Sustainable dietary transition is widely identified essential in addressing the nutrition, environment, and health trilemma. This is particularly important for China, the world's most populous country which is undergoing a rapid dietary structure change. Here, we used a nonlinear optimization algorithm to identify a nutritionally adequate, environmentally friendly, economically affordable, and culturally acceptable diet for each of the 31 provinces in mainland China. We found that province-specific dietary shifts could reduce the carbon, water, land, nitrogen, and phosphorus footprints of China's food consumption by 9.5–25.3%, 10.7–19.1%, 22.4–32.9%, 30.8–40.2%, and 21.4–34.5%, respectively, while meeting the daily recommended intake of essential nutrients and not exceeding current food expenditures. The variation in required food intake was highly province-specific; however, in general, there was a need to reduce the intake of meat, grains, and edible oils and increase the intake of vegetables, fruits, legumes, tubers, and dairy products. Our findings highlight the importance of province-specific diet optimization, which can greatly improve acceptance and feasibility of sustainable dietary transition, guide individuals to change their food consumption behavior, and inform policymakers towards regionally tailored food policies.