Conventional Nonionic Surfactants Research Articles

Green synthesis and performance evaluation of mixed fatty acids-based esters as nonionic antifoaming biosurfactants

Three different polyethylene glycol (PEG) esters of 1:1 fatty acid mixture of ricinoleic, oleic, and linseed oil fatty acids, as eco-friendly nonionic antifoaming biosurfactants were synthesized using a solventless biocatalytic route, to overcome challenges associated with chemical processes. Immobilized lipase Candida antarctica (NS 435) was found to be more effective as a biocatalyst (10 % w/w) than Rhizomucor meihei (RMIM), and Thermomyces lanuginous (TLIM) and led to the highest percentage of fatty acid conversion ∼97.5–98.5 %. The reusability of lipase enzymes was studied, and it has been found that the catalytic activity of NS 435 lipase remained almost intact up to the ninth successive cycle and gradually reduced by 4–5 % thereafter. Whereas RMIM and TLIM were effective till 5 and 4 cycles respectively. The produced esters were characterized, evaluated, and compared for surface activity, emulsification, and antifoaming properties against commercially available nonionic surfactants. The results revealed that the synthesized PEG esters have higher thermal stability, better emulsifying, and excellent antifoaming properties than conventional nonionic surfactants. Thus, the synthesized PEG esters have shown great potential to be used as environment-friendly (>90 % biodegradability) nonionic antifoaming biosurfactants to prepare emulsifiable industrial fluids.

Impacts of several salts on the clouding development, nature of interactions and associated physico-chemical variables of mixture of promethazine hydrochloride and conventional nonionic surfactant

Herein, in the presence of electrolytes, the cloud points (CPs) of the mixture of a conventional uncharged amphiphile (triton X-100 (TX-100)) and promethazine hydrochloride (PMH; phenothiazine medicine) were measured and explained in great details. The CP values of the employed surfactant + PMH system were reduced with enhancing salts contents (NaCl, Na2SO4, NH4Cl, and (NH4)2SO4)), while the CP values of the study system followed the trend: Na2SO4 < NaCl and (NH4)2SO4 < NH4Cl. The different thermodynamic parameters of phase separation, including standard free energy (ΔG 0 c), enthalpy (ΔH 0 c), and entropy (ΔS 0 c) changes were also calculated and discussed elaborately. The values of free energy change (ΔG 0 c) were obtained to be positive, indicating that the clouding phenomena are non-spontaneous. Different transfer properties (free energy (ΔG 0 c.t), enthalpy (ΔH 0 c,t ), and entropy (ΔS 0 c,t ) of transfer), intrinsic enthalpy gain (ΔH 0,*c) and compensation temperature (T c) of the inspected system have also been assessed and discussed.

Amphiphilic Block Copolymers: Their Structures, and Self-Assembly to Polymeric Micelles and Polymersomes as Drug Delivery Vehicles.

Self-assembly of amphiphilic block copolymers display a multiplicity of nanoscale periodic patterns proposed as a dominant tool for the 'bottom-up' fabrication of nanomaterials with different levels of ordering. The present review article focuses on the recent updates to the self-association of amphiphilic block copolymers in aqueous media into varied core-shell morphologies. We briefly describe the block copolymers, their types, microdomain formation in bulk and micellization in selective solvents. We also discuss the characteristic features of block copolymers nanoaggregates viz., polymer micelles (PMs) and polymersomes. Amphiphilic block copolymers (with a variety of hydrophobic blocks and hydrophilic blocks; often polyethylene oxide) self-assemble in water to micelles/niosomes similar to conventional nonionic surfactants with high drug loading capacity. Double hydrophilic block copolymers (DHBCs) made of neutral block-neutral block or neutral block-charged block can transform one block to become hydrophobic under the influence of a stimulus (physical/chemical/biological), and thus induced amphiphilicity and display self-assembly are discussed. Different kinds of polymer micelles (viz. shell and core-cross-linked, core-shell-corona, schizophrenic, crew cut, Janus) are presented in detail. Updates on polymerization-induced self-assembly (PISA) and crystallization-driven self-assembly (CDSA) are also provided. Polyion complexes (PICs) and polyion complex micelles (PICMs) are discussed. Applications of these block copolymeric micelles and polymersomes as nanocarriers in drug delivery systems are described.

Metabolomics Response of Wheat (Triticum aestivum) to “Green” and Conventional Nonionic Surfactants at Different Application Stages

Metabolomics Response of Wheat (<i>Triticum aestivum</i>) to “Green” and Conventional Nonionic Surfactants at Different Application Stages

Modeling the shear-dependent viscosity of nonionically stabilized waterborne dispersions

The performance of a rheological model that accounts for the effect of the volume fraction, the particle size distribution, and shear rate on the viscosity of water-borne dispersions stabilized with conventional nonionic surfactants and polymeric stabilizers is assessed. The model that contains three parameters fitted well the experimental data. The parameters were independent of the volume fraction, the particle size distribution, and the shear rate. Furthermore, two of them were not affected by the surfactant type and concentration, and temperature. The other parameter increased with the surfactant molecular weight and surface covering, but decreased with increasing temperature.Graphical

PH- and thermo-responsive Pickering emulsion stabilized by silica nanoparticles and conventional nonionic copolymer surfactants

HypothesisPoly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) could be adsorbed on the silica surface via the hydrogen bonding between PEO and silanol (SiOH) groups. This interaction would be inhibited once SiOH is dissociated to SiO- at an increased pH value. Besides, the adsorption should be affected by temperature considering the nature of hydrogen bond. Hence, we speculate that silica nanoparticles modified in situ by adsorbed PEO-PPO-PEO possess a pH- and thermo-sensitive surface activity, making them a stimuli-responsive Pickering emulsifier. ExperimentsParaffin oil-in-water emulsions stabilized by silica nanoparticles and PEO-PPO-PEO were prepared. Stabilities, droplet morphologies and stimuli-responses were systematically studied using bottle test, optical microscopy and cryo-scanning electron microscopy (cryo-SEM). To clarify the emulsification mechanism, interfacial viscoelastic moduli and desorption energies were determined using the data obtained from drop shape analysis. FindingsSilica nanoparticles are hydrophobized and flocculated by adsorbed PEO-PPO-PEO at a relatively low pH and room temperature. Upon the pH or the temperature increased, particles regain their hydrophilicity and dispersity due to the desorption of surfactants. Emulsions stabilized by these surfactant-modified particles are pH- and thermo-responsive and can be repetitively switched between stabilization and destabilization. The switch temperature is controlled by the PEO length. The emulsification mechanism is verified in view of interfacial viscoelasticity and desorption energy. These findings demonstrate a novel and simple strategy of preparing pH- and thermo-responsive Pickering emulsions desirable to many industrial applications.

Structural Characterization of Nonionic Surfactant Micelles with CO2/Ethylene Oxide Head Groups and Their Temperature Dependence.

Using CO2 as a resource in the production of materials is a viable alternative to conventional, petroleum-based raw materials and therefore offers great potential for more sustainable chemistry. This study presents a detailed structural characterization of aggregates of nonionic dodecyl surfactants with different amounts of CO2 substituting ethylene oxide (EO) in the head group. The micellar structure was characterized as a function of concentration and temperature by dynamic and static light scattering and, in further detail, by small-angle neutron scattering (SANS). The influence of the CO2 unit in the hydrophilic EO group is systematically compared to the incorporation of propylene oxide (PO) and propiolactone (PL). The surfactants with carbonate groups in their head groups form ellipsoidal micelles in an aqueous solution similar to conventional nonionic surfactants, becoming bigger with increasing CO2 content. In contrast, the incorporation of PO units hardly alters the behavior, while the incorporation of a PL unit has an effect comparable to the CO2 unit. The analysis of the SANS data shows decreasing hydration with increasing CO2 and PL content. By increasing the temperature, a typical sphere-rod transition is observed, where CO2 surfactants show a much higher elongation with increasing temperature, which is correlated with the reduced cloud point and a lower extent of head group hydration. Our findings demonstrate that CO2-containing surface-active compounds are an interesting, potentially "greener" alternative to conventional nonionic surfactants.

Phase Studies and Efficient Recovery of Inorganic Metal Salts from the Microemulsion System Using a Sugar-Based Non-Ionic Surfactant

Abstract In the present work, the phase behaviour of the microemulsion system formulated by using water, organic solvent, and a sugar-based non-ionic surfactant was investigated in detail. We have used a sugar-based non-ionic surfactant for formulation of microemulsion, as it is a greener alternative for the formulation of a microemulsion system, owing to the following aspects: a) better physicochemical properties as compared to that of the conventional non-ionic surfactants, b) non-toxicity, and c) biodegradability. The extraction of heavy metal ions from the metal complexes as well as the recovery efficiency of heavy metal ions using a microemulsion system has been investigated. The maximum absorbance values of metal ions, after recovery from the metal complexes, were measured. Moreover, the UV-Visible spectrophotometric studies revealed that the absorbance increases with an increase in metal ion concentration in the aqueous phase while its value decreases with an increase in the concentration of potassium thiocyanate in the aqueous phase after the extraction of the metal ions from the metal complexes. Furthermore, it has also been evaluated that 4.0 mol/L potassium thiocyanate is the optimum concentration required for efficient recovery of 0.05 mol/L cobalt ion as well as nickel ions. The recovery efficiency of cobalt ions was found to be 97%, whereas that of nickel ions was determined to be 94% respectively. In addition to being an environmentally friendly approach, the present work is an economically viable option too, as it deals with the studies related to the extraction and efficient recovery of metal ions.

Conductivity, cloud point and molecular dynamics investigations of the interaction of surfactants with ciprofloxacin hydrochloride drug: Effect of electrolytes

Multiple methods (conductivity, cloud point (CP), and molecular dynamics simulation) were applied to evaluate the interaction of tetradecyltrimethylammonium bromide (TTAB) and Tween 80 (Tw 80) with ciprofloxacin hydrochloride (CFH) in electrolytes solution. From the phase separation technique, values of cloud point (CP) of Tw 80 + CFH mixture were evaluated and noticed to decrease through the increase of CFH content. The free energy of clouding (∆Gco) values of Tw 80 + CFH mixture were noticed as positive in whole cases which indicates the non-spontaneity of the clouding phenomenon. Other thermodynamic properties and thermodynamic parameters of transfer for Tw 80 + CFH mixture in salts media were also evaluated and explained in detail. From conductivity measurements, micellar parameters-critical micelle concentration (cmc), the fraction of counterion dissociation (ɑ), and thermodynamic parameters of the studied systems have been evaluated. The cmc values were found to be dependent on the temperature and concentration of salt. In salt solution (NaCl), the cmc values of TTAB+CFH mixtures decrease with enhancing NaCl concentration viewing the start of micelle formation at inferior TTAB concentration. The values of ∆Hmo as well as ∆Smo prove the presence of hydrophobic and electrostatic interaction between drug and surfactant. Herein, the molecular dynamics simulation method was also taken into consideration in exposing the mechanism of CFH-surfactants interactions happening at the atomic level, which exposed a good comparison with the experimental outcomes. Herein, the obtained results implied that conventional nonionic surfactant may possibly work as a efficient drug delivery vehicle for antibiotics, enhancing their bioavailability.

Synergistic Solubilization of Phenanthrene by Mixed Micelles Composed of Biosurfactants and a Conventional Non-Ionic Surfactant

This study investigated the solubilization capabilities of rhamnolipids biosurfactant and synthetic surfactant mixtures for the application of a mixed surfactant in surfactant-enhanced remediation. The mass ratios between Triton X-100 and rhamnolipids were set at 1:0, 9:1, 3:1, 1:1, 1:3, and 0:1. The ideal critical micelle concentration values of the Triton X-100/rhamnolipids mixture system were higher than that of the theoretical predicted value suggesting the existence of interactions between the two surfactants. Solubilization capabilities were quantified in term of weight solubilization ratio and micellar-water partition coefficient. The highest value of the weight solubilization ratio was detected in the treatment where only Triton X-100 was used. This ratio decreased with the increase in the mass of rhamnolipids in the mixed surfactant systems. The parameters of the interaction between surfactants and the micellar mole fraction in the mixed system have been determined. The factors that influence phenanthrene solubilization, such as pH, ionic strength, and acetic acid concentration have been discussed in the paper. The aqueous solubility of phenanthrene increased linearly with the total surfactant concentration in all treatments. The mixed rhamnolipids and synthetic surfactants showed synergistic behavior and enhanced the solubilization capabilities of the mixture, which would extend the rhamnolipids application.

Surfactant/biosurfactant mixing: Adsorption of saponin/nonionic surfactant mixtures at the air-water interface

Saponins are naturally occurring biosurfactants present in a wide range of plant species. They are highly surface active glycosides, and are used to stabilise foams and emulsions in foods, beverages and cosmetics. They have great potential for an even wider range of applications, especially when mixed with different synthetic surfactants. Understanding those mixing properties are key to the exploitation of saponins in that wider range of potential applications.The surface adsorption properties of the saponin, escin, with two conventional nonionic surfactants, polyethylene glycol surfactants, have been studied at the air-water interface using neutron reflectivity, NR, and surface tension, ST.Although the saponin and polyethylene glycol, CnEOm, surfactants are both nonionic the disparity in the relative surface activities and packing constraints result in non-ideal mixing. Comparison with the predictions of the pseudo phase approximation requires the inclusion of the quadratic, cubic and quartic terms in the expansion of the excess free energy of mixing to explain the variations in the surface composition. For escin/pentaethylene glycol monododecyl ether, C12EO5, the interaction is attractive and close to ideal. For escin/octaethylene glycol monododecyl ether, C12EO8, it is repulsive and close to the criteria for demixing. The differences in mixing behaviour are attributed to greater packing constraints imposed by the larger ethylene oxide headgroup of the C12EO8 compared to C12EO5.

Phase behavior and microstructure of sugar surfactant-ionic liquid microemulsions

Microemulsions have been explored as a unique and versatile reaction media for a variety of chemical reactions, viz. nanoparticle preparation, organic synthesis, bio-organic synthesis etc. The phase behavior and microstructure of a ternary system water/1-butyl-3-methylimidazolium hexafluorophosphate/Sugar Surfactant was studied as a function of temperature and sugar surfactant mass fraction, γ. In the present study, a hydrophobic ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate was used to replace commonly used organic solvents (n-alkanes) as an oil/non-polar phase substitute in ternary microemulsion formulations, wherein, a sugar based alkyl polyglycoside nonionic surfactant was used instead of a conventional nonionic surfactant (i.e., alkyl polyoxyethylene ether class) to solubilize hydrophobic ionic liquid and water. The effect of alkanols of variable chain length (octanol, decanol and dodecanol) as co-surfactant on the phase behavior and microstructure of ionic liquid/sugar surfactant/water ternary microemulsion systems was also investigated. The ability of nonionic sugar-based surfactant n-decyl β-D-maltoside, and n-dodecyl β-D-maltoside, to solubilize oil (hydrophobic ionic liquid) and water, i.e., was evaluated. Moreover, phase behavior and microstructure of ternary systems, 1-butyl-3-methylimidazolium tetrafluoroborate:water (1:1)/sugar surfactant/n-alkanes (alkanes of varying chain length, i.e., octane, decane and dodecane) was also studied. Solubilization of a water insoluble dye, Sudan Red, in selected microemulsion systems was also investigated.

The dynamics of surface adsorption and foam formation of carbonate modified nonionic surfactants

For a group of nonionic surfactants with polar head groups synthesized by copolymerization of ethylene oxide and carbon dioxide, the adsorption dynamics at the water-air surface were investigated by dynamic surface tension measurements using the maximum bubble pressure technique. From the apparent diffusion coefficients at different concentrations, the diffusion coefficients of surfactant monomers and micelles were deduced and compared to conventional nonionic surfactants. These transport properties were correlated with results from foamability studies in Bartsch tests as well as sparging tests. The obtained foam volumes show a good correlation with the diffusion coefficients of the surfactant monomers multiplied with the concentration of available monomers, the cmc. The same relation is found for the foam stability, expressed in the foam half lifetime. The correlations show for surfactant solutions well above the critical micelle concentration that the transport of surfactant monomers to the interface rather than the micelles is the essential step in both, the foam formation as well as the foam stabilization, following a simple Fickian diffusion law.

From interface towards organised network: Questioning the role of the droplets arrangements in macroscopically stable O/W emulsions composed of a conventional non-ionic surfactant, TiO2 particles, or their mixture

This study focused on the formulation and the analysis of three emulsions stabilised by TiO2 particles (TiO210), by a conventional Steareth-2/21 surfactant (St10) and by the mixture of both (TiO25St5). Each system efficiently stabilised the oil/water interface and formed macroscopically stable and totally emulsified oil in water formulations.According to microscopic observations, Steareth emulsifier formed a well-organised network of small and monodispersed oil droplets, while the mixture (TiO25St5) favoured the polydispersity and bigger droplet sizes. Finally, the TiO2 stabilised emulsion showed a high droplet polydispersity and the presence of flocculated particles in the continuous phase.The type of emulsifying system also had an impact on droplets interaction and organisation. Oscillatory and continuous rheological tests, as well as thermal analysis, showed the Steareth-2/21 capacities to assure the stability through both: oil/water interface stabilisation and development of strongly connected and resistant droplet organisation. The analysis of TiO2/Steareth emulsion interestingly pointed out the Steareth main role in the stabilisation processes with specific properties like resistance to deformation. Meanwhile, the emulsion stabilised exclusively by TiO2 particles showed unique viscoelastic behaviour: the particles are forming an elastic emulsion at rest, but the droplet network being fragile is quickly disrupted under the solicitation.The applicative properties of the systems were studied through the textural approach (compression, extrusion, spreading and stretching tests) and confirmed the rheological results. For small solicitations, with partial destruction of the matrix, the 3D networks formed by the high presence of the Steareth-2/21 molecules (St10) are quite similar to the networks created by the flocculated TiO2 particles in the continuous phase of the emulsion (TiO210). However, their behaviour does not evolve in the same manner. Once the solicitation increases, the particles stabilised emulsion will break down, while the Steareth-2/21 containing ones will be more flexible and adaptive.

Imidazolium-based ionic liquid surfactants as pseudostationary in combination with a chiral selector in micellar electrokinetic chromatography.

In recent years, ionic liquid-based surfactants have drawn more and more attention. As a new promising brand of surfactants, ionic liquid-based surfactants have their unique properties and superior aggregation behavior, which can be introduced as micellar pseudostationary in MEKC mode. In this paper, a novel ionic liquid-based surfactant, 1-butyl-3-methylimidazolum dodecyl sulfate [C4MIm][C12SO4], was synthesized through ion exchange reaction and applied for the first time to form micellar as pseudostationary phase for chiral separation with clindamycin phosphate as chiral selector. As observed, compared with conventional non-ionic liquid anionic surfactant, improved separation of tested drug enantiomers was obtained in the established MEKC system with ionic liquid-based surfactant. Parameters such as concentration of ionic liquid-based surfactants, type and proportion of organic modifier, concentration of chiral selector, and pH of buffer solution were systematically investigated to optimize the ionic liquid-based surfactant MEKC system. Graphical abstract.

Synthesis and properties of dihydroxyoleic acid methyl ester ethoxylates

In this paper, epoxy methyl oleate (EMO) was used as the raw material to obtain the dihydroxyoleic acid methyl ester (DHOME) through ring-opening reaction. Then, the DHOME was reacted with ethylene oxide (EO) under Al-Mg composite oxide catalyst to synthesize a novel nonionic surfactant: dihydroxyoleic acid methyl ester ethoxylate (DHOMEE), which has both alcohol polyether and ester polyether chains. FT-IR was used to characterize the molecular structure of target product. Products with different EO addenda (DHOMEE-10, DHOMEE-15, DHOMEE-20) and conventional nonionic surfactants fatty acid methyl ester ethoxylate (FMEE) and methyl oleate ethoxylate (OMEE) were compared in terms of application performance. The results showed that DHOMEE is superior to conventional surfactants in terms of wetting, emulsification, foam and surface tension. In similar products, the performance of DHOMEE-15 is better than those of DHOMEE-10 and DHOMEE-20.

Solubility Enhancement of Polycyclic Aromatic Hydrocarbons by an Eco-Friendly Ester-Linked Gemini Surfactant and its Mixtures with Conventional Surfactants

AbstractThe present study deals with the solubility enhancement of the two polycyclic aromatic hydrocarbons (PAHs) anthracene and pyrene in the aqueous micellar system of the cationic ester-containing cleavable gemini surfactant ethane-1,2-diyl-bis(N,N-dimethyl-N-tetradecylammoniumacetoxy) dichloride (14-E2-14 = C14H29(CH3)2N+(CH2COOCH2)2N+(CH3)2C14H29 · 2Cl−)), and its equimolar binary mixtures with some typical conventional cationic, anionic and non-ionic surfactants. The surface tension and conductivity measurements were used to evaluate the physicochemical parameters such as the critical micelle concentration (CMC), the interaction parameter (βm) and Gibbs excess free energy of micellization (ΔGexm) of the systems. The extent of solubilization of the micellar systems towards PAHs has been quantified in terms of molar solublization ratio (MSR), micellar/water partition coefficient (ln Km) and the standard Gibbs free energy of solubilization (ΔGs0). Above the CMC, all studied single as well as binary gemini-conventional surfactant systems show an increase in solubilization of the PAHs. For pure systems, the MSR value of Brij 58 was found to be significantly higher than that of the other amphiphiles. Amongst the mixed surfactant systems, the solubility enhancement of anthracene is found to be maximum in the 14-E2-14 + SDS/SDBS system whereas the system14-E2-14 + Brij 58 shows a higher solubility for pyrene.

SBA-15/Metformin as a novel sorbent combined with surfactant-assisted dispersive liquid–liquid microextraction (SA-DLLME) for highly sensitive determination of Pb, Cd and Ni in food and environmental samples

This paper established a new, rapid and sensitive method for the ultra-trace determination of lead, cadmium and nickel in food and environmental samples preconcentrated by dispersive solid-phase extraction (DSPE) combined with surfactant-assisted dispersive liquid–liquid microextraction (SA-DLLME) prior to graphite furnace atomic absorption spectrometry. SBA-15/Met was synthesized and used as a new efficient sorbent for the extraction of metal ions in DSPE. It was characterized by TEM and TGA techniques. After DSPE step, stripped metal elements were complexed with dithizone, and then, the complexes were extracted into carbon tetrachloride by using SA-DLLME. A conventional nonionic surfactant, triton X-100 was used as a disperser agent. Under the optimized conditions, the limit of quantifications was found to be 2.5 ng L−1 for Pb2+, Cd2+ and 5.0 ng L−1 for Ni2+. The limits of detection were 1.5 ng L−1 for Ni2+ and 0.75 ng L−1 for Pb2+ and Cd2+, with enrichment factor of 1650. The optimized method exhibited a good precision level with relative standard deviations (RSDs%) values of 4.9, 5.2 and 5.0% for 1 μg L−1 Pb2+, Cd2+ and Ni2+, respectively (n = 7). Application of the proposed method to the analysis of fish-certified reference material produced results that were in good agreement with the certified values.

Synthesis and properties of α-sulfo carboxyl disodium salt

ABSTRACTThe synthesis and properties of α-sulfo carboxyl disodium salt (SCDS) were studied in detail for the first time in this paper. SCDS was synthesized via saponification reaction of fatty acid methyl ester sulfonate sodium (MES). FT-IR was used to characterize the molecular structure of target product. The yield of disodium salt was greater than 98% by two-phase titration. The performance of SCDS was studied and was compared with raw materials MES, conventional anionic surfactant AES and nonionic surfactant AEO9. The result shows SCDS can reduce the surface tension of the solution to 27.89 mN/m at critical micelle concentration (CMC). The wetting ability of SCDS was significantly enhanced with the increase of temperature. The emulsification effect of SCDS on the soybean oil is better than that on the liquid paraffin. Surprisingly, SCDS has a good foamability and foaming stability.

One-step synthesis, wettability and foaming properties of high-performance non-ionic hydro-fluorocarbon hybrid surfactants

Abstract In this work, a series of non-ionic hydro-fluorocarbon hybrid surfactants (C 9 F 19 CONH(CH 2 ) 3 N(C m H 2m+1 ) 2 , abbreviated as C 9 F 19 AM (m = 1), C 9 F 19 AE (m = 2) and C 9 F 19 AB (m = 4) were easily synthesized by one-step reaction and characterized by 1 HNMR, 19 FNMR and MS spectroscopy. Unlike conventional non-ionic surfactants (most hydrophilic units consisted of hydroxy or ether groups), their hydrophilic groups were composed of amide group, an eco-friendly unit. The surface activity, wettability, thermal stability and foaming performance were investigated. The results showed that the C 9 F 19 AE (C 9 F 19 CONH(CH 2 ) 3 N[CH 2 CH 3 ] 2 ) had superior surface and interface activities, which could reduce the surface tension of water down to 15.37 mN/m and the interfacial tension (cyclohexane/water/surfactants) to 5.8 mN/m with a low cmc (critical micelle concentration) of 0.12 mmol/L. Through the calculation of A min (the minimum area occupied per-surfactant molecule), we speculated this higher surface activity was related to the compatibility between hydrocarbon and fluorocarbon chains. When used as wetting and foaming agents, the C 9 F 19 AE also outperformed great advantages over conventional non-ionic fluorocarbon and hydrocarbon surfactants, which could decrease the contact angle of water on PTFE plate from 107.7° to 3.6°, and increase the foam integrated value F to 536 500 ± 3066.5 mL s. Moreover, the decomposition temperature (T d ) of C 9 F 19 AE could reach up to 173 °C. This work demonstrates a valuable strategy to develop a kind of high-efficiency foaming agent via facile synthesis.