Contribution Of Reactive Species Research Articles

Enhancing the Photocatalytic Performance for Norfloxacin Degradation by Fabricating S-Scheme ZnO/BiOCl Heterojunction

Construction of S-scheme heterojunctions can effectively limit the recombination of photogenerated e− and h+, thus improving photocatalytic activity. Therefore, S-scheme ZnO/BiOCl (molar ratio = 1:2) n–n heterojunctions were synthesized via a hydrothermal–hydrolysis combined method in this study. The physical and chemical properties of the ZnO/BiOCl heterojunctions were characterized by XRD, XPS, SEM, TEM, DRS, N2 adsorption–desorption and ESR. Additionally, the photoelectric performances of ZnO/BiOCl heterojunctions were investigated with TPR, M–S plot and EIS. The results show that photocatalytic degradation of NOR by ZnO/BiOCl reached to 94.4% under simulated sunlight, which was 3.7 and 1.6 times greater than that of ZnO and BiOCl, respectively. The enhanced photodegradation ability was attributed to the enhancement of the internal electric field between ZnO and BiOCl, facilitating the active separation of photogenerated electrons and holes. The radical capture experiments and ESR results illustrate that the contribution of reactive species was in descending order of ·OH > h+ > ·O2− and a possible mechanism for the photodegradation of NOR over S-scheme ZnO/BiOCl heterojunctions was proposed.

Structural dependent degradation of histamine H2-receptor antagonists by UV/NH2Cl: Reactive species contribution and the role of carbonate ions on ·NO generation

Histamine H2-receptor antagonists (HRAs) are a group of widely used gastrointestinal drugs that have been frequently detected in natural environments. UV/chloramine (NH2Cl) is a widely used disinfection process in water treatment, while the performance of HRAs degradation by UV/NH2Cl is still unclear. In this work, the degradation kinetics, mechanism and disinfection byproducts formation of HRAs by UV/NH2Cl were studied. The degradation of HRAs, including ranitidine (RNTD), nizatidine (NZTD), roxatidine (RXTD), cimetidine (CMTD) and famotidine (FMTD) was fast in the UV/NH2Cl process, and ·OH, Cl· and ·NO contributed to their degradation. CMTD had the highest rate constants with ·OH, Cl· and ·NO. RXTD, NZTD and FMTD were more reactive with ·OH, while RNTD was more selective towards Cl·. The contribution of ·OH, Cl· and reactive nitrogen species to HRAs degradation in water matrices was further quantified by kinetic modeling. Interestingly, carbonate species were found to promote the yield of ·NO. Further investigation through sensitivity analysis of the modeling reactions concluded the sensitive reactions for ·NO promotion. The structure–activity assessment domenstrated that the reactivity of thioether sulfur, CMTD-C3 and RXTD-N48 and piperidine rings resulted in the difference of degradation rates. Hydroxylation, nitrosation, chlorine substitution and oxygen atom transfer were the primary pathways for HRAs degradation. The formation of NDMA might be a prevalent problem along HRAs’ degradation in the UV/NH2Cl process, and the formation potential of NDMA is dependent on the types of amine groups in HRAs. This work provides an effective strategy to eliminate HRAs, revealed the NDMA formation potential in HRAs, and emphasized the role of carbonate species in ·NO generation.

Ultrasound-enhanced peracetic acid oxidation improves short-chain fatty acids production from waste activated sludge

This study proposed a new technology, i.e., ultrasound (US)-enhanced peracetic acid (PAA) pretreatment, to enhance resource recovery from anaerobic sludge fermentation. Results show that the optimum operation condition was achieved with US-enhanced 10 mg PAA/g TSS (total suspended solids), leading to a remarkable 31.72-fold increase in short-chain fatty acids (SCFAs) production compared to the control group (with PAA contribution in SCFAs deducted). Mechanism explorations prove that US-enhanced PAA pretreatment significantly promoted sludge disruption and organic matter release, creating a substantial amount of soluble substances (i.e., tyrosine-like and tryptophan-like substances) for subsequent fermentation. Fourier transform infrared (FTIR) analysis indicates that US-enhanced PAA pretreatment induced alterations in the protein secondary structure and facilitated its transformation. Quenching experiments imply that the contribution of reactive species during sludge oxidation followed the order: 1O2 >OH > CH3C(O)O/CH3C(O)OO. These reactive species played essential roles in the inherent mechanisms responsible for sludge disintegration and organic conversion. On the other hand, the analysis of key enzyme activities reveals a severe inhibition of the enzymes associated with SCFAs consumption. Further microbial community investigation confirms the enrichment of acidogenic microorganisms, such as Clostridium_sensu_stricto_10 sp., norank_f__norank_o__Bacteroidales sp., etc. Overall, US-enhanced PAA pretreatment can facilitate energy recovery and enhance the efficiency of anaerobic fermentation, offering significant benefits in sustainable sludge management.

Peracetic acid combined with ultraviolet for ibuprofen degradation: Activation mechanism and reactive species contribution

As an emerging advanced oxidation technology, ultraviolet/peracetic acid (UV/PAA) shows great potential in removing pharmaceuticals and personal care products (PPCPs) in the field of wastewater treatment. In this work, ibuprofen (IBP) was chosen as the contaminant to study the degradation effects and PAA activation mechanisms by UV irradiation. The experimental results showed that UV/PAA had an excellent degradation efficiency (99.22 %) of IBP after 15 min reaction, and the synergistic effect between UV and PAA was also observed. Increasing the dosage of PAA caused the increase in IBP degradation reaction rate. Under acidic conditions, the increase in pH values increased the degradation reaction rate, whereas the opposite was true in alkaline conditions. In addition, the coexisting substrates (e.g., NO3-, CO32-, Ca2+, and HA) could exert inhibition on the degradation. Quenching experiments were carried out using various quenchers to identify reactive oxygen species (ROSs) in the system. The results demonstrated that ·OH and carbon centered radicals (R-C·) played a dominant part in the degradation, and the contribution of CH3C(O)OO·,·O2-, CH3C(O)O·, ·OH, and direct photolysis were estimated to be 29.9 %, 26.9 %, 21.5 %, 14.5 %, and 7.2 %, respectively. The results of IBP intermediates identification indicated that the degradation process was mainly related to its side chain decarboxylation, oxidative dehydrogenation, demethylation, and the oxidation of the aromatic ring. Furthermore, Toxicity Estimation Software Tool (T.E.S.T.) and ECOSAR were applied to evaluate the toxicity of the intermediate products was further evaluated. This study enriched the understanding of the PAA activation mechanism by UV involved, and improved the theory and technology of removing PPCPs by UV/PAA process.

Accelerating Fe2+/Fe3+ cycle via biochar to improve catalytic degradation efficiency of the Fe3+/persulfate oxidation

The sluggish Fe3+/Fe2+ cycle was the rate-limiting step in the Fenton-like reaction, and metal-free carbonaceous materials are considered as emerging alternatives to solve this problem. However, the effect of carbon material properties on the distribution of reactive species remains poorly understood. This study investigated the possibility and mechanism of using biochar to accelerate the Fe3+/Fe2+ cycle to overcome the low efficiency of Fe3+/persulfate (PS) catalytic oxidation of phenanthrene. More importantly, the contribution of reactive species in the reaction systems with the variation of biochar pyrolysis temperatures was quantitatively studied. The results showed that medium-temperature derived biochar (BC500) had the greatest ability to enhance the Fenton-like system compared to the low- and high-temperature (BC350/700), and the first-order rate constant achieved 5.2 and 35.7-fold increase against the biochar/PS and Fe3+/PS systems, respectively. Using electrochemical evidence, sulfoxide probe tests, and steady-state concentration calculations, radicals yields were found to rise and then reduce with decreasing pyrolysis temperature, while the nonradical contribution of Fe(IV) increased to 56.3%. Electron paramagnetic resonance, Boehm titration, and Raman spectroscopy unraveled that the enhanced effect of biochar resulted from itself persistent free radicals, phenolic-OH, and edge defects, which enabled electron transfer between Fe3+ and biochar. Fe2+ was thus continuously generated and effectively activated the PS. This work enables a better understanding of the Fe3+-mediated Fenton-like reaction in the presence of biochar and provides a sustainable green strategy for Fenton chemistry with potential applications.

Highly efficient azo dye degradation in a photocatalytic rotating disc reactor with deposited l-histidine-TiO2-CdS

In the past few years, the quest for visible light active TiO2-based photocatalysts has been a hotly debated research topic in both scientific and practical fields. Attempting to meet the same purpose, in this study, a visible-driven nanocomposite, l-Histidine (2 wt%)-TiO2-CdS (7:1) nanocomposite, was dip-coated on the glass disc (rough vs. smooth) after the optimum composition was identified by varying the l-Histidine and CdS quantities. The prepared nanoparticles and coated catalyst on the disc were characterized by XRD, FT-IR, X-ray (FE-SEM/EDX), DRS, PL analyses in terms of their structural and optical properties as well as morphology. The coated photocatalyst was tested for photocatalytic degradation of direct red 16 (DR16) as an azo dye. The photodegradation process variables, including disc rotation speed, light intensity, irradiation time, and type of disc (smooth vs. rough glass disc)) were also modeled and optimized by central composite design (CCD). At the optimum conditions obtained, the effects of reaction time, pH, DR16 concentration, and aeration were investigated. After 3 h of using the rough disc (disc II) at a disc rotation speed of 100 rpm as well as a light intensity of 13 lumens per m2, DR16 was completely degraded. The pH and DR16 concentration seemed to have the reverse impact on the photodegradation process, whereas aeration had such a positive effect. By analyzing the effects of various scavengers, the contribution of reactive species in the photodegradation process was thoroughly investigated. Furthermore, the reusability results indicate no significant change in the photodegradation efficiency after four cycles.

New insights into the degradation of micro-pollutants in the hydroxylamine enhanced Fe(II)/peracetic acid process: Contribution of reactive species and effects of pH

The hydroxylamine-enhanced Fe(II)/peracetic acid (PAA) process is a promising advanced oxidation process (AOP) with the generation of reactive species (RS) including RO•, •OH and Fe(IV). Nevertheless, it is still challenging to identify which RS is the major intermediate oxidant, and the reasons why the optimal condition is pH 4.5 rather than 3.0 are also unclear. Herein, the generation of RS and their contribution to the degradation of three micro-pollutants were explored. The quenching experiments and pseudo first-order kinetic model demonstrated that RO• rather than the other two RS were predominant. Then the overall generation and evolution pathways of RS were depicted. The elevation of pH (3.0–4.5) would accelerate the Fe(II)/Fe(III) redox cycle through the enhanced reduction of Fe(III) by hydroxylamine and induce the conversion of Fe(IV) to RO•, which benefited naproxen degradation. While the adverse Fe(III) precipitation would dominate the reduced degradation performance with the solution pH higher than 4.5. The elevation of PAA and Fe(II) dosages sped up the PAA activation, while excess hydroxylamine could consume the formed RS and exhibited an inhibitory effect. This study helps further understand the role of HA and differentiate the contribution of RS in the emerging PAA-based AOPs.

Metal organic framework-derived Zr/Cu bimetallic photocatalyst for the degradation of tetracycline and organic dyes

The exploitation of tetracycline antibiotics (TCs) has caused significant hazards to both the humans as well as the environment. As a result, developing efficient strategies to eliminate these contaminants is both important and practicable. Photocatalytic degradation appears to be one of the most potential techniques for extracting antibiotics. Semiconductors seem to be the most extensively used photocatalysts even though their performance is still hampered by light absorption limitations and poor charge separation. MOFs are worthy choices for the construction of hierarchical nanostructures with semiconductors to address the foregoing concerns because of their extraordinary features including better surface area and extensive active sites. Zr/Cu-MOF was synthesised by precipitation refluxing method and its efficacy as a photocatalyst for the degradation of TC antibiotics and poisonous dyes such as rhodamine B and methylene blue was examined in this study. The Zr/Cu-MOF displayed excellent efficacy for degradation of tetracycline (93 % in 80 min), Rhodamine B (96 % in 70 min) and methylene blue (96 % in 50 min) with rate constant of 0.0308, 0.052 and 0.068 min−1. The contribution of reactive species in antibiotics and dye degradation was confirmed by radical scavenging investigations which showed that.OH radical has a significant role in photocatalytic decomposition. In addition, tests using liquid chromatography-mass spectrometry (LC-MS) were carried out in order to predict a probable mechanism for TC degradation.

Elimination of micropollutants by the solar/chlorine process: contribution of reactive species and formation risk of NDMA

Role of reactive species in the solar/chlorine process for elimination of diuron and risk of NDMA formation.

An anaerobic-applicable Bi2MoO6/CuS heterojunction modified photocatalytic membrane for biofouling control in anammox MBRs: generation and contribution of reactive species

The anaerobic (anoxic) environment in anaerobic membrane bioreactors (AnMBRs) largely limits the antifouling application of aerobic-applicable photocatalysts, calling for preparation of anaerobic-applicable photocatalytic membranes, and exploration of generation and contribution mechanisms of reactive species under anaerobic (anoxic) condition. Herein, novel visible-light photocatalytic membranes (B2) were prepared by modifying pristine membranes (B0) with hollow flower-like Bi2MoO6/CuS heterojunctions to explore production and antifouling function of reactive species in anammox MBRs. During 157-d operation under waterproof lights irradiation, the average fouling cycle of B2 extended to 228.5% of B0, while their total nitrogen removal efficiencies (TNRE) were comparable and maintained at 0.85–0.9. The energy against the membrane fouling resistance were saved about 18.4% by filtering with B2. By adding scavengers of reactive species in flux recovery tests, photocatalytic generated ·OH, h+ and e− were testified to be responsible for the alleviated membrane fouling, whereas ·OH (rather than ·O2−) was qualitatively and quantitatively proved to be the key reactive oxygen species produced by B2. Compared with B0, the degradation and inactivation capabilities of reactive species on B2 brought about 47.7% lower organic foulant by decomposing protein, polysaccharide and lipid; and contributed to 76.1% lower total bacteria, 51.0% higher necrotic cells, and 29.1% higher esterase-inactivated cells. Furthermore, the photocatalytic membranes showed satisfactory stability and biocompatibility, providing powerful support for their long-term usage in MBRs as a low-carbon and eco-friendly strategy. The systematic insights into reactive species contribution for fouling alleviation by the anaerobic-applicable photocatalytic membrane offer valuable instructions for extended antifouling application of photocatalysis in AnMBRs.

Removal of sulfamethoxazole by ferrous iron activation of persulfate: Optimization of dosing strategy and degradation mechanism

In this paper, the degradation of sulfamethoxazole (SMX) was investigated using the ferrous iron (Fe2+) activation of persulfate (PS) (the Fe2+/PS process). The influence of the initial concentration of both PS and Fe2+ was investigated. It was found that increasing the PS concentration resulted in a higher SMX degradation efficiency. The influence of inhibiting reactions was found to increase with increasing Fe2+ concentration. In order to minimize these inhibiting reactions, different dosing strategies were applied. It was found that the SMX degradation efficiency could be enhanced significantly when changing from direct dosing (total amount of Fe2+ dosed at the start) to sequential dosing (dosing that same total amount but divided over specific time intervals) and even more when using continuous dosing (dosing the same total amount but continuously over 30 min reaction time). The contribution of different reactive species in this process was also investigated. It was found that hydroxyl radicals (•OH) were mainly responsible for the degradation of SMX during direct dosing, while using continuous dosing of Fe2+, the contribution of Fe(IV) and sulfate radicals (•SO4-) became more important (reduction of •OH contribution from 89 to 71%). Some degradation products formed during the SMX degradation process were identified and the difference in reaction mechanism between •OH on the one hand and Fe(IV) and •SO4- on the other hand was elucidated. At last, a comparison of different sulfate radical based advanced oxidation processes (SR-AOP) is performed by comparing the difference in SMX degradation efficiency, reactive species contribution and the formed degradation products. In most investigated processes, similar degradation products have been found, however, the large •OH contribution in the Fe2+/PS process resulted in distinct degradation products.

Nanostructured LaFeO3-MoS2 for efficient photodegradation and photocatalytic hydrogen evolution

Fabrication of heterogeneous photocatalysts has received increasing research interest due to their potential applications for the degradation of organic pollutants in wastewater and evolution of carbon-free hydrogen fuel via water splitting. Here, we report the photodegradation and photocatalytic hydrogen generation abilities of nanostructured LaFeO3-MoS2 photocatalyst synthesized by facile hydrothermal technique. Prior to conducting photocatalytic experiments, structural, morphological and optical properties of the nanocomposite were extensively investigated using X-ray diffraction analysis, field emission scanning electron microscopy and UV-visible spectroscopy, respectively. Nanostructured LaFeO3-MoS2 photodegraded ~96% of rhodamine B dye within only 150 minutes which is considerably higher than that of LaFeO3 and commercial Degussa P25 titania nanoparticles. The LaFeO3-MoS2 nanocomposite also exhibited significantly enhanced photocatalytic efficiency in the decomposition of a colorless probe pollutant, ciprofloxacin eliminating the possibility of the dye-sensitization effect. Moreover, LaFeO3-MoS2 demonstrated superior photocatalytic activity towards solar hydrogen evolution via water splitting. Considering the band structures and contribution of reactive species, a direct Z-scheme photocatalytic mechanism is proposed to rationalize the superior photocatalytic behavior of LaFeO3-MoS2 nanocomposite.

Highly efficient AgBr/h-MoO3 with charge separation tuning for photocatalytic degradation of trimethoprim: Mechanism insight and toxicity assessment

A highly solar active AgBr/h-MoO3 composite was constructed by a facile precipitation method, and the charge separation tuning was achieved by photoreduction of AgBr. The photoreduced Ag0 on AgBr/h-MoO3 acted as charge transfer bridge to form Z-scheme heterostructure, while the high degree of Ag reduction converted the material into type-II heterostructure. The synthesized optimal material promoted charge separation and visible light activity due to the incorporation of highly solar active AgBr, which showed ca. 2 times activity on trimethoprim (TMP) degradation than h-MoO3. The contribution of reactive species on TMP degradation followed the order of O2− >1O2 > h+, which agree well with the proposed charge separation mechanism. The photocatalytic degradation mechanism of TMP was proposed based on the radical quenching, intermediate analysis and DFT calculation. The toxicity analysis based on QSAR calculation showed that part of the degradation intermediates are more toxic than TMP, thus sufficient mineralization are required to eliminate the potential risks of treated water. Moreover, the material showed high stability and activity after four reusing cycles, and it is applicable to treat contaminants in various water matrix. This work is expected to provide new insight into the charge separation tuning mechanism for the AgX based heterojunction, and rational design of highly efficient photocatalysts for organic contaminants degradation by solar irradiation.

Surface modification of BiOBr/TiO2 by reduced AgBr for solar-driven PAHs degradation: Mechanism insight and application assessment

A novel solar active AgBr/BiOBr/TiO2 catalyst was synthesized by a facile coprecipitation method for solar-driven water remediation. The synthesized material composed of flower-like TiO2 nanoparticles loaded on BiOBr nanosheets and with homogeneous surface distributed Ag/AgBr nanoparticles. The internal electric field between BiOBr/TiO2 heterojunction greatly facilitated the charge carrier migration; the introduction of narrow band gap semiconductors (AgBr and BiOBr) promoted the visible light adsorption; and the Ag/AgBr nanoparticles acted as photosensitizer to further improve the light utilization. The new material showed 7.6- and 4.0-times activity of pure TiO2 and BiOBr under solar light, and the contribution of reactive species on anthracene degradation followed the order of h+ >O2•−> •OH. The degradation mechanism and pathway were proposed based on intermediates analysis and DFT calculation. The QSAR analysis revealed that the environmental risks of contaminants were greatly reduced during the photocatalysis process but some intermediates were still toxic. The high photocatalytic activity, stability and adaptability all indicated that this new material owns great application potential for cost-effective photocatalytic remediation of persistent organic contaminants under solar light.

Degradation of clofibric acid in UV/chlorine disinfection process: kinetics, reactive species contribution and pathways.

As a potential endocrine disruptor, clofibric acid (CA) was investigated in this study for its degradation kinetics and pathways in UV/chlorine process. The results showed that CA in both UV photolysis and UV/chlorine processes could be degraded via pseudo-first-order kinetics, while it almost could not be degraded in the dark chlorination process. The observed rate constant (kobs) in UV photolysis was 0.0078 min−1, and increased to 0.0107 min−1 combining with 0.1 mM chlorine. The kobs increased to 0.0447 min−1 with further increasing the chlorine dosage from 0.1 to 1.0 mM, and reached a plateau at higher dosage (greater than 1.0 mM). The higher kobs was obtained at acid solution rather than basic solution. Moreover, the calculated contributions of radical species to kobs indicated that the HO• contributed significantly to CA degradation in acidic conditions, while the reactive chlorine species and UV direct photolysis dominated in neutral and basic solution. The degradation of CA was slightly inhibited in the presence of (1 ∼ 50 mM), barely affected by the presence of Cl− (1 ∼ 200 mM) and greatly suppressed by humic acid (0 ∼ 5 mg l−1). Thirteen main degradation intermediates and three degradation pathways of CA were identified during UV/chlorine process.

Study on preparation of SnO2-TiO2/Nano-graphite composite anode and electro-catalytic degradation of ceftriaxone sodium

In order to improve the electro-catalytic activity and catalytic reaction rate of graphite-like material, Tin dioxide-Titanium dioxide/Nano-graphite (SnO2-TiO2/Nano-G) composite was synthesized by a sol-gel method and SnO2-TiO2/Nano-G electrode was prepared in hot-press approach. The composite was characterized by X-ray photoelectron spectroscopy, fourier transform infrared, Raman, N2 adsorption-desorption, scanning electrons microscopy, transmission electron microscopy and X-ray diffraction. The electrochemical performance of the SnO2-TiO2/Nano-G anode electrode was investigated via cyclic voltammetry and electrochemical impedance spectroscopy. The electro-catalytic performance was evaluated by the degradation of ceftriaxone sodium and the yield of ·OH radicals in the reaction system. The results demonstrated that TiO2, SnO2 and Nano-G were composited successfully, and TiO2 and SnO2 particles dispersed on the surface and interlamination of the Nano-G uniformly. The specific surface area of SnO2 modified anode was higher than that of TiO2/Nano-G anode and the degradation rate of ceftriaxone sodium within 120 min on SnO2-TiO2/Nano-G electrode was 98.7% at applied bias of 2.0 V. The highly efficient electro-chemical property of SnO2-TiO2/Nano-G electrode was attributed to the admirable conductive property of the Nano-G and SnO2-TiO2/Nano-G electrode. Moreover, the contribution of reactive species ·OH was detected, indicating the considerable electro-catalytic activity of SnO2-TiO2/Nano-G electrode.

Abstract B01: Impacts of inulin on bile acids induced colon cancer

Abstract Bile acids are normal components of the luminal contents of gastrointestinal tract but have been reported to cause oxidative damage by stimulating the generation of free oxygen radicals from the mitochondria. Several studies have demonstrated the contribution of reactive species to mutagenesis, carcinogenesis and tumor promotion. There is accumulating evidence to show that some carbohydrates and carbohydrate-containing molecules possess antioxidant ability by inhibiting the production of reactive species. Prebiotics are complex carbohydrates which have been shown to improve gut health when used in combination with probiotics. However, there is paucity of data on how prebiotics alone affect gut health and by which mechanism of action. The reactive oxygen scavenging ability of inulin, a prebiotic, has been shown in vitro in non-cell based system and in mice. The anti-inflammatory effect, through production of short chain fatty acids by fermentable inulin has also been shown. However, the mechanism of inulin in the amelioration of bile acid induced cancer remains unknown. Methods: Three different cell-lines (colon stem cells, human colon carcinoma cells-HCT-116 and control normal colon epithelial cells) will be examined. Cells will be treated separately with secondary bile acids, primary bile acids and prebiotics. Cells will also be treated with microorganisms' filtrate such as probiotics (bifidobacteria) in conjunction with secondary bile acids, primary bile acids or prebiotics. Production of free radicals will be measured using nitro blue tetrazolium chloride assay (NBT) and inflammatory proteins will be measured using RT-PCR. DNA damage will be assessed using Endonuclease 111 enzyme modified Comet assay. In addition, C1 Single-Cell auto pep system will be used for mRNA sequencing of individual cells within the well plate. This study hypothesized that normal cells exposed to secondary bile acids in the presence of inulin may be protected from transformation to cancer cells and this may correlate with decrease in production of reactive radicals and pro-inflammatory proteins. The anti inflammatory ability of short chain fatty acid and antioxidant ability of inulin may possibly be associated with AMP-activated protein kinase (AMPK), phosphatidylinositol 3-kinase (P13-K), NF-κB signaling pathways. Thus inulin and their fermentation/breakdown products may not only stimulate beneficial bacteria in the colon but may directly interfere with absorption and cellular metabolism processes in the colon. Citation Format: Bene Akromaa Afolabi, Sandra Appiah, Azra Pachenari, Lucy Ghali. Impacts of inulin on bile acids induced colon cancer. [abstract]. In: Proceedings of the Third AACR International Conference on Frontiers in Basic Cancer Research; Sep 18-22, 2013; National Harbor, MD. Philadelphia (PA): AACR; Cancer Res 2013;73(19 Suppl):Abstract nr B01.