inform the field.

Identifying a therapeutic window of opportunity for people living with primary sclerosing cholangitis: Embryology and the overlap of inflammatory bowel disease with immune mediated liver injury.

Primary sclerosing cholangitis (PSC) is a variably progressive, fibrosis-causing autoimmune disorder of the intra- and extra-hepatic bile ducts of unclear etiology. PSC is commonly (in 60-90% of cases) associated with an inflammatory bowel disease (IBD) like PSC-IBD, and less commonly with an autoimmune hepatitis (AIH) like PSC-AIH or AIH-overlap disorder. Hepatologists and Gastroenterologists often consider these combined conditions as distinctly different from the classical forms in isolation. Here, we review recent epidemiologic observations and highlight that PSC-IBD and PSC-AIH overlap appear to represent aspects of a common PSC clinico-pathological pathway and manifest in an age-of-presentation dependent manner. Particularly from the pediatric experience, we hypothesize that all cases of PSC likely originate from a complex "Early PSC"-"IBD"-"AIH" overlap in which PSC defines the uniquely and variably associated "AIH" and "IBD" components along an individualized lifetime continuum. We speculate that a distinctly unique, 'diverticular autoimmunity' against the embryonic cecal- and hepatic diverticulum derived tissues may be the origin of this combined syndrome, where "AIH" and "IBD" variably commence then variably fade while PSC progresses with age. Our hypothesis provides an explanation for the age-dependent variation in the presentation and progression of PSC. This is critical for the optimal targeting of studies into PSC etiopathogenesis and emphasizes the concept of a "developmental window of opportunity for therapeutic mitigation" in what is currently recognized as an irreversible disease process. The discovery of such a window would be critically important for the targeting of interventions, both administration of current therapies and therapeutic trial planning.

How sociology can help us save ourselves

AbstractThis article is derived from my 2024 ESS presidential address. I discuss my new book and how a sociological lens helps us to understand the process through which we can save ourselves from the climate crisis. After explaining why the state and the market have struggled to implement sufficient policies to address the climate crisis, I present the AnthroShift as a theory that explains how social actors reorient after risk pivots to open windows of opportunity for social change. I discuss why civil society is most likely to mobilize after there is a generalized sense of climate risk and summarize how climate activists are currently engaging in non‐violent civil disobedience as a first step in an expanded civil society sector that is likely to put pressure on the state and the market to help us save ourselves. I conclude by presenting three steps that can be taken to help us save ourselves from the climate crisis.

Early and late onset childhood eczema: Role of preconceptional, pre-natal and post-natal environmental exposures

BackgroundDespite mounting evidence linking indoor and outdoor environments to eczema, the role of indoor and outdoor environmental pollutant(s) exposure during critical time window(s) on eczema remains unknown. ObjectiveTo investigate the correlations between childhood eczema and itchy rashes and exposure to outdoor air pollution and the home environment. MethodsA combined cross-sectional and retrospective cohort study of 8689 kindergarten students was conducted. We collected information about each child's health outcomes and home environment, as well as calculated individual exposure to air pollutants. Multiple logistic regression models were used to investigate the links between indoor and outdoor environments and childhood eczema and itchy rashes. ResultsChildhood ever doctor-diagnosed eczema (DDE) was linked to NO2, CO, PM2.5, PM2.5-10 and PM10 exposure during the preconceptional, pregnant, and postnatal periods, with ORs (95 % CI) ranging from 1.06 (1.00–1.13) to 1.21 (1.08–1.37). Ever doctor-diagnosed itchy rash (DDIR) was associated with SO2, CO, PM2.5, PM2.5-10 and PM10 exposure during preconceptional and postnatal periods, with ORs (95 % CI) ranging from 1.11 (1.02–1.20) to 1.31 (1.13–1.52). Preconceptional outdoor air pollution was associated with a higher risk of ever, early, and late DDE and DDIR. Indoor smoke, renovation, and dampness were all associated with DDE and DDIR. Postnatal exposure to plants has been linked to both ever and early DDE. There was no link between indoor environments and late DDE. Furthermore, pregnancy has been identified as a critical indoor exposure time window for DDE and DDIR. ConclusionsEarly-life exposure to outdoor air pollutants and indoor environments, particularly before birth, played important roles in childhood eczema.

Trends and Triggers: Analyzing the Co-Movement of Cryptocurrency and NFT Prices

This paper aims to explore the complex interrelationships between the prices of cryptocurrency, specifically Ethereum (ETH), and five top Non-Fungible Token (NFT) collections: Bored Ape Yacht Club, Mutant Ape Yacht Club, Azuki, Moonbirds, and Otherdeed. Motivated by the intertwining dynamics of these digital assets and the unexplored nature of their interdependencies, this study employs a Vector Autoregressive (VAR) model and utilizes Granger Causality to dissect the multifaceted interactions. The analysis period ranges from April 2021 to January 2023, a critical window of exponential growth and fluctuation in the digital asset market. The results demonstrate a statistically significant impact of ETH prices on NFT collection prices, but not vice versa, revealing the strong dependence of the NFT market on cryptocurrency volatility. Specifically, the research finds that changes in ETHs value are predictive of shifts in NFT prices, whereas NFT price fluctuations lack predictive power for ETH prices. In conclusion, this research represents an advancement in understanding price dynamics in the rapidly evolving digital economy. By innovatively analyzing the co-movement of cryptocurrencies and NFTs, it not only enriches existing knowledge but also paves the way for further exploration, offering practical insights for diverse stakeholders navigating this exciting, ever-changing field.

A nasal chemosensation–dependent critical window for somatosensory development

Nasal chemosensation is considered the evolutionarily oldest mammalian sense and, together with somatosensation, is crucial for neonatal well-being before auditory and visual pathways start engaging the brain. Using anatomical and functional approaches in mice, we reveal that odor-driven activity propagates to a large part of the cortex during the first postnatal week and enhances whisker-evoked activation of primary whisker somatosensory cortex (wS1). This effect disappears in adult animals, in line with the loss of excitatory connectivity from olfactory cortex to wS1. By performing neonatal odor deprivation, followed by electrophysiological and behavioral work in adult animals, we identify a key transient regulation of nasal chemosensory information necessary for the development of wS1 sensory-driven dynamics and somatosensation. Our work uncovers a cross-modal critical window for nasal chemosensation–dependent somatosensory functional maturation.

V-A ECMO window of opportunity: identification of potential responders after an acute myocardial infarction complicated by cardiogenic shock

Abstract Funding Acknowledgements None. Background V-A ECMO is designed to supply oxygen demands in patients with circulatory failure. Neutral results obtained in recent cardiogenic shock (CS) trials are probably related to the inclusion of a high proportion of patients with SCAI C stage, in many of whom, the device might not provide hemodynamic benefit despite the addition of inherent complications. Mechanical circulatory support could potentially have a role only for patients in SCAI D-E stages. Purpose Our aim was to explore the excess in mortality explained by a SCAI D-E stage at 12h, compared to a SCAI A-C stages at 12h, in patients admitted due to an acute myocardial infarction (AMI) complicated by CS (stages C-E at admission). Additionally, we aimed to identify those factors at admission—clinical, electrocardiographic, gasometrical, echocardiographic, and angiographic—which predict whether a patient will progress to SCAI D-E stages within the subsequent 12h from CS onset. Main Outcome: SCAI D and E stage at 12h. Methods We retrospectively analysed those patients admitted due to an AMI in SCAI C-E stages at admission, that had been prospectively screened for EUROSHOCK trial. We classified the patients in two groups: "SCAI A-C" and "SCAI D-E" at 12 hours and conducted a survival analysis. Additionally, we conducted a univariate and multivariate analysis including arrival potential predictors for SCAI D-E at 12 hours. Results A total of 72 patients were included. At admission 25 patien were in SCAI D-E. At 12 hours, 42 patients were in SCAI D-E, and this group showed a higher 30-day mortality rate particularly explained by an excess of mortality within the first 7 days (Figure 1). There were no significant differences between groups in most baseline characteristics (Table 1) such as age or gender. We observed a fewer proportion of previous chronic treatment with negative inotropes (betablockers and calcium channel antagonists) in the SCAI D-E group. Overall, anterior ST elevation on EKG was more prevalent among SCAI D-E group, median pH lower and median glycaemia and lactate higher. In the multivariate analysis after adjustment by confounders, the independently predictors at arrival for the development of a SCAI D-E stage at 12h were culprit LAD, cardiac arrest in the cath Lab, low initial median pH and final TIMI <3 result. Conclusions In a cohort of AMI patients complicated by CS, those patients who remained in a SCAI D-E stage at 12 hours from CS onset, compared to those in A-C, showed a 26% excess mortality at 30-day follow-up, especially during the first week. Patients who presented with LAD as the culprit artery, low initial pH, cardiac arrest in the cath lab, and got a TIMI <3 result after PCI were independently associated with the development of SCAI D-E within 12 hours from admission. Patients meeting these criteria could benefit from early selective mechanical support and be taken into consideration in the design of future randomized controlled trials.

Development of Titanium Production in Ukraine: Evolving Prospects Based on National R&D

Introduction. The development of Ukraine’s resource potential in the field of mining and advanced processing of titanium raw materials is one of the important components of countering military threats and the national economy recovering based on new technologies.Problem Statement. The realities of wartime reinforce the importance of domestic resource involvement to resumption of the titanium products complete production cycle in Ukraine, which can facilitate integration into global value chains.Purpose. To determine the directions of titanium production development in Ukraine based on the available resource and production potential, foreign and domestic R&D.Materials and Methods. The authors have used data of statistical observations of the State Statistics Service in Ukraine, the U.S. State Geological Survey, the World Intellectual Property Organization; methods of systematic approach, economic and statistical, calculation and design, graph analytical methods, statistical comparisons and grouping, systematic and comparative analysis.Results. The possibilities of realizing resource, production, and R&D potential for deep processing of titanium metal in Ukraine have been substantiated. The directions of the Ukrainian titanium industry development have been offered. The construction of new and/or modernization of production facilities for processing Ukrainian titanium raw materials based on domestic scientific developments has been substantiated.Conclusions. Ukraine has a strategic potential to create a full cycle of titanium products production. Providing favorable conditions for attracting investment and access to capital and financial and economic instruments facilitates technological modernization. This, in turn, will help open “a window of opportunities” for Ukraine for manufacturing titanium products with high added value for the needs of the military industrial complex and other high-tech industries.

The electric vehicle sector in Brazil, India, and South Africa: Are there green windows of opportunity?

Abstract The shift to electric mobility is driving disruptive transformations in the automotive sector worldwide. It poses significant but different opportunities and challenges to incumbents and latecomers at both the firm and country levels. China’s green industrial policy has facilitated its rapid catching up and even leapfrogging in some domains of electromobility. This article asks whether the exploitation of this window of opportunity can be replicated in other latecomer countries. Accordingly, it provides a comparative analysis of the automotive green window of opportunity in Brazil, India, and South Africa, three emerging economies with long established but structurally different automotive industries. To do so, it examines domestic preconditions, policy and enterprise responses, and preliminary industrial development outcomes. Although all the three countries face constraints in replicating China’s relative success, the article shows how green opportunities and threats are unequally divided between the three countries.

Factors influencing subseasonal predictability of northern Eurasian cold spells

AbstractCold‐air outbreaks have significant impacts on human health, energy consumption, agriculture, and overall well‐being. This study aims to evaluate the effectiveness of Subseasonal‐to‐Seasonal (S2S) models in predicting cold conditions over northern Eurasia, defined here as the lower tercile of weekly mean 2‐metre temperature anomalies. To assess the predictability of these events we use ensemble hindcasts from five prediction systems from the S2S database. Our analysis focuses on identifying the conditions under which the models confidently predict cold temperatures with a high (>0.5) probability 3–4 weeks ahead, which potentially can represent windows of forecast opportunity. We compare the group of forecasts that correctly predicted the events to the group that forecasted events that did not occur in practice (false alarms). Most of the confident forecasts of cold spells, both correct and false alarms, have cold anomalies already in the initial conditions, often in conjunction with either a negative phase of the North Atlantic Oscillation, or Scandinavian Blocking. We find that S2S models tend to overpredict cold temperatures, with false alarms occurring more likely when the forecasts are initialized during a weak polar vortex. Furthermore, most of the confident false alarms receive the signal from the stratosphere rather than following internal tropospheric dynamics. False alarms initialized during the weak polar vortex conditions are more common when the vortex is in a recovery stage and, subsequently, the downward ‐propagating signal is short‐lived in the troposphere. The analysis of forecasts during different Madden–Julian Oscillation (MJO) phases shows that nearly half of all confident correct cold‐temperature forecasts are initialized during an active MJO in phases 6–8. On the other hand, most false alarms occur during phase 3, which we suggest is due to the presence of the Scandinavian Blocking regime in the initial conditions for this phase.

Window of OCMO Opportunity: the Communication Competency Index for Media Teams in Nuclear Cities

The issue of evaluating the effectiveness of communications and PR has long been a staple topic of debate among industry specialists. In late 2023, driven by the initiative of the Rosatom State Corporation and within the framework of a media project accelerator, an effort was made to synthesize various approaches for assessing the performance of media teams. This effort resulted in the creation of the Communication Competency Index for media teams in nuclear cities. The creators of the index discuss its development process, the criteria it encompasses, and its potential applications.

Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors.

Genetic variations in proteins of the mechanistic target of rapamycin (mTOR) pathway cause a spectrum of neurodevelopmental disorders often associated with brain malformations and with intractable epilepsy. The mTORopathies are characterized by hyperactive mTOR pathway and comprise tuberous sclerosis complex (TSC) and focal cortical dysplasia (FCD) type II. How hyperactive mTOR translates into abnormal neuronal activity and hypersynchronous network remains to be better understood. Previously, the role of upregulated GluN2C-containing glutamate-gated N-methyl-D-aspartate receptors (NMDARs) has been demonstrated for germline defects in the TSC genes. Here, we questioned whether this mechanism would expand to other mTORopathies in the different context of a somatic genetic variation of the MTOR protein recurrently found in FCD type II. We used a rat model of FCD created by in utero electroporation of neural progenitors of dorsal telencephalon with expression vectors encoding either the wild-type or the pathogenic MTOR variant (p.S2215F). In this mosaic configuration, patch-clamp whole-cell recordings of the electroporated, spiny stellate neurons and extracellular recordings of the electroporated areas were performed in neocortical slices. Selective inhibitors were used to target mTOR activity and GluN2C-mediated currents. Neurons expressing the mutant protein displayed an excessive activation of GluN2C NMDAR-mediated spontaneous excitatory postsynaptic currents. GluN2C-dependent increase in spontaneous spiking activity was detected in the area of electroporated neurons in the mutant condition and was restricted to a critical time window between postnatal days P9 and P20. Somatic MTOR pathogenic variant recurrently found in FCD type II resulted in overactivation of GluN2C-mediated neuronal NMDARs in neocortices of rat pups. The related and time-restricted local hyperexcitability was sensitive to subunit GluN2C-specific blockade. Our study suggests that GluN2C-related pathomechanisms might be shared in common by mTOR-related brain disorders.

Children's food allergy: Effects of environmental influences and antibiotic use across critical developmental windows

BackgroundIncreasing studies linked outdoor air pollution (OAP), indoor environmental factors (IEFs), and antibiotics use (AU) with the first wave of allergies (i.e., asthma, allergic rhinitis, and eczema), yet the role of their exposures on children’s second wave of allergy (i.e., food allergy) are unknown. ObjectivesTo investigate the association between exposure to OAP and IEFs and childhood doctor-diagnosed food allergy (DFA) during the pre-pregnancy, prenatal, early postnatal, and current periods, and to further explore the effect of OAP and IEFs on DFA in children co-exposed to antibiotics. MethodsA retrospective cohort study involving 8689 preschoolers was carried out in Changsha, China. Data on the health outcomes, antibiotic use, and home environment of each child were collected through a questionnaire. Temperature and air pollutants data were obtained from 8 and 10 monitoring stations in Changsha, respectively. Exposure levels to temperature and air pollutants at individual home addresses were calculated by the inverse distance weighted (IDW) method. Multiple logistic regression models were employed to assess the associations of childhood DFA with exposure to OAP, IEF, and AU. ResultsChildhood ever doctor-diagnosed food allergy (DFA) was linked to postnatal PM10 exposure with OR (95% CI) of 1.18 (1.03–1.36), especially for CO and O3 exposure during the first year with ORs (95% CI) = 1.08 (1.00–1.16) and 1.07 (1.00–1.14), as well as SO2 exposure during the previous year with OR (95% CI) of 1.13 (1.02–1.25). The role of postnatal air pollution is more important for the risk of egg, milk and other food allergies. Renovation-related IAP (new furniture) and dampness-related indoor allergens exposures throughout all time windows significantly increased the risk of childhood DFA, with ORs ranging from 1.23 (1.03–1.46) to 1.54 (1.29–1.83). Furthermore, smoke-related IAP (environmental tobacco smoke [ETS], parental and grandparental smoking) exposure during pregnancy, first year, and previous year was related to DFA. Additionally, exposure to pet-related indoor allergens (cats) during first year and total plant-related allergens (particularly nonflowering plants) during previous year were associated with DFA. Moreover, exposure to plant-related allergy during first and previous year was specifically associated with milk allergy, while keeping cats during first year increased the risk of fruits/vegetables allergy. Life-time and early-life AU was associated with the increased risk of childhood DFA with ORs (95% CI) = 1.57 (1.32–1.87) and 1.46 (1.27–1.67), including different types food allergies except fruit/vegetable allergy. ConclusionsPostnatal OAP, life-time and early-life IEFs and AU exposure played a vital role in the development of DFA, supporting the "fetal origin of childhood FA" hypothesis.

Exploring Digital Entrepreneurship and the Development of Entrepreneurial Skills in General Studies Students

In a changing and complex world, the university is no stranger to the incursion of the digital world and the development of entrepreneurial skills in the learning of young university students. Currently, digital ventures have emerged and many of them are seen as tools and spaces for the development of entrepreneurial skills such as leadership, creativity and even new forms of teamwork. The development of skills that lead to the creation of different ventures is a window of opportunity to achieve personal and social improvement. This research was developed under the qualitative approach, and, from the methodology of grounded theory, the experiences of general studies students and their entrepreneurial skills were analyzed using digital resources developed from their curricular experiences. Thus, through semi-structured interviews and content analysis, it was possible to know how these entrepreneurial skills were able to develop learning based on creativity, leadership and teamwork. Ten general studies university students selected under inclusion criteria participated. The technique used was in-depth interview, description and categorical analysis. The results show that the students' experience reflects a partial knowledge of what is meant by digital entrepreneurship. Likewise, it is concluded that the learning experiences of general studies students about their entrepreneurial skills are very important in vocational training. Finally, it is hoped that this research can lead to new studies on the impact that digital entrepreneurship has on society and the culture of our young university students. Received: 5 November 2023 / Accepted: 13 March 2024 / Published: 5 May 2024

Officer Perceptions of Mandatory Annual Physical Fitness Standards

One of the most important topics regarding law enforcement is officer fitness, or the larger concern, a lack thereof. Lack of fitness can be correlated to instances of inappropriate use of force and the public outcry of police brutality. Physical conditioning can directly assist an officer in achieving their main objective of every shift which is to go home healthy and safe. Increased fitness increases confidence and provides officers with a greater window of opportunity to de-escalate, showing the public that less drastic measures may be taken in handling stressful confrontations. Failure to set or maintain standards of fitness has in some cases, opened the door to civil litigation such as in Parker v District of Columbia where the proceedings showed that the District of Columbia was deliberately indifferent to physical standards resulting in significant financial compensation. Agencies should consider that an officer’s shift and work environment may indirectly lead to a lack of attention to health and fitness. A “complacency kills” approach may be able to outline the dangers of these lapses in standards but if a pathway cannot be created for these officers, then it may only reinforce the negative thought that they may not go home.

Climate Change and Mental Health (A Global Analysis)

Climate change and its corresponding consequences have been recognized as one of the dominating issues of global concern. Many governments of various nations are currently making efforts to mitigate the undesirable consequences of climate change. The essay is focused on carrying out an analysis of the effect of climate change on mental health in the United Kingdom. The paper presented a methodological framework for the diverse and multiple channels by which climate change impacts on a person’s mental health. In connection with this, this methodological analysis led to the conceptualization of the variables that link or mediate the effect of climate change on human mental health and corresponding well-being. There was an exploration of evidence-based analysis of climate change modifies the variables that impact mental health; this will take care of the expression of the diverse pathways of effect. The essay recognizes that despite the mental health dangers and risks associated with climate change, adopting a strategic climate action can also be a window of opportunity to harness its impact and engage in proactive and preventable measures.