The aim of this technical note is to describe the Cycle 46 reference configuration of the HARMONIE-AROME convection-permitting numerical weather prediction model. HARMONIE-AROME is one of the canonical system configurations that is developed, maintained, and validated in the ACCORD consortium, a collaboration of 26 countries in Europe and northern Africa on short-range mesoscale numerical weather prediction. This technical note describes updates to the physical parametrizations, both upper-air and surface, configuration choices such as lateral boundary conditions, model levels, horizontal resolution, model time step, and databases associated with the model, such as for physiography and aerosols. Much of the physics developments are related to improving the representation of clouds in the model, including developments in the turbulence, shallow convection, and statistical cloud scheme, as well as changes in radiation and cloud microphysics concerning cloud droplet number concentration and longwave cloud liquid optical properties. Near real-time aerosols and the ICE-T microphysics scheme, which improves the representation of supercooled liquid, and a wind farm parametrization have been added as options. Surface-wise, one of the main advances is the implementation of the lake model FLake. An outlook on upcoming developments is also included.