Cellular Vehicle-to-Everything (C-V2X) networks provide critical support for intelligently connected vehicles (ICVs) and intelligent transport systems (ITS). C-V2X utilizes vehicle-to-vehicle (V2V) communication technology to exchange safety–critical information among neighbors. V2V communication has stringent high-reliability and low-latency requirements. The existing solutions on resource allocation for V2V communications mainly rely on channel states to optimize resource utilization but fail to consider vehicle safety requirements, which cannot satisfy safety application performance. In this paper, we focus on application-driven channel resource allocation strategy for V2V communications. First, we propose an inter-packet reception model to represent the delay between two consecutive and successful reception packets at a receiver. We then design an application-specific utility function where the utility depends on the packet reception performance and vehicle safety context. Finally, we formulate the channel resource allocation problem as a non-cooperative game model. The game model can guide each node to cooperate and achieve the trade-off between fairness and efficiency in channel resource allocation. The simulation results show that our work can significantly improve the reliability of V2V communications and guarantee the vehicle safety application performance.