This work aims to develop a generalizable framework for control structure selection using process operability analysis. Current approaches for selecting controlled variables in chemical processes are limited to assessing system attributes individually, focusing on controller performance or the economic impact based on a constant setpoint policy. However, the competitive industrial manufacturing market requires a holistic approach for control structure selection in large-scale plants that takes into account multiple factors. In particular, process operability can help to enable a generalizable approach that is able to select control structures that are operable considering economic and performance factors simultaneously. To achieve this goal, a framework that uses the Operability Index (OI) as a metric for ranking the achievability of the control objectives for the selected control structures is developed. To test the framework, a depropanizer distillation column is investigated as a case study associated with large-scale energy systems. This work thus introduces novel formulations and algorithms for the control structure selection problem, enhancing the design, operations, and synthesis of existing and future industrial systems.
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