Sire Of Cow Research Articles

Perspectives for the use of genomic selection for genetic improvement of dairy cattle in Ukraine

An important problem in modern dairy cattle breeding is the achievement of a high level of genetic progress in economically important traits through the implementation of effective breeding programs. For this purpose, genomic selection is currently used in many countries of the world. The aim of the study was to investigate possibilities of use of genomic selection in dairy cattle breeding in Ukraine. On the basis of analysis of “Catalogue of sires of dairy and dual-purpose breeds for reproduction of cows in 2020” (sperm of these sires was used in Ukraine) two methods of breeding value estimation were compared: 1) traditional method based on pedigree and performance of progeny; 2) genomic method based on effects of SNPs. Considerable advantage of sires with genomic evaluations was proved. These sires excel sires with traditional evaluation for milk yield by 1.6 times, for fat percentage by 2.2 times, for fat yield by 1.7 times, for protein percentage by 2.1 times and for protein yield by 1.7 times. Using estimates of breeding values of sires pare-wise genetic correlations between main genetic traits were computed. The negative genetic relationship between milk yield and fat and protein percentages was revealed. Values of energy corrected milk (ECM) of daughters and dams of sires across breeds and countries of origin were calculated. It was shown that dams of sires of Holstein and Jersey breeds had highest values of energy corrected milk (9,132.0 kg and 8,041 kg, respectively) while dams of sires of Ukrainian Black-and-White dairy breed had lowest values of this trait (5,848.1 kg). According to country-of-origin daughters of sire’s form USA, Canada and the Netherlands had highest values of energy corrected milk. Values of response to selection using traditional breeding program and genomic selection were compared. It was proved that by means of shortening generation intervals on pathways of genetic improvement “sires of bulls”, “sires of cows” and “dams of bulls” using genomic selection it is possible to increase rate of genetic progress for milk yield from 100.1 kg to 180.0 kg that is by 80%

Herd life, lifetime production, and profitability of Viking Red-sired and Montbéliarde-sired crossbred cows compared with their Holstein herdmates

The first 2 generations from a 3-breed rotation of the Viking Red (VR), Montbéliarde (MO), and Holstein (HO) breeds were compared with their HO herdmates in high-performance commercial herds in Minnesota. The designed study enrolled pure HO females in 2008 to initiate a comparison of 3-breed rotational crossbreds with their HO herdmates. Sires of cows were proven artificial insemination bulls selected for high genetic merit in each of the 3 breeds. The first-generation cows calved for a first time from 2010 to 2014 and had 376 VR × HO and 358 MO × HO crossbreds to compare with their 640 HO herdmates. The second-generation cows calved for a first time from 2012 to 2014 and had 109 VR × MO/HO and 117 MO × VR/HO crossbreds to compare with their 250 HO herdmates. Collection of data ceased on December 31, 2017, and all cows studied had the opportunity for 45 mo in the herd after first calving. Production of milk, fat, and protein (kg) during lifetimes of cows was estimated from test-day observations with best prediction. The lifetime profit function included revenue and cost. Revenue was from production, calves, and slaughter of cull cows. Costs included feed cost during lactation, lactating overhead cost, dry cow cost (including feed cost during dry periods), replacement cost, health treatment cost, insemination cost, fertility hormone cost, pregnancy diagnosis cost, hoof trimming cost, and carcass disposal cost. For individual cows with herd life longer than 45 mo after first calving, survival of cows was projected beyond 45 mo after first calving to estimate herd life, production, and profitability. The 2-breed crossbreds had +158 d longer herd life and the 3-breed crossbreds had +147 d longer herd life compared with their respective HO herdmates. Also, 12.4% of the 2-breed crossbreds died up to 45 mo after first calving compared with 16.3% of their HO herdmates. Furthermore, approximately 29% of both the 2-breed and 3-breed crossbreds lived beyond 45 mo after first calving compared with approximately 18% of their respective HO herdmates. On a lifetime basis, the 2-breed and 3-breed crossbreds provided +$122 and +$134, respectively, more cull cow revenue compared with their HO herdmates. For lifetime replacement cost, the 2-breed crossbreds did not differ from their HO herdmates; however, the 3-breed crossbreds had -$28 less lifetime replacement cost compared with their HO herdmates because of their younger age at first calving. The combined 2-breed crossbreds had +$0.473 (+13%) more daily profit (ignoring potential differences for feed efficiency) and the combined 3-breed crossbreds had +$0.342 (+9%) more daily profit compared with their respective HO herdmates. This resulted in +$173 more profit/cow annually for the combined 2-breed crossbreds and +$125 more profit/cow annually for the combined 3-breed crossbreds compared with their respective HO herdmates.

Fertility and 305-day production of Viking Red-, Montbéliarde-, and Holstein-sired crossbred cows compared with Holstein cows during their first 3 lactations in Minnesota dairy herds

Three generations of crossbred cows from a 3-breed rotation of the Viking Red (VR), Montbéliarde (MO), and Holstein (HO) breeds were compared with HO herdmates in 7 high-performance, commercial dairy herds in Minnesota. The designed study was initiated in 2008 with the enrollment of 3,550 HO females. Sires of cows were proven artificial insemination bulls and were high-ranking for genetic merit within each of the VR, MO, and HO breeds. The first generation of cows calved a first time from 2010 to 2017 and consisted of 644 VR × HO and 616 MO × HO 2-breed crossbreds and their 1,405 HO herdmates. The second generation calved a first time from 2012 to 2017 and consisted of 615 VR × MO/HO and 568 MO × VR/HO crossbreds and their 1,462 HO herdmates. The third generation calved a first time from 2014 to 2017 and was composed of 466 HO × VR/MO/HO and HO × MO/VR/HO crossbreds combined and their 736 HO herdmates. Collection of data ceased on December 31, 2017, and for the duration of study, many of the 2-breed and 3-breed crossbreds and their HO herdmates had the opportunity to complete at least 3 lactations, whereas the HO-sired crossbreds and their HO herdmates had the opportunity to complete 1 lactation. The 305-d actual (not mature equivalent) production of milk, fat, and protein was estimated from test-day observations with best prediction and cows with <305 DIM were projected to 305 d. The 2-breed and 3-breed crossbred cows had superiority over their HO herdmates for all of the fertility traits measured. The 2-breed crossbreds had -9, -17, and -15 d fewer days open than their HO herdmates during first, second, and third lactation, respectively. Also, the 3-breed crossbreds had -15, -19, and -20 d fewer days open than their HO herdmates during first, second, and third lactation, respectively. Cows in these herds had young ages at first calving of 22 to 23 mo across the breed groups, and the 3-breed crossbreds had significantly younger ages at first, second, and third calving than their HO herdmates. The 2-breed crossbreds had +2% higher fat plus protein production (kg) during first lactation, but did not differ during second and third lactation, from their HO herdmates. The 3-breed crossbreds had -3% to -4% lower fat plus protein production (kg) than their HO herdmates in each of their first 3 lactations. During first lactation, the HO-sired crossbreds did not differ for fat plus protein production (kg) from their HO herdmates.

The effect of the country of origin of the sire on milk performance of primiparous Jersey cows

The aim of this study was to determine the effect of the country of origin of the sire on the milk performance of primiparous Jersey cows kept under identical management conditions in Poland. Experimental cows were divided into four groups: daughters of bulls from the USA, Denmark, Canada and Poland. The effect of the paternal group on the milk performance of primiparous cows was estimated. A two-way contingency table was prepared to assess the association between the sire’s country of origin and peak lactation. To present the course of daily milk yield during 305-day lactation, linear graphs were plotted with linear trends depending on the origin of sires of primiparous cows. Daughters of Polish bulls, in comparison to the other genetic groups of primiparous cows, had by the lowest daily milk yields, as well as the lowest concentrations of protein and dry matter in their milk. Primiparous cows sired by bulls from Denmark had the highest daily milk yields and the lowest fat-to-protein ratios in their milk. Analysis of the effect of the origin of the sire on the milk performance of primiparous Jersey cows during 305-day lactation revealed significantly the lowest milk, protein and dry matter yield and the lowest content of protein in the milk for the daughters of Polish bulls. Primiparous cows from this group and the daughters of bulls from the USA had significantly the lowest fat yield and the lowest dry matter content in their milk. Daughters of Polish bulls in comparison to daughters of foreign bulls had a significantly higher concentration of lactose in their milk. The vast majority of primiparous Jersey cows sired by imported bulls reached peak daily milk yields from day 31 to day 60 of lactation. The lactation curve and the first-order trend for daily milk yields were most advantageous in primiparous cows sired by bulls from the USA and Canada. The use of semen from imported Jersey bulls in the Polish population of this cattle breed results in increased milk yields in primiparous cows sired by those bulls, as well as beneficial concentrations of milk constituents. The results of this study indicate that under Polish management conditions the use of semen from Danish bulls is preferable, although further research should be conducted to determine the lifetime productivity of cows and concentrations of milk constituents.

114 The relationship of cell mediated immune response of Brahman cows on calving interval

Abstract The relationships between cell-mediated immune response (CMIR) of cows and calving interval and calf growth were evaluated. Calving interval was evaluated for each of the initial 7 life-time opportunities that females had to produce a calf. The number of days from when the cow had a calf until she calved again determined the cow’s calving interval for each year. The Spring breeding seasons were divided into 45-d artificial insemination and 45-d natural service periods. The Fall breeding season was natural service each year. Multiparous Brahman cows (n = 435) had records for breeding and calving dates and calf weaning weights. The CMIR (hypersensitivity response to Candida albicans measured using tail-fold thickness) was determined once for each female in the Fall and early Winter 2015. Cows were classified into response groups based on mean and SD of CMIR. High responders were those with CMIR ½ SD ≥ the mean (≥ 2.8 mm), Intermediate cows were within ½ SD of the mean (2.7-1.8 mm), and cows ½ SD ≤ the mean were Low (≤ 1.7 mm). Data were analyzed using repeated measures, mixed, and Chi Square procedures (SAS 9.4). Variables included calving interval, cow age, CMIR response group, pregnancy status, calf count, calf sex, cow sire, calf sire, and calf adjusted 180-d weaning weight. A greater proportion of High CMIR cows made it to their 6th calving interval. Chi Square analysis indicated that High CMIR cows were more likely to remain in the herd longer and produce a calf each year. Cows with High CMIR had a greater stayability (P = 0.1). Selection for High CMIR can result in selection of cows which are more likely to remain in the herd long enough to be profitable as they have a greater stayability and shorter calving intervals (about 25 days) than their Low CMIR herdmates.

Test-day or 305-day milk yield for genetic evaluation of Gir cattle

Abstract: The objective of this work was to compare genetic evaluations of milk yield in the Gir breed, in terms of breeding values and their accuracy, using a random regression model applied to test-day records or the traditional model (TM) applied to estimates of 305-day milk yield, as well as to predict genetic trends for parameters of interest. A total of 10,576 first lactations, corresponding to 81,135 test-day (TD) records, were used. Rank correlations between the breeding values (EBVs) predicted with the two models were 0.96. The percentage of animals selected in common was 67 or 82%, respectively, when 1 or 5% of bulls were chosen, according to EBVs from random regression model (RRM) or TM genetic evaluations. Average gains in accuracy of 2.7, 3.0, and 2.6% were observed for all animals, cows with yield record, and bulls (sires of cows with yield record), respectively, when the RRM was used. The mean annual genetic gain for 305-day milk yield was 56 kg after 1993. However, lower increases in the average EBVs were observed for the second regression coefficient, related to persistency. The RRM applied to TD records is efficient for the genetic evaluation of milk yield in the Gir dairy breed.

Pedigree verification and parentage assignment using genomic information in the Mexican Holstein population

Genealogical information is an essential tool for carrying out any genetic improvement program. The objective of this study was to determine the accuracy of pedigree information in the Mexican registered Holstein population using genomic data available in Mexico and for the US Holstein population. The study included 7,508 animals (158 sires and 7,350 cows) that were born from 2002 through 2014, registered with Holstein de México, and genotyped with single nucleotide polymorphism arrays of different densities. Parentage could not be validated for 17% of sires of cows and 12% of sires of bulls. Most (79%) of the dams of cows and the dams of bulls had no genotype available and could not be validated. A parentage test was possible for only 6,104 sires of cows, 139 sires of bulls, 1,519 dams of cows, and 33 dams of bulls. Of the animals with a parentage test, parent assignment was confirmed for 89% of sires of cows, 92% of dams of cows, 95% of sires of bulls, and 97% of dams of bulls. Parent discovery was possible for some animals without confirmed parents: 17% for sires of cows, 2.5% for dams of cows, 43% for sires of bulls, and 0% for dams of bulls. Of the 7,795 progeny tests, 777 had parent conflicts, which is an error rate of 9.97% for parental recording in the population, a rate that is similar to those recently reported for other populations. True parents for some progeny conflicts (15%) were discovered for the Mexican population, and the remaining parents were assigned as unknown. Expected effects of misidentification on rate of genetic gain could be decreased by half if genealogical errors were decreased to 5%. This study indicates that genotyping and genealogy recovery may help in increasing rates of genetic improvement in the Mexican registered Holstein population.

Genetic trend estimates for milk yield production and fertility traits of the Girolando cattle in Brazil

Annual genetic trends and selection differentials for 305-day milk yield (305MY), age at first calving (AFC), and first calving interval (FCI) were estimated by four selection paths [sires of bulls (SB), dams of bulls (DB), sires of cows (SC), and dams of cows (DC)] for Girolando dairy cattle in Brazil. A total of 12,739 lactation records were obtained from the Brazilian Girolando Breeders Association with cows calving in the period from 2000 to 2011. Two periods were involved: the first, from 1979 to 1996, corresponding to the formation and expansion of the herd, and second, from 1997 to 2007, characterized by the implementation of the breeding program of the Girolando breed. The whole period from 1979 to 2007 was also considered. The Wombat program was used to fit an animal model for the analyses. Estimated breeding values were extracted to calculate genetic trends for the four selection paths. Greater significant estimates of annual genetic changes for 305MY were obtained for the SC and SB paths, being both during the second period. The greatest annual genetic change estimates for 305MY were 43.06 and 101.97milk/yr for SC and DB, respectively, during the second period. A favorable genetic response was found for the SB and SC paths for AFC, averaging −4.24 (second period) and −0.32day/yr, respectively. For FCI, this effect was from 0.04 to 0.18 range for all paths. When all selection paths were combined, estimated annual genetic changes for 305MY and AFC were 7.40milk/yr and −0.13day/yr. Therefore, the results of this study showed that a well-designed genetic program has a positive impact on 305MY and AFC and a little or without impact on FCI in Girolando cattle over a 28-yr period.

Comparison of breeding values among cows with exceptional longevity and their contemporary herdmates in German Holsteins

Abstract. The present analysis compares the estimated breeding values (EBVs), relative breeding values (RBVs), and daughter yield deviations (YDs) of cows with exceptional longevity with their contemporary herdmates. In addition, the relative breeding values of their sires were compared among these two daughter groups; the RBVs of the sires were also compared with the proportion of their daughters with exceptional longevity. Data included 5037 sires born between 1963 and 1996 with a total of 61 988 daughter; of these sires, 486 had sired daughters that completed more than nine lactations (exceptional cows) and 4957 sires had sired the contemporary herdmates. Exceptional cows had on average significantly lower EBVs for milk yield, fat and protein yield, and significantly lower YDs for milk and protein yield in the first three lactations, significantly lower RBVs for milk production and type but significantly higher RBVs for somatic cell score and functional longevity. The sires of exceptional cows had significantly higher RBVs for somatic cell count (RZS), functional longevity (RZN), and fitness (RZFit) in comparison to the sires of contemporary herdmates. Correlations among the proportion of exceptional cows per sire and RZN, RZS as well as RZFit were positive, whereas milk production (RZM) showed a negative correlation. An increase in the number of cows with exceptional longevity may be possible through a relative total breeding value with high positive weights for RZN, RZS, and RZFit but negative weights for RZM and type (RZE).

Genetic and environmental factors affecting 305-day mature equivalent milk yield of Holstein Friesian cows in the United Arab Emirates

The main objective of this research was determining the effect of sire of cow, year and season of freshening, lactation number, and their different interactions on 305-day mature equivalent (ME) milk yield of Holstein Friesian cows in the United Arab Emirates (UAE). It also aimed to estimate sire and error variance and heritability of 305-day ME milk yield. The data was collected from AL Salamat Dairy Farm in Al Ain. The average size of the herd was 1000 animals during the experimental period. The Dairy Comp 305 computer program was used for compiling the data. The data under the study covered the years 2004 to 2007. The climatic temperature during the summer (April to September) varied from moderate to very hot. The winter (October to March) had lower temperature and higher relative humidity than the summer. All the effects were fixed except for random sire and residual error term. The overall least-square mean of the 305-day ME milk yield was 11060Å}355 kg/305 days. The data showed a significant effect of sire of cow (p≤0.001), year of freshening (p≤0.001), lactation number (p≤0.01), year x season of freshening (p≤0.01), and year of freshening x lactation number (p≤0.001) on milk yield. However, the effect of season of freshening showed non significant effect. No significant seasonal differences were found in 2004. However, in the year 2005 and 2006, the summer fresheners had significantly higher yield than those of the winter season. The 305-day ME pertaining to summer vs. winter were 11691Å}400 kg vs. 11483Å}410 kg and 11522Å}369 kg vs. 11041Å}374 kg for the year 2005 and 2006, respectively. However, the reverse was true in 2007 with the fresheners during summer that have lower 305-day ME (10286Å}372kg) than those freshening during winter (10672Å}388 kg). The differences among the three lactations were relatively high in 2004 (9837 to 12116 kg), compared to 2005 - 2006 (11267 to 11747 kg) and 2007 (9853 to 11355 kg). The heritability of 305-day ME was 0.31 indicating that a significant response to selection would be achieved through a well-designed progeny testing and cow evaluation program.

Genetic analysis of calving traits by the multi-trait individual animal model

Five alternative models were applied for analysis of dystocia and stillbirth in first and second parities. Models 1 and 2 were included only to estimate the parameters required for model 4, and models 3 and 5 are included only as comparisons to the model 4 estimates. Variance components were estimated by multi-trait REML, including cows with valid calving records for both parities. For the effects of sire of calf on first and second parities, variance components were estimated including only calvings with the same sire of calf for both parities. All heritabilities for the cow effect were quite low, but higher for dystocia than for stillbirth and higher in first parity. The sire-of-calf heritabilities were higher than the cow effect heritabilities, except for stillbirth in parity 2. Unlike the effect of cow correlations, all sire of calf correlations were >0.6, and the correlations for the same trait in parities 1 and 2 were >0.9. Thus, a multi-trait analysis should yield a significant gain in accuracy with respect to the sire of calf effects for bulls not mated to virgin heifers. A multi-trait individual animal model algorithm was developed for joint analysis of dystocia and stillbirth in first and second parities. Relationships matrices were included both for the effects of cow and sire of calf. In addition, random herd-year-season and fixed sex of calf effects were included in the model. Records were preadjusted for calving month and age. A total of 899,223 Israeli Holstein cows with first calvings since 1985 were included in the complete analysis. Approximate reliabilities were computed for both sire of cow and sire of calf effects. Correlations between these reliabilities and reliabilities obtained by direct inversion of the coefficient matrix for a sire of cow-sire of calf model were all close to 0.99. Phenotypic trends for cows born from 1983 through 2007 were economically unfavorable for dystocia and favorable for stillbirth in both parities. Genetic trends were economically unfavorable for both dystocia and stillbirth in first parity. First-parity sire of calf trends were unfavorable for dystocia, but favorable for stillbirth. All environmental trends were nearly zero. Regressions of evaluations of the complete analysis on a model including only calvings before 2011 were all >0.8. All evaluations met the Interbull Method 3 criterion for unbiasedness. Model 4, which computed genetic evaluations for all animals for all 4 traits accounting for all known relationships and correlations among the traits, is recommended for routine genetic evaluation of calving traits.

Effects of heat stress on semen characteristics of Holstein bulls estimated on a continuous phenotypic and genetic scale

Semen volume (SV), semen output (SO), semen motility (SM), number of semen doses per ejaculate (NSD) and semen concentration (SC) were analyzed on a phenotypic and quantitative genetic scale in dependency of the continuous environmental descriptor THI (=an index describing combinations of temperature with humidity). Longitudinal semen data included 10,341 observations from 562 Holstein sires kept on an AI station in the northwestern part of Germany. Statistical modeling was based on fixed and random regression methodology (RRM). In this context, the phenotypic and genetic trajectory of traits in dependency of THI was modeled by orthogonal polynomials, i.e. Legendre polynomials of order 3. A general heat stress threshold of THI=60 was identified, and indicating detrimental effects of heat stress beyond this threshold, especially on SV, SO, NSD, and SC. Least square means for semen productivity were generally higher for adult bulls, but compared to young bulls, adult bulls responded with stronger semen production losses for extremely high THI. The optimal environment for semen production was a THI in the range from 50 to 60. Detrimental impact of heat stress was reduced for bulls with longer intervals between consecutive semen collection dates. Heritabilities for semen traits were in a low to moderate range with the following maximal values: 0.18 for SV at THI 30, 0.29 for SM at THI 70, 0.26 for SO at THI 30, 0.26 for NSD at THI 58, and 0.27 for SC at THI 53. Genetic values of sires and additive genetic variances changed with alterations of THI, with highest genetic variances at the extreme ends of the continuous environmental descriptor. Genetic correlations in same traits from THI levels in great distance were lower than 0.80, and indicated genotype by environment interactions. Application of RRM allow to select sires according to THI specific breeding values, which implies an optimization of cow sire and bull sire selection for harsh environments.

Evaluation of the Criollo breed Romosinuano as purebred and crossbred cows with Brahman and Angus in Florida. II. Maternal influence on calf traits, cow weight, and measures of maternal efficiency1,2,3

The objectives of this work were to compare the Criollo breed Romosinuano as straightbred and crossbred cows with Angus and Brahman in subtropical Florida and to estimate heterosis for size traits of their calves, their own weight, and maternal efficiency traits. Cows (n = 404) were born from 2002 to 2005. After their first exposure to bulls as young cows, crossbred cows were bred to bulls of the third breed, and straightbred cows were bred in to bulls of the other 2 breeds. Calves were spring-born from 2005 through 2011. Evaluated calf (n = 1,254) traits included birth weight and weight, ADG, BCS, and hip height at weaning. Cow weight (n = 1,389) was recorded at weaning. Maternal efficiency traits evaluated included weaning weight per 100 kg cow weight, weaning weight per calving interval, and weaning weight per cow exposed to breeding (n = 1,442). Fixed effects and their interactions were investigated included sire and dam breed of cow, sire breed of calf, cow age, year, calf gender, and weaning age as a linear covariate (calf traits at weaning). Direct and maternal additive genetic effects were random in models for calf traits; only direct additive effects were modeled for cow traits. Cows sired by Angus bulls from outside the research herd had calves that were heavier at birth and weaning and greater ADG, BCS, and hip height (P < 0.05). Estimates of heterosis for weaning weight, BCS, and ADG ranged from 1.3 to 13.2% for all pairs of breeds (P < 0.05). Estimates of heterosis for birth weight (3.2 to 8.2%) and hip height (2.3%) were significant for Romosinuano-Angus and Brahman-Angus. Heterosis for cow weight was 65 ± 8 kg for Brahman-Angus (P < 0.001), and estimates for other pairs of breeds were approximately one-half that value. Heterosis for weaning weight/100 kg cow weight was 3.4 ± 0.75 kg for Romosinuano-Angus. Heterosis estimates for weaning weight/calving interval (P < 0.001) ranged from 0.08 ± 0.01 to 0.12 ± 0.01. Heterosis for weaning weight/cow exposed were 31.6 7.7, 36.9 ± 7.4, and 59.1 ± 7.5 kg for Romosinuano-Angus, Romosinuano-Brahman, and Brahman-Angus, respectively (P < 0.001). Most aspects of Romosinuano crossbred maternal performance were acceptable; maternal performance of Brahman-Angus cows excelled.

홀스타인의 유생산형질에 대한 유전모수 추정

본 연구의 목적은 여러 산차를 이용한 모델을 사용하여 유전평가 분석을 하기위하여 3개의 유량생산 형질에 대한 (공)분산 성분을 추정하고자 하였다. 모수추정을 위한 자료는 2001년부터 2009년까지의 검정자료를 이용하였고 원시자료수는 1,416,589개이며 5개의 산차형질에 대해 각각 다른 형질로 가정하여 추정하였다. 동기그룹 내 10두 이하 및 씨수소의 딸소가 10두 미만인 개체는 삭제를 하였으며 305일 유량생산이 15,000 kg을 초과하는 비유개체에 대하여 사전 데이터 가공을 실시하였다. 혈통파일은 총292,382개의 혈통자료와 1,456두의 씨수소로 구성되어진 혈통자료가 연구에 사용되었다. Sire 모형은 herd-year-season의 동기그룹과 분만월령 그리고 혈통과 5산까지 상가적 유전효과들이 적용되었으며 VCE를 이용하여 유전 (공)분산이 추정되었다. 유전율과 유전상과 그리고 잔차상관은 R 패키지를 이용하여 계산하였다. 유량에 대한 산차간 유전 상관은 0.76에서 0.98였고, 유지방량은 0.79~0.10, 유단백질량은 0.75~1.00로 나타났다. 각 산차별 유량, 유지방량, 유단백질량은 상대적으로 낮은 유전력인 0.14~0.23, 0.13~0.20이 추정되었으며 산차에 가중치로 결합된 유전력은 각 형질에서 0.29, 0.28, 0.26로 나타났다. 본 연구에서 추정된 모수들은 국가단위 유전평가분석에 사용될 수 있을 것으로 판단된다. The purpose of this study was to estimate (co) variance components of three milk production traits for genetic evaluation using a multiple lactation model. Each of the first five lactations was treated as different traits. For the parameter estimation study, a data set was set up including lactations from cows calved from 2001 to 2009. The total number of raw lactation records in first to fifth parities reached 1,416,589. At least 10 cows were required for each contemporary group, herd-year-season effect. Sires with fewer than 10 daughters were discarded. Lactations with 305d milk yield exceeding 15,000 kg were removed. In total, 1,456 sires of cows were remained after all the selection steps. A complete pedigree consisting of 292,382 records was used for the study. A sire model containing herd-year-season, caving age, and sire additive genetic effects was applied to the selected lactation data and pedigree for estimating (co) variance components via VCE. Heritabilities and genetic or residual correlations were then derived from the (co) variance estimates using R package. Genetic correlations between lactations ranged from 0.76 to 0.98 for milk yield, 0.79~1.00 for fat yield, 0.75~1.00 for protein yield. On individual lactation basis, relatively low heritability values were obtained 0.14~0.23, 0.13~0.20 and 0.14~0.19 for milk, fat, and protein yields, respectively. For the combined lactation heritability values were 0.29, 0.28, and 0.26 for milk, fat, and protein yields. The estimated parameters will be used in national genetic evaluations for production traits.

Factors associated with frequency of abortions recorded through Dairy Herd Improvement test plans

Frequency of abortions recorded through Dairy Herd Improvement (DHI) testing was summarized for cows with lactations completed from 2001 through 2009. For 8.5million DHI lactations of cows that had recorded breeding dates and were >151d pregnant at lactation termination, the frequency of recorded abortions was 1.31%. Effects of year, herd-year, month, and pregnancy stage at lactation termination; parity; breed; milk yield; herd size; geographic region; and state within region associated with DHI-recorded abortion were examined. Abortions recorded through DHI (minimum gestation of 152d required) were more frequent during early gestation; least squares means (LSM) were 4.38, 3.27, 1.19, and 0.59% for 152 to 175, 176 to 200, 201 to 225, and 226 to 250d pregnant, respectively. Frequency of DHI-recorded abortions was 1.40% for parity 1 and 1.01% for parity ≥8. Abortion frequency was highest from May through August (1.42 to 1.53%) and lowest from October through February (1.09 to 1.21%). Frequency of DHI-recorded abortions was higher for Holsteins (1.32%) than for Jerseys (1.10%) and other breeds (1.27%). Little relationship was found between DHI-recorded abortions and herd size. Abortion frequencies for effects should be considered to be underestimated because many abortions, especially those caused by genetic recessives, go undetected. Therefore, various nonreturn rates (NRR; 60, 80, …, 200d) were calculated to document pregnancy loss confirmed by the absence of homozygotes in the population. Breeding records for April 2011 US Department of Agriculture sire conception rate evaluations were analyzed with the model used for official evaluations with the addition of an interaction between carrier status of the service sire (embryo's sire) and cow sire (embryo's maternal grandsire). Over 13million matings were examined using various NRR for Holstein lethal recessive traits (brachyspina and complex vertebral malformation) and undesirable recessive haplotypes (HH1, HH2, and HH3) as well as >61,000 matings for a Brown Swiss haplotype (BH1), and 670,000 matings for a Jersey haplotype (JH1). Over 80% of fertility loss occurred by 60d after breeding for BH1, HH3, and JH1, by 80d for HH2, by 100d for BY, and by 180d for HH1. For complex vertebral malformation, fertility loss increased from 40 to 74% across gestation. Association of undesirable recessives with DHI-recorded abortions ranged from 0.0% for Jerseys to 2.4% for Holsteins.

The sensitivity of predicted financial and genetic gains in Holsteins to changes in the economic value of traits

The objective of this study was to assess the impact of using different relative economic values (REVs) in selection indices on predicted financial and trait gains from selection of sires of cows and on the choice of leading Holstein bulls available in the UK dairy industry. Breeding objective traits were milk yield, fat yield, protein yield, lifespan, mastitis, non-return rate, calving interval and lameness. Relative importance of a trait, as estimated by a.h(2), was only moderately related to the rate of financial loss or total economic merit (ΔTEM) per percentage under- or overestimation of REV (r = 0.38 and 0.29, respectively) as a result of the variance-covariance structure of traits. The effects on TEM of under- or overestimating trait REVs were non-symmetrical. TEM was most sensitive to incorrect REVs for protein, fat, milk and lifespan and least sensitive to incorrect calving interval, lameness, non-return and mastitis REVs. A guide to deciding which dairy traits require the most rigorous analysis in the calculation of their REVs is given. Varying the REVs within a fairly wide range resulted in different bulls being selected by index and their differing predicted transmitting abilities would result in the herds moving in different directions in the long term (20 years). It is suggested that customized indices, where the farmer creates rankings of bulls tailored to their specific farm circumstances, can be worthwhile.

Association of length of pregnancy with other reproductive traits in dairy cattle.

The experiment involved observations of 2,514 Holstein-Friesian cows to determine the effects of environmental factors (cow’s age, calving season, weight and sex of calves, housing system) and genetic factors on gestation length in dairy cattle and the correlation between gestation length and other reproductive traits (calving ease, stillbirth rates and placental expulsion). Genetic parameters were estimated based on the sires of calved cows (indirect effect) and the sires of live-born calves (direct effect). The following factors were found to contribute to prolonged gestation: increasing cow’s age, male fetuses and growing fetus weight. Optimal gestation length was determined in the range of 275–277 days based on calving ease and stillbirth rates. The heritability of gestation length was estimated at 0.201–0.210 by the direct effect and 0.055–0.073 by the indirect effect. The resulting genetic correlations suggest that the efforts to optimize (prolong) gestation length could exert an adverse influence on the breeding value of bulls by increasing perinatal mortality and calving difficulty. The standard errors of the investigated parameters were relatively high, suggesting that any attempts to modify gestation length for the purpose of improving calving ease and reducing stillbirth rates should be introduced with great caution.

Deterministic models of breeding scheme designs that incorporate genomic selection

A deterministic model to calculate rates of genetic gain and inbreeding was used to compare a range of breeding scheme designs under genomic selection (GS) for a population of 140,000 cows. For most schemes it was assumed that the reliability of genomic breeding values (GEBV) was 0.6 across 4 pathways of selection. In addition, the effect of varying reliability on the ranking of schemes was also investigated. The schemes considered included intense selection in male pathways and genotyping of 1,000 young bulls (GS-Y). This scheme was extended to include selection in females and to include a “worldwide” scheme similar to GS-Y, but 6 times as large and assuming genotypes were freely exchanged between 6 countries. An additional worldwide scheme was modeled where GEBV were available through international genetic evaluations without exchange of genotypes. Finally, a closed nucleus herd that used juvenile in vitro embryo transfer in heifers was modeled so that the generation interval in female pathways was reduced to 1 or 2 yr. When the breeding schemes were compared using a GEBV reliability of 0.6, the rates of genetic gain were between 59 and 130% greater than the rate of genetic gain achieved in progeny testing. This was mainly through reducing the generation interval and increasing selection intensity. Genomic selection of females resulted in a 50% higher rate of genetic gain compared with restricting GS to young bulls only. The annual rates of inbreeding were, in general, 60% lower than with progeny testing, because more sires of bulls and sires of cows were selected, thus increasing the effective population size. The exception was in nucleus breeding schemes that had very short generation intervals, resulting in higher rates of both gain and inbreeding. It is likely that breeding companies will move rapidly to alter their breeding schemes to make use of genomic selection because benefits to the breeding companies and to the industry are considerable.

Recursive relationships between milk yield and somatic cell score of Canadian Holsteins from finite mixture random regression models

Finite mixture, multiple-trait, random regression animal models with recursive links between phenotypes for milk yield and somatic cell score (SCS) on the same test-day were applied to first lactation Canadian Holstein data. All models included fixed herd-test-day effects and fixed regressions within region–age at calving–season of calving classes, and animal additive genetic and permanent environmental regressions with random coefficients. Causal links between phenotypes for milk yield and SCS were fitted separately for records from healthy cows and cows with a putative, subclinical form of mastitis. Bayesian methods via Gibbs sampling were used for the estimation of model parameters. Bayes factors indicated superiority of the model with recursive link from milk to SCS over the reciprocal recursive model and the standard multiple-trait model. Differences between models measured by other, single-trait model comparison criteria (i.e., weighted mean squared error, squared bias, and correlation between observed and expected data) were negligible. Approximately 20% of test-day records were classified as originating from cows with mastitis in recursive mixture models. The proportion of records from cows infected with mastitis was largest at the beginning of lactation. Recursive mixture models exhibited different distributions of data from healthy and infected cows in different parts of lactation. A negative effect of milk to SCS (up to −0.15 score points for every kilogram of milk for healthy cows from 5 to 45 d in milk) was estimated for both mixture components (healthy and infected) in all stages of lactation for the most plausible model. The magnitude of this effect was stronger for healthy cows than for cows infected with mastitis. Different patterns of genetic and environmental correlations between milk and SCS for healthy and infected records were revealed, due to heterogeneity of structural coefficients between mixture components. Estimated breeding values for SCS from the best fitting model for sires of infected daughters were more related to estimated breeding values for the same trait from the regular multiple-trait model than evaluations for sires of mastitis-free cows.

Genetic and environmental factors that affect gestation length in dairy cattle

Genetic and environmental factors that might affect gestation length (GL) were investigated. Data included information from >11million parturitions from 1999 through 2006 for 7 US dairy breeds. Effects examined were year, herd-year, month, and age within parity of conception; parturition code (sex and multiple-birth status); lactation length and standardized milk yield of cow; service sire; cow sire; and cow. All effects were fixed except for service sire, cow sire, and cow. Mean GL for heifers and cows, respectively, were 277.8 and 279.4 d for Holsteins, 278.4 and 280.0 d for Jerseys, 279.3 and 281.1 d for Milking Shorthorns, 281.6 and 281.7 d for Ayrshires, 284.8 and 285.7 d for Guernseys, and 287.2 and 287.5 d for Brown Swiss. Estimated standard deviations of GL were greatly affected by data restrictions but generally were approximately 5 to 6 d. Year effects on GL were extremely small, but month effects were moderate. For Holstein cows, GL was 2.0 d shorter for October conceptions than for January and February conceptions; 4.7 and 5.6 d shorter for multiple births of the same sex than for single-birth females and males, respectively; 0.8 d longer for lactations of ≤250 d than for lactations of ≥501 d; and 0.6 d shorter for standardized yield of ≤8,000kg than for yield of ≥14,001kg. Estimates for GL heritability from parities 2 to 5 were 33 to 36% for service sire and 7 to 12% for cow sire; corresponding estimates from parity 1 were 46 to 47% and 10 to 12%. Estimates of genetic correlations between effects of service sire and cow sire on GL were 0.70 to 0.85 for Brown Swiss, Holsteins, and Jerseys, which indicates that those traits likely are controlled by many of the same genes and can be used to evaluate each other. More accurate prediction of calving dates can help dairy producers to meet management requirements of pregnant animals and to administer better health care during high-risk phases of animals’ lives. However, intentional selection for either shorter or longer GL is not recommended without consideration of its possible effect on other dependent traits (e.g., calving ease and stillbirth).