As a source substitution technology that reduces pollutants emission and optimizes sinter properties, H2-rich gas injection-assisted iron ore sintering holds significant practical value. This study analyzed the adaptability of this technology to different ore blend ratios and basicity levels by comparing sintering indexes, pore structure, mineral phase composition, and metallurgical performance before and after H2-rich gas injection. The carbon emission reduction following H2-rich gas injection was calculated. The results indicate that increasing the proportion of high-silica, low-alumina ore (Ore-A) and basicity, along with H2-rich gas injection, can effectively enhance sinter yield and quality, but shrink the pore structure of sinter. Under H2-rich gas injection conditions, decreasing Ore-A ratios and increasing basicity can augment SFCA phase formation and mineral phase uniformity, thereby improving the anti-pulverization ability and reductivity of the sinter. H2-rich gas injection presents better adaptability to sintered ore with lower Ore-A ratio and basicity, which can achieve greater improvements in the sintering indexes, RDI, and RI. For a 265 m2 sinter plant producing sinter with 18 wt.% Ore-A and 2.0 basicity, annual CO2 emissions can be reduced by approximately 40,000 t.