ABSTRACT Agriculture is recognized as a significant consumer of water, with projections indicating an increase in consumption due to rising food demand and the impacts of climate change. Therefore, every country must ensure the adequacy and security of water for sustainable uses. This research reviews the water footprint (WF) index as a recent water indicator that measures the human appropriation of water resources for several consumptive uses that qualify decision-makers to manage water with high efficiency in agriculture sectors. Light is shed on the WF concept, virtual water, mechanisms of water use, and the applications in water resources management, as well as methods for assessment with its three components, blue, green, and gray. The comparison between these methods was discussed, and the differences and motives for use were clarified. The good innovation in this review is linking sustainability considerations with the WF, discussing measuring the sustainability of agricultural activities, and deducing the best policies and decisions to meet environmental and economic needs without compromising the requirements of the future. This outcome confirms the effectiveness of applying the WF in enhancing sustainability.