Continuous Hemodialysis Patients Research Articles

Study of some biochemical and hematological parameters in continuously hemodialysis patients in Kirkuk city

Introduction: The severity of chronic renal failure (CRF) classified by professional guidelines in five stages, stage 5 is a severe illness often called end stage kidney failure or end stage renal disease (ESRD), dialysis may be used for this stage. Dialysis treatments replace some of these functions through diffusion (waste removal) and ultrafiltration (fluid removal). Hemodialysis, is a process of purifying the blood, when the kidneys are not working normally. It is one of three renal replacement therapies (the other two being peritoneal dialysis and renal transplant).
 Materials and Methods: The samples of this study consists of 80 patients (42 males, 38 females) and 85 healthy individuals (43 males, 42 females) from (20 - 70) years old of age. Serum paraoxonase-1 (PON1), `5-nucleatidase, blood urea ( BU), serum creatinine Cr, serum iron (Fe), serum total iron binding capacity (TIBC), Serum feritin, serum amylase activity and serum lipase activity were determined. Some hematological parameters includes packed cell volume (PCV), hemoglobin (Hb), white blood cells count (WBCs), red blood cell count (RBCs) were measured, the erythrocyte sedimentation rate (ESR), Body mass index (BMI) and creatinine clearance Ccl were also measured.
 Results: Decreased levels of some enzymes activity and some biochemical and hematological parameters and increased others in continuous and regular hemodialysis patients in Kirkuk city. Blood urea and serum creatinine showed significant increased (P˂0.05) in their levels, while the creatinine clearance was significantly decreased (P˂0.05) in patients with continuous hemodialysis patients when compared to those of controls. In the present study; there was significant decreased (P˂0.05) in PON-1 in patients when compared to those of controls. However, the serum`5-NT, amylase and lipase activities were significantly increased (P ˂ 0.05) in these patients when compared with serum of normal individuals. In the present study; there was significant decreased in Fe and TIBC concentrations in the serum of patients when compared to those of healthy control individuals (P˂0.05). While the serum ferritin was significantly increased (P˂0.05) in these patients as compared to the controls. In the present study; there was significant decreased (P ˂ 0.05) in Hb and PCV and RBCs concentrations inthese patients when compared to those of controls. While WBCs and ESR was significantly increased (P˂0.05) in these patients as compared to the controls.
 Conclusion: Serum paraoxonase PON -1 activity is the most commonly affected than other biochemical parameters in continuous hemodialysis patients. Anemia, pancreatitis are the common and often an early complication of chronic renal diseases

Exercise influence on the quality of life in hemodialysis patients

Objective To analyze effect of the exercise reducting and improving fistula complications and the quality of life for continuous hemodialysis patients. Methods 106 patients with end-stage renal failure and hemodialysis were randomly divided into all 53 patients in observation group(using yoga exercise intervention)and 53 patients in the control group(no intervention measures).Incidence of venous thrombosis,arterial thrombosis,false aneurysm, vascular complications were observed in patients of two groups.The quality of patients'life after dialysis care situation in two groups was evaluated by a simple scale of health survey Mos SF-36. Results The comparison result of complication occurs case showed that the incidence of venous thrombosis, arterial thrombosis end, false aneurysm, vascular complications in the observation group were respectively 13.21%,0,3.77%and 20.75%;The same indexes were 33.96%,9.43%,15.09%and 58.49% in the control group,and the complications in the observation group were significantly fewer than the control group(χ2=6.33,5.15,3.98,10.44,P<0.01,P=0.02,P=0.04).the improved situation of life quality in the two groups showed physiological function,physical function,bodily pain,g eneral health,vitality, social function,emotional function were significant differences before and after the mental health care in the observation group(t=5.05,4.57,2.85,6.95,10.06,3.28,6.71,8.11,P<0.01);in addition to the physiological functions in the control group,social function,the other were also statistically significant(t=2.42,1.27,2.06,4.54,4.76,2.19,1.46,3.83P<0.02,P<0.05,P<0.01).In addition to the social function,other improvements in the observation group were better than that in the control group after the mental health care(t=3.06,3.59,2.02,3.79,7.14,1.74,4.22,2.25,P<0.05,P<0.01). Conclusion Through Yoga intervention continued dialysis, the patients'own immune system and disease resistance are improved, the patient's ability to withstand continuous hemodialysis are also improved, thereby to increase the effect of continued hemodialysis. Key words: Exercise; Continuous hemodialysis; Fistula complications; Quality of life

Continuous-hemodialysis patients from a psychiatric viewpoint

Continuous-hemodialysis patients from a psychiatric viewpoint