In order to efficiently prepare continuous fiber reinforced composites with high mechanical property, a macro-micro operation device was developed to arrange fiber with high precision. Continuous carbon fiber reinforced hydroxyapatite (CF/HA) composites with highly precisive fiber arrangement was subsequently prepared according to a demanded performance. The arranged fiber spacing and fiber angle of the CF preforms by this device was 101.15 ± 11.72 μm and 0.14 ± 0.38°, respectively. Compared to the traditional arrangement with the arranged fiber spacing of about 300–500 μm, the arrangement accuracy by this device enhanced about 66 %–80 %. The continuous CF/HA composites with designed fiber spacing prepared by this device possessed synchronously enhanced toughness and strength. Compressive strength of the CF/HA composites with designed fiber spacing of 300 μm (CF03p/HA) increased by 311.54 % compared with pure HA. Fracture toughness of the CF03p/HA composites was 1.68 MPa m1/2. Even though the fiber content in CF03p/HA composites was only one-sixth to one-tenth of that in the composites prepared by the traditional method, the compressive strength was 4.12 times that of pure HA. The study provides an effective method for preparing micro fiber reinforced composites featuring excellent mechanical performance even by adding low fiber content.