The nature of the crustal deformation of the northeastern margin of the Tibetan Plateau is vital for elucidating the expansion mechanism of the plateau. We installed 21 continuous GNSS stations and obtained a horizontal velocity field with high spatial resolution. We also acquired a line-of-sight(LOS)velocity field with Sentinel-1 images covering the study area from 2014 to 2022. A multi-scale spherical wavelet method was employed to unify the reference frames of GNSS and InSAR data. After unifying the reference frame, the two data types achieve high consistency. Combining GNSS and InSAR velocities yielded the three-dimensional interseismic velocity field in the northeastern margin of the Tibetan Plateau. Furthermore, we analyzed the crustal deformation characteristics based on the three-dimensional deformation field. The crustal deformation exhibits a pronounced northeastward shift relative to the Ordos block, whereas the interior of the Ordos block remains remarkably stationary, behaving as a rigid unit. The Liupanshan fault is primarily characterized by uplift, devoid of any notable horizontal deformation across the fault. The left-lateral strike-slip mainly characterizes the Haiyuan fault.. The maximum east–west deformation velocity on the southern side of the fault is approximately 3.9 mm/yr, decreasing to about 1.0 mm/yr at the eastern end of the fault. The western segment of the West Qinling fault exhibits a minor east–west motion. Our result provides essential data for further study of the crustal deformation patterns.