Rapid urbanization entails complex problems not only in cities, but also within urban agglomerations. In modern landscape science, the greatest problems are primarily related to the ecological state of urban ecosystems. In this context, the most important task of urbanism is the interdisciplinary study of urban infrastructure in relation to the well-being of inhabitants, with a focus on the sustainable development of urban agglomerations. The aim of this study is to conduct a theoretical analysis of interdisciplinary research on the interactions between humans and the urban environment in the context of intensive urbanization, as well as to be an empirical study of the relationship between the real ecological state of the city of Astana, based on the use of geographical, environmental, cartographic, statistical, sociological, and socio-psychological research methods, aimed at identifying the mental well-being of citizens in correlation with their consumed urban ecosystem services using an associative psychological experiment, socio-psychological survey, and GIS mapping. As a result of this study, the authors have determined that the research hypothesis 1 “Spatial representations of the city’s geoecological state are interrelated with the mental well-being and satisfaction with urban ecosystem services of citizens depending on the area of residence” is confirmed. Additionally, a positive correlation has been noted among the key indicators and criteria of geoecological condition, mental well-being, and satisfaction with urban ecosystem services across different districts of the city.
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