Cracks in asphalt mixtures compromise the structural integrity of roads, increase maintenance costs, and shorten pavement lifespan. These cracks allow for water infiltration, accelerating pavement deterioration and jeopardizing vehicle safety. This research aims to evaluate the impact of synthetic fibers, specifically glass fiber (GF) and polypropylene fiber (PPF), on the crack resistance of Hot-Mix Asphalt (HMA). An optimal asphalt binder content of 5% was used in all sample designs. Using the dry mixing technique, GFs and PPFs were incorporated into the HMA at dosages of 0.50%, 1.00%, and 1.50% by weight of the aggregate. The effects of these fibers on the mechanical fracture properties of the HMA were assessed using Semi-Circular Bending (SCB), Indirect Tensile Asphalt Cracking Tests (IDEAL-CTs), and Three-Point Bending (3-PB) tests. This study focused on fracture parameters such as fracture work, peak load, fracture energy, and crack indices, including the Flexibility Index (FI) and Crack Resistance Index (CRI). The results from the SCB and IDEAL-CT tests showed that increasing GF content from 0.5% to 1.5% significantly enhances the flexibility and crack resistance of HMA, with FI, CRI, and CT Index values increasing by 247.5%, 55%, and 101.35%, respectively. Conversely, increasing PPF content increases the mixture’s stiffness and reduces its crack resistance. The PP-1 mixture exhibited higher FI and CT Index values, with increases of 31.1% and 10%, respectively, compared to the PP-0.5 mixture, based on SCB and IDEAL-CT test results. The SCB, IDEAL-CT, and 3-PB test results concluded that fibers significantly influence the fracture properties of bituminous mixtures, with a 1% reinforcement dosage of both PPFs and GFs being optimal for enhancing performance across various applications.