We study correlation functions of local operators and Wilson loop expectation values in the planar limit of a 4d N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 2 superconformal SU(N) YM theory with hypermultiplets in the symmetric and antisymmetric representations of the gauge group. This so called E theory is closely related to N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 4 SYM and has a holographic description in terms of a ℤ2 orientifold of AdS5 × S5. Using recent matrix model results based on supersymmetric localization we develop efficient numerical methods to calculate two- and three-point functions of certain single trace operators as well as 1/2-BPS Wilson loop expectation values as a function of the ’t Hooft coupling λ. We use our numerical results to arrive at simple analytic expressions for these correlators valid up to sixth order in the λ−1/2 strong coupling expansion. These results provide explicit field theory predictions for the α′ corrections to the supergravity approximation of type IIB string theory on the AdS5 × S5/ℤ2 orientifold.