It is well documented that systemic racism and social injustice result in health inequities for communities of color, including premature death. To date, more than 260 municipalities across the United States have declared racism as a public health crisis. In January 2021, the Nation’s Health, a monthly American Public Health Association newsletter, acknowledged Genesee County, Michigan, as one of the communities leading the work in operationalizing these declarations. This research highlights community engagement and participatory processes, models, and tools used to operationalize racism as a public health crisis in Genesee County. A participatory approach grounded in community-based participatory research (CBPR) methods was used to operationalize Genesee County’s resolution declaring racism a public health crisis. To ensure our efforts centered community voices, experiences, and priorities, our methodology consisted of: 1) hosting community dialogues focused on systemic racism; 2) the novel application of a committee composition matrix to develop a geographically and socially diverse Community Action Council to serve as the decision-making body for our strategic plan to identify and address systemic racism within Genesee County; 3) the development of a draft county-wide strategic plan; and 4) focus groups to review and provide feedback on the drafted strategic plan. CBPR provides guidance for effective community engagement and ensures that community voices are centered when identifying effective responses to systemic racism. CBPR principles also foster co-ownership of solutions, increasing trust, transparency, and accountability between researchers, community members, and other stakeholders.