ABSTRACTIn recent years, with the significant increase in the volume of three‐dimensional medical image data, three‐dimensional medical models have emerged. However, existing methods often require a large number of model parameters to deal with complex medical datasets, leading to high model complexity and significant consumption of computational resources. In order to address these issues, this paper proposes a 3D Lightweight Volume Convolutional Neural Network (3D LVCN), aiming to achieve efficient and accurate volume segmentation. This network architecture combines the design principles of convolutional neural network modules and hierarchical transformers, using large convolutional kernels as the basic framework for feature extraction, while introducing 1 × 1 × 1 convolutional kernels for deep convolution. This improvement not only enhances the computational efficiency of the model but also improves its generalization ability. The pro‐posed model is tested on three challenging public datasets, namely spleen, liver, and lung, from the medical segmentation decathlon. Experimental results show that the proposed model performance has in‐creased from 0.8315 to 0.8673, with a reduction in parameters of approximately 5%. This indicates that compared to currently advanced model structures, our proposed model architecture exhibits significant advantages in segmentation performance.
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