Aldous’ spectral gap conjecture states that the second largest eigenvalue of any connected Cayley graph on the symmetric group Sn with respect to a set of transpositions is achieved by the standard representation of Sn. This celebrated conjecture, which was proved in its general form in 2010, has inspired much interest in searching for other families of Cayley graphs on Sn with the property that the largest eigenvalue strictly smaller than the degree is attained by the standard representation of Sn. In this paper, we prove three results on normal Cayley graphs on Sn possessing this property for sufficiently large n, one of which can be viewed as a generalization of the “normal” case of Aldous’ spectral gap conjecture.