As a sovereign maritime country, Indonesia has been supported with patrol boats to maintain, protect, and manage the fishery and marine resources. Therefore, enhancing the patrol boat's operability is essentially needed for improving the resources maintenance and protection system. The implementation of an advanced hull forms might be conducted for the improvement of boat performance. The axe-bow hull form is one of the advanced hull forms that might improve the patrol boat operability, especially in high-speed conditions (Fr<0.60). However, in order to determine a reliable axe bow hull form, the body lines and the submerge bow depth should be defined appropriately. Based on the condition, this study focuses on the investigation of seakeeping performance of the developed axe-bow hull forms with variations of waterline spline type and submerged bow depth (the depth of foot). The waterline spline type configurations, which consist of the concave spline, convex spline, and straight spline, have been developed. At the same time, the submerged bow depths configuration have been proposed as 30%, 40%, and 50% of the boat draught. Both parameters should be recognized for the improvement of the axe bow hull seakeeping performance. The strip theory method has been adopted for the calculation of the seakeeping behavior. The results show that the waterline spline type has influenced the heave motion behavior. Otherwise, the larger depth of root might improve the pitch motion performance. It is indicated that suitable combination of spline type and depth of root might generate a reliable seakeeping performance of the axe-bow patrol boat.