Cellular materials have drawn increasing interest in numerous applications due to their promising specific stiffness, strength and energy absorption capacity. In this work, a variety of rather novel lattice topologies pertinent to additive manufacturing are derived and examined. A number of these are derived by free-domain and constrained domain topology optimization procedures, while others are inspired by the triply periodic minimum surface (TPMS) sheet-based topologies. The topology optimization module utilized a single objective function of minimizing strain energy under linear elastic conditions. A total of fifteen different lattice topologies are investigated numerically, including both novel and conventional topologies (e.g. strut-based lattices) and their effective elastic properties are determined with respect to relative density through finite element analysis (FEA). Based on the preliminary FEA results, a number of these topologies are selected of which tessellated lattice structures are fabricated through laser powder bed fusion (LPBF) additive manufacturing technique out of Nylon thermoplastic material. The tessellated lattice structures are experimentally tested in compression and their mechanical performance, including uniaxial modulus, yield strength, and energy absorption capacity (EAC), is assessed. FEA simulations have been conducted using an elastic-plastic constitutive model for the Nylon base material. Both the experimental and numerical results reveal that the mechanical performance of the novel tube-based TPMS lattice P-100 and the combined loading (CL) topology derived through free-domain topology optimization surpasses all other topologies. P-100 uses a primitive TPMS with equal-length tubular connections in each direction, where the tubular length percentage compared to the primitive lattice size is 100%, while CL lattice topology is a free domain topology optimized under compressive loads on the centers of faces, edges, and vertices toward the center. The innovative lattice topologies proposed in the current study, particularly the P-100 and CL topologies, can become crucial in applications where it is necessary to improve the energy absorption capacity, such as sandwich panel cores, supports, and infills for 3D printed components.