Cooperative Effect Research Articles

Intellectual Property Rights Protection Mechanisms Harmonization in the EAEU Preferential Trade Agreements

In this article, the subject of scientific interest is the need to harmonize the Eurasian Economic Union (EAEU) legal frameworks on the protection of intellectual property rights as the rapid economic development of states cannot be achieved without effective international cooperation. The theoretical significance of this work is comprised by establishing how effective the mechanism for protecting intellectual property rights in the EAEU is at the moment, and the practical significance is in suggesting ways to increase the effectiveness of such protection so that investors have additional guarantees of their rights’ protection. The research methodology is based on the formal dogmatic approach to the interpretation of existing regulatory material with elements of socio-legal research, which consists of evaluating the proposed legal novels at the viewpoint of their practical application, in particular, given the scale of international trade cooperation between the EAEU and the country in question, expressed by the means of the statistical data on foreign trade turnover for 2021. The main results of this study are proposals for drafting the preferential agreements of the EAEU, which is considered as a contribution to the scientific base of research on improving the regulatory frameworks of the EAEU and, from a practical point of view, will help to maximize the potential for cooperation between the EAEU and the states with which preferential agreements are concluded.

Green Energy Co-operation Mechanisms Between China and Countries along the Belt and Road: The Role of Chinese Local Governments and International Organizations

As global climate issues have intensified, promoting green energy has become the key to solving the problem. This paper explores the role of Chinese local governments and international organizations in promoting green energy cooperation under the Belt and Road Initiative (BRI). It highlights the importance of such partnerships for accelerating energy transitions in underdeveloped countries. The study argues that local governments in China have translated central policies into local action, supporting the development of green energy projects along the Belt and Road through policy responses, promoting local projects, and mobilizing local businesses to invest. At the same time, this article classifies the international organizations participating in the BRI as platform-type organizations and participatory organizations. The former provides effective financial tools for Belt and Road green energy projects, and the latter uses existing influence to promote the construction of an international discourse on a consensus-driven green Belt and Road. Effective green energy cooperation requires a multi-level approach that includes policy adaptations, infrastructure construction, and knowledge-sharing mechanisms. Research on the role and influence of actors within cooperation networks and the relationships among multiple actors may provide a reference for broader green cooperation on a global scale.

Diastereoselective Polypseudorotaxane Formation with Planar Chiral Pillar[5]arenes via Co-crystallization Processes.

As the number of chiral ring molecules in chiral polyrotaxane increases, the number of possible stereoisomers exponentially increases. Consequently, the selective synthesis of a specific stereoisomer becomes much more challenging. To address this problem, we co-crystallized poly(ethylene glycol) and a diastereomeric ring molecule, pillar[5]arene, in the solid state. The co-crystallization formed polypseudorotaxanes with a high diastereomeric excess (ca. 88% de), meaning that polypseudorotaxanes containing (S, pS) stereoisomer pillar[5]arene rings were synthesized selectively. By contrast, in a solution and evaporation systems, the selectivity remained low (ca. 10% de). The results suggested that the packing effect by the co-crystallization contributed to the denser assembly of ring molecules on the polymeric chain, resulting in the diastereoselective formation. High diastereoselectivity was also observed even in higher-molecular-weight poly(ethylene glycol)s. These selectivities arose from the cooperative effects of the ring molecules on the polymeric chain, which were supported by calculating the stabilization energy.

Diastereoselective Polypseudorotaxane Formation with Planar Chiral Pillar[5]arenes via Co‐crystallization Processes

As the number of chiral ring molecules in chiral polyrotaxane increases, the number of possible stereoisomers exponentially increases. Consequently, the selective synthesis of a specific stereoisomer becomes much more challenging. To address this problem, we co‐crystallized poly(ethylene glycol) and a diastereomeric ring molecule, pillar[5]arene, in the solid state. The co‐crystallization formed polypseudorotaxanes with a high diastereomeric excess (ca. 88% de), meaning that polypseudorotaxanes containing (S, pS) stereoisomer pillar[5]arene rings were synthesized selectively. By contrast, in a solution and evaporation systems, the selectivity remained low (ca. 10% de). The results suggested that the packing effect by the co‐crystallization contributed to the denser assembly of ring molecules on the polymeric chain, resulting in the diastereoselective formation. High diastereoselectivity was also observed even in higher‐molecular‐weight poly(ethylene glycol)s. These selectivities arose from the cooperative effects of the ring molecules on the polymeric chain, which were supported by calculating the stabilization energy.

Muramyl dipeptide potentiates Staphylococcus aureus lipoteichoic acid-induced nitric oxide production via TLR2/NOD2/PAFR signaling pathways

Lipoteichoic acid (LTA) and peptidoglycan (PGN) are considered as key virulence factors of Staphylococcus aureus, which is a representative sepsis-causing Gram-positive pathogen. However, cooperative effect of S. aureus LTA and PGN on nitric oxide (NO) production is still unclear despite the pivotal roles of NO in initiation and progression of sepsis. We here evaluated the cooperative effects of S. aureus LTA (SaLTA) and muramyl dipeptide (MDP), the minimal structure of PGN, on NO production in both a mouse macrophage-like cell line, RAW 264.7 and mouse bone marrow-derived macrophages (BMMs). Although MDP alone did not affect NO production, MDP potently enhanced SaLTA-induced NO production via the expression of inducible NO synthases. The enhanced NO production was ameliorated in BMMs from TLR2-, CD14-, MyD88-, and NOD2-deficient mice. Moreover, the augmented SaLTA-induced NO production by MDP was attenuated by inhibitors specific for PAFR and MAP kinases. Furthermore, MDP also potently increased SaLTA-induced activities of STAT1, NF-κB, and AP-1 transcription factors, and specific inhibitors for these transcription factors suppressed the elevated NO production. Collectively, these results demonstrated that MDP potentiates SaLTA-induced NO production via TLR2/NOD2/PAFR, MAP kinases signaling axis, resulting in the activation of NF-κB, AP-1 and STAT1 transcription factors.

In Situ Synthesis of Iron-Based Porphyrin Metal-Organic Frameworks for the Baeyer-Villiger Oxidation Using Air as an Oxidant.

Iron-based porphyrin metal-organic frameworks (PMOFs) are a new type of material with good stability, catalytic activities, and reusability, which have broad application prospects. However, the synthesis of iron-based PMOFs with different metalloporphyrin units requires a considerable amount of reagents and time. Herein, an in situ synthesis method was developed to simplify the synthetic process of iron-based PMOFs. A series of highly stable iron-based PMOFs (Msitu-PMOF-3(Fe) (M = Fe, Co, Ni, Cu, Pd)) were synthesized in one pot without the preparation of metalloporphyrin ligands in advance. This synthesis method is simpler and more efficient, saving considerable time and material costs. The resultant Msitu-PMOF-3(Fe) exhibits a high tolerance to aqueous solutions with pH ranging from 0 to 11, as well as various organic solvents. The catalytic experiments show that both Fesitu-PMOF-3(Fe) and Cositu-PMOF-3(Fe) can catalyze the Baeyer-Villiger oxidation of cyclohexanone using air as an oxidant at 35 °C. Moreover, when the mixtures of Fesitu-PMOF-3(Fe) and Cositu-PMOF-3(Fe) were employed as catalyst, they can exert a cooperative catalysis effect, resulting in a significantly enhanced catalytic activity compared to a single component. The mild reaction condition, high catalytic efficiency, and excellent selectivity endow this catalytic system with a good application prospect. This work not only provides a new approach for the synthesis of iron-based PMOFs but also offers guidance for the Baeyer-Villiger oxidation reactions using air under mild conditions.

Efficiency of Police Cooperation in Criminal Investigations

Police cooperation is essential not only to investigate crime, but also to prevent it. Sharing information and best practices between law enforcement agencies allows early identification of threats, which can lead to prompt and effective interventions. At the same time, working together can reduce legislative or procedural disparities between states, which helps to strengthen joint efforts to fight crime. In addition to legal and operational challenges, police cooperation also raises ethical, privacy and data protection issues. In the digital age, the exchange of information between police agencies must comply with strict data protection standards in line with national and international legislation, such as the General Data Protection Regulation (GDPR) in the European Union. Thus, police cooperation is an indispensable tool in criminal investigations, offering the possibility to go beyond the geographical and legal limits imposed by national borders. However, its effectiveness depends on a clear legislative framework, mutual trust between partners and the adoption of modern technologies to facilitate real-time communication and information exchange. Police cooperation is an essential element in the fight against contemporary crime, but its effectiveness depends on resolving the legislative and operational problems that sometimes prevent effective inter-agency cooperation. Technological development and adaptation to new forms of crime also remain major challenges in this area.

Cooperative dual-actor proximal policy optimization algorithm for multi-robot complex control task

This paper introduces a novel multi-agent Deep Reinforcement Learning (DRL) framework named the Cooperative Dual-Actor Proximal Policy Optimization (CDA-PPO) algorithm, designed to address complex humanoid robot cooperative learning control tasks. Effective cooperation among multiple humanoid robots, particularly in scenarios involving complex walking gait control and external disturbances in dynamic environments, is a critical challenge. This is especially pertinent for tasks requiring precise coordination and control, such as joint object transportation. In various real-life scenarios, humanoid robots might need to cooperate to carry large objects in many scenarios. This capability is crucial for logistics, manufacturing, intelligent transportation, and search-and-rescue missions applications. Humanoid robots have gained significant popularity, and their use in these cooperative tasks is becoming more common. To address this challenge, we propose CDA-PPO, which introduces a learning-based communication platform between agents and employs two distinct policy networks for each agent. This dual-policy approach enhances the robots’ ability to adapt to complex interactions and maintain stability while performing intricate tasks. We demonstrate the efficacy of CDA-PPO in a cooperative object-transportation scenario, where two humanoid robots collaborate to carry a table. The experimental results show that CDA-PPO significantly outperforms traditional methods, such as Independent PPO (IPPO), Multi-Agent PPO (MAPPO), and Multi-Agent Twin Delayed Deep Deterministic Policy Gradient (MATD3), in terms of training efficiency, stability, reward acquisition, and humanoid robot cooperative balance control with effective coordination between robots. The findings underscore the potential of CDA-PPO to advance the field of cooperative multi-agent control problems, proposing the way for future research in complex robotics applications.

Pre-hospital emergency care personnel’s challenges in providing care in mass casualty incidents: A qualitative study

BackgroundIn incidents with mass casualties, pre-hospital emergency medical services personnel (prehospital EMS personnel) face challenges that can impact their management of the scene and, by extension, their professional performance. The present study investigated the challenges faced by prehospital EMS personnel in mass casualty incidents in the south of Iran. MethodsThis is a qualitative-descriptive study. The subjects were selected via purposeful sampling. Accordingly, 23 prehospital EMS personnel were interviewed in 23 semi-structured, individual, in-depth interviews. Graneheim and Lundman’s method was used to collect the data. ResultsThree themes and eight subthemes emerged from the qualitative data analysis. The three main themes were challenges related to professional capabilities, challenges related to organizational management inefficiency, and challenges related to lack of effective inter-organizational coordination and cooperation in crisis management. ConclusionThe challenges faced by prehospital EMS personnel in mass casualty incidents encompasses challenges related to professional capabilities, challenges related to organizational management inefficiency, and challenges related to lack of effective inter-organizational coordination and cooperation in crisis management. The results of this study can be used by senior medical emergency services managers to identify the challenges of pre-hospital emergency care personnel in mass casualty incidents and take the necessary measures to eliminate them to improve the quality of pre-hospital care in mass casualty incidents.

Corrosion and wear resistance of ultrasonic vibration-assisted laser cladded Fe-based crystal/amorphous composite coatings

The ultrasonic vibration (UV) is applied during the laser cladding process of Fe88.83Si6.21B2.51Cr2.45 (wt. %) amorphous powders. The microstructure evolution and properties of the Fe-based crystal/amorphous composite coatings with and without UV were investigated in detail. The results reveal a significant decrease of 55.8% in the average grain size within the UV coating, accompanied by a 35.9% reduction in the length of columnar grains at the interface, which is primarily attributed to the acoustic streaming and cavitation effects of ultrasound. The average microhardness value of coatings rises from 659 ±33 HV0.2 to 873 ±48 HV0.2. Meanwhile, the coatings with UV exhibit outstanding wear resistance, with a 38.2% reduction in wear rate compared to normal coatings. The corrosion mechanism of the coatings is pitting corrosion and the corroded surface of the coating with UV displays a relatively smaller pitting area. The enhancement mechanism for properties by U V can be the cooperative effect of the fine-grain strengthening and the amorphous phase strengthening.

First-principles study of Y, Ca microalloyed Mg-Zn alloy

This article investigates the complex effects of Y and Ca alloying on the G.P. zones ( parallel to {0001}Mg)and G.P.1 zones ( parallel to {2-1-10}Mg) in Mg-Zn alloys, as well as their corresponding changes in thermal stability, electronic structure, and mechanical properties, using first-principles calculations. The addition of Y significantly enhances the thermal stability of both the G.P. and G.P.1 zones, whereas the effect of Ca is more limited, mainly enhancing the thermal stability of the one-atomic layer G.P. zones, but possibly decreasing the thermal stability in other areas. In the combined alloying of Y and Ca, the cooperative effect optimizes the thermal stability of the one-atomic layer and half-atomic layer G.P.1 zones, but reduces the thermal stability of other G.P. zones. Through studying the local density of states and the atomic radial distribution function, it is revealed that the higher stability of the half-atomic layer G.P. zones compared to the one-atomic layer G.P. zones is due to more Mg-Zn and Mg-Mg bonds, whereas the one-atomic layer G.P.1 zones exhibits higher stability because of shorter and more stable Zn-Zn, Mg-Zn, and Zn-Mg bonds. The electronic structure analysis shows that Y mainly appears in the alloy in the form of electron localization, readily forming ionic bonds with Mg and Zn, which is a key reason for its effective alloying results. In contrast, Ca, as well as the alloying of Y and Ca, do not form effective bonds on the energy levels from -8eV to -5eV, explaining their weaker alloying effects. Additionally, the study of mechanical properties indicates that the G.P. zones of pure Zn, due to its significant difference in shear modulus from the magnesium matrix, is not easily strengthened by dislocation shearing and thus mainly strengthened through the Orowan mechanism. The addition of Y significantly increases the strength and hardness of the one-atomic layer G.P. zones, but decreases the ductility. The addition of Ca changes the anisotropy of the Young's modulus of the one-atomic layer G.P. zones, while the combined effect of Y and Ca greatly alters the anisotropy of the shear modulus of this phase. These findings provide important theoretical guidance and insights for the design and application of Mg-Zn alloys.

Construction of 2D/2D heterostructure with porous few layer g-C3N4 and NiCo2O4 nanosheets towards electromagnetic wave absorption

Developing high-performance materials with ultra-high reflection loss (RL ≤ -65 dB) for electromagnetic wave (EMW) absorption is pivotal to address electromagnetic pollution, but it is still challenging. Herein, a two-dimensional (2D)/2D PFL g-C3N4/NiCo2O4 heterostructure with porous few-layer g-C3N4 (PFL g-C3N4) and ultrathin NiCo2O4 nanosheets has been prepared by self-assembly, hydrothermal reaction, and calcination strategies. The 2D/2D heterostructure exhibits extraordinary EMW absorption property, achieving a reflection loss (RL) value of -68.59 dB and an effective absorption bandwidth (EAB) of 1.92 GHz at a matching thickness of 2.5 mm. As expected, the porous few layer g-C3N4 nanosheets provide rich interface which increases multiple reflection paths and enhances the conduction loss. The cooperative effects of magnetic loss, dielectric loss, and impedance matching contribute to the exceptional EMW absorption property of PFL g-C3N4/NiCo2O4 (2D/2D) heterostructure. The potential of PFL g-C3N4/NiCo2O4 in actual radar stealth is verified through radar scattering cross-section (RCS) simulation. This work paves the way for utilizing 2D/2D heterostructure as an ultra-efficient EMW absorbers.

GUESS: GradUally Enriching SyntheSis for Text-Driven Human Motion Generation.

In this article, we propose a novel cascaded diffusion-based generative framework for text-driven human motion synthesis, which exploits a strategy named GradUally Enriching SyntheSis (GUESS as its abbreviation). The strategy sets up generation objectives by grouping body joints of detailed skeletons in close semantic proximity together and then replacing each of such joint group with a single body-part node. Such an operation recursively abstracts a human pose to coarser and coarser skeletons at multiple granularity levels. With gradually increasing the abstraction level, human motion becomes more and more concise and stable, significantly benefiting the cross-modal motion synthesis task. The whole text-driven human motion synthesis problem is then divided into multiple abstraction levels and solved with a multi-stage generation framework with a cascaded latent diffusion model: an initial generator first generates the coarsest human motion guess from a given text description; then, a series of successive generators gradually enrich the motion details based on the textual description and the previous synthesized results. Notably, we further integrate GUESS with the proposed dynamic multi-condition fusion mechanism to dynamically balance the cooperative effects of the given textual condition and synthesized coarse motion prompt in different generation stages. Extensive experiments on large-scale datasets verify that GUESS outperforms existing state-of-the-art methods by large margins in terms of accuracy, realisticness, and diversity.

Increasing the Effectiveness and Efficiency of Local MSME Consignment Cooperation with the Portal Vendor System

MSMEs have an important role in the Indonesian economy, but they face challenges in adapting to the digital era and establishing effective collaborations with retail companies. This study aims to develop and evaluate a vendor portal system that can overcome this challenge by increasing the effectiveness and efficiency of consignment cooperation between local MSMEs and retail companies. Using a qualitative descriptive method, this study analyzes the impact of the implementation of the vendor portal system on the consignment business process, including operational efficiency, transparency, and collaboration between the two parties. The results show that the vendor portal system has succeeded in improving operational efficiency, providing real-time transparency of sales and inventory data, and facilitating better communication between MSMEs and retail companies. In addition, this system also supports the government's program in encouraging MSMEs to "Go Digital" and "Upgrade Class".

시·도 기초학력지원센터 설치·운영 방식에 대한 이해관계자 인식

Purpose: This study analyzes the installation and operation of local center for basic skills support, focusing on key issues. It addresses the adoption of private outsourcing versus direct management by educational authorities. Methods: Stakeholder perceptions of the operation of local center for basic skills support were analyzed using the frameworks of policy delivery structure, private sector involvement, and collaborative governance. Data were collected through in-depth interviews with education office officials, teachers, and private institution representatives directly involved in the centers' operations. Results: The research findings can be summarized as follows: First, effective cooperation between the central and local governments was crucial for implementing the basic academic support policy. Second, outsourcing to private institutions offered flexibility and expertise, while direct government management ensured consistency and accountability. Third, collaboration between the central government, local education offices, and private institutions was vital for improving basic academic skills and increasing policy effectiveness. Conclusion: This research offers significant insights into decision-making regarding the operational strategies of local center for basic skills support. By incorporating practitioners' experiences and perceptions, it provides practical recommendations for improving the delivery system to enhance basic academic support policies.

Fabrication of nanoparticle-reinforced composite hydrogel for improved durability, antifouling, and thrombosis-resistance in arteriovenous grafts

Arteriovenous grafts are routinely designed to provide a deliberate connection between an artery and vein in patients during hemodialysis. The commonly used grafts present significant drawbacks such as thrombosis, bacterial infection, and biofouling which prevents their functionality. To endow hydrogels with improved anti-thrombosis, stable antifouling, and strong mechanical strength, a surface-modified nanoparticle-reinforced nanohybrid hydrogel is developed. In brief, zwitterionic sulfobetaine methacrylate (SBMA) is coated on bentonite clay (BC) nanoparticles via a simple method. BC-SBMA nanoparticles were then loaded onto sodium alginate /polyvinyl alcohol hydrogel composite. Calcium chloride (Ca2+) crosslinking is employed to form stable network and optimize polyvinyl alcohol/sodium alginate (PS) hydrogel composite. BC-SBMA particles were dispersed into PS hydrogel and crosslinked to form nanohybrid hydrogel (PS@BC-SBMA). The nanohybrid hydrogel was characterized for its morphological, mechanical, physicochemical, antibacterial, biocompatibility, antifouling, ex-vivo anti-thrombogenic, and in-vivo anti-inflammatory properties. The results revealed that the presence ofBC-SBMA particles boosted the mechanical strength and facilitated biocompatibility. The presence of zwitterionic polymers provided excellent antifouling properties toward blood platelets, unnecessary proteins, and bacterial strains. Hence, the cooperative effects of the nanohybrid hydrogel such as biocompatibility, antifouling, and mechanical properties lead to a desirable candidate for blood-contacting implants.

Cooperative effects of quaternary ammonium salt collectors and cationic polyacrylamide on flotation separation of diaspore and kaolinite: Experimental study and simulation

In the presence of depressant cationic polyacrylamide (CPAM), three quaternary ammonium salt as collectors were used in the flotation separation of diaspore and kaolinite, respectively. The flotation results of single minerals showed that the high recovery of the kaolinite and the low recovery of diaspore were gained, which indicated that the floatability of kaolinite was hardly affected while the floatability of diaspore was obviously weakened by using Gemini collector and CPAM under the conditions of pulp pH value of 6. The mass ratio of Al2O3 to SiO2 (A/S) was also increased from 4.86 to 8.90. FTIR spectra, adsorption capacity of collectors and zeta potential analysis illustrated that the maximum difference value in adsorption capacity of Gemini collector on the surface of kaolinite and diaspore was obtained because of the differences of the collectors in the presence of CPAM. This phenomenon was further supported by molecular dynamics simulation analysis and XPS analysis. The opinion can be provided that the difference between kaolinite and diaspore was enlarged by regulating the cooperation of the collector and the depressant for increasing the flotation separation of minerals.

ASEAN-China Transport Co-operation: A Pathway to Enhance Export Trade and Mutual Benefits

Against the backdrop of global economic integration, economic cooperation between China and ASEAN has become increasingly close. As an economic organisation in Southeast Asia, ASEAN has enhanced the economic strength and international influence of the entire region by promoting economic integration among its member countries. This study examines the interaction between China and ASEAN countries in the area of transport cooperation and the potential impact of these cooperation projects on bilateral trade volumes through case studies of the China-Laos Railway (CLR) and the Kunming-Bangkok Expressway (KBA). The study uses annual import and export statistics provided by the National Bureau of Statistics (NBS) to reveal the direct and indirect impacts of transport infrastructure improvements on trade flows by comparing the growth rates of China's imports and exports of goods with the partner countries before and after the co-operation with the growth rates with ASEAN countries. The results show a significant trade-boosting effect of transport infrastructure cooperation between China and ASEAN countries. The opening of the CLR and the KBA not only improved the efficiency and quality of goods transport, but also promoted the economic development of the countries along the routes. Through these transport infrastructure projects, the trade volume between China and ASEAN countries has increased significantly, the trade structure has been optimised, logistics efficiency has been improved, industrial complementarity has been enhanced, and substantial economic benefits have been brought to both sides.

Preservation of Luminescent Properties of Zinc Complexes in the Solid State by Accumulating into Polyhedral Oligomeric Silsesquioxane

Multinuclear complexes have attracted great attention because of their superior properties originating from the cooperative effects between the metal ions. In this study, we synthesized polynuclear zinc complexes by chelation between the side‐chains of polyhedral oligomeric silsesquioxane (POSS). From the NMR spectroscopy, high‐resolution mass spectrometry and Fourier transform infrared spectroscopy (FT‐IR), it was confirmed the four equivalents of zinc ions were coordinated to the single POSS molecule. Optical measurements indicated that luminescent properties can be preserved even in the solid state. The three‐dimensional structure of POSS should play a significant role in suppressing concentration quenching followed by solid‐state emission properties.

ORGANIZATION OF MEDICAL SERVICES FOR TRAUMA PATIENTS: CURRENT REQUIREMENTS AND BEST PRACTICES OF COOPERATION BETWEEN TRAUMATOLOGISTS AND THERAPISTS

Modern requirements for the organization of medical services for traumatological patients reflect the need for effective cooperation between specialists in traumatology and therapy. It is important to note that today there are a large number of unique programs that allow for the collective work of specialists in various fields in order to organize better medical care. This article examines the unique practices of cooperation between these specialties in order to optimize the diagnosis, treatment and rehabilitation of patients with traumatic injuries in age. The work involves not only therapists, traumatologists, but also other specialists in related fields who can assist in the rehabilitation of the patient. The analysis of the state and problems of multidisciplinary treatment of traumatologists includes answers only from the medical staff of regional trauma centers and end-treatment centers treating seriously injured people. Special attention is paid to the coordination of efforts between doctors of various profiles, the exchange of information, the use of innovative methods and technologies. The results of the study will improve the quality of medical care for trauma patients and make a significant contribution to the development of medical practice in general. The critical importance of collaboration between traumatologists and therapists is to ensure a comprehensive approach to the treatment of patients with traumatic conditions. Research in the field of organization of medical services for traumatological patients is important for the development of modern medicine. It provides an opportunity to create new formats and programs of medical care for the rapid rehabilitation of patients. New approaches contribute to improving current medical processes and improving the quality of life of society.