This study investigated the effect of a 12-week resistance exercise program on bone metabolism, and fall efficacy in elderly women aged 75-85 years. Participants were divided into a resistance exercise group (REG, n=15) and a control group(CG, n=15). To test the time interactions between the REG and the CG, to collected data were analyzed using two-way repeated measures ANOVA. A paired t-test was used for the within-group pre-post differences, and an independent t-test was used for the between-group differences. The level of significance was set at .05. As a result, parathyroid hormone main effect of time was detected between the REG and the CG(p<.05), osteocalcin group×time interaction effect for osteocalcin was found between the REG and the CG(p<.001), fall efficacy group×time interaction effect for fall efficacy was found between the REG and the CG(p<.001). Taken together, it is thought that the implementation of regular resistance exercises for 12-week in elderly women has a positive effect on bone metabolism and fall efficacy, reducing fear of falls and preventing osteoporosis, creating confidence in physical activity, which is very helpful in improving quality of life.