Congenital Single Coronary Artery Research Articles

Percutaneous closure of an unusually large patent ductus arteriosus in a patient with a giant pulmonary artery and congenital single coronary artery

Percutaneous closure of an unusually large patent ductus arteriosus in a patient with a giant pulmonary artery and congenital single coronary artery

Percutaneous closure of an unusually large patent ductus arteriosus in a patient with a giant pulmonary artery and congenital single coronary artery

Percutaneous closure of an unusually large patent ductus arteriosus in a patient with a giant pulmonary artery and congenital single coronary artery

Coronary artery disease in congenital single coronary artery in adults: A Dutch case series.

To assess the current diagnostic and therapeutic management and the clinical implications of congenital single coronary artery (SCA) in adults. We identified 15 patients with a SCA detected from four Dutch angiography centers in the period between 2010 and 2013. Symptomatic patients who underwent routine diagnostic coronary angiography (CAG) for suspected coronary artery disease and who incidentally were found to have isolated SCA were analyzed. Fifteen (7 females) with a mean age of 58.5 ± 13.78 years (range 43-86) had a SCA. Conventional CAG demonstrated congenital isolated SCA originating as a single ostium from the right sinus of Valsalva in 6 patients and originating from the left in 9 patients. Minimal to moderate coronary atherosclerotic changes were found in 4, and severe stenotic lesions in another 4 patients. Seven patients were free of coronary atherosclerosis. Runs of non-sustained ventricular tachycardia were documented in 2 patients, one of whom demonstrated transmural ischemic changes on presentation. Myocardial perfusion scintigraphic evidence of transmural myocardial ischemia was found in 1 patient due to kinking and squeezing of the SCA with an interarterial course between the aorta and pulmonary artery. Multi-slice computed tomography (MSCT) was helpful to delineate the course of the anomalous artery relative to the aorta and pulmonary artery. Percutaneous coronary intervention was successfully performed in 3 patients. Eight patients were managed medically. Arterial bypass graft was performed in 4 patients with the squeezed SCA. SCA may be associated with transient transmural myocardial ischemia and aborted sudden death in the absence of coronary atherosclerosis. The availability and sophistication of MSCT facilitates the delineation of the course of a SCA. We present a Dutch case series and review of the literature.

Coexistence of postpartum cardiomyopathy and single coronary artery anomaly

Postpartum cardiomyopathy (PPCM) is dilated cardiomyopathy seen in the postpartum period in women who no prior history of cardiac diseases. In this case study, coronary angiography was used to determine the etiology of the cardiomyopathy after the decompensated heart failure had regressed. A congenital single coronary artery anomaly was detected by coronary angiography. In this case, PPCM can mimic pneumonia, thus making diagnosis difficult. When there is no response to antibiotic therapy, the obstetrician must consider cardiac disease and appropriate consultation should be obtained as soon as possible. To the best of our knowledge, single coronary artery anomalies coexisting with PPCM has only been documented in one other case in the literature. An association of single coronary artery anomalies with PPCM may be random, or, alternative, might contribute to the composition of the PPCM.

Unexpected Sudden Death of a 19-Year-Old Female with Congenital Single Coronary Artery Ostium during Exertion

Coronary artery anomalies are associated often with myocardial ischemia or sudden cardiac death. A 19-year-old woman who participated in an exertive game lost consciousness upon one such exertion. She was taken to a hospital where she died on the same day. An autopsy revealed that she had bifurcated coronary arteries, which arose from one coronary ostium in the left sinus of Valsalva. The right coronary artery arose from the left sinus and traveled between the aorta and the pulmonary trunk. The heart as well as the cardiac conduction system depended exclusively on the single coronary artery ostium for oxygenated blood supply, and the unbalanced blood distribution on her exertion probably led to sudden cardiac death. The case highlights the medicolegal importance of unexpected sudden cardiac death related to an anomalous origin of the coronary arteries.

Congenital single coronary artery with an absent left main coronary artery

Congenital single coronary artery with an absent left main coronary artery

Unexpected sudden death of a 12-year-old male with congenital single coronary artery

A rare autopsy case of a 12-year-old male with a single coronary artery is reported in which he suddenly and unexpectedly died after a brief period of physical and mental excitation. The single coronary artery originated from the left aortic sinus, then branched out the left circumflex artery and afterwards descended as the left anterior descending artery, while the right coronary artery originated almost at a right angle from the left anterior descending artery. The entire heart as well as the cardiac conduction system depended exclusively on the single coronary artery for oxygenated blood supply, and the unbalanced blood distribution on his exertion probably led to sudden cardiac death. Moreover, in this case, both the deceased's mother (at the age of 20 years) and grandmother on the mother's side died suddenly, thus suggesting a possibility of maternal transmission of this congenital anomaly in his family.

Congenital single coronary artery in man: Report of nine new cases, one having thrombosis with right ventricular and atrial (auricular) infarction

Nine new cases of absence of a coronary artery are added to twenty-two previously reported cases of this anomaly. Three of these nine patients had occlusion at one or more points of the single coronary artery, with resultant myocardial infarction. One patient had massive infarction of the right ventricle and auricle, and a unique series of electrocardiograms was recorded. These indicate that atrial infarction should be suspected with the occurrence of: (1) atrial arrhythmias, especially if changing rapidly in type; (2) atrioventricular block; (3) changing contour of P or f waves; (4) changing contour of the P-T A segment or interval and of the atrial T wave (T A) if evident, as it may be with dissociation or prolonged P-R intervals. The embryologic and clinical features of the anomaly are discussed and mechanisms for its production are propounded. This anomaly is compatible with normal cardiac function, but adds extra hazard in the presence of coronary artery disease because the available collateral anastomoses must be utilized early in life.