Let R be a commutative Noetherian ring with non-zero identity, $$\mathcal {F}$$ a filtration of $${{\mathrm{Spec}}}(R)$$ which admits an R-module X, and $${{\mathrm{C}}}_R(\mathcal {F},X)$$ the Cousin complex for X with respect to $$\mathcal {F}$$ . In this paper, we first introduce the Cousin functor and the Cousin spectral sequences. Then for non-negative integers s, t and a finite R-module N, we study the membership of R-modules $${{\mathrm{H}}}^{s-1}({{\mathrm{Ext}}}^t_R(N,{{\mathrm{C}}}_R(\mathcal {F},X)))$$ and $${{\mathrm{Ext}}}^{s}_R(N,{{\mathrm{H}}}^{t-1}({{\mathrm{C}}}_R(\mathcal {F},X)))$$ in Serre subcategories of the category of R-modules and find some conditions for validity of an isomorphism between them. Finally, we use these results to present some facts about the vanishing and finiteness of Cousin cohomology modules.
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