The objectives of this study were to look into the situation of DNA analysis in the country in terms of its application in solving and preventing crimes and to identify the problems encountered and best practices of PNP DNA Laboratory Division. After knowing the situation, problems encountered, and best practices the researcher proposed an action plan in order to try and contribute to the effectiveness and efficiency of the division. 
 This study used qualitative-case study approach through thematic analysis. Two (2) participants were chosen as participants from PNP- Regional Forensic Unit COR. The study utilized the interview as the data gathering tool. The interview was done through face-to-face meeting. The main themes that came about in this study about the problems they encountered are: backlogs of cases; lack of reagent for testing; insufficient equipment and facilities in DNA laboratories; and unfamiliar recognition/evaluation and collection of field investigators to DNA evidence. The main themes that came about in this study about their best practices are: case prioritization; peer tutoring and supervision; diligent care for the equipment; and open communication to the stakeholders. 
 Based on the findings of the study, the researcher arrived at the following conclusions: 1. The DNA Analysis in PNP-Regional Forensic Unit-Cordillera cannot facilitate the testing and analysis of DNA specimen submitted as evidence due to lack of equipment. 2. Due to the increasing demands for scientific-based investigation using DNA profiles the need for additional DNA analysts and supplemental reagents increases. Because of the surge of demands, problems in the supply of reagents used for testing and analysis of DNA is prevalent. This insufficient supply of reagents leads to burdensome piling of cases. 3. The case prioritization is because of the overzealous evidence collection during the conduct of crime scene processing, in which giving priority to the processing of specimens of DNA reference standards for cases that are expected to have a definitive result may reduce the wastage of reagents and resources which will greatly contribute to the purpose for which DNA testing is intended.